Clinical Trials

NCT04992013 | ACTIVE_NOT_RECRUITING | PHASE2

20 participants

Niraparib in Tumors Metastatic to the CNS

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2022-04-05

Completion:

2026-12-01

Conditions

• Metastatic Cancer
• Central Nervous System Cancer

Interventions

• DRUG

No Results Yet

NCT04981834 | SUSPENDED | NA

196 participants

Robot-Assisted Radical Prostatectomy With or Without Vesicopexy in Patients With Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-10-27

Completion:

2027-03-31

Conditions

• Stage I Prostate Cancer AJCC v8
• Stage II Prostate Cancer AJCC v8
• Stage IIA Prostate Cancer AJCC v8
• Stage IIB Prostate Cancer AJCC v8
• Stage IIC Prostate Cancer AJCC v8
• Stage III Prostate Cancer AJCC v8
• Stage IIIA Prostate Cancer AJCC v8
• Stage IIIB Prostate Cancer AJCC v8
• Stage IIIC Prostate Cancer AJCC v8

Interventions

• OTHER
• PROCEDURE

No Results Yet

NCT04977856 | COMPLETED | NA

219 participants

Efficacy and Cost-effectiveness of Internet-delivered CBT for Adolescents With Depression

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-09-10

Completion:

2024-10-14

Conditions

• Major Depressive Disorder

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT04968288 | RECRUITING

195 participants

Natural History of KSHV-Associated Multicentric Castleman s Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-01

Start Date:

2021-11-17

Completion:

2034-01-01

Conditions

• Multicentric Castleman s Disease

No Results Yet

NCT04956770 | COMPLETED | NA

2 participants

Study on Feasibility of Targeted Epidural Spinal Stimulation (TESS) to Improve Mobility in Patients With Parkinson's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-06-14

Completion:

2026-04-16

Conditions

• Parkinson Disease

Interventions

• PROCEDURE

No Results Yet

NCT04939454 | COMPLETED | NA

22 participants

Involvement of Skeletal Muscle Fibrocytes in sarcOpenia in Patients With Chronic ObstRuctive Pulmonary Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2022-11-29

Completion:

2025-11-21

Conditions

• Pulmonary Disease, Chronic Obstructive

Interventions

• PROCEDURE

No Results Yet

NCT04938817 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

110 participants

Safety and Efficacy Study of Investigational Agents as Monotherapy or in Combination With Pembrolizumab (MK-3475) for the Treatment of Extensive-Stage Small Cell Lung Cancer (ES-SCLC) in Need of Second-Line Therapy (MK-3475-B98/KEYNOTE-B98)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-08-19

Completion:

2029-12-10

Conditions

• Small Cell Lung Carcinoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04930991 | TERMINATED | EARLY_PHASE1

25 participants

High Dose Omeprazole in Patients With Pancreatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-09-07

Completion:

2026-03-03

Conditions

• Exocrine Pancreatic Cancer

Interventions

• DRUG

No Results Yet

NCT04928846 | RECRUITING | PHASE3

698 participants

A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2022-03-25

Completion:

2028-03-31

Conditions

• Non Small Cell Lung Cancer

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04902443 | RECRUITING | PHASE1

58 participants

Pomalidomide and Nivolumab in People With Virus-Associated Malignancies With or Without HIV

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-12-10

Completion:

2026-12-01

Conditions

• Viral Associated Malignancies
• Kaposi Sarcoma
• EBV/KSHV-associated Lymphomas

Interventions

• DRUG

No Results Yet

NCT04889430 | COMPLETED | PHASE3

34 participants

Efficacy and Safety of Iptacopan (LNP023) in Adult Patients With Atypical Hemolytic Uremic Syndrome Naive to Complement Inhibitor Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2022-01-17

Completion:

2026-04-11

Conditions

• Atypical Hemolytic Uremic Syndrome

Interventions

• DRUG

No Results Yet

NCT04858269 | ACTIVE_NOT_RECRUITING | PHASE2

32 participants

First Line Weekly Chemo/Immunotherapy for Metastatic Head/Neck Squamous Cell Carcinoma Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-05-27

Completion:

2026-06-30

Conditions

• Head Neck Cancer
• Metastatic Squamous Cell Carcinoma
• Oral Cavity Squamous Cell Carcinoma
• Oropharynx Squamous Cell Carcinoma
• Hypopharynx Squamous Cell Carcinoma
• Larynx Squamous Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT04848025 | RECRUITING | NA

30 participants

Treatment of Central Airway Stenoses Using Computer-Assisted Customized 3d Stents TATUM

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-06-17

Completion:

2029-12-30

Conditions

• Airway Disease

Interventions

• DEVICE

No Results Yet

NCT04847466 | COMPLETED | PHASE2

18 participants

Immunotherapy Combination: Irradiated PD-L1 CAR-NK Cells Plus Pembrolizumab Plus N-803 for Subjects With Recurrent/Metastatic Gastric or Head and Neck Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-12-14

Completion:

2025-12-22

Conditions

• Gastroesophageal Junction (GEJ) Cancers
• Advanced HNSCC

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04833972 | COMPLETED | NA

1531 participants

Eliciting Perceived Norms About Substance Use

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-02-10

Completion:

2022-08-15

Conditions

• Tobacco Use
• Alcohol Drinking

Interventions

• OTHER

No Results Yet

NCT04832243 | COMPLETED | NA

1550 participants

List Experiment to Measure Food and Water Insecurity

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-02-12

Completion:

2022-08-15

Conditions

• Food Deprivation
• Water Deprivation

Interventions

• OTHER

No Results Yet

NCT04825990 | ACTIVE_NOT_RECRUITING | PHASE2

30 participants

Pembrolizumab and Olaparib in Recurrent/Metastatic, Platinum Resistant Nasopharyngeal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2022-03-24

Completion:

2025-11-03

Conditions

• Nasopharyngeal Carcinoma

Interventions

• DRUG

No Results Yet

NCT04819542 | RECRUITING | NA

84 participants

Use of Compression Bandages in the Prevention of Post-mastectomy Lymphoceles

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-08-16

Completion:

2027-11-01

Conditions

• Lymphocele

Interventions

• DEVICE

No Results Yet

NCT04817618 | RECRUITING | PHASE3

98 participants

Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-07-28

Completion:

2027-01-29

Conditions

• C3G

Interventions

• DRUG

No Results Yet

NCT04810624 | RECRUITING | NA

60 participants

Relapse Prevention and Changing Habits in Anorexia Nervosa

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-06-21

Completion:

2027-06-01

Conditions

• Anorexia Nervosa

Interventions

• BEHAVIORAL

No Results Yet

NCT04806646 | ACTIVE_NOT_RECRUITING | PHASE2

21 participants

Tailored Sonidegib Schedule After Complete Response in BCC

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-01-12

Completion:

2024-12-22

Conditions

• Locally Advanced Basal Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT04804384 | RECRUITING | NA

30 participants

Assessment of the Functional Impact of a Close-loop Controlled Prehension Neuroprosthesis in Post-stroke Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-08-30

Completion:

2027-12-30

Conditions

• Stroke

Interventions

• DEVICE

No Results Yet

NCT04800458 | RECRUITING | NA

225 participants

Contribution of Anti-platelet Antibodies Identified With MAIPA Assay in the Demonstration of the Auto-immune Character of a Thrombocytopenia at Diagnosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-05-19

Completion:

2028-05-31

Conditions

• Thrombocytopenia
• Immune Thrombocytopenia
• Myelodysplasia

Interventions

• BIOLOGICAL

No Results Yet

NCT04776395 | RECRUITING | PHASE2

68 participants

Iberdomide Alone or in Combination With Dexamethasone for the Treatment of Intermediate- or High-Risk Smoldering Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-07-09

Completion:

2027-09-01

Conditions

• Smoldering Plasma Cell Myeloma

Interventions

• DRUG
• OTHER

No Results Yet

NCT04771195 | COMPLETED | NA

9941 participants

Social Factors in the Mental Health of Young Adults: Bridging Psychological and Network Analysis

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-08-30

Completion:

2026-05-08

Conditions

• Anxiety
• Depression
• Loneliness
• Stress

Interventions

• BEHAVIORAL

No Results Yet

NCT04770779 | ACTIVE_NOT_RECRUITING | PHASE3

258 participants

A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-11-30

Completion:

2024-04-11

Conditions

• Transfusion-dependent Alpha-Thalassemia
• Transfusion-dependent Beta-Thalassemia

Interventions

• DRUG

Results Available

NCT04770753 | ACTIVE_NOT_RECRUITING | PHASE3

194 participants

A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Non-Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-NTDT)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-12-20

Completion:

2023-11-13

Conditions

• Non-Transfusion-dependent Alpha-Thalassemia
• Non-Transfusion-dependent Beta-Thalassemia

Interventions

• DRUG

Results Available

NCT04769193 | COMPLETED | NA

35 participants

A Clinical Trial Evaluating the Efficacy of a Skin Cream in Improving Facial Appearance and Skin Elasticity

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-01-27

Completion:

2022-11-27

Conditions

• Atrophy, Hemifacial
• Elastosis
• Photoaging

Interventions

• OTHER

No Results Yet

NCT04758650 | TERMINATED | PHASE2

29 participants

Study of 68GaNOTA-Anti-MMR-VHH2 in Oncological Lesions, Cardiovascular Atherosclerosis, Syndrome With Abnormal Immune Activation and sarcoïdosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-01-26

Completion:

2025-01-08

Conditions

• Solid Malignancy Located in the Head and Neck
• Cancer
• Carotid Stenosis
• Atherosclerosis of Artery
• Hodgkin Lymphoma, Adult
• Non Hodgkin Lymphoma
• HLH
• Cardiac Sarcoidosis
• Sarcoidosis

Interventions

• DRUG

No Results Yet

NCT04757168 | COMPLETED | NA

10 participants

Changes in Regional and Global Cardiac Contractility After Stimulation in Scar Zone With the NOGA System

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2022-02-23

Completion:

2024-01-26

Conditions

• Myocardial Infarction

Interventions

• DEVICE

No Results Yet

NCT04755205 | RECRUITING

525 participants

A Natural History Study of Children and Adults With Olfactory Neuroblastoma

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-01

Start Date:

2022-06-02

Completion:

2029-12-31

Conditions

• Olfactory Neuroblastoma
• Esthesioneuroblastoma

No Results Yet

NCT04753879 | ACTIVE_NOT_RECRUITING | PHASE2

38 participants

Multi-agent Low Dose Chemotherapy GAX-CI Followed by Olaparib and Pembro in Metastatic Pancreatic Ductal Cancer.

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-09-29

Completion:

2026-12-01

Conditions

• Metastatic Pancreatic Cancer

Interventions

• DRUG

No Results Yet

NCT04750226 | COMPLETED | PHASE3

118 participants

Study To Assess Adverse Events and Change in Disease Activity Of 24-hour Continuous Subcutaneous Infusion Of ABBV-951 In Adult Participants With Advanced Parkinson's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-02-18

Completion:

2026-04-27

Conditions

• Parkinson's Disease (PD)

Interventions

• DRUG

No Results Yet

NCT04747353 | COMPLETED | NA

23 participants

Computed Tomography Targets for Efficient Guidance of Catheter Ablation in Ventricular Tachycardia (MAP-IN-HEART)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-05-04

Completion:

2022-11-21

Conditions

• Ventricular Tachycardia

Interventions

• DEVICE

No Results Yet

NCT04746183 | RECRUITING | PHASE1/PHASE2

600 participants

AGILE (Early Phase Platform Trial for COVID-19)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2020-07-03

Completion:

2027-03-31

Conditions

• Covid19

Interventions

• DRUG

No Results Yet

NCT04745221 | RECRUITING | NA

100 participants

Efficacy and Safety of Auto-FMT in Preventing aGVHD

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-03-01

Completion:

2027-03-01

Conditions

• Graft Versus Host Disease, Acute

Interventions

• OTHER

No Results Yet

NCT04742010 | COMPLETED | PHASE2

59 participants

Zoledronic Acid for Prevention of Bone Loss After BAriatric Surgery (ZABAS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-02-20

Completion:

2023-11-01

Conditions

• Bone Loss
• Muscle Atrophy
• Bariatric Surgery

Interventions

• DRUG

No Results Yet

NCT04739813 | ACTIVE_NOT_RECRUITING | PHASE1

34 participants

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid in Combination With Polatuzumab (ViPOR-P) in Relapsed/Refractory B-cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-07-09

Completion:

2026-05-07

Conditions

• Lymphoma
• Non-Hodgkin Lymphoma
• Diffuse Large B-Cell Lymphoma
• Burkitt Lymphoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04737720 | COMPLETED

1 participants

Intravenous ACP-501 for Familial LCAT Deficiency (rhLCAT)

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-01

Start Date:

2013-01-24

Completion:

2013-12-12

Conditions

• Familial LCAT Deficiency

Interventions

• DRUG

No Results Yet

NCT04736173 | ACTIVE_NOT_RECRUITING | PHASE2

169 participants

Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-01

Start Date:

2021-02-08

Completion:

2027-05-31

Conditions

• Non Small Cell Lung Cancer
• Nonsquamous Non Small Cell Lung Cancer
• Squamous Non Small Cell Lung Cancer
• Lung Cancer

Interventions

• DRUG

No Results Yet