Clinical Trials

NCT05329194 | COMPLETED | PHASE4

286 participants

Effectiveness and Safety Study of Tezepelumab in Adults & Adolescent Participants With Severe Asthma in the United States

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2022-04-29

Completion:

2025-10-01

Conditions

• Asthma

Interventions

• DRUG

Results Available

NCT05296798 | ACTIVE_NOT_RECRUITING | PHASE3

922 participants

A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2022-07-18

Completion:

2027-10-31

Conditions

• Locally Advanced or Metastatic Breast Cancer

Interventions

• DRUG

No Results Yet

NCT05289310 | RECRUITING | NA

60 participants

Low Oxygen Exposure and Weight Status

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2023-05-16

Completion:

2026-10-31

Conditions

• Obesity

Interventions

• OTHER

No Results Yet

NCT05282225 | COMPLETED | NA

300 participants

Adaptive Intervention for Adolescents Following Inpatient Psychiatric Care

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2022-11-07

Completion:

2026-01-22

Conditions

• Suicide
• Suicide, Attempted
• Suicidal Ideation
• Self Harm

Interventions

• BEHAVIORAL

No Results Yet

NCT05273554 | ACTIVE_NOT_RECRUITING | PHASE1

15 participants

A Pilot Study to Assess Changes in Tumor Biology Following Second-line Treatment With Pembrolizumab Plus Lenvatinib in Patients With Advanced Pancreatic Ductal Adenocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2022-08-31

Completion:

2027-12-31

Conditions

• Tumor
• Adenocarcinoma

Interventions

• DRUG

No Results Yet

NCT05250492 | COMPLETED | NA

60 participants

Evaluation of Analgesia by PENG Block Versus Intra-Articular Infiltration in Prosthetic Hip Surgery (API)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2022-03-02

Completion:

2022-09-09

Conditions

• Hip Prosthesis
• Analgesia
• PENG Block

Interventions

• PROCEDURE

No Results Yet

NCT05242952 | COMPLETED | NA

78 participants

The LEARN Study for CVD Prevention

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2023-05-10

Completion:

2025-03-31

Conditions

• Cardiovascular Diseases

Interventions

• BEHAVIORAL

Results Available

NCT05239468 | COMPLETED | PHASE2

72 participants

Study of OCA in Combination With BZF Evaluating Efficacy, Safety and Tolerability in Participants With PBC

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2022-03-21

Completion:

2025-09-01

Conditions

• Primary Biliary Cholangitis

Interventions

• DRUG

Results Available

NCT05237466 | COMPLETED | NA

48 participants

Motivational Interviewing to Enhance Behavioral Change in Older Adults With Hoarding Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2022-06-01

Completion:

2025-12-10

Conditions

• Hoarding Disorder

Interventions

• BEHAVIORAL

Results Available

NCT05233618 | ACTIVE_NOT_RECRUITING | PHASE1

44 participants

Study of Tagraxofusp for Post-Transplant Maintenance for Patients With CD 123+ AML, MDS, MF and CMML (HSCT 002)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2022-07-13

Completion:

2026-10-01

Conditions

• Myelofibrosis
• Chronic Myelomonocytic Leukemia
• Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT05232929 | ACTIVE_NOT_RECRUITING | PHASE4

403 participants

Long-term Follow-up Study of Risdiplam in Participants With Spinal Muscular Atrophy (SMA)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2022-03-29

Completion:

2026-12-31

Conditions

• Spinal Muscular Atrophy

Interventions

• DRUG

No Results Yet

NCT05228275 | ACTIVE_NOT_RECRUITING

549 participants

Evaluation of Immunologic Response Following COVID-19 Vaccination in Children, Adolescents, and Young Adults With Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-16

Start Date:

2022-04-08

Completion:

2027-09-30

Conditions

• COVID-19 Infection
• Hematopoietic and Lymphatic System Neoplasm
• Malignant Solid Neoplasm

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT05213936 | RECRUITING | NA

41 participants

Scalp Cooling for Chemotherapy-Induced Alopecia in Patients of Color

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2022-10-24

Completion:

2026-09-30

Conditions

• Alopecia

Interventions

• DEVICE

No Results Yet

NCT05195645 | COMPLETED | PHASE2

21 participants

AbataCept for the Treatment of Immune-cHeckpoint Inhibitors Induced mYocarditiS

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2022-10-27

Completion:

2024-03-05

Conditions

• Myocarditis

Interventions

• DRUG

No Results Yet

NCT05155475 | COMPLETED

20 participants

Endoscopic Ultrasound Evaluation of the Common Bile Duct in Patients With Obstructive Jaundice Due to Bilio-pancreatic Malignancies (ECCO Trial)

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-16

Start Date:

2019-06-04

Completion:

2019-12-04

Conditions

• Obstructive Jaundice
• Bilio-pancreatic Tumor

Interventions

• PROCEDURE

No Results Yet

NCT05150366 | COMPLETED | NA

100 participants

Impact of Percutaneous Closure of the Left Atrial on the Maximum Proto-diastolic Speed of the Mitral Ring Measured by Tissue Doppler (AURIFER)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2021-09-17

Completion:

2025-02-25

Conditions

• Tissue Doppler
• Left Atrial Closure

Interventions

• PROCEDURE

No Results Yet

NCT05150353 | COMPLETED | NA

128 participants

Detection of Amyloid Deposits in the Wrist by MRI With Mapping and High Resolution Sequences in Systemic Amyloidosis (AMYLOCARP)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2020-01-24

Completion:

2022-04-26

Conditions

• Amyloid
• Systemic Amyloidosis

Interventions

• PROCEDURE

No Results Yet

NCT05148286 | RECRUITING | PHASE4

2426 participants

Albumin and Crystalloid Administration in Septic Shock

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2022-01-17

Completion:

2027-09-30

Conditions

• Septic Shock

Interventions

• DRUG

No Results Yet

NCT05146492 | TERMINATED | NA

3 participants

Pericardial Effusion From Acute Myocardial Infarction: Contributing Factors and Prognosis at One Year (EPERICARDIM)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2021-07-19

Completion:

2024-01-31

Conditions

• Acute Myocardial Infarction
• Pericardial Effusion

Interventions

• PROCEDURE

No Results Yet

NCT05145491 | RECRUITING | NA

400 participants

Randomized Trial Comparing Immediate vs. Deferred Surgery for Symptomatic ERM

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2022-02-22

Completion:

2026-12-31

Conditions

• Epiretinal Membrane

Interventions

• PROCEDURE

No Results Yet

NCT05137379 | COMPLETED

200 participants

Evaluation of a Cohort of Patients With Ehlers-Danlos Syndrome Treated With Orthopedic Surgery (SED-eval)

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-16

Start Date:

2021-03-30

Completion:

2021-09-03

Conditions

• Ehlers-Danlos Syndrome

Interventions

• BEHAVIORAL

No Results Yet

NCT05126615 | TERMINATED | NA

10 participants

Contribution of Auriculotherapy in the Management of Mastectomy With Immediate Reconstruction by Latissimus Dorsi Flap (ATMAGD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2019-05-10

Completion:

2021-08-06

Conditions

• Mastectomy
• Auriculotherapy

Interventions

• DRUG
• BEHAVIORAL

No Results Yet

NCT05122858 | COMPLETED | NA

15 participants

EUS-guided Biliary Drainage of First Intent With the Lumen Apposing Metal Stent vs. ERCP in the Management of Malignant Distal Biliary Obstruction (AXIOS-CPRE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2020-11-13

Completion:

2021-05-13

Conditions

• Endoscopic Retrograde Cholangiopancreatography
• Biliary Drainage
• Echography Ultrasound

Interventions

• PROCEDURE

No Results Yet

NCT05121493 | WITHDRAWN | NA

0 participants

Study of Platelet Rich Plasma Drops to Moderate Clinically Significant Dry Eye

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2027-01-01

Completion:

2028-01-15

Conditions

• Dry Eye Syndromes

Interventions

• OTHER

No Results Yet

NCT05114759 | ACTIVE_NOT_RECRUITING | PHASE1

176 participants

A Phase I Clinical Study of SHR-A2009 for Injection in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2022-01-04

Completion:

2026-12-30

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT05111496 | COMPLETED

83 participants

Evaluation of the Radiological Dose Delivered to Risky Interventional Cardiology Patients (Optidose)

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-16

Start Date:

2020-09-24

Completion:

2022-12-16

Conditions

• X-rays; Effects
• Chronic Total Occlusion

Interventions

• RADIATION

No Results Yet

NCT05111470 | COMPLETED | NA

20 participants

Analysis of the Kinematics of the Shoulder Complex in Sports "Overhead" Gestures Such as Kayaking Polo Throwing (Overhead)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2019-10-29

Completion:

2020-10-29

Conditions

• Kayak Polo
• Overhead

Interventions

• OTHER

No Results Yet

NCT05111340 | COMPLETED | NA

525 participants

Securing the Immediate Perioperative Walk: Creating and Validating a Score.

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2018-04-23

Completion:

2021-05-01

Conditions

• Wandering Behavior
• Anesthesia

Interventions

• BEHAVIORAL

No Results Yet

NCT05103852 | COMPLETED | NA

35 participants

Feasibility, Safety and Diagnostic Input of Interventional Cardiac MRI on a Series of 35 Patients With an Indication of Right Cardiac Catheterization.

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2018-12-13

Completion:

2022-03-22

Conditions

• Cardiac MRI
• Right Cardiac Catheterization

Interventions

• PROCEDURE

No Results Yet

NCT05101499 | COMPLETED | NA

54 participants

Study on Akin Osteotomy: Fixation Versus Non-fixation (Fixakin)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2019-03-18

Completion:

2023-11-08

Conditions

• Akin Osteotomy
• Hallux Valgus

Interventions

• PROCEDURE

No Results Yet

NCT05100784 | COMPLETED

826 participants

The Human Sperm Survival Assay (HSSA) as an Internal Quality Control for the IVF Consumables (REPROTOX 2)

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-16

Start Date:

2021-03-10

Completion:

2023-01-16

Conditions

• Human Sperm Survival Assay
• Embryotoxicity
• in Vitro Fertilization

Interventions

• BIOLOGICAL

No Results Yet

NCT05100095 | RECRUITING | PHASE2

52 participants

Hypofractionated Radiation Therapy for Merkel Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2021-12-14

Completion:

2028-09-01

Conditions

• Merkel Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT05094466 | ACTIVE_NOT_RECRUITING | NA

120 participants

Parent and Family Obesity Intervention in Reducing Obesity Risk in Racial Ethnic Minority Families

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2019-07-16

Completion:

2027-02-02

Conditions

• Obesity-Related Malignant Neoplasm

Interventions

• BEHAVIORAL
• OTHER
• PROCEDURE

No Results Yet

NCT05093972 | NOT_YET_RECRUITING | PHASE1

22 participants

Ulonivirine (MK-8507) in Participants With Mild or Moderate Hepatic Impairment (MK-8507-014)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2027-01-22

Completion:

2027-06-29

Conditions

• Hepatic Insufficiency

Interventions

• DRUG

No Results Yet

NCT05092373 | RECRUITING | PHASE1

43 participants

Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2022-04-29

Completion:

2026-09-01

Conditions

• Advanced Breast Carcinoma
• Advanced Endometrial Carcinoma
• Advanced Fallopian Tube Carcinoma
• Advanced Hepatocellular Carcinoma
• Advanced Malignant Abdominal Neoplasm
• Advanced Malignant Female Reproductive System Neoplasm
• Advanced Malignant Thoracic Neoplasm
• Advanced Ovarian Carcinoma
• Advanced Primary Peritoneal Carcinoma
• Advanced Renal Cell Carcinoma
• Anatomic Stage III Breast Cancer AJCC v8
• Anatomic Stage IIIA Breast Cancer AJCC v8
• Anatomic Stage IIIB Breast Cancer AJCC v8
• Anatomic Stage IIIC Breast Cancer AJCC v8
• Anatomic Stage IV Breast Cancer AJCC v8
• Malignant Abdominal Neoplasm
• Malignant Solid Neoplasm
• Metastatic Breast Carcinoma
• Metastatic Endometrial Carcinoma
• Metastatic Fallopian Tube Carcinoma
• Metastatic Hepatocellular Carcinoma
• Metastatic Malignant Abdominal Neoplasm
• Metastatic Malignant Female Reproductive System Neoplasm
• Metastatic Malignant Thoracic Neoplasm
• Metastatic Ovarian Carcinoma
• Metastatic Primary Peritoneal Carcinoma
• Metastatic Renal Cell Carcinoma
• Prognostic Stage III Breast Cancer AJCC v8
• Prognostic Stage IIIA Breast Cancer AJCC v8
• Prognostic Stage IIIB Breast Cancer AJCC v8
• Prognostic Stage IIIC Breast Cancer AJCC v8
• Prognostic Stage IV Breast Cancer AJCC v8
• Stage III Fallopian Tube Cancer AJCC v8
• Stage III Hepatocellular Carcinoma AJCC v8
• Stage III Ovarian Cancer AJCC v8
• Stage III Primary Peritoneal Cancer AJCC v8
• Stage III Renal Cell Cancer AJCC v8
• Stage III Uterine Corpus Cancer AJCC v8
• Stage IIIA Fallopian Tube Cancer AJCC v8
• Stage IIIA Hepatocellular Carcinoma AJCC v8
• Stage IIIA Ovarian Cancer AJCC v8
• Stage IIIA Primary Peritoneal Cancer AJCC v8
• Stage IIIA Uterine Corpus Cancer AJCC v8
• Stage IIIA1 Fallopian Tube Cancer AJCC v8
• Stage IIIA1 Ovarian Cancer AJCC v8
• Stage IIIA2 Fallopian Tube Cancer AJCC v8
• Stage IIIA2 Ovarian Cancer AJCC v8
• Stage IIIB Fallopian Tube Cancer AJCC v8
• Stage IIIB Hepatocellular Carcinoma AJCC v8
• Stage IIIB Ovarian Cancer AJCC v8
• Stage IIIB Primary Peritoneal Cancer AJCC v8
• Stage IIIB Uterine Corpus Cancer AJCC v8
• Stage IIIC Fallopian Tube Cancer AJCC v8
• Stage IIIC Ovarian Cancer AJCC v8
• Stage IIIC Primary Peritoneal Cancer AJCC v8
• Stage IIIC Uterine Corpus Cancer AJCC v8
• Stage IIIC1 Uterine Corpus Cancer AJCC v8
• Stage IIIC2 Uterine Corpus Cancer AJCC v8
• Stage IV Fallopian Tube Cancer AJCC v8
• Stage IV Hepatocellular Carcinoma AJCC v8
• Stage IV Ovarian Cancer AJCC v8
• Stage IV Primary Peritoneal Cancer AJCC v8
• Stage IV Renal Cell Cancer AJCC v8
• Stage IV Uterine Corpus Cancer AJCC v8
• Stage IVA Fallopian Tube Cancer AJCC v8
• Stage IVA Hepatocellular Carcinoma AJCC v8
• Stage IVA Ovarian Cancer AJCC v8
• Stage IVA Primary Peritoneal Cancer AJCC v8
• Stage IVA Uterine Corpus Cancer AJCC v8
• Stage IVB Fallopian Tube Cancer AJCC v8
• Stage IVB Hepatocellular Carcinoma AJCC v8
• Stage IVB Ovarian Cancer AJCC v8
• Stage IVB Primary Peritoneal Cancer AJCC v8
• Stage IVB Uterine Corpus Cancer AJCC v8

Interventions

• BIOLOGICAL
• DRUG
• PROCEDURE

No Results Yet

NCT05086445 | COMPLETED | PHASE1

62 participants

A Study of LY3502970 in Japanese Participants With Type 2 Diabetes Mellitus

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2021-11-12

Completion:

2022-09-05

Conditions

• Diabetes Mellitus, Type 2

Interventions

• DRUG

Results Available

NCT05075980 | ACTIVE_NOT_RECRUITING | PHASE2

174 participants

Intensity Modulated Proton or X-Ray Therapy After Surgery for Treatment of Head and Neck Cancer, the HEADLIGHT Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2022-02-16

Completion:

2028-02-05

Conditions

• Head and Neck Carcinoma
• Head and Neck Carcinoma of Unknown Primary
• Hypopharyngeal Carcinoma
• Laryngeal Carcinoma
• Metastatic Malignant Neoplasm in the Lymph Nodes
• Nasal Cavity Carcinoma
• Oral Cavity Carcinoma
• Oropharyngeal Carcinoma
• Paranasal Sinus Carcinoma
• Salivary Gland Carcinoma
• Cutaneous Squamous Cell Carcinoma of the Head and Neck
• Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck

Interventions

• DRUG
• PROCEDURE
• OTHER
• RADIATION

No Results Yet

NCT05053867 | RECRUITING | PHASE3

60 participants

A Randomized Controlled Trial of Inhaled Tranexamic Acid for the Treatment of Pulmonary Hemorrhage in Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2022-10-14

Completion:

2027-07-31

Conditions

• Pulmonary Hemorrhage
• Cancer

Interventions

• DRUG
• OTHER

No Results Yet

NCT05041153 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

15 participants

Pembrolizumab and Lenvatinib for the Treatment of Advanced, Unresectable, or Metastatic Gastroesophageal Adenocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2022-02-14

Completion:

2026-12-30

Conditions

• Advanced Gastric Adenocarcinoma
• Advanced Gastroesophageal Junction Adenocarcinoma
• Clinical Stage III Gastric Cancer AJCC v8
• Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage IV Gastric Cancer AJCC v8
• Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage IVA Gastric Cancer AJCC v8
• Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage IVB Gastric Cancer AJCC v8
• Clinical Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Metastatic Gastric Adenocarcinoma
• Metastatic Gastroesophageal Junction Adenocarcinoma
• Pathologic Stage III Gastric Cancer AJCC v8
• Pathologic Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IIIA Gastric Cancer AJCC v8
• Pathologic Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IIIB Gastric Cancer AJCC v8
• Pathologic Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IIIC Gastric Cancer AJCC v8
• Pathologic Stage IV Gastric Cancer AJCC v8
• Pathologic Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Postneoadjuvant Therapy Stage III Gastric Cancer AJCC v8
• Postneoadjuvant Therapy Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
• Postneoadjuvant Therapy Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Postneoadjuvant Therapy Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8
• Postneoadjuvant Therapy Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
• Postneoadjuvant Therapy Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Postneoadjuvant Therapy Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Unresectable Gastric Adenocarcinoma
• Unresectable Gastroesophageal Junction Adenocarcinoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT05038852 | ACTIVE_NOT_RECRUITING | NA

8 participants

Acceptability of Mobile Applications (Apps) to Enhance Smoking Cessation in a Clinical Tobacco Treatment Program - A Pilot Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-16

Start Date:

2019-04-12

Completion:

2027-02-02

Conditions

• Smoking Cessation
• Tobacco

Interventions

• DEVICE

No Results Yet