Clinical Trials

NCT06307548 | RECRUITING | PHASE1/PHASE2

21 participants

Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2024-07-30
Completion:: 2027-06-01

Conditions

Locally Advanced Colorectal Carcinoma
Recurrent Colorectal Carcinoma
Stage III Colorectal Cancer

Interventions

DRUG
PROCEDURE

No Results Yet

NCT06297265 | RECRUITING | NA

50 participants

Manual Lymphatic Drainage Breast Massage in Breast Cancer Patients After Breast Conserving Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2024-05-24
Completion:: 2026-12-31

Conditions

Anatomic Stage 0 Breast Cancer AJCC v8
Anatomic Stage IA Breast Cancer AJCC v8
Localized Breast Carcinoma

Interventions

OTHER
RADIATION

No Results Yet

NCT06293365 | ACTIVE_NOT_RECRUITING | PHASE2

155 participants

Two-period Crossover Study to Demonstrate the Comparability of Pharmacokinetics of Subcutaneous Ianalumab Between 2mL Auto-injector/2mL PFS with1mL Pre-filled Syringe in Adult Participants With Autoimmune Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2024-07-02
Completion:: 2026-02-17

Conditions

Sjögrens Disease
Systemic Lupus Erythematosus
Rheumatoid Arthritis

Interventions

BIOLOGICAL

No Results Yet

NCT06291857 | COMPLETED | PHASE3

9320 participants

A Study to Evaluate the Safety and Immunogenicity of COVID-19 Vaccine and Influenza Combination Vaccine

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2024-12-09
Completion:: 2025-12-24

Conditions

COVID-19

Interventions

BIOLOGICAL

No Results Yet

NCT06287034 | RECRUITING

102 participants

The Role of the Free/Pedunculated Flap in Total Laryngectomy After (Chemo-)Radiotherapy Failure for Laryngeal Carcinoma: Impact on the Risk of Pharyngocutaneous Fistula (PCF)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-05
Start Date:: 2023-03-21
Completion:: 2025-03-21

Conditions

Larynx Carcinoma

Interventions

PROCEDURE

No Results Yet

NCT06284122 | RECRUITING | PHASE3

790 participants

Study of Mosunetuzumab Plus Lenalidomide Compared to Anti-CD20 Anti-body + Chemotherapy in Follicular Lymphoma FLIPI2-5

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2024-06-07
Completion:: 2028-11-30

Conditions

Follicular Lymphoma

Interventions

DRUG

No Results Yet

NCT06269107 | COMPLETED | PHASE3

485 participants

A Research Study to See How Well New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Levels in People With Type 2 Diabetes (T2D), Compared to Daily Insulin Glargine (COMBINE 4)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2024-02-15
Completion:: 2025-05-27

Conditions

Type 2 Diabetes

Interventions

DRUG

No Results Yet

NCT06253858 | RECRUITING | NA

10 participants

Ultrasound (US) Guided External Ventricular Catheter Placement

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2026-04-01
Completion:: 2026-12-01

Conditions

Hydrocephalus

Interventions

DEVICE

No Results Yet

NCT06250322 | COMPLETED

307 participants

A Multicenter, Observational, Single Arm Study of the TECNIS Presbyopia-correcting Intraocular Lens

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-05
Start Date:: 2024-04-10
Completion:: 2025-06-30

Conditions

Cataracts

Interventions

DEVICE

No Results Yet

NCT06242691 | COMPLETED | PHASE1/PHASE2

13 participants

Safety and Efficacy of MK-1200 in Participants With Advanced Solid Tumors (MK-1200-002)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2024-02-28
Completion:: 2025-06-17

Conditions

Advanced Solid Tumors

Interventions

BIOLOGICAL
DRUG

Results Available

NCT06240195 | RECRUITING

60 participants

Biomarkers of Efficacy and Tolerability of Sacituzumab-Govitecan in the Treatment of Patients With Triple-negative Breast Cancer in the Metastatic Phase: Prospective Multicenter Real-world Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-05
Start Date:: 2023-01-17
Completion:: 2025-01-17

Conditions

Breast Cancer

Interventions

OTHER

No Results Yet

NCT06235125 | RECRUITING | PHASE1

10 participants

Safety and Feasibility of Intraoperative Visualization With Cytalux in Children

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2024-04-08
Completion:: 2026-08-31

Conditions

Osteosarcoma
Pulmonary Metastasis
Fluorescence
Metastatic Sarcoma
Pediatrics

Interventions

DRUG

No Results Yet

NCT06214793 | SUSPENDED | PHASE2

61 participants

Taletrectinib in Previously Treated Metastatic CDH1-mutated Invasive Lobular Cancer (ILC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2026-10-31
Completion:: 2030-01-01

Conditions

Breast Cancer
Metastatic Breast Cancer

Interventions

DRUG

No Results Yet

NCT06191822 | COMPLETED | NA

1714 participants

Aspire2B Personalization Pilot Study Program

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2022-03-01
Completion:: 2023-09-01

Conditions

App Proficiency
Behavior
Lifestyle

Interventions

OTHER

No Results Yet

NCT06191575 | SUSPENDED

10 participants

7 Tesla MRI Neuroimaging in Testicular Cancer Patients With Hypogonadism and on Androgen Replacement Therapy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-05
Start Date:: 2022-11-29
Completion:: 2026-12-31

Conditions

Hypogonadism
Malignant Testicular Germ Cell Tumor

Interventions

PROCEDURE

No Results Yet

NCT06188442 | ACTIVE_NOT_RECRUITING | PHASE4

300 participants

Superiority of On-demand PrEP Versus PEP on Using Doxycycline for Preventing STI in MSM

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2025-03-29
Completion:: 2027-12-31

Conditions

Sexually Transmitted Diseases, Bacterial
Syphilis
Gonorrhea
Chlamydia

Interventions

DRUG

No Results Yet

NCT06171685 | ACTIVE_NOT_RECRUITING | PHASE2

300 participants

MMRC Horizon One: RRMM (MMRC-099)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2024-11-17
Completion:: 2029-07-31

Conditions

Relapse Multiple Myeloma
Refractory Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT06159985 | COMPLETED | NA

270 participants

Effect of Left Posterior Pericardiotomy for the Prevention of POAF

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2023-12-11
Completion:: 2025-12-09

Conditions

Coronary Artery Disease
Atrial Fibrillation New Onset
Pericardial Effusion

Interventions

PROCEDURE

No Results Yet

NCT06138808 | ENROLLING_BY_INVITATION

400 participants

5-SENSE Score Validation Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-05
Start Date:: 2024-01-09
Completion:: 2027-01-31

Conditions

Epilepsy Intractable

Interventions

OTHER

No Results Yet

NCT06133413 | ACTIVE_NOT_RECRUITING | NA

182 participants

Connected Scales to Optimize the Maintenance of Weight Lost After Bariatric Surgery and Limit Failures and Reoperations

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2025-06-26
Completion:: 2027-02-28

Conditions

Obesity, Severe
Surgery

Interventions

DEVICE
OTHER

No Results Yet

NCT06132737 | RECRUITING | PHASE1/PHASE2

15 participants

[90Y]Y-PTT Endoradiotherapy in CNS Lymphoma Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2023-11-07
Completion:: 2027-09-23

Conditions

CNS Lymphoma

Interventions

DRUG

No Results Yet

NCT06126120 | COMPLETED

231 participants

Colonoscopy Check-up in People With Lynch Syndrome

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-05
Start Date:: 2024-01-17
Completion:: 2024-04-04

Conditions

Lynch Syndrome

Results Available

NCT06122675 | RECRUITING | NA

10 participants

Cerebellar Deep Brain Stimulation for Movement Disorders in Cerebral Palsy in Children and Young Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2024-03-26
Completion:: 2029-01-01

Conditions

Dyskinetic Cerebral Palsy
Dystonic Cerebral Palsy

Interventions

DEVICE

No Results Yet

NCT06117020 | COMPLETED | PHASE1

89 participants

Single and Multiple Ascending Dose Study of MTR-601 in Healthy Individuals

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2023-09-11
Completion:: 2024-10-16

Conditions

Muscle Spasticity
Hypertonia, Muscle
Cerebral Palsy
Multiple Sclerosis
Stroke
Hereditary Spastic Paraplegia
Dystonia
Spinal Cord Injuries

Interventions

DRUG

Results Available

NCT06067984 | COMPLETED | PHASE3

73 participants

An Extension Study of a Second Course of a Digital Therapeutic for the Treatment of Experiential Negative Symptoms of Schizophrenia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2023-09-12
Completion:: 2025-06-13

Conditions

Schizophrenia
Negative Symptoms in Schizophrenia

Interventions

DEVICE

No Results Yet

NCT06049797 | COMPLETED

999 participants

A Study Following Women in Menopause Treated With a Non-hormonal Therapy for Hot Flashes and Night Sweats

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-05
Start Date:: 2023-11-15
Completion:: 2025-09-06

Conditions

Hot Flashes

Interventions

DRUG

No Results Yet

NCT06003751 | COMPLETED | PHASE2

27 participants

A Study of PER-001 in Participants With Diabetic Retinopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2023-08-05
Completion:: 2025-04-03

Conditions

Diabetic Retinopathy

Interventions

DRUG

No Results Yet

NCT05995418 | RECRUITING

9510 participants

Study on the Health Economic Burden of Alzheimer's Disease in China

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-05
Start Date:: 2023-07-01
Completion:: 2026-06-30

Conditions

Alzheimer Disease

Interventions

OTHER

No Results Yet

NCT05986994 | COMPLETED

45 participants

Identification of a Pool of miRNA to Improve Early Management of Perinatal Asphyxia and Hypoxic Ischemic Encephalopathy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-05
Start Date:: 2023-07-18
Completion:: 2024-07-18

Conditions

Hypoxic-Ischemic Encephalopathy
Asphyxia Perinatal

Interventions

OTHER
DIAGNOSTIC_TEST

No Results Yet

NCT05967299 | RECRUITING | PHASE1

96 participants

Study of Intravenous ZMA001 in Healthy Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2023-11-27
Completion:: 2027-09-01

Conditions

Pulmonary Arterial Hypertension PAH

Interventions

OTHER
DRUG

No Results Yet

NCT05946031 | COMPLETED | EARLY_PHASE1

87 participants

Testing the ETM: Examination and Comparison of Different Methods

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2024-12-02
Completion:: 2025-08-14

Conditions

Cigarette Smoking

Interventions

DRUG

No Results Yet

NCT05941325 | SUSPENDED | PHASE2

20 participants

A Single-arm, Open-label, Single-center Prospective Study of Fruquintinib Combined With Envafolimab in the Treatment of Advanced or Unresectable Locally Advanced Bone and Soft Tissue Sarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2023-04-01
Completion:: 2026-12-01

Conditions

Advanced or Unresectable Locally Advanced Bone and Soft Tissue Sarcoma

Interventions

DRUG

No Results Yet

NCT05937776 | COMPLETED

4 participants

Developing a New Metabolic Imaging Approach (aMRI) for Evaluating Neurological Disease in Patients With Gliomas

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-05
Start Date:: 2023-12-11
Completion:: 2025-12-31

Conditions

Glioma

Interventions

OTHER
PROCEDURE

No Results Yet

NCT05924802 | ACTIVE_NOT_RECRUITING | NA

50 participants

Physiological Effects Ketone Ester in Heart

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2024-06-01
Completion:: 2026-05-29

Conditions

Heart Failure

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05916196 | RECRUITING | PHASE2

30 participants

[18F]FES PET/.CT in Uterine Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2024-04-05
Completion:: 2027-08-01

Conditions

Uterine Cancer

Interventions

DRUG

No Results Yet

NCT05853939 | COMPLETED | NA

106 participants

Measuring rTMS-induced Neuroplasticity With EEG Steady-state Visual-evoked Potentials

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2023-07-01
Completion:: 2026-06-02

Conditions

Visual Cortical Plasticity
Repetitive Transcranial Magnetic Stimulation
Visual Attention

Interventions

DEVICE

No Results Yet

NCT05849467 | RECRUITING | PHASE1

15 participants

Central Nervous System Uptake of Anti-CD8+ T Cell Minibodies in Multiple Sclerosis and Progressive Multifocal Leukoencephalopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2023-10-19
Completion:: 2030-04-01

Conditions

Progressive Multifocal Leukoencephalopathy
Multiple Sclerosis
Other Neuroinflammatory Diseases With BBB Leakage

Interventions

DRUG

No Results Yet

NCT05846685 | COMPLETED

10 participants

Patient Perspectives of an Automated Falls-Risk Screening and Referral Tool in the Emergency Department (ED)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-05
Start Date:: 2022-02-22
Completion:: 2026-02-28

Conditions

Falls-Risk

Interventions

OTHER

No Results Yet

NCT05828953 | ACTIVE_NOT_RECRUITING | PHASE2

30 participants

Anlotinib Capsules in the Treatment for IPF/PF-ILDs

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-05
Start Date:: 2021-09-28
Completion:: 2026-09-30

Conditions

Interstitial Lung Diseases

Interventions

DRUG

No Results Yet

NCT05824689 | TERMINATED

124 participants

Fluoroquinolone Resistance Prevalence Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-05
Start Date:: 2022-07-08
Completion:: 2024-12-17

Conditions

Multiple Myeloma

Results Available