Clinical Trials

NCT05755620 | COMPLETED | PHASE1

50 participants

A Study to Evaluate the Safety and Immunogenicity of a Single Dose of H1ssF-3928 mRNA-LNP in Healthy Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2023-04-05

Completion:

2025-10-03

Conditions

• Influenza

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT05750459 | COMPLETED | PHASE4

90 participants

Pharmacokinetic Study of IV Artesunate to Treat Children With Severe Malaria

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2023-11-29

Completion:

2025-04-01

Conditions

• Plasmodium Falciparum Infection

Interventions

• DRUG

Results Available

NCT05738486 | ACTIVE_NOT_RECRUITING | PHASE3

1175 participants

A Study of Different Donanemab (LY3002813) Dosing Regimens in Adults With Early Alzheimer's Disease (TRAILBLAZER-ALZ 6)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2023-02-28

Completion:

2024-05-16

Conditions

• Alzheimer's Disease
• Dementia
• Brain Diseases
• Central Nervous System Diseases
• Nervous System Diseases
• Neurodegenerative Diseases
• Neurocognitive Disorders
• Mental Disorders

Interventions

• DRUG

Results Available

NCT05729932 | RECRUITING | PHASE1

15 participants

Cannabis and Opioid Use Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2024-09-10

Completion:

2027-06-30

Conditions

• Opioid Use Disorder

Interventions

• DRUG

No Results Yet

NCT05721443 | COMPLETED | PHASE2

28 participants

Cetuximab Plus Dalpicilib in Patients With HPV Negative, PD-1 Resistant R/M HNSCC

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2022-12-01

Completion:

2024-11-01

Conditions

• Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT05718180 | NOT_YET_RECRUITING | NA

105 participants

Intrapartum Ultrasound for Assessment of Fetal Progression

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2026-07-01

Completion:

2029-07-31

Conditions

• Labor, Obstetric

Interventions

• OTHER

No Results Yet

NCT05710328 | ACTIVE_NOT_RECRUITING | PHASE2

235 participants

Testing the Role of FDG-PET/CT to Predict Response to Therapy Prior to Surgery for HER2-positive Breast Cancer, The DIRECT Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2023-05-10

Completion:

2027-05-31

Conditions

• Anatomic Stage II Breast Cancer AJCC v8
• Anatomic Stage III Breast Cancer AJCC v8
• HER2-Positive Breast Carcinoma
• Invasive Breast Carcinoma

Interventions

• DRUG
• PROCEDURE
• OTHER

No Results Yet

NCT05708950 | COMPLETED | PHASE1/PHASE2

40 participants

A Clinical Trial of KVA12123 [TBS-2025] Treatment Alone and in Combination With Pembrolizumab In Advanced Solid Tumors (VISTA-101)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2023-03-03

Completion:

2025-10-16

Conditions

• Cancer
• Solid Tumor
• Melanoma
• Carcinoma
• Sarcoma
• Lung Cancer
• Prostate Cancer
• Breast Cancer
• Colo-rectal Cancer
• Uterine Cancer
• Pancreatic Cancer
• Gastric Cancer
• Esophageal Cancer
• Thyroid Cancer
• Ovarian Cancer
• Kidney Cancer
• Head and Neck Cancer

Interventions

• DRUG

No Results Yet

NCT05694715 | RECRUITING | PHASE1

24 participants

Combination Therapy in Cancers With Mutations in DNA Repair Genes

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2023-05-23

Completion:

2028-01-31

Conditions

• Metastatic Solid Tumor
• BRCA1 Mutation
• BRCA2 Mutation
• ATM Gene Mutation
• PALB2 Gene Mutation

Interventions

• DRUG

No Results Yet

NCT05689944 | RECRUITING | NA

160 participants

Dance-therapy and Chronic Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2024-03-01

Completion:

2030-10-31

Conditions

• Chronic Pain
• Complex Regional Pain Syndromes
• Tension-Type Headache

Interventions

• BEHAVIORAL

No Results Yet

NCT05661578 | COMPLETED | PHASE2

64 participants

A Study to Evaluate the Safety and Pharmacokinetics of the Intravenous Fixed-Dose Combination (IV FDC) of Tiragolumab and Atezolizumab in Participants With Locally Advanced, Recurrent or Metastatic Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2023-05-04

Completion:

2025-12-26

Conditions

• PD-L1-selected Solid Tumors

Interventions

• DRUG

Results Available

NCT05654194 | COMPLETED | PHASE3

60 participants

Azacitidine Combined With Venetoclax and ATRA in Newly Diagnosed AML

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2022-10-31

Completion:

2024-09-29

Conditions

• Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT05648110 | COMPLETED | PHASE2/PHASE3

3882 participants

Parent Study: Study Understanding Pre-Exposure pRophylaxis of NOvel Anitbodies (SUPERNOVA) Sub-study: Study Understanding Pre-Exposure pRophylaxis of NOvel Anitbodies (SUPERNOVA Sub-study)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2022-12-16

Completion:

2024-03-29

Conditions

• COVID-19, SARS-CoV-2

Interventions

• BIOLOGICAL

Results Available

NCT05644080 | COMPLETED | NA

10 participants

68Ga/177Lu-PSMA Theranostics in Recurrent Grade 3 and Grade 4 Glioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2023-03-28

Completion:

2025-04-11

Conditions

• High Grade Glioma

Interventions

• RADIATION

No Results Yet

NCT05637814 | RECRUITING | NA

320 participants

Dynamic Critical Congenital Heart Screening With Addition of Perfusion Measurements

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2023-08-17

Completion:

2027-06-30

Conditions

• Congenital Heart Disease

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05637216 | ACTIVE_NOT_RECRUITING | PHASE2

43 participants

Losartan to Reduce Radiation Induced Fibrosis in Breast Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2023-08-17

Completion:

2027-08-17

Conditions

• Radiation Induced Fibrosis

Interventions

• DRUG

No Results Yet

NCT05622396 | COMPLETED | NA

20 participants

Feasibility of an Adapted Mindfulness Program to Parkinson's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2023-02-06

Completion:

2023-12-06

Conditions

• Parkinson Disease

Interventions

• PROCEDURE

No Results Yet

NCT05609253 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

10 participants

Itraconazole to Prevent Recurrent Barrett's Esophagus

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2022-09-14

Completion:

2024-02-23

Conditions

• Barrett Oesophagitis With Dysplasia

Interventions

• DRUG

No Results Yet

NCT05597358 | COMPLETED | NA

145 participants

Efficacy of High Intensity Laser for Provoked Vestibulodynia

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2022-10-26

Completion:

2025-11-16

Conditions

• Vulvodynia

Interventions

• RADIATION

No Results Yet

NCT05548556 | ACTIVE_NOT_RECRUITING | PHASE2

51 participants

A Study to Evaluate RO7204239 in Participants With Facioscapulohumeral Muscular Dystrophy

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2023-02-07

Completion:

2025-05-02

Conditions

• Facioscapulohumeral Muscular Dystrophy (FSHD)

Interventions

• DRUG

No Results Yet

NCT05538091 | RECRUITING | PHASE2

48 participants

Vismodegib Combined With Atezolizumab in Platinum Resistant Ovarian, Fallopian Tube, and Primary Peritoneal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2023-05-15

Completion:

2031-08-30

Conditions

• Platinum-Resistant Fallopian Tube Carcinoma
• Platinum-Resistant Primary Peritoneal Carcinoma
• PARP Inhibitor
• Hedgehog Inhibitor

Interventions

• DRUG

No Results Yet

NCT05537402 | TERMINATED | PHASE2

1 participants

LOcoregional vs Systemic Therapy in Patients With BCLC Stage B HCC

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2023-09-27

Completion:

2025-06-06

Conditions

• Hepatocellular Carcinoma

Interventions

• DRUG
• RADIATION

Results Available

NCT05514717 | TERMINATED | PHASE1

57 participants

A Study of XMT-2056 in Advanced/Recurrent Solid Tumors That Express HER2

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2023-01-24

Completion:

2026-05-22

Conditions

• HER2-positive Breast Cancer
• HER2-positive Gastric Cancer
• HER2-positive Non-Small Cell Lung Cancer
• HER2-positive Colorectal Cancer
• HER2-positive Tumors
• HER2 Low Breast Cancer

Interventions

• DRUG

No Results Yet

NCT05503953 | COMPLETED | PHASE3

318 participants

Phase III Study to Evaluate the Efficacy and Safety of AGSAVI in Patients With Essential Hypertension Inadequately Controlled With AGLS

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2022-10-18

Completion:

2025-06-10

Conditions

• Essential Hypertension

Interventions

• DRUG

No Results Yet

NCT05493163 | COMPLETED | PHASE4

558 participants

Catheter-directed Thrombolysis in Intermediate-high Risk Acute Pulmonary Embolism

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2022-10-19

Completion:

2026-03-30

Conditions

• Pulmonary Embolism

Interventions

• DRUG

No Results Yet

NCT05462561 | SUSPENDED | NA

5 participants

Vascularized Composite Bladder Allograft Transplantation

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2023-05-01

Completion:

2027-10-03

Conditions

• Neurogenic Bladder
• Bladder Dysfunction
• Immunosuppression

Interventions

• OTHER
• PROCEDURE

No Results Yet

NCT05452031 | RECRUITING | NA

672 participants

A Dyadic Sleep Health Approach for Persons With Alzheimer's Disease and Caregivers

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2022-11-09

Completion:

2027-05-31

Conditions

• Sleep

Interventions

• BEHAVIORAL

No Results Yet

NCT05410275 | RECRUITING | PHASE3

10 participants

Chronic Anticoagulation With a Reduced Dose Regimen of Rivaroxaban in End-stage Renal Disease Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2025-01-08

Completion:

2027-01-30

Conditions

• Chronic Hemodialysis Patients

Interventions

• DRUG

No Results Yet

NCT05406622 | ACTIVE_NOT_RECRUITING | NA

292 participants

MOTIV BTK Randomized Controlled Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2022-06-10

Completion:

2026-04-30

Conditions

• Critical Limb Ischemia

Interventions

• DEVICE

No Results Yet

NCT05403034 | COMPLETED | NA

8 participants

Study of the Biological Function of Muscle Satellite Cells From Patients With Obstetric Brachial Plexus Palsy

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2022-10-17

Completion:

2025-06-25

Conditions

• Obstetrical Brachial Plexus Palsy

Interventions

• PROCEDURE

No Results Yet

NCT05398263 | TERMINATED | PHASE3

125 participants

Tezepelumab Efficacy and Safety in Reducing Oral Corticosteroid Use in Adults With Oral Corticosteroid Dependent Asthma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2022-08-09

Completion:

2025-03-24

Conditions

• Asthma

Interventions

• BIOLOGICAL
• OTHER

Results Available

NCT05389449 | ACTIVE_NOT_RECRUITING | PHASE3

80 participants

A Long-term Safety and Efficacy Study of Danicopan as an Add-on Therapy to Complement Component 5 Inhibitor (C5i) in Participants With PNH

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2022-10-28

Completion:

2026-08-24

Conditions

• Paroxysmal Nocturnal Hemoglobinuria

Interventions

• DRUG

No Results Yet

NCT05385432 | RECRUITING | PHASE3

244 participants

Induction in Sensitized Kidney Transplant Recipients Without Pre-existing Donor-specific antiboDies

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2023-11-07

Completion:

2030-12-30

Conditions

• Renal Transplant Rejection
• Induction Therapy

Interventions

• DRUG

No Results Yet

NCT05380544 | ACTIVE_NOT_RECRUITING | NA

77 participants

Extracorporeal Shockwave Therapy for Diabetic Foot Ulcers

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2022-04-13

Completion:

2023-10-31

Conditions

• Diabetic Foot

Interventions

• DEVICE

No Results Yet

NCT05378464 | SUSPENDED | PHASE1

28 participants

Adoptive T Cell Therapy Following HER2-Pulsed Dendritic Cell Vaccine & Pepinemab /Trastuzumab in Patients w/ Metastatic HER2+ Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2022-05-31

Completion:

2026-08-31

Conditions

• HER2-positive Breast Cancer

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT05345457 | TERMINATED | PHASE4

1 participants

Outpatient Antibiotics Following Previable Rupture of Membranes (pPPROM) Between 18 0/7 and 22 6/7 Weeks Gestational Age

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2023-01-13

Completion:

2024-02-26

Conditions

• Pregnancy Preterm
• Pregnancy Prom
• PROM, Preterm (Pregnancy)
• PROM (Pregnancy)
• Premat Rupture Membranes Preterm Unspec to Length of Time Between Rupture/Labor
• Premature Birth

Interventions

• DRUG

Results Available

NCT05334719 | COMPLETED

500 participants

A Study of the Effectiveness and Safety of Nivolumab Plus Chemotherapy in Participants With Untreated Advanced/Recurrent Gastric Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-18

Start Date:

2022-06-29

Completion:

2026-01-16

Conditions

• Stomach Neoplasms

No Results Yet

NCT05325242 | ACTIVE_NOT_RECRUITING | NA

13 participants

Elbow Artery Embolization for Tennis Elbow

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2023-03-21

Completion:

2027-12-31

Conditions

• Lateral Epicondylitis, Unspecified Elbow

Interventions

• DEVICE

No Results Yet

NCT05299554 | COMPLETED | PHASE3

76 participants

Long-term Safety Study of Chronocort in the Treatment of Participants With Congenital Adrenal Hyperplasia

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2022-04-01

Completion:

2026-01-15

Conditions

• Congenital Adrenal Hyperplasia

Interventions

• DRUG

No Results Yet

NCT05287542 | COMPLETED | NA

90 participants

Hypnosis in Working Memory Rehabilitation

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2022-12-15

Completion:

2025-06-20

Conditions

• Cognitive Rehabilitation
• Brain Injuries
• Cognitive Impairment
• Working Memory

Interventions

• OTHER

No Results Yet