Clinical Trials

NCT05850689 | RECRUITING | PHASE3

470 participants

Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-05-02
Completion:: 2027-04-05

Conditions

Major Depressive Disorder

Interventions

DRUG

No Results Yet

NCT05838573 | COMPLETED | PHASE3

120 participants

Metformin Treatment on Cognitive Impairment of Schizophrenia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-05-08
Completion:: 2026-06-08

Conditions

Schizophrenia

Interventions

DRUG
OTHER

No Results Yet

NCT05833048 | RECRUITING | NA

75 participants

Rectus Sheath Block in Cardiac Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-07-29
Completion:: 2026-10-30

Conditions

Cardiac Disease
Postoperative Pain

Interventions

PROCEDURE

No Results Yet

NCT05828082 | ACTIVE_NOT_RECRUITING | PHASE2

20 participants

Testing the Effect of M1774 on Hard-to-Treat Refractory SPOP-mutant Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-10-16
Completion:: 2027-01-01

Conditions

Castration-Resistant Prostate Carcinoma
Metastatic Castration-Resistant Prostate Carcinoma
Refractory Prostate Carcinoma
Stage IVB Prostate Cancer AJCC v8

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05828056 | RECRUITING

100 participants

Prediction on the Recurrence of Manic and Depressive Episodes in Bipolar Disorder

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-31
Start Date:: 2020-03-02
Completion:: 2027-12-31

Conditions

Bipolar Disorder
Depressive Disorder

Interventions

DEVICE

No Results Yet

NCT05810636 | ENROLLING_BY_INVITATION

200 participants

Hyperactivity Assessment in Children With Attention-deficit Hyperactivity Disorder

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-31
Start Date:: 2022-02-16
Completion:: 2026-12-31

Conditions

Attention Deficit Disorder With Hyperactivity

Interventions

DEVICE

No Results Yet

NCT05806606 | COMPLETED | NA

232 participants

Effect and Cost Effectiveness of a Dyadic Empowerment-based Heart Failure Management Program for Self-care

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-04-17
Completion:: 2025-09-01

Conditions

Heart Failure
Self Care
Empowerment
Transitional Care
Disease Management

Interventions

OTHER

No Results Yet

NCT05803382 | RECRUITING | PHASE1

30 participants

Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-11-08
Completion:: 2027-06-30

Conditions

Metastatic Colorectal Carcinoma
Metastatic Malignant Solid Neoplasm
Stage IV Colorectal Cancer AJCC v8
Unresectable Colorectal Carcinoma
Unresectable Malignant Solid Neoplasm

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05802329 | RECRUITING | PHASE1

24 participants

Phase I Study to Assess the Safety and Efficacy of OCU200 for Center-Involved Diabetic Macular Edema (DME)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-01-13
Completion:: 2026-07-31

Conditions

Center Involved Diabetic Macular Edema
Diabetic Macular Edema

Interventions

DRUG

No Results Yet

NCT05801185 | ENROLLING_BY_INVITATION | NA

20 participants

Single Nuclei Sequencing in Human Skeletal Muscle After Unloading

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-03-05
Completion:: 2026-07-31

Conditions

Unilateral Lower Limb Suspension

Interventions

OTHER

No Results Yet

NCT05794555 | COMPLETED | PHASE3

233 participants

LiveSMART Trial to Prevent Falls in Patients With Cirrhosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-06-13
Completion:: 2025-03-07

Conditions

Cirrhosis, Liver
Portal Hypertension

Interventions

BEHAVIORAL
DRUG

Results Available

NCT05784441 | ACTIVE_NOT_RECRUITING | PHASE1

21 participants

A Study of JNJ-90009530 in Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma (r/r B-NHL)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-11-06
Completion:: 2027-01-06

Conditions

Relapsed or Refractory B Cell Non-Hodgkin Lymphoma

Interventions

DRUG

No Results Yet

NCT05759923 | RECRUITING | PHASE1

40 participants

First-in-human Phase I Study to Evaluate Safety, Tolerability and Antineoplastic Activity of OATD-02 in Patients With Selected Advanced and/or Metastatic Solid Tumours

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-01-26
Completion:: 2027-03-31

Conditions

Advanced Ovarian Carcinoma
Advanced Renal Cell Carcinoma
Advanced Pancreatic Carcinoma
Advanced Colorectal Carcinoma
Metastatic Pancreatic Carcinoma
Metastatic Colorectal Carcinoma
Metastatic Renal Cell Carcinoma
Metastatic Ovarian Carcinoma

Interventions

DRUG

No Results Yet

NCT05742165 | COMPLETED | NA

29 participants

Time Restricted Eating for Weight Loss Maintenance

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-07-17
Completion:: 2025-01-06

Conditions

Obesity

Interventions

BEHAVIORAL

Results Available

NCT05724108 | ACTIVE_NOT_RECRUITING | PHASE2

94 participants

Testing the Effectiveness of an Anti-cancer Drug, Triapine, When Used With Targeted Radiation-based Treatment (Lutetium Lu 177 Dotatate), Compared to Lutetium Lu 177 Dotatate Alone for Metastatic Neuroendocrine Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-08-30
Completion:: 2026-12-09

Conditions

Metastatic Neuroendocrine Tumor

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05715255 | ACTIVE_NOT_RECRUITING | NA

400 participants

Adaptive Symptom Self-Management Immunotherapy Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-05-08
Completion:: 2027-04-30

Conditions

Breast Cancer
Colon Cancer
Lung Cancer
Skin Cancer
Rectum Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT05711615 | RECRUITING | PHASE1

30 participants

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-02-06
Completion:: 2026-11-03

Conditions

Metastatic Dedifferentiated Liposarcoma
Metastatic Leiomyosarcoma
Metastatic Myxofibrosarcoma
Metastatic Sarcoma
Metastatic Synovial Sarcoma
Metastatic Undifferentiated Pleomorphic Sarcoma
Unresectable Dedifferentiated Liposarcoma
Unresectable Leiomyosarcoma
Unresectable Myxofibrosarcoma
Unresectable Sarcoma
Unresectable Synovial Sarcoma
Unresectable Undifferentiated Pleomorphic Sarcoma

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05703854 | SUSPENDED | PHASE1/PHASE2

50 participants

Study of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and Osteosarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-03-29
Completion:: 2027-09-30

Conditions

Advanced Renal Cell Carcinoma
Advanced Mesothelioma
Advanced Osteosarcoma

Interventions

DRUG

No Results Yet

NCT05702034 | ACTIVE_NOT_RECRUITING | PHASE3

12532 participants

A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-02-15
Completion:: 2026-11-11

Conditions

Ischemic Stroke; Ischemic Attack, Transient

Interventions

DRUG

No Results Yet

NCT05695391 | TERMINATED | PHASE3

2 participants

Safety and Efficacy of FVIIa to Prevent Excessive Bleeding in Hemophilia Patients With Inhibitors Undergoing Major Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-06-07
Completion:: 2025-05-28

Conditions

Hemophilia

Interventions

BIOLOGICAL

Results Available

NCT05693571 | ACTIVE_NOT_RECRUITING | NA

48 participants

Engagement in CHildhood-Onset Systemic Lupus

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-12-05
Completion:: 2027-02-28

Conditions

Lupus Erythematosus, Systemic
Depression

Interventions

BEHAVIORAL

No Results Yet

NCT05691491 | RECRUITING | PHASE1/PHASE2

42 participants

Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-09-28
Completion:: 2027-03-01

Conditions

Advanced Malignant Solid Neoplasm
Advanced Microsatellite Stable Colorectal Carcinoma
Hematopoietic and Lymphatic System Neoplasm
Metastatic Malignant Solid Neoplasm
Metastatic Microsatellite Stable Colorectal Carcinoma
Stage III Colorectal Cancer AJCC v8
Stage IV Colorectal Cancer AJCC v8

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05685602 | SUSPENDED | PHASE1

43 participants

CA-4948 Added to Standard Chemotherapy to Treat Metastatic or Unresectable Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-06-12
Completion:: 2027-04-30

Conditions

Metastatic Pancreatic Ductal Adenocarcinoma
Stage III Pancreatic Cancer AJCC v8
Stage IV Pancreatic Cancer AJCC v8
Unresectable Pancreatic Ductal Adenocarcinoma

Interventions

PROCEDURE
BIOLOGICAL
DRUG

No Results Yet

NCT05673551 | ENROLLING_BY_INVITATION | NA

220 participants

VR-PAT During Home Burn Dressings - Multisite

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-01-16
Completion:: 2027-12-01

Conditions

Burns
Acute Pain
Procedural Pain
Injuries
Pediatric ALL

Interventions

OTHER

No Results Yet

NCT05673200 | SUSPENDED | PHASE1

32 participants

Testing the Addition of an Anti-cancer Drug, ASTX727 (Cedazuridine, Decitabine), to Chemotherapy (Paclitaxel) and Immunotherapy (Pembrolizumab) for Metastatic Triple-Negative Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-09-25
Completion:: 2027-02-23

Conditions

Anatomic Stage III Breast Cancer AJCC v8
Anatomic Stage IV Breast Cancer AJCC v8
Metastatic Triple-Negative Breast Carcinoma
Unresectable Triple-Negative Breast Carcinoma

Interventions

PROCEDURE
DRUG
BIOLOGICAL

No Results Yet

NCT05669989 | ENROLLING_BY_INVITATION | PHASE2

70 participants

International Treatment-extension Study in Adult Participants With Multiple Myeloma and Who Have Derived Clinical Benefit From Isatuximab

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-04-05
Completion:: 2028-11-30

Conditions

Plasma Cell Myeloma

Interventions

DRUG

No Results Yet

NCT05669664 | ACTIVE_NOT_RECRUITING | PHASE2

21 participants

Testing the Anti-cancer Drug Darolutamide in Patients With Testosterone-Driven Salivary Gland Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-07-20
Completion:: 2026-11-30

Conditions

Locally Advanced Salivary Gland Carcinoma
Metastatic Salivary Gland Carcinoma
Recurrent Salivary Gland Carcinoma
Unresectable Salivary Gland Carcinoma

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05663866 | ACTIVE_NOT_RECRUITING | PHASE2

68 participants

Premedication to Reduce Amivantamab Associated Infusion Related Reactions

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-05-18
Completion:: 2024-03-29

Conditions

Carcinoma, Non-Small-Cell Lung

Interventions

DRUG

Results Available

NCT05645224 | ACTIVE_NOT_RECRUITING | NA

40 participants

VR-PAT for Pain and Anxiety Management During Pediatric Dermatologic Laser Procedures

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-01-09
Completion:: 2025-11-14

Conditions

Procedural Anxiety
Procedural Pain

Interventions

OTHER

No Results Yet

NCT05625659 | RECRUITING | NA

2032 participants

Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breasts

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-03-24
Completion:: 2027-07-31

Conditions

Breast Cancer

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05610059 | COMPLETED | NA

200 participants

Improving Hypertension Medication Adherence for Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2022-11-02
Completion:: 2025-03-14

Conditions

Aging
Medication Adherence
Hypertension

Interventions

OTHER

Results Available

NCT05609786 | COMPLETED | NA

440 participants

Dissemination and Implementation of a Web-based Relationship Safety App, myPlanKenya, for Women at Risk for Intimate Partner Violence in Nairobi, Kenya

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2022-06-22
Completion:: 2024-12-31

Conditions

Violence, Domestic
Violence, Sexual
Violence, Gender-Based

Interventions

BEHAVIORAL

Results Available

NCT05589402 | COMPLETED | PHASE1

52 participants

Temporary Inactivation of Strong Muscle Sensation to Improve Rehabilitation Interventions in SCI

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2019-06-04
Completion:: 2026-07-15

Conditions

Spinal Cord Injuries
Spine Disease
Stroke

Interventions

DRUG
OTHER

No Results Yet

NCT05568264 | ACTIVE_NOT_RECRUITING | NA

222 participants

Effects of a Physical Therapy Intervention on Motor Delay in Infants Admitted to a Neonatal Intensive Care Unit

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2022-10-01
Completion:: 2026-12-31

Conditions

Motor Delay
Premature Birth
Intraventricular Hemorrhage
Hypoxic-Ischemic Encephalopathy
Bronchopulmonary Dysplasia

Interventions

OTHER

No Results Yet

NCT05568095 | ACTIVE_NOT_RECRUITING | PHASE3

1040 participants

A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2022-11-21
Completion:: 2026-08-31

Conditions

Advanced Upper Gastrointestinal Tract Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT05567640 | RECRUITING | NA

1800 participants

Using Machine Learning to Optimize User Engagement and Clinical Response to Digital Mental Health Interventions

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-04-12
Completion:: 2027-07-31

Conditions

Anxiety Disorders and Symptoms
Depressive Symptoms

Interventions

BEHAVIORAL

No Results Yet

NCT05537857 | ACTIVE_NOT_RECRUITING | NA

66 participants

Racial/Ethnic in Calcium and Sodium Metabolism

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-03-01
Completion:: 2026-08-31

Conditions

Healthy

Interventions

OTHER

No Results Yet

NCT05524532 | COMPLETED | PHASE3

101 participants

Effects of Immulina TM Supplements With PASC Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-07-20
Completion:: 2025-07-29

Conditions

Post Acute COVID-19 Syndrome

Interventions

DRUG
DIETARY_SUPPLEMENT

No Results Yet

NCT05508035 | RECRUITING | PHASE3

488 participants

The Effect of Sacubitril/Valsartan Versus Ramipril on Left Ventricular Function and Remodeling in Patients With Ischemic Heart Failure With Mid-range Ejection Fraction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-07-13
Completion:: 2028-08-31

Conditions

Heart Failure With Moderately Reduced Ejection Fraction

Interventions

DRUG

No Results Yet

NCT05488314 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

57 participants

A Study of Amivantamab and Capmatinib Combination Therapy in Unresectable Metastatic Non-small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2022-12-13
Completion:: 2027-04-28

Conditions

Carcinoma, Non-Small-Cell Lung

Interventions

DRUG

No Results Yet