Clinical Trials

NCT05759923 | RECRUITING | PHASE1

40 participants

First-in-human Phase I Study to Evaluate Safety, Tolerability and Antineoplastic Activity of OATD-02 in Patients With Selected Advanced and/or Metastatic Solid Tumours

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-01-26

Completion:

2027-03-31

Conditions

• Advanced Ovarian Carcinoma
• Advanced Renal Cell Carcinoma
• Advanced Pancreatic Carcinoma
• Advanced Colorectal Carcinoma
• Metastatic Pancreatic Carcinoma
• Metastatic Colorectal Carcinoma
• Metastatic Renal Cell Carcinoma
• Metastatic Ovarian Carcinoma

Interventions

• DRUG

No Results Yet

NCT05742165 | COMPLETED | NA

29 participants

Time Restricted Eating for Weight Loss Maintenance

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-07-17

Completion:

2025-01-06

Conditions

• Obesity

Interventions

• BEHAVIORAL

Results Available

NCT05724108 | ACTIVE_NOT_RECRUITING | PHASE2

94 participants

Testing the Effectiveness of an Anti-cancer Drug, Triapine, When Used With Targeted Radiation-based Treatment (Lutetium Lu 177 Dotatate), Compared to Lutetium Lu 177 Dotatate Alone for Metastatic Neuroendocrine Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-08-30

Completion:

2026-12-09

Conditions

• Metastatic Neuroendocrine Tumor

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05715255 | ACTIVE_NOT_RECRUITING | NA

400 participants

Adaptive Symptom Self-Management Immunotherapy Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-05-08

Completion:

2027-04-30

Conditions

• Breast Cancer
• Colon Cancer
• Lung Cancer
• Skin Cancer
• Rectum Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT05711615 | RECRUITING | PHASE1

30 participants

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2024-02-06

Completion:

2026-11-03

Conditions

• Metastatic Dedifferentiated Liposarcoma
• Metastatic Leiomyosarcoma
• Metastatic Myxofibrosarcoma
• Metastatic Sarcoma
• Metastatic Synovial Sarcoma
• Metastatic Undifferentiated Pleomorphic Sarcoma
• Unresectable Dedifferentiated Liposarcoma
• Unresectable Leiomyosarcoma
• Unresectable Myxofibrosarcoma
• Unresectable Sarcoma
• Unresectable Synovial Sarcoma
• Unresectable Undifferentiated Pleomorphic Sarcoma

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05703854 | SUSPENDED | PHASE1/PHASE2

50 participants

Study of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and Osteosarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-03-29

Completion:

2027-09-30

Conditions

• Advanced Renal Cell Carcinoma
• Advanced Mesothelioma
• Advanced Osteosarcoma

Interventions

• DRUG

No Results Yet

NCT05702034 | ACTIVE_NOT_RECRUITING | PHASE3

12532 participants

A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-02-15

Completion:

2026-11-11

Conditions

• Ischemic Stroke; Ischemic Attack, Transient

Interventions

• DRUG

No Results Yet

NCT05695391 | TERMINATED | PHASE3

2 participants

Safety and Efficacy of FVIIa to Prevent Excessive Bleeding in Hemophilia Patients With Inhibitors Undergoing Major Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2024-06-07

Completion:

2025-05-28

Conditions

• Hemophilia

Interventions

• BIOLOGICAL

Results Available

NCT05693571 | ACTIVE_NOT_RECRUITING | NA

48 participants

Engagement in CHildhood-Onset Systemic Lupus

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2024-12-05

Completion:

2027-02-28

Conditions

• Lupus Erythematosus, Systemic
• Depression

Interventions

• BEHAVIORAL

No Results Yet

NCT05691491 | RECRUITING | PHASE1/PHASE2

42 participants

Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-09-28

Completion:

2027-03-01

Conditions

• Advanced Malignant Solid Neoplasm
• Advanced Microsatellite Stable Colorectal Carcinoma
• Hematopoietic and Lymphatic System Neoplasm
• Metastatic Malignant Solid Neoplasm
• Metastatic Microsatellite Stable Colorectal Carcinoma
• Stage III Colorectal Cancer AJCC v8
• Stage IV Colorectal Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05685602 | SUSPENDED | PHASE1

43 participants

CA-4948 Added to Standard Chemotherapy to Treat Metastatic or Unresectable Pancreatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-06-12

Completion:

2027-04-30

Conditions

• Metastatic Pancreatic Ductal Adenocarcinoma
• Stage III Pancreatic Cancer AJCC v8
• Stage IV Pancreatic Cancer AJCC v8
• Unresectable Pancreatic Ductal Adenocarcinoma

Interventions

• PROCEDURE
• BIOLOGICAL
• DRUG

No Results Yet

NCT05673551 | ENROLLING_BY_INVITATION | NA

220 participants

VR-PAT During Home Burn Dressings - Multisite

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-01-16

Completion:

2027-12-01

Conditions

• Burns
• Acute Pain
• Procedural Pain
• Injuries
• Pediatric ALL

Interventions

• OTHER

No Results Yet

NCT05673200 | SUSPENDED | PHASE1

32 participants

Testing the Addition of an Anti-cancer Drug, ASTX727 (Cedazuridine, Decitabine), to Chemotherapy (Paclitaxel) and Immunotherapy (Pembrolizumab) for Metastatic Triple-Negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-09-25

Completion:

2027-02-23

Conditions

• Anatomic Stage III Breast Cancer AJCC v8
• Anatomic Stage IV Breast Cancer AJCC v8
• Metastatic Triple-Negative Breast Carcinoma
• Unresectable Triple-Negative Breast Carcinoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet

NCT05669989 | ENROLLING_BY_INVITATION | PHASE2

70 participants

International Treatment-extension Study in Adult Participants With Multiple Myeloma and Who Have Derived Clinical Benefit From Isatuximab

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-04-05

Completion:

2028-11-30

Conditions

• Plasma Cell Myeloma

Interventions

• DRUG

No Results Yet

NCT05669664 | ACTIVE_NOT_RECRUITING | PHASE2

21 participants

Testing the Anti-cancer Drug Darolutamide in Patients With Testosterone-Driven Salivary Gland Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-07-20

Completion:

2026-11-30

Conditions

• Locally Advanced Salivary Gland Carcinoma
• Metastatic Salivary Gland Carcinoma
• Recurrent Salivary Gland Carcinoma
• Unresectable Salivary Gland Carcinoma

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05663866 | ACTIVE_NOT_RECRUITING | PHASE2

68 participants

Premedication to Reduce Amivantamab Associated Infusion Related Reactions

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-05-18

Completion:

2024-03-29

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DRUG

Results Available

NCT05645224 | ACTIVE_NOT_RECRUITING | NA

40 participants

VR-PAT for Pain and Anxiety Management During Pediatric Dermatologic Laser Procedures

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-01-09

Completion:

2025-11-14

Conditions

• Procedural Anxiety
• Procedural Pain

Interventions

• OTHER

No Results Yet

NCT05625659 | RECRUITING | NA

2032 participants

Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breasts

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-03-24

Completion:

2027-07-31

Conditions

• Breast Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05610059 | COMPLETED | NA

200 participants

Improving Hypertension Medication Adherence for Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-11-02

Completion:

2025-03-14

Conditions

• Aging
• Medication Adherence
• Hypertension

Interventions

• OTHER

Results Available

NCT05609786 | COMPLETED | NA

440 participants

Dissemination and Implementation of a Web-based Relationship Safety App, myPlanKenya, for Women at Risk for Intimate Partner Violence in Nairobi, Kenya

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-06-22

Completion:

2024-12-31

Conditions

• Violence, Domestic
• Violence, Sexual
• Violence, Gender-Based

Interventions

• BEHAVIORAL

Results Available

NCT05589402 | COMPLETED | PHASE1

52 participants

Temporary Inactivation of Strong Muscle Sensation to Improve Rehabilitation Interventions in SCI

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2019-06-04

Completion:

2026-07-15

Conditions

• Spinal Cord Injuries
• Spine Disease
• Stroke

Interventions

• DRUG
• OTHER

No Results Yet

NCT05568264 | ACTIVE_NOT_RECRUITING | NA

222 participants

Effects of a Physical Therapy Intervention on Motor Delay in Infants Admitted to a Neonatal Intensive Care Unit

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-10-01

Completion:

2026-12-31

Conditions

• Motor Delay
• Premature Birth
• Intraventricular Hemorrhage
• Hypoxic-Ischemic Encephalopathy
• Bronchopulmonary Dysplasia

Interventions

• OTHER

No Results Yet

NCT05568095 | ACTIVE_NOT_RECRUITING | PHASE3

1040 participants

A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-11-21

Completion:

2026-08-31

Conditions

• Advanced Upper Gastrointestinal Tract Adenocarcinoma

Interventions

• DRUG

No Results Yet

NCT05567640 | RECRUITING | NA

1800 participants

Using Machine Learning to Optimize User Engagement and Clinical Response to Digital Mental Health Interventions

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-04-12

Completion:

2027-07-31

Conditions

• Anxiety Disorders and Symptoms
• Depressive Symptoms

Interventions

• BEHAVIORAL

No Results Yet

NCT05537857 | ACTIVE_NOT_RECRUITING | NA

66 participants

Racial/Ethnic in Calcium and Sodium Metabolism

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-03-01

Completion:

2026-08-31

Conditions

• Healthy

Interventions

• OTHER

No Results Yet

NCT05524532 | COMPLETED | PHASE3

101 participants

Effects of Immulina TM Supplements With PASC Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-07-20

Completion:

2025-07-29

Conditions

• Post Acute COVID-19 Syndrome

Interventions

• DRUG
• DIETARY_SUPPLEMENT

No Results Yet

NCT05508035 | RECRUITING | PHASE3

488 participants

The Effect of Sacubitril/Valsartan Versus Ramipril on Left Ventricular Function and Remodeling in Patients With Ischemic Heart Failure With Mid-range Ejection Fraction

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-07-13

Completion:

2028-08-31

Conditions

• Heart Failure With Moderately Reduced Ejection Fraction

Interventions

• DRUG

No Results Yet

NCT05488314 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

57 participants

A Study of Amivantamab and Capmatinib Combination Therapy in Unresectable Metastatic Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-12-13

Completion:

2027-04-28

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DRUG

No Results Yet

NCT05438043 | ACTIVE_NOT_RECRUITING | PHASE3

213 participants

A Study of Daratumumab

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-12-15

Completion:

2029-01-31

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT05432284 | NOT_YET_RECRUITING | PHASE1

32 participants

Behavioral Pharmacology of THC and Beta-Myrcene

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2027-07-31

Completion:

2028-11-30

Conditions

• Cannabis Use

Interventions

• DRUG

No Results Yet

NCT05424822 | ACTIVE_NOT_RECRUITING | PHASE1

167 participants

A Study of JNJ-80948543, a T-cell Redirecting CD79b x CD20 x CD3 Trispecific Antibody, in Participants With Non-Hodgkin Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-08-18

Completion:

2025-10-31

Conditions

• Lymphoma, Non-Hodgkin
• Leukemia, Lymphocytic, Chronic, B-Cell

Interventions

• DRUG

No Results Yet

NCT05421663 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

166 participants

A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-08-12

Completion:

2028-12-29

Conditions

• Lymphoma, Non-Hodgkin
• Lymphoma, B-Cell
• Lymphoma, Large B-Cell, Diffuse

Interventions

• BIOLOGICAL

No Results Yet

NCT05393661 | ACTIVE_NOT_RECRUITING

2000 participants

Focused Intensive Repeated Stepping During Inpatient Rehabilitation Poststroke - A Quality Improvement Project

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-31

Start Date:

2017-01-01

Completion:

2030-12-31

Conditions

• Stroke, Acute
• Gait, Hemiplegic

Interventions

• OTHER

No Results Yet

NCT05388669 | ACTIVE_NOT_RECRUITING | PHASE3

418 participants

A Study of Lazertinib With Subcutaneous Amivantamab Compared With Intravenous Amivantamab in Participants With Epidermal Growth Factor Receptor (EGFR)-Mutated Advanced or Metastatic Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-08-05

Completion:

2024-01-03

Conditions

• Advanced or Metastatic Non-small Cell Lung Cancer

Interventions

• DRUG

Results Available

NCT05384561 | RECRUITING | NA

70 participants

Olfactory Training as a Treatment for Olfactory Dysfunction Post COVID-19

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-05-31

Completion:

2027-09-30

Conditions

• Hyposmia
• COVID-19
• Parosmia
• Anosmia
• SARS-CoV-2 Infection

Interventions

• OTHER

No Results Yet

NCT05382559 | RECRUITING | PHASE1

681 participants

A Study of ASP3082 in Adults With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-06-08

Completion:

2028-12-31

Conditions

• Solid Tumor

Interventions

• DRUG

No Results Yet

NCT05372640 | RECRUITING | PHASE1

45 participants

Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-08-10

Completion:

2027-06-07

Conditions

• Anatomic Stage III Breast Cancer AJCC v8
• Anatomic Stage IV Breast Cancer AJCC v8
• Metastatic Breast Carcinoma
• Metastatic Malignant Solid Neoplasm
• Metastatic NUT Carcinoma
• Unresectable Breast Carcinoma
• Unresectable Malignant Solid Neoplasm
• Unresectable NUT Carcinoma

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT05364372 | COMPLETED | NA

187 participants

SMLI With Hispanic Cancer Survivors and Caregivers

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-08-25

Completion:

2026-06-17

Conditions

• Cancer Survivors
• Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT05355701 | RECRUITING | PHASE1

267 participants

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-07-05

Completion:

2028-04-23

Conditions

• Melanoma
• Non-Small-Cell Lung Cancer
• Thyroid Cancer
• Glioma
• Advanced Colorectal Cancer (Part 1)

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT05347095 | ACTIVE_NOT_RECRUITING | PHASE3

288 participants

A Study of Guselkumab in Participants With Fistulizing, Perianal Crohn's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-09-27

Completion:

2027-03-25

Conditions

• Fistulizing Crohns Disease
• Perianal Crohns Disease

Interventions

• DRUG

No Results Yet