Clinical Trials Updated in 2026

NCT06411691 | RECRUITING | PHASE1

54 participants

KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-11-04
Completion:: 2029-11-01

Conditions

Colorectal Cancer
Pancreatic Cancer

Interventions

DRUG

No Results Yet

NCT06388200 | ACTIVE_NOT_RECRUITING | PHASE3

140 participants

A Phase 3 Study Of OCU400 Gene Therapy for the Treatment Of Retinitis Pigmentosa

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-06-18
Completion:: 2027-02-12

Conditions

Retinitis Pigmentosa

Interventions

GENETIC

No Results Yet

NCT06387511 | COMPLETED | NA

3814 participants

Increasing Measles Vaccination Coverage Through Supplementation With an SQ-LNS Incentive in Children Aged 6-23 Months

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-05-07
Completion:: 2025-06-26

Conditions

Immunization Coverage
Vaccination
Nutrition

Interventions

DIETARY_SUPPLEMENT
BEHAVIORAL

No Results Yet

NCT06382324 | RECRUITING | NA

80 participants

The Psychological Impact of Mindfulness Intervention to Anterior Cruciate Ligament Reconstruction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-04-23
Completion:: 2027-06-30

Conditions

Anterior Cruciate Ligament (Acl) Reconstruction

Interventions

BEHAVIORAL

No Results Yet

NCT06376994 | RECRUITING | PHASE3

770 participants

Multi-Center Clean Air Randomized Controlled Trial in COPD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-05-24
Completion:: 2029-08-31

Conditions

Chronic Obstructive Pulmonary Disease (COPD)

Interventions

DEVICE

No Results Yet

NCT06374875 | RECRUITING | PHASE4

120 participants

Fibrosis Lessens After Metabolic Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-07-11
Completion:: 2029-05-31

Conditions

Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD)
Non-Alcoholic Fatty Liver Disease
Metabolic Dysfunction-Associated Steatohepatitis (MASH)
Liver Fibrosis
Obesity

Interventions

PROCEDURE
DRUG

No Results Yet

NCT06367257 | RECRUITING | NA

148 participants

App-based Recording and Optimization of the Nutritional Status in Patients With Head and Neck Tumors During and After Radio(Chemo)Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-02-29
Completion:: 2027-04-30

Conditions

Squamous Cell Carcinoma of Head and Neck

Interventions

PROCEDURE
OTHER

No Results Yet

NCT06365021 | COMPLETED | NA

75 participants

ACT for Syndromic and Subsyndromic Depression in Bipolar Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-05-06
Completion:: 2025-10-28

Conditions

Bipolar Disorder

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06352372 | COMPLETED | PHASE2

6 participants

Safety and Efficacy of tPBM for Epileptiform Activity in Autism

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-07-01
Completion:: 2026-02-10

Conditions

Autism Spectrum Disorder
EEG With Periodic Abnormalities
Epilepsy
Neurodevelopmental Disorders
Neurological Disorder

Interventions

DEVICE

Results Available

NCT06347159 | ACTIVE_NOT_RECRUITING | PHASE2

79 participants

A Study of EDG-7500 in Adults With Hypertrophic Cardiomyopathy (CIRRUS-HCM)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-04-11
Completion:: 2027-12-31

Conditions

Hypertrophic Cardiomyopathy

Interventions

DRUG

No Results Yet

NCT06333483 | ACTIVE_NOT_RECRUITING | PHASE1

16 participants

Obe-cel in Adolescent [Applicable in UK Only] and Adult Severe, Refractory Systemic Lupus Erythematosus

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-02-02
Completion:: 2027-09-30

Conditions

Systemic Lupus Erythematosus

Interventions

BIOLOGICAL

No Results Yet

NCT06325722 | RECRUITING | NA

42 participants

Diet Order Effects of Low Fat vs. Low Carb Diets on Body Fat Change

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-08-28
Completion:: 2029-11-30

Conditions

Overweight
Obesity

Interventions

OTHER

No Results Yet

NCT06323447 | ACTIVE_NOT_RECRUITING

210 participants

Pivotal Study to Validate a Novel System to Non-Invasively Detect Severe Neutropenia

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-12-15
Completion:: 2027-06-30

Conditions

Diffuse Large B Cell Lymphoma
Multiple Myeloma

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06317987 | ACTIVE_NOT_RECRUITING | NA

74 participants

Addressing Barriers to Care for Substance Use Disorder Pilot Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-07-09
Completion:: 2025-02-11

Conditions

Drug Use Disorders
Illicit Drug Use
Alcohol-Related Disorders

Interventions

BEHAVIORAL

Results Available

NCT06314425 | ACTIVE_NOT_RECRUITING | NA

50 participants

Zirconia Implants: Practice-based Evidence

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-01-03
Completion:: 2025-04-24

Conditions

Dental Implants
Ceramic Implant

Interventions

PROCEDURE

No Results Yet

NCT06305793 | COMPLETED | PHASE2

200 participants

RECOVER-AUTONOMIC: Platform Protocol, Appendix A (IVIG)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-05-08
Completion:: 2026-03-23

Conditions

Long COVID
Long Coronavirus Disease 2019 (Covid19)
Long Covid-19

Interventions

DRUG
BEHAVIORAL

No Results Yet

NCT06305624 | RECRUITING | NA

298 participants

Implementation of Mobile-based Programs for Alcohol Cessation in Treatment of Alcohol-associated Liver Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-06-01
Completion:: 2027-10-31

Conditions

Alcohol Use Disorder
Alcohol-related Liver Disease

Interventions

DEVICE

No Results Yet

NCT06290765 | WITHDRAWN | PHASE4

0 participants

Efficacy and Safety of Ropeginterferon Alfa 2b (P1101) for Patients With Polycythemia Vera

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-08-01
Completion:: 2026-12-31

Conditions

Polycythemia Vera
Myeloproliferative Neoplasm

Interventions

DRUG
PROCEDURE

No Results Yet

NCT06287944 | RECRUITING | PHASE1

15 participants

225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-07-01
Completion:: 2028-05-19

Conditions

Acute Lymphoblastic Leukemia
Acute Myeloid Leukemia
Myelodysplastic Syndrome

Interventions

DRUG
RADIATION
BIOLOGICAL
PROCEDURE

No Results Yet

NCT06285916 | COMPLETED | PHASE2

93 participants

A Study to Assess the Efficacy, Safety, and Tolerability of Oral NORA520 in Adults With Severe Postpartum Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-03-28
Completion:: 2025-09-11

Conditions

Depression, Postpartum
Postpartum Depression
Post-partum Depression
Postnatal Depression
Post-Natal Depression

Interventions

DRUG

No Results Yet

NCT06238778 | COMPLETED | PHASE2

227 participants

Phase 2b Trial Comparing HDV-Insulin Lispro to Insulin Lispro in Adults With Type 1 Diabetes Receiving Insulin Degludec

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-12-28
Completion:: 2025-10-27

Conditions

Diabetes Mellitus, Type 1

Interventions

DRUG

No Results Yet

NCT06230822 | COMPLETED | PHASE1

9 participants

Safety, Tolerability and Efficacy of VUM02 Injection in Treatment of Idiopathic Pulmonary Fibrosis (IPF)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-03-05
Completion:: 2025-03-13

Conditions

Idiopathic Pulmonary Fibrosis

Interventions

DRUG

No Results Yet

NCT06217601 | ACTIVE_NOT_RECRUITING | NA

1024 participants

Impact Evaluation of the Digital Connect Project for Homebound Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-06-01
Completion:: 2026-06-30

Conditions

Aging Well

Interventions

BEHAVIORAL

No Results Yet

NCT06202573 | COMPLETED | NA

124 participants

Effect of Step Count on Edema After Rhinoplasty

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-01-05
Completion:: 2025-01-01

Conditions

Reduce Edema and Ecchymosis After Rhinoplasty

Interventions

PROCEDURE

No Results Yet

NCT06192511 | RECRUITING | NA

5980 participants

Implementing a Novel Consent Process for Biospecimen Research After Newborn Screening

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-05-15
Completion:: 2027-11-15

Conditions

Implementation Science
Informed Consent
Neonatal Screening

Interventions

BEHAVIORAL

No Results Yet

NCT06176352 | COMPLETED | PHASE3

280 participants

A Study to Evaluate the Efficacy and Safety of Faricimab in Patients With Choroidal Neovascularization Secondary to Pathologic Myopia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-03-06
Completion:: 2026-05-22

Conditions

Choroidal Neovascularization Secondary to Pathologic Myopia

Interventions

DRUG
PROCEDURE

No Results Yet

NCT06139016 | COMPLETED | NA

7 participants

Using Virtual Reality to Control the Audio-visual Inputs During Ketamine/Esketamine Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-07-11
Completion:: 2024-11-27

Conditions

Depression

Interventions

DEVICE

Results Available

NCT06102590 | RECRUITING | NA

324 participants

Oxygen Extraction-guided Transfusion

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-11-04
Completion:: 2026-12-01

Conditions

Blood Transfusion

Interventions

OTHER

No Results Yet

NCT06089057 | ENROLLING_BY_INVITATION | NA

30 participants

Pro-social Power Training Activity for Aging and Well-being With Chronic Kidney Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-07-15
Completion:: 2028-09-29

Conditions

Lower Extremity Muscle Strength

Interventions

BEHAVIORAL

No Results Yet

NCT06087627 | ACTIVE_NOT_RECRUITING

110 participants

A Non-interventional Study to Describe the Dupilumab Long-term Treatment, Safety and Patient Reported Outcomes in Chronic Nodular Prurigo (Prurigo Nodularis) in Clinical Routine

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-12-27
Completion:: 2026-06-29

Conditions

Prurigo Nodularis

Interventions

DRUG

No Results Yet

NCT06077227 | RECRUITING | NA

20 participants

Immersive Healing: The Therapeutic Potential of Virtual Reality

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-12-21
Completion:: 2026-10-31

Conditions

Phantom Limb Pain (PLP)

Interventions

DEVICE
OTHER

No Results Yet

NCT06069726 | RECRUITING | PHASE2

80 participants

A Multicenter Trial to Identify Optimal Atezolizumab Biomarkers in the Setting of Recurrent Glioblastoma. The MOAB Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-03-21
Completion:: 2028-01-01

Conditions

Recurrent Glioblastoma

Interventions

DRUG

No Results Yet

NCT06066580 | ENROLLING_BY_INVITATION | PHASE2

260 participants

Open-Label Extension of EDG-5506 in Participants With Becker Muscular Dystrophy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-11-02
Completion:: 2031-02-28

Conditions

Becker Muscular Dystrophy

Interventions

DRUG

No Results Yet

NCT06055959 | RECRUITING | PHASE2/PHASE3

8 participants

A Study to Evaluate Subcutaneous Zilucoplan in Pediatric Participants With Generalized Myasthenia Gravis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-10-16
Completion:: 2026-11-16

Conditions

Generalized Myasthenia Gravis

Interventions

DRUG

No Results Yet

NCT06039605 | COMPLETED | NA

140 participants

Priming Expectations and Motor Learning With tDCS

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-10-23
Completion:: 2025-04-16

Conditions

Expectations
Motor Learning

Interventions

DEVICE

Results Available

NCT06032923 | RECRUITING | PHASE1/PHASE2

78 participants

Double-blind Placebo Controlled Study to Evaluate the Effect of NAD+ Boosting With Nicotinamide Riboside on Immunometabolism and Immunity in Systemic Lupus Erythematosus

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-03-13
Completion:: 2028-08-01

Conditions

Systemic Lupus Erythematosus (Sle)

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06018558 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

60 participants

Study to Assess the Safety and Efficacy of OCU410 for Geographic Atrophy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-02-23
Completion:: 2026-02-03

Conditions

Geographic Atrophy

Interventions

GENETIC

No Results Yet

NCT06014424 | RECRUITING | PHASE2

40 participants

Cannabidiol Medication Intervention Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-09-27
Completion:: 2026-12-29

Conditions

Alzheimer Disease

Interventions

DRUG
OTHER

No Results Yet

NCT06007690 | ACTIVE_NOT_RECRUITING | PHASE3

108 participants

A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-12-06
Completion:: 2027-11-15

Conditions

Choroidal Melanoma
Indeterminate Lesions
Uveal Melanoma
Ocular Melanoma

Interventions

DRUG
DEVICE

No Results Yet

NCT05987423 | COMPLETED | PHASE3

131 participants

Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Thyroid Eye Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-10-26
Completion:: 2025-07-08

Conditions

Thyroid Eye Disease
TED

Interventions

DRUG

Results Available