Clinical Trials

NCT03632239 | ENROLLING_BY_INVITATION

1000 participants

Reverse Phenotyping Core

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-01-23
Completion:: 2028-06-01

Conditions

Harboring of Unexpected Genetic Variant

No Results Yet

NCT03630289 | COMPLETED | NA

12 participants

Surgical Tissue Flap to Bypass the Blood Brain Barrier in GBM

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2018-07-27
Completion:: 2023-05-15

Conditions

Glioblastoma
Glioblastoma Multiforme
GBM
Brain Cancer

Interventions

PROCEDURE

No Results Yet

NCT03600350 | ACTIVE_NOT_RECRUITING | PHASE2

19 participants

pTVG-HP and Nivolumab in Patients With Non-Metastatic PSA-Recurrent Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2018-09-10
Completion:: 2022-11-07

Conditions

Prostate Cancer

Interventions

BIOLOGICAL
DRUG

Results Available

NCT03568266 | RECRUITING

500 participants

Pharmacogenomics of Asparaginase Induced Hepatotoxicity

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2018-05-22
Completion:: 2026-12-31

Conditions

Acute Lymphoblastic Leukemia

Interventions

PROCEDURE

No Results Yet

NCT03559686 | NO_LONGER_AVAILABLE

Named Patient Program With Certolizumab Pegol in Adults Suffering From Rheumatoid Aarthritis (RA)

Study Type:: EXPANDED_ACCESS
Last Updated:: 2026-06-01

Conditions

Rheumatoid Arthritis

Interventions

DRUG

No Results Yet

NCT03532516 | NO_LONGER_AVAILABLE

Compassionate Use Program With Brivaracetam for the Treatment of Patients With Epilepsy

Study Type:: EXPANDED_ACCESS
Last Updated:: 2026-06-01

Conditions

Epilepsy

Interventions

DRUG

No Results Yet

NCT03532464 | COMPLETED | PHASE4

460 participants

Azithromycin Compared With Doxycycline for Treating Anorectal Chlamydia Trachomatis Infection Concomitant to a Vaginal Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2018-10-10
Completion:: 2020-08-17

Conditions

Chlamydia Trachomatis Infection
Vaginal Infection
Anal Infection

Interventions

DRUG

No Results Yet

NCT03520660 | ACTIVE_NOT_RECRUITING | PHASE4

121 participants

People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral Agents

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2018-10-19
Completion:: 2032-12-31

Conditions

Diabetes Mellitus
Hepatitis C, Chronic
Cardiovascular Diseases

Interventions

DRUG

No Results Yet

NCT03486873 | RECRUITING | PHASE3

3500 participants

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2018-08-21
Completion:: 2043-08-04

Conditions

Solid Tumors
Hematologic Malignancies

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT03467516 | ACTIVE_NOT_RECRUITING | PHASE2

34 participants

Adoptive Transfer of Tumor Infiltrating Lymphocytes for Metastatic Uveal Melanoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2018-05-14
Completion:: 2027-07-31

Conditions

Uveal Neoplasms
Melanoma, Uveal

Interventions

BIOLOGICAL

No Results Yet

NCT03458936 | ACTIVE_NOT_RECRUITING

1500 participants

Resilience in Adolescent Development

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2016-08-17
Completion:: 2031-12-31

Conditions

Risk Assessment
Resilience, Psychological
Depression
Mood Disorders
Anxiety Disorders
Mental Health

No Results Yet

NCT03407066 | RECRUITING

10200 participants

Perception, Sensation, Cognition and Action in Humans

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2019-03-26
Completion:: 2027-12-31

Conditions

Normal Physiology

No Results Yet

NCT03394066 | RECRUITING | NA

70 participants

Mechanism of Non-invasive Magnetic Stimulation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2018-09-19
Completion:: 2026-12-31

Conditions

Healthy Volunteers

Interventions

DEVICE

No Results Yet

NCT03370406 | RECRUITING | PHASE1

30 participants

Intralesional 5-Fluorouracil (5FU), Topical Calcipotriene Treatment for SCC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2018-08-03
Completion:: 2027-09-30

Conditions

Carcinoma, Squamous Cell

Interventions

DRUG

No Results Yet

NCT03366116 | RECRUITING | PHASE1

65 participants

5-aza-4'-Thio-2'-Deoxycytidine (Aza-TdC) in People With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2018-11-05
Completion:: 2026-09-30

Conditions

Neoplasms
Solid Tumors

Interventions

DRUG

No Results Yet

NCT03358303 | ACTIVE_NOT_RECRUITING | NA

90 participants

Effects of Telemonitoring on the Outcome of Heart Failure Patients After an Incidence of Acute Decompensation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2018-11-16
Completion:: 2023-09-01

Conditions

Heart Failure

Interventions

DEVICE

No Results Yet

NCT03331601 | TERMINATED | PHASE2

7 participants

Evaluation of 68-GaNOTA-Anti-HER2 VHH1 Uptake in Brain Metastasis of Cancer Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2017-10-16
Completion:: 2025-10-14

Conditions

Carcinoma
Receptor, ErbB-2

Interventions

DRUG

No Results Yet

NCT03330821 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

53 participants

Pevonedistat, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2018-04-18
Completion:: 2026-12-31

Conditions

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
Acute Myeloid Leukemia With Myelodysplasia-Related Changes
Therapy-Related Acute Myeloid Leukemia

Interventions

DRUG
OTHER

No Results Yet

NCT03319901 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

82 participants

Venetoclax and Chemotherapy as Frontline Therapy in Older Patients and Patients With Relapsed/Refractory ALL

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2017-10-30
Completion:: 2025-11-25

Conditions

Leukemia

Interventions

DRUG

No Results Yet

NCT03294460 | RECRUITING | PHASE1

128 participants

Nicotinic Receptor Genetic Variation and Alcohol Reward

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2019-06-10
Completion:: 2026-12-31

Conditions

Alcohol Drinking

Interventions

DRUG

No Results Yet

NCT03287596 | COMPLETED | NA

121 participants

Cartography and Quantitative Characterization of Achilles Tendon Fibrocartilage by TE = 0ms Imaging at 3T MRI

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2018-04-07
Completion:: 2023-01-21

Conditions

Spondyloarthropathy
Tendinopathy

Interventions

DEVICE

No Results Yet

NCT03257761 | ACTIVE_NOT_RECRUITING | PHASE1

55 participants

Guadecitabine and Durvalumab in Treating Patients With Advanced Liver, Pancreatic, Bile Duct, or Gallbladder Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2018-02-07
Completion:: 2021-09-27

Conditions

Extrahepatic Bile Duct Adenocarcinoma, Biliary Type
Gallbladder Adenocarcinoma, Biliary Type
Metastatic Pancreatic Adenocarcinoma
Recurrent Cholangiocarcinoma
Recurrent Gallbladder Carcinoma
Recurrent Hepatocellular Carcinoma
Recurrent Intrahepatic Cholangiocarcinoma
Recurrent Pancreatic Carcinoma
Stage III Gallbladder Cancer AJCC V7
Stage III Hepatocellular Carcinoma AJCC v7
Stage III Intrahepatic Cholangiocarcinoma AJCC v7
Stage III Pancreatic Cancer AJCC v6 and v7
Stage IIIA Gallbladder Cancer AJCC v7
Stage IIIA Hepatocellular Carcinoma AJCC v7
Stage IIIB Gallbladder Cancer AJCC v7
Stage IIIB Hepatocellular Carcinoma AJCC v7
Stage IIIC Hepatocellular Carcinoma AJCC v7
Stage IV Gallbladder Cancer AJCC v7
Stage IV Hepatocellular Carcinoma AJCC v7
Stage IV Pancreatic Cancer AJCC v6 and v7
Stage IVA Gallbladder Cancer AJCC v7
Stage IVA Hepatocellular Carcinoma AJCC v7
Stage IVA Intrahepatic Cholangiocarcinoma AJCC v7
Stage IVB Gallbladder Cancer AJCC v7
Stage IVB Hepatocellular Carcinoma AJCC v7
Stage IVB Intrahepatic Cholangiocarcinoma AJCC v7
Unresectable Gallbladder Carcinoma
Unresectable Pancreatic Carcinoma

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT03225144 | RECRUITING

360 participants

Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2017-10-11
Completion:: 2027-10-30

Conditions

Frontotemporal Dementia
Amyotrophic Lateral Sclerosis
Progressive Supranuclear Palsy

No Results Yet

NCT03223610 | RECRUITING | PHASE1/PHASE2

155 participants

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2018-02-09
Completion:: 2026-12-01

Conditions

Lymphoma
Non-Hodgkin Lymphoma
Diffuse Large B-Cell Lymphoma
Burkitt Lymphoma

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT03213704 | ACTIVE_NOT_RECRUITING | PHASE2

9 participants

Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2017-08-23
Completion:: 2024-09-30

Conditions

Advanced Malignant Solid Neoplasm
Recurrent Ependymoma
Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
Recurrent Glioma
Recurrent Hepatoblastoma
Recurrent Kidney Wilms Tumor
Recurrent Langerhans Cell Histiocytosis
Recurrent Malignant Germ Cell Tumor
Recurrent Malignant Glioma
Recurrent Malignant Solid Neoplasm
Recurrent Medulloblastoma
Recurrent Neuroblastoma
Recurrent Non-Hodgkin Lymphoma
Recurrent Osteosarcoma
Recurrent Rhabdoid Tumor
Recurrent Rhabdomyosarcoma
Recurrent Soft Tissue Sarcoma
Refractory Ependymoma
Refractory Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
Refractory Glioma
Refractory Hepatoblastoma
Refractory Langerhans Cell Histiocytosis
Refractory Malignant Germ Cell Tumor
Refractory Malignant Glioma
Refractory Malignant Solid Neoplasm
Refractory Medulloblastoma
Refractory Neuroblastoma
Refractory Non-Hodgkin Lymphoma
Refractory Osteosarcoma
Refractory Primary Central Nervous System Neoplasm
Refractory Rhabdoid Tumor
Refractory Rhabdomyosarcoma
Refractory Soft Tissue Sarcoma

Interventions

PROCEDURE
DRUG

Results Available

NCT03213002 | RECRUITING | PHASE1/PHASE2

67 participants

Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2017-06-13
Completion:: 2028-06-30

Conditions

Glioblastoma Multiforme (GBM)
Glioblastoma
Glioma of Brain
Glioblastoma, Adult
Brain Tumor
Brain Tumor, Primary
Brain Tumor Adult
Cancer
Brain Cancer

Interventions

DRUG

No Results Yet

NCT03210714 | ACTIVE_NOT_RECRUITING | PHASE2

20 participants

Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2018-06-05
Completion:: 2023-09-30

Conditions

Advanced Malignant Solid Neoplasm
Recurrent Childhood Ependymoma
Recurrent Childhood Malignant Germ Cell Tumor
Recurrent Childhood Medulloblastoma
Recurrent Childhood Non-Hodgkin Lymphoma
Recurrent Childhood Osteosarcoma
Recurrent Childhood Rhabdomyosarcoma
Recurrent Childhood Soft Tissue Sarcoma
Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
Recurrent Hepatoblastoma
Recurrent Langerhans Cell Histiocytosis
Recurrent Malignant Glioma
Recurrent Malignant Solid Neoplasm
Recurrent Neuroblastoma
Recurrent Primary Central Nervous System Neoplasm
Recurrent Rhabdoid Tumor
Refractory Childhood Malignant Germ Cell Tumor
Refractory Childhood Osteosarcoma
Refractory Childhood Rhabdomyosarcoma
Refractory Childhood Soft Tissue Sarcoma
Refractory Ependymoma
Refractory Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
Refractory Hepatoblastoma
Refractory Langerhans Cell Histiocytosis
Refractory Malignant Glioma
Refractory Malignant Solid Neoplasm
Refractory Medulloblastoma
Refractory Neuroblastoma
Refractory Non-Hodgkin Lymphoma
Refractory Primary Central Nervous System Neoplasm
Refractory Rhabdoid Tumor
Wilms Tumor

Interventions

PROCEDURE
DRUG
OTHER

Results Available

NCT03206099 | RECRUITING

20000 participants

NIAID Centralized Sequencing Protocol

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2017-07-31
Completion:: 2029-12-31

Conditions

Atopy
Primary Immunodeficiency
Autoimmunity
Autoinflammation

No Results Yet

NCT03190928 | RECRUITING

200 participants

Clonal Evolution in Follicular Lymphoma

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2017-07-27
Completion:: 2029-01-01

Conditions

Follicular Lymphoma

No Results Yet

NCT03186820 | COMPLETED | NA

74 participants

Exploratory Study of the Interest of MRI Susceptibility Weighted Imaging for the Pre-operative Assessment of Pelvic Endometriosis Extent

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2017-06-19
Completion:: 2018-04-24

Conditions

Endometriosis

Interventions

OTHER

No Results Yet

NCT03177018 | COMPLETED | NA

34 participants

DNA Analysis From Isolated Cardiomyocytes in the Molecular Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2016-09-13
Completion:: 2018-02-23

Conditions

Arrhythmogenic Right Ventricular Dysplasia
Arrhythmogenic Right Ventricular Cardiomyopathy

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT03155620 | ACTIVE_NOT_RECRUITING | PHASE2

1377 participants

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2017-07-31
Completion:: 2025-03-31

Conditions

Advanced Malignant Solid Neoplasm
Ann Arbor Stage III Non-Hodgkin Lymphoma
Ann Arbor Stage IV Non-Hodgkin Lymphoma
Histiocytic Sarcoma
Juvenile Xanthogranuloma
Langerhans Cell Histiocytosis
Malignant Glioma
Recurrent Childhood Rhabdomyosarcoma
Recurrent Ependymoma
Recurrent Ewing Sarcoma
Recurrent Glioma
Recurrent Hepatoblastoma
Recurrent Langerhans Cell Histiocytosis
Recurrent Malignant Germ Cell Tumor
Recurrent Malignant Solid Neoplasm
Recurrent Medulloblastoma
Recurrent Neuroblastoma
Recurrent Non-Hodgkin Lymphoma
Recurrent Osteosarcoma
Recurrent Peripheral Primitive Neuroectodermal Tumor
Recurrent Primary Central Nervous System Neoplasm
Recurrent Rhabdoid Tumor
Recurrent Soft Tissue Sarcoma
Refractory Ewing Sarcoma
Refractory Glioma
Refractory Hepatoblastoma
Refractory Langerhans Cell Histiocytosis
Refractory Malignant Germ Cell Tumor
Refractory Malignant Solid Neoplasm
Refractory Medulloblastoma
Refractory Neuroblastoma
Refractory Non-Hodgkin Lymphoma
Refractory Osteosarcoma
Refractory Peripheral Primitive Neuroectodermal Tumor
Refractory Primary Central Nervous System Neoplasm
Refractory Rhabdoid Tumor
Refractory Rhabdomyosarcoma
Rhabdoid Tumor
Stage III Osteosarcoma AJCC v7
Stage III Soft Tissue Sarcoma AJCC v7
Stage IV Osteosarcoma AJCC v7
Stage IV Soft Tissue Sarcoma AJCC v7
Stage IVA Osteosarcoma AJCC v7
Stage IVB Osteosarcoma AJCC v7
Wilms Tumor

Interventions

PROCEDURE
DRUG
OTHER

Results Available

NCT03148743 | RECRUITING

50 participants

FMT in Gut aGVHD Treated

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2017-05-16
Completion:: 2028-12-01

Conditions

Acute-graft-versus-host Disease

Interventions

BIOLOGICAL

No Results Yet

NCT03111745 | COMPLETED

730 participants

Retrospective Study of Viral Reactivation Across All Bone Marrow Transplant Protocols Since 2010

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2017-04-13
Completion:: 2018-12-29

Conditions

Viral Infections

No Results Yet

NCT03092505 | COMPLETED

190 participants

Herpesviruses Reactivation In Hiv-Infected Women Initiating ART (HERA)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2018-06-15
Completion:: 2021-02-01

Conditions

Herpes Virus-Related Illnesses

No Results Yet

NCT03078218 | COMPLETED | NA

44140 participants

Health-economic Impact of Pulse Oximetry Systematic Screening of Critical Congenital Heart Disease in Asymptomatic Newborns

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2017-03-01
Completion:: 2020-01-07

Conditions

Critical Congenital Heart Disease

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT03049462 | RECRUITING | PHASE1

100 participants

The Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment With Beta3-Adrenergic Receptor Agonists

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2017-03-13
Completion:: 2026-09-30

Conditions

Polycystic Ovary Syndrome

Interventions

DRUG
OTHER

No Results Yet

NCT03022851 | COMPLETED | NA

32 participants

The Prophet Trial -Pilot Study to Assess Safety and Efficacy of a Novel Atrial Flow Regulator (AFR) in Patients With Pulmonary Hypertension

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2017-07-19
Completion:: 2024-01-08

Conditions

Pulmonary Hypertension

Interventions

DEVICE

No Results Yet

NCT03012321 | ACTIVE_NOT_RECRUITING | PHASE2

70 participants

Abiraterone/Prednisone, Olaparib, or Abiraterone/Prednisone + Olaparib in Patients With Metastatic Castration-Resistant Prostate Cancer With DNA Repair Defects

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2017-01-12
Completion:: 2023-10-21

Conditions

Prostate Cancer Metastatic Castration-Resistant
Abnormal DNA Repair
Metastatic Prostate Carcinoma
Stage IV Prostate Cancer

Interventions

DRUG

No Results Yet

NCT03000244 | RECRUITING

2000 participants

Long-Term Follow-up of People Undergoing Hematopoietic Stem Cell Transplantation

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2017-04-26
Completion:: 2050-08-12

Conditions

Hematopoietic Stem Cell Transplantation
Tissue Donors

No Results Yet