Clinical Trials

NCT06742281 | COMPLETED | PHASE2

432 participants

A Phase 2b, Randomized, Double-blind, Active-controlled Study of Single Dose CVXGA Intranasal COVID-19 Vaccine in Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2024-12-05
Completion:: 2026-06-15

Conditions

COVID-19

Interventions

BIOLOGICAL

No Results Yet

NCT06716424 | COMPLETED | PHASE4

105 participants

A Study to Investigate Safety and Efficacy of iGlarLixi in Adult Patients With Type 2 Diabetes Mellitus

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2025-01-06
Completion:: 2026-06-12

Conditions

Type 2 Diabetes

Interventions

DRUG

No Results Yet

NCT06712875 | RECRUITING | PHASE1/PHASE2

27 participants

MAPK Inhibition Combined With Anti-PD1 Therapy for BRAF-altered Pediatric Gliomas

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2025-04-01
Completion:: 2028-12-31

Conditions

Low Grade Glioma
High Grade Glioma

Interventions

DRUG

No Results Yet

NCT06704100 | NOT_YET_RECRUITING | PHASE2

60 participants

Oral Fosamprenavir + Sodium Alginate for GERD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2027-01-01
Completion:: 2028-12-31

Conditions

Refractory Gastroesophageal Reflux Disease
Gastroesophageal Reflux Disease

Interventions

DRUG
OTHER

No Results Yet

NCT06698146 | RECRUITING

80 participants

Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-10
Start Date:: 2025-08-27
Completion:: 2034-01-01

Conditions

Liver Transplant Surgery
Colorectal Cancer Metastatic
Colon Cancer Liver Metastases

No Results Yet

NCT06695845 | RECRUITING | PHASE2

200 participants

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2025-01-14
Completion:: 2026-12-31

Conditions

Breast Cancer
Gastric Cancer
Esophageal Cancer
Gastroesophageal Cancer
Colorectal Cancer
Endometrial Cancer
Non-small Cell Lung Cancer
Ovarian Cancer
Urothelial Carcinoma
Salivary Gland Cancer
Pancreatic Cancer
HER-2 Protein Overexpression

Interventions

DRUG

No Results Yet

NCT06692400 | RECRUITING | NA

110 participants

The Effects of Endotracheal Suctioning on Pain and Serum Markers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2025-01-30
Completion:: 2026-12-31

Conditions

Intensive Care Unit ICU
Intubation
Critical Illness
Mechanical Ventilation
Pain Measurement
Pain, Procedural
Oxidative Stress
Hypoxia
Biomarkers / Blood
Adult
Uric Acid
Sepsis
COVID
Influenza
Pneumonia

Interventions

PROCEDURE

No Results Yet

NCT06681766 | TERMINATED | PHASE1

18 participants

A Study to Assess Nomlabofusp in Adolescents and Children With Friedreich's Ataxia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2024-12-06
Completion:: 2025-04-27

Conditions

Friedreich Ataxia

Interventions

DRUG

No Results Yet

NCT06678555 | COMPLETED

22 participants

A Study to Learn About Lorlatinib in Patients With Non-Small Cell Lung Cancer (NSCLC) Which Has Spread Out.

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-10
Start Date:: 2025-07-04
Completion:: 2026-04-14

Conditions

Carcinoma, Non-Small-Cell Lung

Interventions

DRUG

No Results Yet

NCT06670196 | ACTIVE_NOT_RECRUITING | PHASE3

420 participants

A Study of SKB264 in Combination With Osimertinib Versus Osimertinib in Patients With Epidermal Growth Factor Receptor (EGFR) Mutations, Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2024-11-27
Completion:: 2027-05-31

Conditions

Non-Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT06663761 | COMPLETED | NA

51 participants

Correlation of Pain Intensity Measurements in Healthy Volunteers Exposed to Unpleasant Stimuli

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2024-07-22
Completion:: 2025-11-30

Conditions

Pain

Interventions

BEHAVIORAL

No Results Yet

NCT06643988 | RECRUITING | NA

30 participants

Autobiographical Memory in Opioid Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2025-08-19
Completion:: 2027-01-31

Conditions

Opioid Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06629662 | COMPLETED | NA

66 participants

Robotic Versus Laparoscopic Sleeve Gastrectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2024-10-01
Completion:: 2026-07-01

Conditions

Robotic Surgery

Interventions

PROCEDURE

No Results Yet

NCT06628687 | RECRUITING

10 participants

A Study to Learn How BIIB141 (Omaveloxolone) Affects the Health of Participants With Friedrich's Ataxia Who Took it During Pregnancy and/or During Breastfeeding and About the Health of Their Babies

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-10
Start Date:: 2026-10-26
Completion:: 2035-04-30

Conditions

Friedreich Ataxia

Interventions

DRUG

No Results Yet

NCT06626685 | RECRUITING

300 participants

Clonal Hematopoiesis of Indeterminate Potential in Heart Failure.

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-10
Start Date:: 2025-03-10
Completion:: 2027-08-31

Conditions

Heart Failure

Interventions

OTHER

No Results Yet

NCT06608264 | COMPLETED | NA

78 participants

Stress Ball and Hand Holding on Pain After Knee Arthroplasty

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2024-10-03
Completion:: 2025-07-09

Conditions

Pain and Mobility Levels of Patients Undergoing Total Knee Prosthesis During Continuous Passive Motion Exercise
Total Knee ArthroplastyKnee Pain, Functionality

Interventions

BEHAVIORAL

No Results Yet

NCT06592040 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated:: 2026-07-10

No Results Yet

NCT06591117 | RECRUITING | NA

50 participants

The Vizio Clinical Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2026-03-21
Completion:: 2028-01-31

Conditions

Refractory Glaucoma

Interventions

DEVICE

No Results Yet

NCT06582810 | RECRUITING

20 participants

Lidocaine Infusion Treatment for Subarachnoid Hemorrhage Headaches

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-10
Start Date:: 2025-01-31
Completion:: 2027-10-31

Conditions

Subarachnoid; Hemorrhage, Nontraumatic
Headache

No Results Yet

NCT06579183 | NOT_YET_RECRUITING | NA

60 participants

Pilot Trial for Health Products on Mood and Sleep Quality

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2026-09-30
Completion:: 2027-09-30

Conditions

Sleep Disturbance
Emotional Disturbance

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06568042 | COMPLETED | PHASE2

558 participants

Effects of LY3848575 Versus Placebo in Participants With Painful Distal Sensory Polyneuropathy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2024-08-22
Completion:: 2026-01-12

Conditions

Neuropathic Pain
Distal Sensory Polyneuropathy

Interventions

DRUG

No Results Yet

NCT06562608 | RECRUITING | PHASE4

105 participants

Anticholinergic Deprescription in Schizophrenia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2025-02-01
Completion:: 2028-12-31

Conditions

Schizophrenia
Schizoaffective Disorder

Interventions

DRUG

No Results Yet

NCT06560476 | ACTIVE_NOT_RECRUITING

500 participants

OPtilume™ BPH Catheter SystEm for Treatment of Men eXperiencing Symptomatic BPH

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-10
Start Date:: 2024-03-30
Completion:: 2027-03-30

Conditions

Benign Prostatic Hyperplasia

Interventions

OTHER

No Results Yet

NCT06560242 | RECRUITING | NA

30 participants

Tracking Early Emergence of Sound Perception Impairments in FXS With Multimodal fNIRS/EEG- Infant

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2022-10-31
Completion:: 2027-03-01

Conditions

Fragile X Syndrome

Interventions

OTHER

No Results Yet

NCT06558604 | RECRUITING | PHASE2

100 participants

Phase II Study of Glofitamab With Venetoclax +/- Zanubrutinib in High-risk Mantle-cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2025-02-21
Completion:: 2028-05-31

Conditions

Lymphoma, Mantle-Cell

Interventions

DRUG

No Results Yet

NCT06550362 | NOT_YET_RECRUITING | PHASE4

100 participants

Daily Iron vs Every-other-day Iron for Pediatric Patients With IDA

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2026-12-31
Completion:: 2027-05-31

Conditions

Iron Deficiency Anemia

Interventions

DRUG

No Results Yet

NCT06547658 | COMPLETED | NA

66 participants

The Effect of Mouth Closure on Airflow in OSA

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2021-12-17
Completion:: 2022-07-10

Conditions

Hypopnea, Sleep

Interventions

OTHER

No Results Yet

NCT06544330 | ACTIVE_NOT_RECRUITING | PHASE1

48 participants

A Phase 1 Study of SYNCAR-001 + STK-009 Without Conditioning Chemotherapy (Lymphodepletion) in Subjects With Severe, Refractory Systemic Autoimmune Rheumatic Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2025-04-29
Completion:: 2028-04-30

Conditions

Systemic Lupus Erythematosus
Lupus Nephritis
Systemic Sclerosis

Interventions

DRUG

No Results Yet

NCT06544213 | COMPLETED | NA

24 participants

A 60 Days Head Down Tilt Bedrest With Artificial Gravity and Cycling Exercise on 24 Healthy Male (BRACE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2023-02-06
Completion:: 2024-04-20

Conditions

Simulated Microgravity by Head Down Tilt Bedrest
Weightlessness

Interventions

BEHAVIORAL

No Results Yet

NCT06534905 | COMPLETED | NA

36 participants

E-cigarette Switching Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2024-11-25
Completion:: 2025-10-09

Conditions

Tobacco Use
Opioid Use Disorder
Tobacco-Related Disorders

Interventions

OTHER
BEHAVIORAL

No Results Yet

NCT06525818 | RECRUITING | NA

40 participants

Let's E.A.T.! (Eating With Assistive Technology): An Intervention to Support Children With Feeding Tubes and Tracheostomies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2024-07-08
Completion:: 2027-07-07

Conditions

Feeding Tube
Children With Medical Complexity
Tracheostomy
Feeding Disorder, Infancy or Early Childhood

Interventions

OTHER

No Results Yet

NCT06516900 | COMPLETED | NA

50 participants

Reducing Foot Pain and Peak Plantar Pressure in Patients With Foot Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2024-06-05
Completion:: 2026-04-30

Conditions

Foot Pain

Interventions

DEVICE

No Results Yet

NCT06511908 | RECRUITING | PHASE2

50 participants

Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2024-11-06
Completion:: 2027-07-01

Conditions

Suicide
Depressive Disorder, Treatment-Resistant
Ketamine
Molecular Mechanisms of Pharmacological Action
Neurotransmitter Agents
Excitatory Amino Acid Agents
Physiological Effects of Drugs
Depressive Disorder, Major
Depressive Disorder
Depression
Mental Disorders
Mood Disorders
Behavioral Symptoms

Interventions

DRUG

No Results Yet

NCT06508983 | RECRUITING | PHASE3

360 participants

A Clinical Study Comparing SG301 Plus Pomalidomide and Dexamethasone to Placebo Plus Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2024-06-14
Completion:: 2027-03-31

Conditions

Relapsed/Refractory Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT06470763 | COMPLETED | PHASE1/PHASE2

63 participants

A Study Evaluating ANV600 Single Agent or in Combination With Pembrolizumab in Participants With Advanced Solid Tumors (EXPAND-1)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2024-07-01
Completion:: 2026-06-22

Conditions

Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT06466434 | RECRUITING | PHASE2

75 participants

Prebiotic Food-enriched Diet (PreFED) to Enhance the Microbiome and Response to First-line Immunotherapy in Unresectable Melanoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2024-09-01
Completion:: 2028-06-30

Conditions

Unresectable Melanoma

Interventions

OTHER

No Results Yet

NCT06464549 | COMPLETED

44 participants

Spontaneous Eye Blinking Evaluation for Cognitive Assessment of Individuals With Severe Acquired Brain Injury

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-10
Start Date:: 2025-01-13
Completion:: 2025-11-10

Conditions

Disorders of Consciousness
Acquired Brain Injury

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06454721 | COMPLETED | PHASE1

5 participants

A Study to Determine the Biodistribution, Safety, and Tolerability of a Microdose of Radiolabeled Diranersen (BIIB080) Co-administered With Diranersen in Healthy Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2025-01-30
Completion:: 2026-03-05

Conditions

Healthy Volunteer

Interventions

DRUG

No Results Yet

NCT06450158 | RECRUITING | NA

80 participants

Robot-assisted Training in Children With CP

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2021-09-25
Completion:: 2029-08-31

Conditions

Cerebral Palsy

Interventions

DEVICE

No Results Yet

NCT06446661 | RECRUITING | NA

48 participants

Using Text Messages to Improve Oral Chemotherapy for Adolescents and Adults With Acute Lymphoblastic Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-10
Start Date:: 2026-05-19
Completion:: 2027-06-15

Conditions

Acute Lymphoblastic Leukemia
T-cell Lymphoblastic Lymphoma

Interventions

OTHER

No Results Yet