Clinical Trials

NCT04185363 | COMPLETED | PHASE3

84 participants

An Extension Study of Maralixibat in Patients With Progressive Familial Intrahepatic Cholestasis (PFIC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-01-08

Completion:

2025-04-23

Conditions

• Progressive Familial Intrahepatic Cholestasis (PFIC)

Interventions

• DRUG

Results Available

NCT04154891 | COMPLETED | NA

3825 participants

Genome Sequencing Strategies for Genetics Diagnosis of Patients With Intellectual Disability

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-03-13

Completion:

2023-12-31

Conditions

• Intellectual Disability

Interventions

• GENETIC

No Results Yet

NCT04150640 | RECRUITING | PHASE2

52 participants

Oxaliplatin and Liposomal Irinotecan (Plus Trastuzumab for HER2-positive Disease) in Advanced Esophageal and Gastric Adenocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-07-13

Completion:

2027-12-31

Conditions

• Esophageal Adenocarcinoma
• Gastric Adenocarcinoma

Interventions

• DRUG

No Results Yet

NCT04134754 | RECRUITING | NA

335 participants

Carbon Dioxide (CO2) Chemosensitivity and SUDEP

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-12-12

Completion:

2029-10-01

Conditions

• Epilepsy
• SUDEP

Interventions

• OTHER

No Results Yet

NCT04123366 | COMPLETED | PHASE2

333 participants

Study of Olaparib (MK-7339) in Combination With Pembrolizumab (MK-3475) in the Treatment of Homologous Recombination Repair Mutation (HRRm) and/or Homologous Recombination Deficiency (HRD)-Positive Advanced Cancer (MK-7339-007/KEYLYNK-007)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-11-18

Completion:

2026-06-08

Conditions

• Solid Tumors

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04114136 | RECRUITING | PHASE2

72 participants

Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-09-14

Completion:

2032-04-30

Conditions

• Melanoma
• NSCLC
• Hepatocellular Carcinoma
• Urothelial Cancer
• Gastric Adenocarcinoma
• HNSCC
• Esophageal Adenocarcinoma
• Microsatellite Instability-High Solid Malignant Tumor

Interventions

• DRUG

No Results Yet

NCT04113187 | TERMINATED | PHASE3

15 participants

Propranolol for Epistaxis in Hereditary Hemorrhagic Telangiectasia Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-06-23

Completion:

2022-05-19

Conditions

• Hereditary Hemorrhagic Telangiectasia
• Osler Weber Rendu Disease

Interventions

• DRUG

No Results Yet

NCT04111770 | COMPLETED | NA

806 participants

The OPTIMAL Randomized Controlled Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-07-08

Completion:

2025-07-31

Conditions

• Left Main Coronary Artery Stenosis

Interventions

• DEVICE

No Results Yet

NCT04096170 | COMPLETED | PHASE4

16 participants

Improving Pain Control in Paraesophageal Hernia Repair: Intravenous Lidocaine Versus Placebo

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2018-06-21

Completion:

2024-04-24

Conditions

• Hernia, Paraesophageal

Interventions

• DRUG

Results Available

NCT04084717 | COMPLETED | PHASE2

33 participants

Study of Crizotinib for ROS1 and MET Activated Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-12-03

Completion:

2024-12-30

Conditions

• Non-squamous Non-small-cell Lung Cancer
• Stage IV Non-small Cell Lung Cancer
• ROS1 Gene Rearrangement
• MET Activating Mutation
• MET Amplification

Interventions

• DRUG

No Results Yet

NCT04080804 | ACTIVE_NOT_RECRUITING | PHASE2

80 participants

Study of Safety and Tolerability of Nivolumab Treatment Alone or in Combination With Relatlimab or Ipilimumab in Head and Neck Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-12-20

Completion:

2027-10-01

Conditions

• Head and Neck Squamous Cell Carcinoma (HNSCC)

Interventions

• DRUG

No Results Yet

NCT04067973 | COMPLETED

88 participants

Impact of Prematurity on the Optic Nerve

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-23

Start Date:

2019-09-09

Completion:

2019-12-10

Conditions

• Ocular Surface Disease
• Premature

No Results Yet

NCT04067908 | TERMINATED | NA

111 participants

New Biomarkers Associated With the Risk of Premature Delivery.

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2011-06-07

Completion:

2013-12-28

Conditions

• Premature Delivery

Interventions

• OTHER

No Results Yet

NCT04056117 | COMPLETED | PHASE1/PHASE2

597 participants

A Study to Determine If a New Shigella Vaccine is Safe, Induces Immunity and The Best Dose Among Kenyan Infants

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-09-02

Completion:

2022-09-01

Conditions

• Shigellosis

Interventions

• BIOLOGICAL

No Results Yet

NCT04021719 | SUSPENDED

2100 participants

OnTrackNY's Learning Healthcare System

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-23

Start Date:

2019-08-15

Completion:

2026-12-30

Conditions

• First Episode Psychosis

Interventions

• OTHER

No Results Yet

NCT03991832 | ACTIVE_NOT_RECRUITING | PHASE2

58 participants

Study of Olaparib and Durvalumab in IDH-Mutated Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-12-31

Completion:

2026-09-30

Conditions

• Glioma
• Cholangiocarcinoma
• Solid Tumor
• IDH Mutation

Interventions

• DRUG

No Results Yet

NCT03991819 | ACTIVE_NOT_RECRUITING | PHASE1

40 participants

Study of Binimetinib in Combination With Pembrolizumab in Advanced Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-09-20

Completion:

2026-08-31

Conditions

• Non-small Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT03901963 | COMPLETED | PHASE3

200 participants

A Study of Daratumumab Plus Lenalidomide Versus Lenalidomide Alone as Maintenance Treatment in Participants With Newly Diagnosed Multiple Myeloma Who Are Minimal Residual Disease Positive After Frontline Autologous Stem Cell Transplant

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-04-26

Completion:

2024-04-04

Conditions

• Multiple Myeloma

Interventions

• DRUG

Results Available

NCT03896620 | ACTIVE_NOT_RECRUITING

45 participants

Recognition of Circulating Tumor DNA in Soft Tissue Sarcoma

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-23

Start Date:

2019-06-18

Completion:

2027-04-01

Conditions

• Sarcoma

Interventions

• DEVICE
• DRUG
• OTHER

No Results Yet

NCT03872947 | ACTIVE_NOT_RECRUITING | PHASE1

138 participants

A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-04-26

Completion:

2026-06-30

Conditions

• Melanoma
• Solid Tumor
• Colorectal Cancer
• Cholangiocarcinoma
• Bladder Cancer
• Ovarian Cancer
• Gastric Cancer
• Palpable Subcutaneous Malignant Lesions
• Renal Cell Carcinoma
• Epithelial Ovarian Cancer
• Primary Peritoneal Cancer
• Fallopian Tube Cancer

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT03872180 | ACTIVE_NOT_RECRUITING | PHASE2

23 participants

Bendamustine, Obinutuzumab, and Venetoclax in Patients With Untreated Mantle Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-04-11

Completion:

2022-06-06

Conditions

• CCND1 Positive
• Mantle Cell Lymphoma
• t(11;14) Positive

Interventions

• DRUG
• BIOLOGICAL

Results Available

NCT03818412 | RECRUITING | NA

40 participants

Circulating Tumor DNA in Soft Tissue Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-01-17

Completion:

2026-12-17

Conditions

• Soft Tissue Sarcoma

Interventions

• PROCEDURE

No Results Yet

NCT03810612 | ACTIVE_NOT_RECRUITING

3417 participants

Patient-reported Outcomes After Percutaneous Coronary Intervention

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-23

Start Date:

2017-06-12

Completion:

2030-05-31

Conditions

• Coronary Artery Disease

No Results Yet

NCT03810599 | ACTIVE_NOT_RECRUITING | NA

870 participants

Patient-reported Outcomes in the Bergen Early Cardiac Rehabilitation Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2013-09-09

Completion:

2019-06-27

Conditions

• Coronary Artery Disease

Interventions

• OTHER

No Results Yet

NCT03808922 | RECRUITING | PHASE3

274 participants

Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-05-23

Completion:

2028-09-01

Conditions

• Lower Respiratory Tract Infection
• Parainfluenza
• Immunocompromised
• COVID-19

Interventions

• DRUG

No Results Yet

NCT03776513 | TERMINATED | NA

30 participants

Neuro-cognitive Impact of Juvenile Obesity

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2018-12-12

Completion:

2020-02-19

Conditions

• Pediatric Obesity
• Behavior and Behavior Mechanisms
• Emotions

Interventions

• BEHAVIORAL

No Results Yet

NCT03759288 | TERMINATED | PHASE2/PHASE3

89 participants

An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2018-12-07

Completion:

2023-10-18

Conditions

• Crohn's Disease
• IBD

Interventions

• DRUG

Results Available

NCT03752775 | RECRUITING | NA

45 participants

Exoneuromusculoskeleton for Upper Limb Rehabilitation After Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2018-11-01

Completion:

2027-12-31

Conditions

• Upper Limb Rehabilitation

Interventions

• DEVICE

No Results Yet

NCT03748446 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

20 participants

Xenon Inhalation Therapy for Major Depressive Disorder and Bipolar Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-12-05

Completion:

2026-09-01

Conditions

• Major Depressive Disorder
• Bipolar Depression

Interventions

• DRUG

No Results Yet

NCT03717896 | COMPLETED | PHASE2

102 participants

Thiamine as Adjunctive Therapy for Diabetic Ketoacidosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2018-11-21

Completion:

2024-09-30

Conditions

• Diabetic Ketoacidosis

Interventions

• DRUG

Results Available

NCT03709758 | ACTIVE_NOT_RECRUITING | PHASE1

50 participants

Venetoclax in Combination With Intensive Induction and Consolidation Chemotherapy in Treatment Naïve AML

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2018-10-17

Completion:

2025-02-23

Conditions

• Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT03697408 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

23 participants

Itacitinib + Everolimus in Hodgkin Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-02-11

Completion:

2024-05-20

Conditions

• Classical Hodgkin Lymphoma

Interventions

• DRUG

Results Available

NCT03645447 | SUSPENDED | NA

240 participants

The Taste-Mood Diagnostic Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-06-06

Completion:

2026-12-31

Conditions

• Depression

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03641235 | COMPLETED

29 participants

Analysis of the Dynamics of the Lung Microbiota During Acute Exacerbation of COPD Requiring Admission to Intensive Care Unit

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-23

Start Date:

2018-09-01

Completion:

2020-03-02

Conditions

• Chronic Obstructive Pulmonary Disease

Interventions

• BIOLOGICAL

No Results Yet

NCT03616821 | TERMINATED | PHASE2

242 participants

Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2018-08-07

Completion:

2023-10-23

Conditions

• Ulcerative Colitis
• IBD

Interventions

• DRUG

Results Available

NCT03605901 | TERMINATED | PHASE2

21 participants

Dosing of Methadone for Spine Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-03-19

Completion:

2025-05-09

Conditions

• Pain, Postoperative

Interventions

• DRUG

Results Available

NCT03568994 | COMPLETED | EARLY_PHASE1

26 participants

Atovaquone (Mepron®) Combined With Conventional Chemotherapy for de Novo Acute Myeloid Leukemia (AML)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2018-07-10

Completion:

2020-09-29

Conditions

• Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT03536793 | RECRUITING

180 participants

Tumour Regulatory Molecules in Early Pancreatic Cancer Detection

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-23

Start Date:

2018-10-24

Completion:

2027-02-28

Conditions

• Cancer of Pancreas
• Pancreas Cyst

No Results Yet

NCT03529422 | ACTIVE_NOT_RECRUITING | PHASE2

18 participants

Durvalumab With Radiotherapy for Adjuvant Treatment of Intermediate Risk SCCHN

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-10-07

Completion:

2024-07-01

Conditions

• Larynx
• Lip
• Oral Cancer
• Digestive Organs--Diseases

Interventions

• DRUG
• RADIATION

Results Available

NCT03393962 | ENROLLING_BY_INVITATION | PHASE1/PHASE2

20 participants

Intervention of Ovarian Cancer With Antigen-specific Engineered Immune Effectors

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2025-12-01

Completion:

2028-01-31

Conditions

• Ovarian Cancer

Interventions

• BIOLOGICAL

No Results Yet