Clinical Trials

NCT05566756 | COMPLETED

307 participants

Study Evaluating Kesimpta® Treatment Effects in Patients With Relapsing Multiple Sclerosis Transitioning From Other Therapies

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2022-10-28

Completion:

2025-05-28

Conditions

• Multiple Sclerosis

Interventions

• OTHER

No Results Yet

NCT05564377 | RECRUITING | PHASE2

2900 participants

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2023-04-07

Completion:

2030-07-01

Conditions

• Advanced Malignant Solid Neoplasm
• Anatomic Stage III Breast Cancer AJCC v8
• Anatomic Stage IV Breast Cancer AJCC v8
• Locally Advanced Malignant Solid Neoplasm
• Malignant Female Reproductive System Neoplasm
• Metastatic HER2-Negative Breast Carcinoma
• Metastatic Malignant Solid Neoplasm
• Recurrent Endometrial Carcinoma
• Recurrent Fallopian Tube Carcinoma
• Recurrent Malignant Female Reproductive System Neoplasm
• Recurrent Malignant Solid Neoplasm
• Recurrent Ovarian Carcinoma
• Recurrent Primary Peritoneal Carcinoma
• Unresectable HER2-Negative Breast Carcinoma
• Unresectable Malignant Solid Neoplasm

Interventions

• DRUG
• PROCEDURE
• BIOLOGICAL

No Results Yet

NCT05546801 | COMPLETED | NA

46 participants

Antenatal Ultrasound Diagnosis of Periventricular Pseudocysts and Postnatal Outcome

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-10-12

Completion:

2022-12-01

Conditions

• Periventricular Pseudocysts

Interventions

• OTHER

No Results Yet

NCT05529927 | RECRUITING | PHASE2

204 participants

Efficacy and Safety of Sustained-release Dexamphetamine in Patients With Moderate to Severe Cocaine Use Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2026-04-22

Completion:

2029-01-31

Conditions

• Cocaine Use Disorder

Interventions

• DRUG

No Results Yet

NCT05515406 | TERMINATED | PHASE1

9 participants

A Study to Investigate the Safety, Tolerability, PK, PD, and Efficacy of ONO-7018 in Patients With R/R NHL or CLL

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2023-02-13

Completion:

2025-08-13

Conditions

• Lymphoma, Non-Hodgkin
• Leukemia, Lymphocytic, Chronic, B-Cell

Interventions

• DRUG

No Results Yet

NCT05503030 | COMPLETED

88 participants

Correlation Between Changes in Lung Function and Changes in Cough and Dyspnoea in Nintedanib-treated Connective Tissue Disease Interstitial Lung Disease (CTD-ILD) Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2022-12-21

Completion:

2026-05-13

Conditions

• Lung Diseases, Interstitial

Interventions

• DRUG

No Results Yet

NCT05501366 | ACTIVE_NOT_RECRUITING | NA

14 participants

Strategies to Augment Ketosis: Optimization of Ketone Delivery Strategies

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2023-06-05

Completion:

2026-10-31

Conditions

• Ketosis

Interventions

• RADIATION
• OTHER
• DIETARY_SUPPLEMENT
• BEHAVIORAL
• BIOLOGICAL

No Results Yet

NCT05500573 | RECRUITING | NA

2000 participants

Sex Selection of Human Spermatozoa

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2013-11-06

Completion:

2028-12-31

Conditions

• Infertility
• IVF

Interventions

• PROCEDURE

No Results Yet

NCT05492721 | COMPLETED | PHASE3

180 participants

Comparing Tissue Adhesives in Port Site Closure

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-06-29

Completion:

2025-06-23

Conditions

• Dermatitis, Contact

Interventions

• DEVICE

Results Available

NCT05490446 | ACTIVE_NOT_RECRUITING | PHASE2

87 participants

A Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-Risk Myelodysplastic Syndromes (LR-MDS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-11-07

Completion:

2026-03-17

Conditions

• Myelodysplastic Syndromes

Interventions

• DRUG

No Results Yet

NCT05480618 | COMPLETED | NA

17 participants

Slow Yogic-Derived Breathing and Respiration and Cardiovascular Variability in Spinal Cord Injury Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-08-22

Completion:

2024-01-20

Conditions

• Spinal Cord Injuries
• Slow Breathing

Interventions

• BEHAVIORAL

Results Available

NCT05462574 | RECRUITING

75 participants

Right Ventricle Lipid in Pulmonary Arterial Hypertension (PAH)

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2023-01-17

Completion:

2027-09-30

Conditions

• Idiopathic Pulmonary Arterial Hypertension
• Heritable Pulmonary Arterial Hypertension
• Pulmonary Arterial Hypertension Associated With Connective Tissue Disease

Interventions

• OTHER

No Results Yet

NCT05462106 | RECRUITING | PHASE1/PHASE2

304 participants

A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-06-21

Completion:

2029-04-30

Conditions

• Amyloid Plaque
• Beta-Amyloid
• DSAD
• Prodromal Alzheimer's Disease
• Alzheimer's Disease

Interventions

• BIOLOGICAL

No Results Yet

NCT05461495 | ACTIVE_NOT_RECRUITING | NA

300 participants

NYUCI-ES: Psychosocial Intervention to Improve Health Outcomes for Chinese and Korean ADRD Caregivers

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2023-02-01

Completion:

2026-10-30

Conditions

• Dementia Caregivers
• Diabetes
• Heart Disease
• Overweight

Interventions

• BEHAVIORAL

No Results Yet

NCT05460676 | COMPLETED | NA

43 participants

Reducing Tobacco Smoking: a Transcranial Direct Current Stimulation (TDCS) Telehealth Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2023-08-15

Completion:

2026-01-22

Conditions

• Smoking Cessation

Interventions

• DEVICE
• OTHER

No Results Yet

NCT05458934 | RECRUITING

5000 participants

Analysis of Exhaled Breath From Patients With Lung-/Airway Diseases (BigExBrESs)

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2021-05-11

Completion:

2030-05-31

Conditions

• Lung-/Airway Diseases

Interventions

• OTHER

No Results Yet

NCT05458297 | ACTIVE_NOT_RECRUITING | PHASE2

189 participants

A Study of Zilovertamab Vedotin (MK-2140) as Monotherapy and in Combination in Participants With Aggressive and Indolent B-cell Malignancies (MK-2140-006)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-07-21

Completion:

2029-05-17

Conditions

• Chronic Lymphocytic Leukemia
• Mantle Cell Lymphoma
• Follicular Lymphoma
• Richter Transformation Lymphoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT05456009 | RECRUITING

1500 participants

Exhaled Breath Analysis in Human Subjects

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2019-02-19

Completion:

2030-03-01

Conditions

• Exhaled Breath Pattern After Medication Intake, in OSA Patients, or Other Pulmonary Diseases

Interventions

• OTHER

No Results Yet

NCT05452226 | COMPLETED | NA

7 participants

Neuromuscular Electrical Stimulation in COPD/Community Acquired Pneumonia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-07-12

Completion:

2025-12-01

Conditions

• Community-acquired Pneumonia
• COPD Exacerbation Acute

Interventions

• DEVICE

No Results Yet

NCT05434104 | RECRUITING | NA

114 participants

The LISA (Lactoferrin InStead of Antibiotics/Antifungals) Feasibility Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2026-04-16

Completion:

2027-12-31

Conditions

• Bacterial Vaginosis
• Candida Vaginal

Interventions

• OTHER
• DRUG

No Results Yet

NCT05418790 | WITHDRAWN | NA

0 participants

A Pilot Study to Evaluate Alternative Viral Load Tests During Start of Antiretroviral Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-06-01

Completion:

2022-06-02

Conditions

• HIV-1-infection

Interventions

• DEVICE

No Results Yet

NCT05418088 | RECRUITING | PHASE1

54 participants

Genetically Engineered Cells (Anti-CD19/CD20/CD22 CAR T-cells) for the Treatment of Relapsed or Refractory Lymphoid Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-06-30

Completion:

2027-07-01

Conditions

• Recurrent Acute Lymphoblastic Leukemia
• Recurrent B Acute Lymphoblastic Leukemia
• Recurrent B-Cell Prolymphocytic Leukemia
• Recurrent Chronic Lymphocytic Leukemia
• Recurrent High Grade B-Cell Lymphoma
• Recurrent Indolent Non-Hodgkin Lymphoma
• Recurrent Non-Hodgkin Lymphoma
• Recurrent Transformed Chronic Lymphocytic Leukemia
• Refractory Acute Lymphoblastic Leukemia
• Refractory B Acute Lymphoblastic Leukemia
• Refractory B-Cell Prolymphocytic Leukemia
• Refractory Chronic Lymphocytic Leukemia
• Refractory High Grade B-Cell Lymphoma
• Refractory Indolent Non-Hodgkin Lymphoma
• Refractory Non-Hodgkin Lymphoma
• Refractory Transformed Chronic Lymphocytic Leukemia
• Refactory Childhood Acute Lymphoblastic Leukemia
• Refractory Childhood Non-Hodgkin Lymphoma

Interventions

• BIOLOGICAL
• DRUG
• PROCEDURE

No Results Yet

NCT05413915 | TERMINATED | PHASE3

8 participants

Asciminib Used in Consolidation With Imatinib vs. Imatinib to Achieve TFR in CP-CML

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2023-11-01

Completion:

2025-07-02

Conditions

• Chronic Myeloid Leukemia
• Chronic Myeloid Leukemia, BCR/ABL-Positive
• Chronic Myeloid Leukemia in Remission

Interventions

• DRUG

No Results Yet

NCT05411094 | SUSPENDED | PHASE1

18 participants

Testing the Safety of the Anti-Cancer Drugs Durvalumab and Olaparib During Radiation Therapy for Locally Advanced Unresectable Pancreatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2023-05-22

Completion:

2026-07-01

Conditions

• Locally Advanced Pancreatic Carcinoma
• Stage II Pancreatic Cancer AJCC v8
• Stage III Pancreatic Cancer AJCC v8
• Unresectable Pancreatic Carcinoma

Interventions

• PROCEDURE
• BIOLOGICAL
• DRUG

No Results Yet

NCT05400252 | ACTIVE_NOT_RECRUITING | NA

238 participants

Whole Health in VA Mental Health: Omnis Salutis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2023-02-01

Completion:

2026-10-31

Conditions

• Stress Disorders, Post-Traumatic
• Depressive Disorder
• Anxiety Disorders
• Substance-Related Disorders

Interventions

• BEHAVIORAL

No Results Yet

NCT05391828 | RECRUITING | NA

200 participants

Persona MC vs PS RCT With ROSA

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2023-09-27

Completion:

2026-12-31

Conditions

• Total Knee Arthroplasty

Interventions

• DEVICE

No Results Yet

NCT05376254 | RECRUITING

200 participants

3D Assessment of RV Function in Patients Undergoing LVAD Implantation

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2022-03-22

Completion:

2027-01-19

Conditions

• Heart Failure

No Results Yet

NCT05363176 | COMPLETED | NA

300 participants

Treatment, Pain, and Opioids

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-06-01

Completion:

2025-03-25

Conditions

• Chronic Pain

Interventions

• BEHAVIORAL

Results Available

NCT05362370 | ACTIVE_NOT_RECRUITING

99 participants

Stryker PEEK Customized Implant: A Prospective Post Market Follow Up to Evaluate Safety, Performance and Effectiveness

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2023-02-01

Completion:

2026-11-30

Conditions

• Cranioplasty
• Craniofacial Abnormalities
• Craniofacial Injuries

Interventions

• DEVICE

No Results Yet

NCT05361421 | ACTIVE_NOT_RECRUITING | PHASE4

1200 participants

Effect of Intensive LDL-cholesterol Targeting for Elderly Patients With Cardiovascular Disease: I-OLD Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-07-19

Completion:

2027-10-15

Conditions

• Cardiovascular Disease

Interventions

• DRUG

No Results Yet

NCT05348785 | COMPLETED | PHASE2

650 participants

A Study to Learn About the Safety of BIIB122 Tablets and Whether They Can Slow the Worsening of Early-Stage Parkinson's Disease in Adults Between the Ages of 30 and 80

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-04-19

Completion:

2026-03-09

Conditions

• Parkinson Disease

Interventions

• DRUG

No Results Yet

NCT05341661 | ACTIVE_NOT_RECRUITING | NA

245 participants

Butterfly Pivotal Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-04-07

Completion:

2025-12-31

Conditions

• BPH (Benign Prostatic Hyperplasia)
• Lower Urinary Tract Symptoms (LUTS)

Interventions

• DEVICE

No Results Yet

NCT05331183 | ACTIVE_NOT_RECRUITING | PHASE3

297 participants

Study to Evaluate Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) Long-term Safety and Efficacy in Subjects Without F508del

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-11-23

Completion:

2027-04-06

Conditions

• Cystic Fibrosis

Interventions

• DRUG

No Results Yet

NCT05329441 | RECRUITING

160 participants

Inflammatory and Glutamatergic Mechanisms of Sustained Threat in Adolescents With Depression

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2023-07-06

Completion:

2028-04-01

Conditions

• Depression in Adolescence

Interventions

• BEHAVIORAL

No Results Yet

NCT05321134 | RECRUITING | NA

25 participants

Evaluation of SINGLE PORT (SP) Robotic Technology in Colorectal Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-04-28

Completion:

2028-04-30

Conditions

• Colo-rectal Cancer
• Rectal Prolapse
• Colostomy Stoma
• Colorectal Disorders

Interventions

• DEVICE

No Results Yet

NCT05309616 | COMPLETED | PHASE2

10 participants

Effects of Interleukin (IL)-17A Inhibition on Idiopathic Subglottic Stenosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2025-02-20

Completion:

2026-05-19

Conditions

• Idiopathic Subglottic Stenosis

Interventions

• DRUG

No Results Yet

NCT05296096 | COMPLETED | NA

18 participants

PRotein Optimization With eXercise to Improve MUscle Mass and Functional outcomeS

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2023-02-20

Completion:

2025-12-01

Conditions

• Muscle Loss
• Protein
• Mobility
• Pediatric ALL

Interventions

• OTHER

No Results Yet

NCT05292274 | ACTIVE_NOT_RECRUITING

304 participants

NIH RECOVER Tissue Pathology: Understanding the Long-Term Impact of COVID-19

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2022-03-30

Completion:

2026-01-30

Conditions

• COVID-19
• SARS CoV 2 Infection

No Results Yet

NCT05289167 | RECRUITING | PHASE1/PHASE2

74 participants

Post-Transplant Cyclophosphamide, Bortezomib and Abatacept for the Prevention of Graft-versus-Host-Disease (GvHD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-03-13

Completion:

2026-08-31

Conditions

• Graft-versus-host Disease

Interventions

• DRUG

No Results Yet

NCT05268042 | ACTIVE_NOT_RECRUITING | NA

80 participants

Moderately Carbohydrate-restricted Diet to Treat NAFLD in Adolescents

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-05-01

Completion:

2026-07-06

Conditions

• Non-Alcoholic Fatty Liver Disease
• Obesity

Interventions

• OTHER

No Results Yet