Clinical Trials

NCT06875128 | RECRUITING | PHASE2

90 participants

Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Breast Cancer w/Liver Dominant Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2026-01-29

Completion:

2029-05-31

Conditions

• Metastatic Breast Cancer in the Liver

Interventions

• DRUG

No Results Yet

NCT06873581 | RECRUITING | PHASE3

266 participants

Pivotal Study of Voro Urologic Scaffold

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-04-18

Completion:

2028-04-30

Conditions

• Radical Prostatectomy
• Stress Urinary Incontinence (SUI)

Interventions

• DEVICE

No Results Yet

NCT06868914 | NOT_YET_RECRUITING | PHASE1

35 participants

Phase I Trial of High-Density Theta Burst Stimulation (hdTBS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2026-06-04

Completion:

2028-01-13

Conditions

• Healthy Volunteers

Interventions

• DEVICE

No Results Yet

NCT06864988 | ACTIVE_NOT_RECRUITING | PHASE3

480 participants

4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-03-03

Completion:

2027-06-30

Conditions

• Macular Neovascularization Secondary to Age-Related Macular Degeneration

Interventions

• BIOLOGICAL

No Results Yet

NCT06860607 | RECRUITING | PHASE1

44 participants

Environment and Alcohol: A Pilot Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2026-06-04

Completion:

2027-03-01

Conditions

• Alcohol Use Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT06858319 | RECRUITING | PHASE3

220 participants

Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy.

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-07-28

Completion:

2031-06-25

Conditions

• Kidney Diseases
• Kidney Diseases, Chronic
• Urological Diseases
• Glomerulonephritis
• Glomerular Disease
• Glomerulonephritis, IGA
• Glomerulopathy
• Immunoglobulin Disease

Interventions

• DRUG

No Results Yet

NCT06857955 | ACTIVE_NOT_RECRUITING | PHASE2

385 participants

A Study to Identify an Optimal Dose of QCZ484 in Mild to Moderate Hypertensive Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-03-26

Completion:

2027-01-29

Conditions

• Hypertension

Interventions

• OTHER
• DRUG

No Results Yet

NCT06857084 | RECRUITING

400 participants

Evaluation Of Outcomes Following Rotator Cuff Repair Using the REGENETEN Bioinductive Implant

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-01

Start Date:

2020-10-01

Completion:

2029-12-31

Conditions

• Rotator Cuff Injuries

Interventions

• DEVICE

No Results Yet

NCT06855498 | RECRUITING | PHASE3

600 participants

Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-02-28

Completion:

2028-02-28

Conditions

• Hidradenitis Suppurativa (HS)

Interventions

• DRUG

No Results Yet

NCT06852365 | RECRUITING | PHASE2

100 participants

Combined Oral Contraceptive Pill and Resistance Starch

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-06-10

Completion:

2028-04-30

Conditions

• Metabolic Syndrome
• Polycystic Ovary Syndrome

Interventions

• DIETARY_SUPPLEMENT
• DRUG

No Results Yet

NCT06851767 | ENROLLING_BY_INVITATION | PHASE1/PHASE2

18 participants

Base-Edited Hematopoietic Stem/Progenitor Cell X-Linked Severe Combined Immunodeficiency Gene Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-05-09

Completion:

2034-12-31

Conditions

• X-linked Severe Combined Immunodeficiency
• X-SCID
• XSCID

Interventions

• GENETIC
• DRUG
• BIOLOGICAL

No Results Yet

NCT06846281 | RECRUITING | PHASE3

360 participants

Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-07-23

Completion:

2029-07-24

Conditions

• Relapsing Multiple Sclerosis

Interventions

• DRUG

No Results Yet

NCT06845761 | ACTIVE_NOT_RECRUITING | NA

100 participants

Examining the Relationship Between Ongoing Alcohol Use, Suicidal Thoughts and Behaviors and Related Constructs, and Behavioral Economic Decision-Making

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-05-09

Completion:

2026-08-31

Conditions

• Alcohol Use
• Suicidal Ideation/Behavior

Interventions

• BEHAVIORAL

No Results Yet

NCT06844240 | ENROLLING_BY_INVITATION

96 participants

Efficacy and Safety of XEN63 Gel Implant

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-01

Start Date:

2024-11-28

Completion:

2030-12-31

Conditions

• Glaucoma

No Results Yet

NCT06844214 | RECRUITING | PHASE1/PHASE2

32 participants

A Study to Investigate the Safety, Tolerability, and Efficacy of SAR446268, an Adeno-associated Viral Vector-mediated Gene Therapy in Participants Aged 10 to 55 Years of Age With Non-congenital Myotonic Dystrophy Type 1

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-07-23

Completion:

2029-02-28

Conditions

• Myotonic Dystrophy

Interventions

• BIOLOGICAL

No Results Yet

NCT06833008 | RECRUITING | PHASE1/PHASE2

85 participants

A Study to Assess a New Medicine Called IPN01195 When Administered Alone in Adults With Advanced Solid Tumours

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-03-14

Completion:

2028-10-03

Conditions

• Advanced Solid Tumor

Interventions

• DRUG

No Results Yet

NCT06830720 | RECRUITING

3250 participants

A Non-interventional Study for Kisqali (Ribociclib) in Combination With an Aromatase Inhibitor for Adjuvant Treatment in Patients With HR+/HER2- Early Breast Cancer at High Risk of Recurrence

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-01

Start Date:

2025-02-20

Completion:

2030-06-30

Conditions

• Breast Neoplasms

Interventions

• DRUG

No Results Yet

NCT06827132 | ACTIVE_NOT_RECRUITING

600 participants

Observational Study Evaluate Pathology Practice Use Artificial Intelligence in Patient Suspected Lung and Breast Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-01

Start Date:

2025-10-25

Completion:

2027-05-31

Conditions

• Lung Cancer
• Breast Cancer

No Results Yet

NCT06822738 | RECRUITING | PHASE3

130 participants

A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-02-11

Completion:

2028-11-30

Conditions

• Primary Open Angle Glaucoma

Interventions

• DEVICE

No Results Yet

NCT06821230 | RECRUITING | NA

200 participants

Dyadic Mindfulness for People With Parkinson's Disease and Their Caregivers

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-02-11

Completion:

2027-06-30

Conditions

• Mindfulness
• Caregivers
• Movement Disorders
• Neurodegenerative Disease
• Dyadic Intervention
• Psychosocial Health
• Parkinsons Disease

Interventions

• BEHAVIORAL

No Results Yet

NCT06821139 | COMPLETED

28700 participants

Cohort Study of Intraoperative Lung Protective Ventilation Trends in a Large Canadian Health Authority

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-01

Start Date:

2014-01-01

Completion:

2023-12-31

Conditions

• Lung Protective Ventilation
• Intraoperative Ventilation
• COVID
• COVID - 19
• Non-cardiac Surgery

No Results Yet

NCT06820463 | RECRUITING | PHASE2

390 participants

A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-04-24

Completion:

2028-03-31

Conditions

• Metastatic Colorectal Cancer

Interventions

• DRUG

No Results Yet

NCT06819189 | RECRUITING | PHASE1

50 participants

Role of Metal Ion Transporter ZIP8 in Alcohol-Related Behaviors

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-06-10

Completion:

2027-12-31

Conditions

• Healthy Volunteer

Interventions

• DRUG

No Results Yet

NCT06818747 | RECRUITING | NA

334 participants

Effectiveness of PKP vs DSAEK in Terms of 2-year Postoperative Visual Acuity in Advanced BPK

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-05-21

Completion:

2027-05-21

Conditions

• Bullous Pseudophakic Keratopathy
• Penetrating Keratoplasty

Interventions

• PROCEDURE

No Results Yet

NCT06811129 | COMPLETED

328 participants

Long-Term Neurologic and Neurocognitive Sequelae Following Pediatric Ebola Virus in Liberia

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-01

Start Date:

2025-02-14

Completion:

2025-09-09

Conditions

• Ebola
• Post-Acute Ebola Syndrome

No Results Yet

NCT06810310 | RECRUITING | PHASE2

24 participants

Psilocybin on Brain Mechanisms of Motivation in OUD

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-12-22

Completion:

2027-05-01

Conditions

• Opioid Use Disorder

Interventions

• DRUG

No Results Yet

NCT06808685 | RECRUITING

133 participants

Real World Multicenter National Study to Evaluate the Effectiveness and Safety of Biosimilar Bevacizumab Elovie

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-01

Start Date:

2025-06-01

Completion:

2027-11-30

Conditions

• Metastatic Colorectal Cancer

No Results Yet

NCT06805656 | NOT_YET_RECRUITING | PHASE2

70 participants

Multi Interventional Approaches to Mitigate HIV Reservoirs Aiming the Sustained HIV Remission Without Antiretrovirals

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2026-07-01

Completion:

2027-01-01

Conditions

• Hiv
• HIV I Infection

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT06805630 | RECRUITING | NA

50 participants

Urine Methylation Markers in UTUC

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-05-07

Completion:

2026-06-30

Conditions

• Upper Tract Urothelial Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06802445 | COMPLETED | NA

48 participants

The Effect of Non-Invasive Vagal Nerve Stimulation Combined With Self-Managed Therapy in Individuals With Myogenic Temporomandibular Dysfunction

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2024-10-01

Completion:

2026-02-02

Conditions

• Temporomandibular Disorders (TMD)

Interventions

• OTHER
• DEVICE

No Results Yet

NCT06799650 | ACTIVE_NOT_RECRUITING | PHASE2

40 participants

Clinical Trial of Gammora® Plus Antiretroviral Treatment for HIV

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-01-01

Completion:

2025-11-01

Conditions

• HIV Seropositivity

Interventions

• DRUG

No Results Yet

NCT06799429 | RECRUITING | NA

50 participants

Train Your Brain Fitness SC: An Exercise Intervention for People With Cognitive Impairments

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2026-03-13

Completion:

2026-10-31

Conditions

• Mild-moderate Cognitive Impairment

Interventions

• BEHAVIORAL

No Results Yet

NCT06798896 | RECRUITING | PHASE2

216 participants

RENAISSANCE 2: SPN-817 Phase 2, Double-Blind, Placebo-Controlled Study in Adults With Focal Onset Seizures

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2024-12-30

Completion:

2027-08-31

Conditions

• Focal Onset Seizures

Interventions

• DRUG

No Results Yet

NCT06788912 | RECRUITING | PHASE2

60 participants

Pembrolizumab (MK-3475) Plus Investigational Agents in Resectable Non-small Cell Lung Cancer (NSCLC) (MK-3475-01E/KEYMAKER-U01)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-03-20

Completion:

2032-02-06

Conditions

• Lung Neoplasm Malignant

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06772623 | RECRUITING | PHASE1/PHASE2

252 participants

Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-03-06

Completion:

2027-11-30

Conditions

• Non Small Cell Lung Carcinoma

Interventions

• DRUG

No Results Yet

NCT06772025 | RECRUITING | NA

200 participants

A Study to Understand How Cardiac Surgery-associated Acute Kidney Injury Develops in Participants Who Undergo Heart Surgery With the Use of Heart-lung Machine

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-02-03

Completion:

2027-01-31

Conditions

• Cardiac Surgery-associated Acute Kidney Injury

Interventions

• OTHER

No Results Yet

NCT06765317 | RECRUITING | PHASE2

42 participants

A Study of Glofitamab-based Treatment in People With Diffuse Large B-cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-01-16

Completion:

2028-01-31

Conditions

• Diffuse Large B Cell Lymphoma (DLBCL)
• High Grade B Cell Lymphoma

Interventions

• DRUG

No Results Yet

NCT06754046 | RECRUITING | NA

476 participants

BELIEVE Trial: Bulking vErsus sLing for Treating Stress Urinary IncontinEnce at the Time of Vaginal prolapsE Repair (BELIEVE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-05-01

Completion:

2029-04-30

Conditions

• Stress Urinary Incontinence
• Vaginal Prolapse

Interventions

• PROCEDURE
• DEVICE

No Results Yet

NCT06753123 | RECRUITING | NA

10 participants

Be Well at Work-Plus: A Depression and Physical Activity Intervention for Hospital Service Workers (Aim 2)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2026-05-28

Completion:

2026-06-30

Conditions

• Depression
• Physical Inactivity

Interventions

• BEHAVIORAL

No Results Yet

NCT06744920 | RECRUITING | PHASE3

180 participants

A Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib Versus Placebo in Adult Patients With Generalized Myasthenia Gravis

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2025-02-07

Completion:

2028-02-25

Conditions

• Generalized Myasthenia Gravis

Interventions

• DRUG
• OTHER

No Results Yet