Clinical Trials

NCT05189925 | RECRUITING | PHASE1

25 participants

NADPH Oxidase Correction in mRNA-transfected Granulocyte-enriched Cells in Chronic Granulomatous Disease (CGD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-07-22
Completion:: 2027-07-01

Conditions

Chronic Granulomatous Disease
Infection

Interventions

BIOLOGICAL

No Results Yet

NCT05186740 | ACTIVE_NOT_RECRUITING | NA

221 participants

ProVee Urethral Expander System IDE Study (ProVIDE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-06-09
Completion:: 2024-03-15

Conditions

BPH With Symptomatic Lower Urinary Tract Symptoms

Interventions

DEVICE
PROCEDURE

Results Available

NCT05141682 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

11 participants

Oral Azacitidine for the Treatment of Relapsed or Refractory T-cell Large Granular Lymphocytic Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-06-29
Completion:: 2026-02-19

Conditions

T-Cell Large Granular Lymphocyte Leukemia

Interventions

DRUG

No Results Yet

NCT05109468 | ACTIVE_NOT_RECRUITING

46 participants

Assessment of Patients' Quality of Sexual Life After Anal Cancer Treatment

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-06-06
Completion:: 2023-08-31

Conditions

Anal Cancer
Sexuality
Psychologic Stress
HPV
Anxiety

Interventions

OTHER

No Results Yet

NCT05062863 | COMPLETED

139 participants

An Observational Clinical Study of the T3 Dental Implant System

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-10-20
Completion:: 2026-03-03

Conditions

Edentulous Jaw

Interventions

DEVICE

No Results Yet

NCT05050942 | ACTIVE_NOT_RECRUITING | PHASE3

332 participants

A Trial to Assess Efficacy and Safety of Octreotide Subcutaneous Depot in Patients With GEP-NET

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-10-22
Completion:: 2026-11-30

Conditions

Gastro-enteropancreatic Neuroendocrine Tumor

Interventions

DRUG

No Results Yet

NCT05045482 | RECRUITING | PHASE1

30 participants

Hepatic Impairment With Cirrhosis Due to Cholestatic Liver Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-10-21
Completion:: 2026-07-31

Conditions

Hepatic Impairment
Cirrhosis
Cholestatic Liver Disease

Interventions

DRUG

No Results Yet

NCT05044819 | ACTIVE_NOT_RECRUITING | PHASE4

154 participants

Assessment of Potential for Chronic Liver Injury in Participants Treated With Epidiolex (Cannabidiol) Oral Solution

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-07-07
Completion:: 2027-08-01

Conditions

Lennox Gastaut Syndrome
Dravet Syndrome
Tuberous Sclerosis Complex

Interventions

DRUG

No Results Yet

NCT05044546 | ACTIVE_NOT_RECRUITING | NA

26 participants

A Behavioral Activation Prenatal and Postpartum Intervention for Depressed Pregnant Smokers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-10-19
Completion:: 2024-11-22

Conditions

Depression
Tobacco Use Disorder

Interventions

OTHER
BEHAVIORAL
PROCEDURE

Results Available

NCT05021835 | COMPLETED | PHASE3

6385 participants

ZEUS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Cardiovascular Disease, Chronic Kidney Disease and Inflammation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-08-30
Completion:: 2026-06-09

Conditions

Cardiovascular Risk
Chronic Kidney Disease
Inflammation

Interventions

DRUG

No Results Yet

NCT05009069 | ACTIVE_NOT_RECRUITING | PHASE2

58 participants

A Study of Atezolizumab With or Without Tiragolumab Following Neoadjuvant Chemoradiotherapy in Participants With Locally Advanced Rectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-03-18
Completion:: 2023-11-21

Conditions

Rectal Neoplasms
Rectal Cancer

Interventions

DRUG
RADIATION

No Results Yet

NCT04968808 | RECRUITING | NA

1014 participants

Timing of FFR-guided PCI for Non-IRA in NSTEMI and MVD (OPTION-NSTEMI)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-09-06
Completion:: 2028-08-31

Conditions

Myocardial Infarction, Acute
Multi-Vessel Coronary Artery Stenosis
Multi Vessel Coronary Artery Disease

Interventions

PROCEDURE

No Results Yet

NCT04928846 | RECRUITING | PHASE3

768 participants

A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-03-25
Completion:: 2028-12-31

Conditions

Non Small Cell Lung Cancer

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT04905693 | ENROLLING_BY_INVITATION | PHASE3

1850 participants

Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-09-06
Completion:: 2029-12-31

Conditions

Idiopathic Pulmonary Fibrosis
Interstitial Lung Disease
Progressive Pulmonary Fibrosis

Interventions

DRUG
DEVICE

No Results Yet

NCT04855032 | COMPLETED | NA

86 participants

Post-stroke Perturbation Training

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-10-06
Completion:: 2025-11-21

Conditions

Stroke

Interventions

BEHAVIORAL

No Results Yet

NCT04821089 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

727 participants

A Study to Assess the Safety and Efficacy of IPN10200 in Adult Participants With Moderate to Severe Upper Facial Lines

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-04-06
Completion:: 2026-08-31

Conditions

Moderate to Severe Upper Facial Lines

Interventions

BIOLOGICAL

No Results Yet

NCT04798014 | COMPLETED

860 participants

HERO-2: Home-Reported Outcomes With CFTR Modulator Therapy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-05-26
Completion:: 2023-08-15

Conditions

Cystic Fibrosis

No Results Yet

NCT04763200 | ACTIVE_NOT_RECRUITING | NA

1252 participants

Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-04-13
Completion:: 2026-10-31

Conditions

Left Ventricular Dysfunction
Coronary Artery Disease

Interventions

DEVICE

No Results Yet

NCT04752774 | RECRUITING | PHASE1/PHASE2

240 participants

A Study to Assess the Safety and Efficacy of IPN10200 in Adult Participants With Upper Limb Spasticity.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-04-29
Completion:: 2029-03-30

Conditions

Spasticity

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT04743661 | ACTIVE_NOT_RECRUITING | PHASE2

62 participants

131I-Omburtamab, in Recurrent Medulloblastoma and Ependymoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-04-04
Completion:: 2026-04-01

Conditions

Recurrent Medulloblastoma
Recurrent Ependymoma

Interventions

DRUG

No Results Yet

NCT04742894 | RECRUITING | NA

100 participants

Neural Bases of Vocal Sensorimotor Impairment in Aphasia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-07-11
Completion:: 2027-02-28

Conditions

Aphasia

Interventions

BEHAVIORAL

No Results Yet

NCT04734106 | RECRUITING | EARLY_PHASE1

30 participants

Safety and Efficacy of Aloe Vera in the Management of the Symptoms of Interstitial Cystitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2025-02-18
Completion:: 2027-04-30

Conditions

Interstitial Cystitis
Chronic Interstitial Cystitis
Bladder Pain Syndrome

Interventions

DRUG
OTHER

No Results Yet

NCT04713787 | RECRUITING | PHASE2

249 participants

A Safety and Efficacy Study of Different Doses of Oxfendazole Compared to a Single Dose of Albendazole to Treat Trichuris Trichiura Infection in Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2024-09-07
Completion:: 2027-02-28

Conditions

Trichuriasis

Interventions

DRUG

No Results Yet

NCT04644575 | ACTIVE_NOT_RECRUITING | PHASE3

261 participants

Long-term Safety and Efficacy of Efanesoctocog Alfa (BIVV001) in Previously Treated Patients With Hemophilia A

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-02-23
Completion:: 2027-01-15

Conditions

Hemophilia A

Interventions

DRUG

No Results Yet

NCT04603040 | TERMINATED | PHASE2

17 participants

A Study to Evaluate the Efficacy and Safety of Toripalimab Injection in the Treatment of Recurrent or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Who Have Failed at Least Two Prior Lines of Therapy and Are Positive Specific Markers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2020-09-28
Completion:: 2023-03-27

Conditions

Recurrent or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Who Have Failed at Least Two Prior Lines of Therapy

Interventions

DRUG

No Results Yet

NCT04563871 | COMPLETED | PHASE2

73 participants

Efficacy and Safety of 80mg Osimertinib in Patients With Non-small Cell Lung Cancer(NSCLC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2020-11-17
Completion:: 2023-10-25

Conditions

Non-small Cell Lung Cancer (NSCLC)

Interventions

DRUG

No Results Yet

NCT04552171 | COMPLETED | NA

314 participants

Game Plan: Efficacy of a Brief, Web-based Intervention on Alcohol Use and Sexually-transmitted Infections

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-08-13
Completion:: 2025-09-01

Conditions

Sexually Transmitted Diseases, Bacterial
Alcohol; Harmful Use

Interventions

BEHAVIORAL

No Results Yet

NCT04524767 | COMPLETED | NA

505 participants

Depression Screening in Black Churches

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-08-01
Completion:: 2025-07-18

Conditions

Depression

Interventions

BEHAVIORAL

Results Available

NCT04494412 | COMPLETED | PHASE2

8 participants

An Intravenous (IV) Zanamivir Pharmacokinetics (PK) Study in Hospitalized Neonates and Infants With Influenza Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-11-21
Completion:: 2026-01-14

Conditions

Influenza, Human
Arthralgia

Interventions

DRUG

No Results Yet

NCT04484818 | ACTIVE_NOT_RECRUITING | PHASE3

27 participants

Testing the Addition of Darolutamide to Hormonal Therapy (Androgen Deprivation Therapy [ADT]) After Surgery for Men With High-Risk Prostate Cancer, The ERADICATE Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-03-01
Completion:: 2026-06-09

Conditions

Prostate Carcinoma

Interventions

DRUG
OTHER

No Results Yet

NCT04463407 | COMPLETED | NA

36 participants

Effect of a Single Nutritional Intervention Previous to a Critical Period of Fat Gain in University Students With Overweight and Obesity

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2017-08-28
Completion:: 2017-09-27

Conditions

Obesity

Interventions

OTHER

No Results Yet

NCT04436731 | COMPLETED | EARLY_PHASE1

73 participants

Sex Disparities in Hypoxic Sympatholysis and Impact of Obesity

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2020-12-09
Completion:: 2026-07-02

Conditions

Obesity
Healthy
Vasoconstriction
Vasodilation

Interventions

OTHER

No Results Yet

NCT04432584 | ACTIVE_NOT_RECRUITING | PHASE3

190 participants

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Complement Inhibitors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2020-09-30
Completion:: 2027-04-18

Conditions

Paroxysmal Nocturnal Hemoglobinuria

Interventions

DRUG

No Results Yet

NCT04392622 | RECRUITING | PHASE1

40 participants

d-Limonene +Radiation +PlatinumBasedChemo for Xerostomia Prevention in LocallyAdvanced HNSCC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-02-15
Completion:: 2027-08-15

Conditions

Xerostomia

Interventions

DRUG
RADIATION
OTHER

No Results Yet

NCT04318886 | ACTIVE_NOT_RECRUITING | PHASE3

387 participants

Lay Coach-Led Early Palliative Care for Underserved Advanced Cancer Caregivers: The Project ENABLE Cornerstone RCT

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2021-01-07
Completion:: 2025-12-31

Conditions

Cancer Metastatic
Family Members

Interventions

BEHAVIORAL

No Results Yet

NCT04298255 | RECRUITING | NA

50 participants

Experimental Round Spermatid Injection (ROSI) to Treat Infertile Couples

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2020-08-24
Completion:: 2028-07-31

Conditions

Infertility, Male

Interventions

OTHER

No Results Yet

NCT04237545 | COMPLETED | NA

106 participants

A Clinical Study of the T3 Short Dental Implant System

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2019-10-01
Completion:: 2026-01-01

Conditions

Edentulous Jaw

Interventions

DEVICE

No Results Yet

NCT04171999 | COMPLETED | NA

660 participants

CommunityRx-Hunger

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2020-01-06
Completion:: 2023-09-30

Conditions

Food Insecurity

Interventions

OTHER

Results Available

NCT04167514 | COMPLETED | PHASE3

136 participants

Treatment of GVHD in Hematopoietic Stem Cell Transplant (HSCT) Recipients Using AAT Plus Corticosteroids (CS) Compared With Corticosteroids Alone

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2020-01-09
Completion:: 2023-09-11

Conditions

Graft Versus Host Disease (GVHD)

Interventions

BIOLOGICAL
DRUG

Results Available

NCT04162938 | RECRUITING | NA

308 participants

Use of a Patient-Centered Electronic App to Increase ED Patient's Knowledge on HCV to Improve the HCV Care Continuum

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-03-24
Completion:: 2026-09-30

Conditions

Hepatitis C

Interventions

OTHER

No Results Yet