Clinical Trials

NCT05780684 | RECRUITING | NA

36 participants

Individualized Dose Escalation of 5-FU for Gastrointestinal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2023-07-14

Completion:

2027-09-30

Conditions

• Colorectal Cancer
• Esophagus Cancer
• Appendix Cancer
• Small Bowel Cancer
• Ampullary Cancer

Interventions

• OTHER

No Results Yet

NCT05773755 | RECRUITING | NA

20 participants

DBS for TRD With the Medtronic Percept PC

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2023-03-01

Completion:

2028-12-31

Conditions

• Major Depressive Disorder
• Treatment Resistant Depression

Interventions

• DEVICE

No Results Yet

NCT05773092 | ACTIVE_NOT_RECRUITING | PHASE2

30 participants

A Phase 2 Study of Osimertinib and S-1 in Treatment Resistant EGFR Mutant NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2023-08-01

Completion:

2025-10-24

Conditions

• NSCLC

Interventions

• DRUG

No Results Yet

NCT05767034 | COMPLETED | PHASE3

381 participants

Phase III Study of Efficacy and Safety of Secukinumab Versus Placebo, in Combination With Glucocorticoid Taper Regimen, in Patients With Polymyalgia Rheumatica (PMR)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2023-03-22

Completion:

2025-09-10

Conditions

• Polymyalgia Rheumatica

Interventions

• DRUG
• OTHER

No Results Yet

NCT05763849 | RECRUITING | NA

120 participants

Interoceptive Exposure for Adolescents With Low Weight Eating Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2023-03-14

Completion:

2028-01-31

Conditions

• Anorexia Nervosa

Interventions

• BEHAVIORAL

No Results Yet

NCT05761197 | RECRUITING

70 participants

Oropharyngeal Candidiasis (OPC) and S-ECC

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-22

Start Date:

2024-09-01

Completion:

2028-08-31

Conditions

• Candida Infection
• Oral Thrush
• Early Childhood Caries

No Results Yet

NCT05756777 | RECRUITING | PHASE1

18 participants

A Study of Gilteritinib in Combination With Ivosidenib or Enasidenib in People With Acute Myeloid Leukemia (AML)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2023-10-25

Completion:

2027-04-21

Conditions

• Acute Myeloid Leukemia (AML)

Interventions

• DRUG

No Results Yet

NCT05742750 | COMPLETED | PHASE1/PHASE2

49 participants

A Phase Ib/II Clinical Study of Camrelizumab and Apatinib Plus GP in the Treatment of Advanced Biliary Tract Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2023-04-27

Completion:

2025-12-01

Conditions

• Locally Advanced Biliary Tract Cancer
• Metastatic Biliary Tract Cancer

Interventions

• DRUG

No Results Yet

NCT05737667 | ACTIVE_NOT_RECRUITING | NA

1454 participants

Advancing mHealth-supported Adoption and Sustainment of an Evidence-based Mental Health Intervention in Sierra Leone

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2023-02-15

Completion:

2026-12-31

Conditions

• Mental Health

Interventions

• BEHAVIORAL

No Results Yet

NCT05712746 | ACTIVE_NOT_RECRUITING

1600 participants

Samtasu Post-marketing General Drug Use-results Survey in Patients With Volume Overload in Heart Failure.

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-22

Start Date:

2023-03-03

Completion:

2026-05-07

Conditions

• Heart Failure

Interventions

• DRUG

No Results Yet

NCT05700149 | RECRUITING

300 participants

Integrated Molecular and Clinical Profiling to Improve Disease Characterization and Outcome Prediction in Nodal Marginal Zone Lymphoma

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-22

Start Date:

2024-04-11

Completion:

2026-12-31

Conditions

• Nodal Marginal Zone Lymphoma

No Results Yet

NCT05699785 | ACTIVE_NOT_RECRUITING | NA

500 participants

Comparison of Inflammatory Markers and Incidence of Comorbidities in Patients on Antiretroviral Therapy With Second-generation Anti-integrase Drugs on Triple Versus Dual Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2023-02-16

Completion:

2028-02-16

Conditions

• Hiv

Interventions

• OTHER

No Results Yet

NCT05696626 | RECRUITING | PHASE3

600 participants

Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2023-10-31

Completion:

2027-04-30

Conditions

• Metastatic Breast Cancer

Interventions

• DRUG

No Results Yet

NCT05693545 | ACTIVE_NOT_RECRUITING | PHASE2

1004 participants

GOALIE: Intramuscular vs. Enteral Penicillin Prophylaxis to Prevent Progression of Latent RHD Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2023-09-01

Completion:

2027-03-31

Conditions

• Rheumatic Heart Disease

Interventions

• DRUG

No Results Yet

NCT05681923 | RECRUITING

7320 participants

Platform for the Prospective Mother-child Study of the Determinants of Neurodevelopmental Disorders

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-22

Start Date:

2023-04-19

Completion:

2034-03-31

Conditions

• Autism Spectrum Disorder
• Neurodevelopmental Disorders

Interventions

• OTHER

No Results Yet

NCT05671133 | RECRUITING | NA

4000 participants

Effectiveness and Implementation of a Clinician Decision Support System to Prevent Suicidal Behaviors

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2025-02-25

Completion:

2028-05-31

Conditions

• Suicide
• Suicide, Attempted

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05641519 | ACTIVE_NOT_RECRUITING | NA

483 participants

Skills-Based Educational Strategies for Reduction of Vascular Events in Orange County

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2022-11-18

Completion:

2027-06-30

Conditions

• Hypertension

Interventions

• BEHAVIORAL

No Results Yet

NCT05637099 | COMPLETED

181 participants

The Value of Repeated BIOMarker Measurements During an SBT to Predict EXtubation Failure in ICU Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-22

Start Date:

2022-08-01

Completion:

2025-05-07

Conditions

• Weaning Failure
• Mechanical Ventilation
• Spontaneous Breathing Trial
• Extubation Failure

No Results Yet

NCT05617833 | RECRUITING | PHASE1

60 participants

Safety of Erythropoietin and Melatonin for Very Preterm Infants With Intraventricular Hemorrhage

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2024-04-30

Completion:

2027-09-30

Conditions

• Intraventricular Hemorrhage of Prematurity

Interventions

• COMBINATION_PRODUCT
• OTHER

No Results Yet

NCT05606068 | RECRUITING | NA

200 participants

A Novel Limb Cryocompression System for Prevention of Chemotherapy Induced Peripheral Neuropathy - Expansion Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2022-11-11

Completion:

2026-11-30

Conditions

• Chemotherapy-induced Peripheral Neuropathy

Interventions

• DEVICE

No Results Yet

NCT05582837 | RECRUITING | PHASE4

40 participants

Treatment of Meniere's Disease With Migraine Medications

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2022-08-01

Completion:

2027-12-30

Conditions

• Ménière

Interventions

• DRUG

No Results Yet

NCT05573126 | RECRUITING | PHASE1/PHASE2

95 participants

Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2023-01-11

Completion:

2028-02-29

Conditions

• Hormone Receptor-positive Breast Cancer
• Hormone Receptor Positive HER-2 Negative Breast Cancer
• Metastatic Breast Cancer

Interventions

• DRUG

No Results Yet

NCT05549661 | RECRUITING | PHASE1

25 participants

Onvansertib for the Treatment of Recurrent or Refractory Chronic Myelomonocytic Leukemia and Myelodysplastic Syndrome/MPN Overlap Neoplasms

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2023-04-04

Completion:

2027-06-01

Conditions

• Recurrent Chronic Myelomonocytic Leukemia
• Refractory Chronic Myelomonocytic Leukemia
• Myelodysplastic/Myeloproliferative Neoplasm, Not Otherwise Specified
• Recurrent Atypical Chronic Myeloid Leukemia
• Recurrent Myelodysplastic/Myeloproliferative Neoplasm
• Refractory Myelodysplastic/Myeloproliferative Neoplasm

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05526417 | RECRUITING | NA

33 participants

Individualized Prehabilitation for Enhancing Recovery and Surgical Outcomes in Patients Undergoing Radiotherapy and Surgery for Soft Tissue Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2022-06-08

Completion:

2028-06-08

Conditions

• Soft Tissue Sarcoma
• Stage I Soft Tissue Sarcoma of the Trunk and Extremities
• Stage II Soft Tissue Sarcoma of the Trunk and Extremities
• Stage III Soft Tissue Sarcoma of the Trunk and Extremities

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT05525858 | RECRUITING

1000 participants

KPMNG Study of MOlecular Profiling Guided Therapy Based on Genomic Alterations in Advanced Solid Tumors II

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-22

Start Date:

2022-09-28

Completion:

2026-09-30

Conditions

• Solid Tumor
• Advanced Solid Tumor
• Metastatic Cancer

Interventions

• DRUG

No Results Yet

NCT05524935 | ACTIVE_NOT_RECRUITING | PHASE2

12 participants

Olaparib in Combination With Pembrolizumab for Advanced Uveal Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2022-10-11

Completion:

2026-07-31

Conditions

• Uveal Melanoma
• Ocular Melanoma

Interventions

• DRUG

No Results Yet

NCT05490927 | COMPLETED | NA

30 participants

Ethnic Microaggressions and Smoking Behaviors Among Latinx Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2022-10-13

Completion:

2026-04-28

Conditions

• Smoking
• Discrimination, Racial

Interventions

• BEHAVIORAL

No Results Yet

NCT05455697 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

33 participants

Tafasitamab, Retifanlimab, and Rituximab in Combination With Standard Therapy for the Treatment of Diffuse Large B-cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2023-01-26

Completion:

2026-10-15

Conditions

• Diffuse Large B-Cell Lymphoma
• Grade 3b Follicular Lymphoma
• High Grade B-Cell Lymphoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL
• OTHER

No Results Yet

NCT05450627 | COMPLETED

1015 participants

Registry of Pancreatic Exocrine Insufficiency: Enzyme Dose Requirements and Outcomes in Pancreatic Exocrine Insufficiency Across Aetiologies

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-22

Start Date:

2021-06-01

Completion:

2025-09-30

Conditions

• Exocrine Pancreatic Insufficiency

Interventions

• DRUG

No Results Yet

NCT05449548 | RECRUITING | NA

42 participants

Lenalidomide in the Treatment of Mucosal Behçet's Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2023-04-01

Completion:

2026-12-30

Conditions

• Oral Ulcer

Interventions

• DRUG

No Results Yet

NCT05437640 | COMPLETED | NA

12 participants

Optimizing Protein Patterns for Skeletal Muscle Preservation and Sleep in the Medical Management of Parkinson Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2022-10-01

Completion:

2024-11-25

Conditions

• Parkinson Disease

Interventions

• BEHAVIORAL

Results Available

NCT05434897 | COMPLETED | PHASE1/PHASE2

30 participants

A Study to Evaluate the Safety, Tolerability and Efficacy of AK3280 Cream on Hypertrophic Scar

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2022-07-08

Completion:

2023-07-18

Conditions

• Hypertrophic Scar

Interventions

• DRUG

No Results Yet

NCT05434234 | RECRUITING | PHASE1/PHASE2

312 participants

A Study of YL201 in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2022-05-25

Completion:

2027-04-06

Conditions

• Advanced Solid Tumor

Interventions

• DRUG

No Results Yet

NCT05398809 | RECRUITING | PHASE2

70 participants

Evaluate the Efficacy and Safety of Ruxolitinib on Hair Regrowth in Patients With Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)-Associated Alopecia Areata

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2023-01-18

Completion:

2027-12-01

Conditions

• Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (Apeced)
• Alopecia Areata

Interventions

• DRUG

No Results Yet

NCT05394428 | RECRUITING

300 participants

A Multi Center Study of Sexual Toxicities After Radiotherapy

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-22

Start Date:

2022-10-04

Completion:

2027-08-31

Conditions

• Malignant Neoplasms

Interventions

• OTHER

No Results Yet

NCT05374928 | COMPLETED

316 participants

Human Epilepsy Project 3

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-22

Start Date:

2020-03-09

Completion:

2025-12-31

Conditions

• Idiopathic Generalized Epilepsy

No Results Yet

NCT05350527 | TERMINATED | NA

89 participants

Impact of Video Information Support on Preoperative Anxiety in Breast Cancer Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2022-06-22

Completion:

2025-12-18

Conditions

• Breast Cancer

Interventions

• OTHER

No Results Yet

NCT05346536 | RECRUITING | NA

63 participants

Liquid Biopsy and Pancreas Cancer: Detection of AXL(+) CTCs (CTC-AXL-PANC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2022-06-16

Completion:

2025-09-19

Conditions

• Pancreatic Ductal Adenocarcinoma
• Metastatic Pancreatic Cancer
• Circulating Tumor Cell

Interventions

• OTHER

No Results Yet

NCT05345925 | COMPLETED | NA

5 participants

PV Loops With CNT in Multiple Pacing Sites

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-22

Start Date:

2023-05-19

Completion:

2023-11-11

Conditions

• Bradycardia
• A-V Block

Interventions

• DEVICE

No Results Yet

NCT05342493 | RECRUITING

1000 participants

Specified Drug Use Survey on AJOVY Subcutaneous Injection for Long-term Use

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-22

Start Date:

2022-04-20

Completion:

2026-09-30

Conditions

• Migraine Disorders

Interventions

• DRUG

No Results Yet