Clinical Trials

NCT04884035 | ACTIVE_NOT_RECRUITING | PHASE1

224 participants

Study of Safety and Efficacy of Iberdomide (CC-220) and CC-99282 Combined With R-CHOP to Treat Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2021-09-15
Completion:: 2028-12-01

Conditions

Lymphoma, B-Cell

Interventions

DRUG

No Results Yet

NCT04852328 | RECRUITING | PHASE2

30 participants

Three Schedules of CUE-101 Administered Before Surgery or Definitive Chemoradiation Therapy in HLA-A*0201 Positive Patients With Locally Advanced, HPV16-Positive Oropharyngeal Squamous-Cell Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2021-12-06
Completion:: 2027-10-31

Conditions

Oropharyngeal Squamous Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT04796818 | RECRUITING | NA

70 participants

An Investigational Scan (Intravoxel Incoherent Motion Diffusion Weighted Imaging) for the Evaluation of Colorectal Cancer Liver Metastases Treatment Response

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2020-08-12
Completion:: 2027-02-02

Conditions

Metastatic Colorectal Carcinoma
Metastatic Malignant Neoplasm in the Liver
Resectable Colorectal Carcinoma
Stage IV Colorectal Cancer AJCC v8
Stage IVA Colorectal Cancer AJCC v8
Stage IVB Colorectal Cancer AJCC v8
Stage IVC Colorectal Cancer AJCC v8

Interventions

PROCEDURE

No Results Yet

NCT04781322 | RECRUITING | PHASE1

100 participants

Safety, Tolerability, and Bioeffects of Alirocumab in Non-treatment Seeking Heavy Drinkers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2021-10-19
Completion:: 2026-12-31

Conditions

Alcohol Associated Liver Disease
Heavy Drinking Behavior

Interventions

DRUG
OTHER

No Results Yet

NCT04758780 | COMPLETED | PHASE2

12 participants

Imaging Performance Assessment of 89Zi-girentuximab (89Zr-TLX250) PET in Metastatic Triple Negative Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2021-09-21
Completion:: 2023-03-31

Conditions

Triple Negative Breast Cancer

Interventions

DRUG

Results Available

NCT04743934 | COMPLETED | PHASE2

44 participants

Flibanserin in Men Receiving Androgen Suppression for Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2021-07-02
Completion:: 2025-03-01

Conditions

Prostate Adenocarcinoma

Interventions

DRUG

Results Available

NCT04706598 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

25 participants

Safety and Efficacy of Camrelizumab for High-risk NMIBC Failing BCG Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2021-06-09
Completion:: 2024-07-11

Conditions

Urinary Bladder Neoplasms
Immunotherapy

Interventions

DRUG

No Results Yet

NCT04703517 | WITHDRAWN | NA

0 participants

Musculoskeletal Ultrasound for Diagnosis of Shoulder Dislocation Reduction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2021-01-01
Completion:: 2021-12-30

Conditions

Ultrasound
Shoulder Dislocation
Musculoskeletal Injury

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04703192 | ACTIVE_NOT_RECRUITING | PHASE2

155 participants

Valemetostat Tosylate (DS-3201b), an Enhancer of Zeste Homolog (EZH) 1/2 Dual Inhibitor, for Relapsed/Refractory Peripheral T-Cell Lymphoma (VALENTINE-PTCL01)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2021-06-03
Completion:: 2023-05-10

Conditions

Relapsed/Refractory Peripheral T-Cell Lymphoma
Adult T Cell Leukemia/Lymphoma

Interventions

DRUG

Results Available

NCT04682600 | COMPLETED | NA

164 participants

The Sonic Incytes Liver Incytes System, Evaluation of Liver Fibrosis and Steatosis Versus MRE and MRI PDFF

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2020-10-21
Completion:: 2022-11-01

Conditions

Non-Alcoholic Fatty Liver Disease (NAFLD)
Non-Alcoholic Steatohepatitis (NASH)
Liver Fibroses
Liver Steatoses

Interventions

DEVICE

No Results Yet

NCT04655755 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

52 participants

Venetoclax in Combination With ASTX727 for the Treatment of Treatment-Naive High-Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2021-01-19
Completion:: 2028-07-20

Conditions

Chronic Myelomonocytic Leukemia
Myelodysplastic Syndrome

Interventions

DRUG

No Results Yet

NCT04652115 | RECRUITING | PHASE2

42 participants

Defibrotide for the Treatment of Severe COVID-19

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2021-01-01
Completion:: 2026-12-24

Conditions

Covid19

Interventions

DRUG

No Results Yet

NCT04600570 | RECRUITING

200 participants

Ultrasonographic Measurement of the Optic Nerve Sheath Diameter in the Taiwanese Healthy Volunteers

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-20
Start Date:: 2020-10-16
Completion:: 2027-10-15

Conditions

Normal Diameter of Optic Nerve

Interventions

OTHER

No Results Yet

NCT04599140 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

51 participants

SX-682 and Nivolumab for the Treatment of RAS-Mutated, MSS Unresectable or Metastatic Colorectal Cancer, the STOPTRAFFIC-1 Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2020-10-14
Completion:: 2026-07-31

Conditions

Metastatic Colon Adenocarcinoma
Metastatic Colorectal Carcinoma
Metastatic Rectal Adenocarcinoma
Stage III Colon Cancer AJCC v8
Stage III Rectal Cancer AJCC v8
Stage IIIA Colon Cancer AJCC v8
Stage IIIA Rectal Cancer AJCC v8
Stage IIIB Colon Cancer AJCC v8
Stage IIIB Rectal Cancer AJCC v8
Stage IIIC Colon Cancer AJCC v8
Stage IIIC Rectal Cancer AJCC v8
Stage IV Colon Cancer AJCC v8
Stage IV Rectal Cancer AJCC v8
Stage IVA Colon Cancer AJCC v8
Stage IVA Rectal Cancer AJCC v8
Stage IVB Colon Cancer AJCC v8
Stage IVB Rectal Cancer AJCC v8
Stage IVC Colon Cancer AJCC v8
Stage IVC Rectal Cancer AJCC v8
Unresectable Colon Adenocarcinoma
Unresectable Rectal Adenocarcinoma

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT04590261 | WITHDRAWN | NA

0 participants

Myeloid Cells in Patients With Covid-19 Pneumonia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2023-09-28
Completion:: 2023-09-28

Conditions

Covid-19; SARS-Cov2

Interventions

OTHER

No Results Yet

NCT04579692 | ACTIVE_NOT_RECRUITING | NA

10 participants

MR Guided Focused Ultrasound (FUS) for the Treatment of Trigeminal Neuralgia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2021-08-16
Completion:: 2026-05-28

Conditions

Trigeminal Neuralgia

Interventions

DEVICE

No Results Yet

NCT04577404 | COMPLETED | PHASE3

124 participants

Safety Extension Study of Oral Edaravone Administered in Subjects With Amyotrophic Lateral Sclerosis (ALS)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2020-10-29
Completion:: 2023-08-09

Conditions

Amyotrophic Lateral Sclerosis (ALS)

Interventions

DRUG

Results Available

NCT04569084 | TERMINATED | PHASE3

384 participants

Efficacy and Safety Study of Oral Edaravone Administered in Subjects With ALS

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2020-11-13
Completion:: 2023-09-29

Conditions

ALS

Interventions

DRUG

Results Available

NCT04559737 | WITHDRAWN | NA

0 participants

CPAP Population Management

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2020-07-31
Completion:: 2020-07-08

Conditions

Obstructive Sleep Apnea (OSA)

Interventions

OTHER

No Results Yet

NCT04550962 | COMPLETED

376 participants

Description of Characteristics, Such as Age, Previous and Concurrent Treatments, Associated Diseases, of Patients With Asthma Treated With Dupilumab (DUPIXENT)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-20
Start Date:: 2020-11-02
Completion:: 2026-06-18

Conditions

Asthma

Interventions

DRUG

No Results Yet

NCT04545957 | RECRUITING | NA

86 participants

Jump: MR Simulation For Radiation Therapy Master Protocol

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2020-10-14
Completion:: 2030-10-22

Conditions

Prostate Cancer
Recurrent Adenocarcinoma
Liver Cancer
Head and Neck Cancer

Interventions

DEVICE
RADIATION

No Results Yet

NCT04520659 | COMPLETED | PHASE1

81 participants

Evaluating the Infectivity, Safety and Immunogenicity of a Recombinant Live-Attenuated Respiratory Syncytial Virus Vaccine, LID/ΔM2-2/1030s, in RSV-Seronegative Infants and Children 6 to 24 Months of Age

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2022-03-16
Completion:: 2024-04-18

Conditions

RSV Infection

Interventions

BIOLOGICAL

Results Available

NCT04489732 | COMPLETED | PHASE1

6 participants

MSC in Patients With Xerostomia Post XRT in Head and Neck Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2022-02-18
Completion:: 2022-11-22

Conditions

Xerostomia Following Radiotherapy

Interventions

BIOLOGICAL

Results Available

NCT04479696 | RECRUITING | NA

117 participants

Customized Neuro-Imaging Referenced Symptom Video for the Reduction of Patient and Caregiver Anxiety Around Radiation Treatment for Brain Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2019-06-05
Completion:: 2027-02-02

Conditions

Glioblastoma
WHO Grade II Glioma
WHO Grade III Glioma

Interventions

OTHER

No Results Yet

NCT04462172 | COMPLETED | NA

290 participants

A Prospective Multicenter Cohort Study About Internal Fixation Using FNS Versus MCS for Femoral Neck Fracture

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2021-10-30
Completion:: 2025-11-23

Conditions

Femoral Neck Fractures

Interventions

DEVICE

Results Available

NCT04437498 | RECRUITING | NA

100 participants

Vagal Nerve Stimulation in mTBI

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2021-02-25
Completion:: 2026-12-10

Conditions

PTSD
mTBI

Interventions

DEVICE

No Results Yet

NCT04430426 | ENROLLING_BY_INVITATION | NA

4 participants

Heterozygous Individuals for AGXT and Kidney Stones

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2027-07-01
Completion:: 2031-08-01

Conditions

Kidney Stone
Urolithiasis, Calcium Oxalate

Interventions

OTHER

No Results Yet

NCT04402346 | COMPLETED | NA

112 participants

Radiofrequency-assisted Transection of the Pancreas vs Stapler

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2021-02-15
Completion:: 2025-03-31

Conditions

Pancreas; Fistula

Interventions

PROCEDURE

No Results Yet

NCT04401267 | COMPLETED | PHASE2

51 participants

Hypertension Intervention to Reduce Osteonecrosis in Children With Acute Lymphoblastic Leukemia/Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2020-10-15
Completion:: 2023-09-25

Conditions

Hypertension
Osteonecrosis
Osteonecrosis Due to Drug

Interventions

DRUG
OTHER

Results Available

NCT04398407 | COMPLETED | NA

122 participants

Testing the Effectiveness of Mainstream Management Tools to Increase Organizational Commitment and Job Satisfaction and Decrease Turnover Among Peer Providers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2021-05-28
Completion:: 2023-11-30

Conditions

Mental Health
Work Related Stress

Interventions

BEHAVIORAL

No Results Yet

NCT04370301 | RECRUITING | PHASE2

20 participants

Reduced Intensity Haploidentical Transplantation for the Treatment of Primary or Secondary Myelofibrosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2021-02-09
Completion:: 2027-04-30

Conditions

Primary Myelofibrosis
Secondary Myelofibrosis

Interventions

DRUG
RADIATION
PROCEDURE
BIOLOGICAL

No Results Yet

NCT04298034 | ACTIVE_NOT_RECRUITING | PHASE3

300 participants

Preeclampsia Postpartum Antihypertensive Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2020-07-17
Completion:: 2025-06-30

Conditions

Preeclampsia
Hypertension in Pregnancy

Interventions

DRUG

No Results Yet

NCT04223934 | COMPLETED | NA

165 participants

Tailored Drug Titration Using Artificial Intelligence

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2020-02-18
Completion:: 2022-12-30

Conditions

Hypertension

Interventions

OTHER

Results Available

NCT04171830 | ENROLLING_BY_INVITATION | NA

3536 participants

Clinical Surveillance Tool to Screen for Unmet Palliative Needs Among Patients in the Final Year of Life

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2019-06-17
Completion:: 2026-12-31

Conditions

Palliative Therapy
Implementation Science
Screening
Terminal Care

Interventions

OTHER

No Results Yet

NCT04164979 | COMPLETED | PHASE2

34 participants

Ph II Study of Cabozantinib With Pembrolizumab in Metastatic Gastric and Gastroesophageal Adenocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2020-02-04
Completion:: 2023-11-25

Conditions

Gastric Adenocarcinoma
GastroEsophageal Cancer

Interventions

DRUG

Results Available

NCT04163614 | RECRUITING | NA

69 participants

Blood Pressure Slopes and Ultrafiltration in Hemodialysis Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2021-02-10
Completion:: 2026-10-01

Conditions

End Stage Renal Disease
Hypertension
Extracellular Volume Overload
Intradialytic Hypotension

Interventions

OTHER

No Results Yet

NCT04139096 | COMPLETED

60 participants

Genetic Susceptibility to Radiation Induced Thyroid Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-20
Start Date:: 2019-09-22
Completion:: 2021-09-22

Conditions

Thyroid Neoplasms
Genetic Susceptibility
Radiation Exposure

No Results Yet

NCT04121858 | COMPLETED | NA

706 participants

Brain Safe: Consumer Intervention to Reduce Exposure to Drugs Linked to Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2019-10-16
Completion:: 2025-02-27

Conditions

Alzheimer Disease
Dementia

Interventions

OTHER

Results Available

NCT04118387 | RECRUITING | PHASE4

200 participants

Central Sleep Apnea : Physiologic Mechanisms to Inform Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2021-01-07
Completion:: 2026-12-31

Conditions

Sleep Disordered Breathing
Able Bodied

Interventions

DRUG

No Results Yet

NCT04092270 | ACTIVE_NOT_RECRUITING | PHASE1

55 participants

A Study Combining the Peposertib (M3814) Pill With Standard Chemotherapy in Patients With Ovarian Cancer With an Expansion in High Grade Serous Ovarian Cancer and Low Grade Serous Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-20
Start Date:: 2020-05-07
Completion:: 2026-02-12

Conditions

Endometrial High Grade Endometrioid Adenocarcinoma
Fallopian Tube Clear Cell Adenocarcinoma
Fallopian Tube Endometrioid Adenocarcinoma
Fallopian Tube High Grade Serous Adenocarcinoma
Fallopian Tube Malignant Mixed Mesodermal (Mullerian) Tumor
Fallopian Tube Mucinous Adenocarcinoma
Fallopian Tube Transitional Cell Carcinoma
Fallopian Tube Undifferentiated Carcinoma
FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma
FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma
Ovarian High Grade Serous Adenocarcinoma
Ovarian Seromucinous Carcinoma
Ovarian Undifferentiated Carcinoma
Platinum-Sensitive Ovarian Carcinoma
Primary Peritoneal Carcinosarcoma
Primary Peritoneal High Grade Serous Adenocarcinoma
Primary Peritoneal Transitional Cell Carcinoma
Primary Peritoneal Undifferentiated Carcinoma
Recurrent Fallopian Tube Carcinoma
Recurrent Low Grade Fallopian Tube Serous Adenocarcinoma
Recurrent Ovarian Carcinoma
Recurrent Ovarian Clear Cell Adenocarcinoma
Recurrent Ovarian Endometrioid Adenocarcinoma
Recurrent Ovarian Low Grade Serous Adenocarcinoma
Recurrent Ovarian Malignant Mixed Mesodermal (Mullerian) Tumor
Recurrent Ovarian Mucinous Adenocarcinoma
Recurrent Ovarian Transitional Cell Carcinoma
Recurrent Primary Peritoneal Carcinoma
Recurrent Primary Peritoneal Low Grade Serous Adenocarcinoma

Interventions

PROCEDURE
DRUG

No Results Yet