Clinical Trials

NCT05262855 | COMPLETED | PHASE2

63 participants

Study of [68Ga]FAPI-46 PET in Patients With Pancreatic Ductal Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-05-02

Completion:

2025-03-07

Conditions

• FAP
• PDAC - Pancreatic Ductal Adenocarcinoma

Interventions

• DRUG

Results Available

NCT05256940 | ACTIVE_NOT_RECRUITING | NA

368 participants

Motivational Interviewing to Address Suicidal Ideation for Veterans at High Risk for Suicide

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-11-30

Completion:

2026-03-31

Conditions

• Suicide, Attempted
• Suicidal Ideation

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT05228184 | TERMINATED | PHASE4

34 participants

Use of Tirosint®-SOL or Tablet Formulations of Levothyroxine in Pediatric Patients With Congenital Hypothyroidism (CH)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-01-21

Completion:

2025-03-27

Conditions

• Congenital Hypothyroidism

Interventions

• DRUG

Results Available

NCT05211232 | ACTIVE_NOT_RECRUITING | PHASE3

450 participants

Neoadjuvant and Adjuvant Tislelizumab for Nasopharyngeal Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-06-10

Completion:

2026-06-02

Conditions

• Nasopharyngeal Carcinoma

Interventions

• DRUG

No Results Yet

NCT05203445 | ACTIVE_NOT_RECRUITING | PHASE2

6 participants

A Study of Olaparib and Pembrolizumab in People With Triple Negative Breast Cancer (TNBC) or Hormone Receptor-positive HER2-negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-01-31

Completion:

2025-05-29

Conditions

• Breast Cancer

Interventions

• DRUG

Results Available

NCT05202951 | ACTIVE_NOT_RECRUITING

350 participants

Chronic Pain and Hemophilia

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2022-02-28

Completion:

2025-12-18

Conditions

• Chronic Pain
• Hemophilia

Interventions

• OTHER

No Results Yet

NCT05201833 | ACTIVE_NOT_RECRUITING

300 participants

TRACK-TBI Longitudinal Biomarker Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2022-03-01

Completion:

2026-06-30

Conditions

• Traumatic Brain Injury

Interventions

• BEHAVIORAL
• PROCEDURE

No Results Yet

NCT05200559 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

25 participants

T-regulatory Cell Depletion With E7777 Combined With Pembrolizumab in Recurrent or Metastatic Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-09-30

Completion:

2030-05-31

Conditions

• Epithelial Ovarian Cancer

Interventions

• DRUG

No Results Yet

NCT05189821 | RECRUITING

50 participants

RFA Treatment for Papillary Thyroid Microcarcinoma

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2021-11-01

Completion:

2027-11-30

Conditions

• Papillary Thyroid Microcarcinoma

Interventions

• PROCEDURE

No Results Yet

NCT05189808 | RECRUITING

50 participants

Radiofrequency Ablation for BIII Thyroid Nodules

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2020-08-01

Completion:

2027-08-31

Conditions

• Indeterminate Bethesda III Thyroid Nodules

Interventions

• PROCEDURE

No Results Yet

NCT05189314 | RECRUITING

100 participants

RFA of Benign Thyroid Nodules: Clinical Outcomes and Quality of Life Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2019-08-30

Completion:

2027-08-31

Conditions

• Thyroid Nodules

Interventions

• PROCEDURE
• DEVICE

No Results Yet

NCT05185947 | COMPLETED | PHASE2

21 participants

Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal Carcinomatosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-10-13

Completion:

2025-01-27

Conditions

• Gynecologic Cancer
• Gynecologic Neoplasms
• Peritoneal Carcinomatosis
• Peritoneal Neoplasms
• Ovarian Cancer
• Ovarian Neoplasms
• Colorectal Cancer
• Colorectal Neoplasms
• Appendiceal Cancer
• Appendiceal Neoplasms
• Cholangiocarcinoma
• Breast Cancer

Interventions

• DRUG
• DIAGNOSTIC_TEST
• PROCEDURE

Results Available

NCT05183178 | COMPLETED | PHASE4

17095 participants

Switching From Ticagrelor to Prasugrel in Patients With Acute Coronary Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-02-01

Completion:

2025-08-31

Conditions

• Acute Coronary Syndrome

Interventions

• DRUG

No Results Yet

NCT05174312 | COMPLETED | NA

100 participants

Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve Decongestion Management System (DMS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-07-11

Completion:

2025-01-10

Conditions

• Acute Decompensated Heart Failure

Interventions

• DEVICE
• DRUG

Results Available

NCT05156281 | ACTIVE_NOT_RECRUITING | PHASE3

1007 participants

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-12-13

Completion:

2026-07-23

Conditions

• Relapsing Multiple Sclerosis

Interventions

• DRUG

No Results Yet

NCT05155033 | RECRUITING | PHASE2

78 participants

Phase II Trial of Combination Anti-PD-1 and Aldesleukin for Metastatic Melanoma and Renal Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-08-18

Completion:

2031-09-01

Conditions

• Metastatic Melanoma
• Advanced Locoregional Melanoma
• Metastatic Renal Cell Carcinoma
• Clear Cell Histology

Interventions

• DRUG

No Results Yet

NCT05148000 | COMPLETED | PHASE3

25 participants

Assess Aesthetic Improvement With QM1114-DP in Subjects With Moderate to Severe Lateral Canthal Lines and Glabellar Lines

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2023-01-23

Completion:

2023-03-31

Conditions

• Glabellar Frown Lines
• Canthal Lines

Interventions

• BIOLOGICAL

Results Available

NCT05147220 | ACTIVE_NOT_RECRUITING | PHASE3

1000 participants

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-12-16

Completion:

2026-07-23

Conditions

• Relapsing Multiple Sclerosis

Interventions

• DRUG

No Results Yet

NCT05142696 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

24 participants

A Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed ES-SCLC Patients in Combination With Carboplatin, Etoposide and Atezolizumab

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-07-13

Completion:

2029-03-09

Conditions

• Extensive Stage Small Cell Lung Cancer

Interventions

• DRUG
• OTHER

No Results Yet

NCT05139017 | RECRUITING | PHASE2/PHASE3

290 participants

A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-01-14

Completion:

2027-09-24

Conditions

• DLBCL
• Diffuse Large B-Cell Lymphoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT05116137 | ENROLLING_BY_INVITATION | NA

24 participants

The Impact of Resistance ExerciSe on Muscle Mass in GlioblaSToma Survivors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-03-01

Completion:

2027-12-31

Conditions

• Glioblastoma Multiforme of Brain
• Brain Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT05099003 | RECRUITING | PHASE1/PHASE2

132 participants

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-05-31

Completion:

2027-06-30

Conditions

• Malignant Glioma

Interventions

• PROCEDURE
• RADIATION
• DRUG

No Results Yet

NCT05093959 | COMPLETED | PHASE2

86 participants

Metformin for Older Patients With Heart Failure With Preserved Ejection Fraction

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-01-04

Completion:

2025-12-18

Conditions

• Heart Failure With Preserved Ejection Fraction

Interventions

• DRUG

No Results Yet

NCT05090371 | ACTIVE_NOT_RECRUITING | PHASE4

136 participants

A Multicenter Study of Continued Current Therapy vs Transition to Ofatumumab After Neurofilament (NfL) Elevation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-03-02

Completion:

2027-04-13

Conditions

• Relapsing-Remitting Multiple Sclerosis

Interventions

• DRUG

No Results Yet

NCT05058651 | RECRUITING | PHASE2/PHASE3

189 participants

Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-06-28

Completion:

2028-10-01

Conditions

• Advanced Extrapulmonary Neuroendocrine Carcinoma
• Metastatic Extrapulmonary Neuroendocrine Carcinoma
• Recurrent Extrapulmonary Neuroendocrine Carcinoma
• Unresectable Extrapulmonary Neuroendocrine Carcinoma

Interventions

• BIOLOGICAL
• PROCEDURE
• DRUG
• OTHER

No Results Yet

NCT05052216 | RECRUITING

120 participants

Development of a Wearable Point of Care Monitoring Device for Pediatric Obstructive Sleep Apnea

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2022-08-25

Completion:

2028-01-31

Conditions

• Pediatric Obstructive Sleep Apnea

No Results Yet

NCT05051566 | COMPLETED | PHASE1

26 participants

A Multiple Dose Study of LY3502970 in Healthy Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-09-16

Completion:

2022-04-04

Conditions

• Healthy

Interventions

• DRUG

Results Available

NCT05040841 | ACTIVE_NOT_RECRUITING | NA

534 participants

Supporting Sustained HIV Treatment Adherence After Initiation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-03-09

Completion:

2026-05-28

Conditions

• HIV Infections
• Adherence, Medication

Interventions

• BEHAVIORAL

No Results Yet

NCT05031780 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

286 participants

A Study Evaluating the Efficacy and Safety of Mitapivat (AG-348) in Participants With Sickle Cell Disease (RISE UP)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-02-11

Completion:

2025-10-30

Conditions

• Sickle Cell Disease

Interventions

• DRUG
• OTHER

No Results Yet

NCT05016219 | RECRUITING | NA

120 participants

Phase 2 - Rhythmic Light Therapy for Alzheimer's Disease Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2023-08-22

Completion:

2027-03-31

Conditions

• Mild Cognitive Impairment

Interventions

• DEVICE

No Results Yet

NCT05003843 | ACTIVE_NOT_RECRUITING | NA

229 participants

BOLT: Study of the Indigo® Aspiration System When Used in Patients With Deep Vein Thrombosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-09-30

Completion:

2025-11-18

Conditions

• Deep Vein Thrombosis
• DVT

Interventions

• DEVICE

No Results Yet

NCT04991974 | COMPLETED | PHASE2/PHASE3

373 participants

Opioid Use Disorder Treatment Linkage at Strategic Touchpoints Using Buprenorphine

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-09-17

Completion:

2026-01-31

Conditions

• Opioid-use Disorder

Interventions

• BEHAVIORAL
• DRUG

No Results Yet

NCT04983030 | COMPLETED | PHASE1/PHASE2

28 participants

Safety, Immunogenicity, Efficacy of Ad26.Mos4.HIV, MVA-BN-HIV and PGT121, PGDM1400, and VRC07-523LS in HIV-1-Infected Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-04-01

Completion:

2026-02-23

Conditions

• HIV
• Acquired Immunodeficiency Syndrome
• Immunologic Deficiency Syndrome, Acquired
• Sexually Transmitted Diseases, Viral
• Retroviridae Infections

Interventions

• BIOLOGICAL

No Results Yet

NCT04977076 | RECRUITING | NA

1270 participants

Comparison Between Direct Oral Anticoagulation (DOAC) Interruption and DOAC Continuation in Patients Undergoing Elective Invasive Coronary Angiography or Percutaneous Coronary Intervention

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-09-01

Completion:

2027-12-31

Conditions

• Atrial Fibrillation
• Coronary Artery Disease
• Anticoagulants

Interventions

• OTHER

No Results Yet

NCT04976322 | ENROLLING_BY_INVITATION | PHASE3

760 participants

A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol in Study Participants With Systemic Lupus Erythematosus

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-07-27

Completion:

2030-08-07

Conditions

• Systemic Lupus Erythematosus

Interventions

• DRUG

No Results Yet

NCT04956640 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

540 participants

Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-07-19

Completion:

2027-04-30

Conditions

• Carcinoma, Non-Small-Cell Lung
• Colorectal Neoplasms
• Endometrial Neoplasms
• Ovarian Neoplasms
• Pancreatic Neoplasms
• Biliary Tract Neoplasms

Interventions

• DRUG

No Results Yet

NCT04946851 | ENROLLING_BY_INVITATION

1400 participants

Addictions Neuroclinical Assessment (ANA)

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2021-08-12

Completion:

2031-12-31

Conditions

• Normal Physiology
• Alcohol Use Disorder

No Results Yet

NCT04944979 | ACTIVE_NOT_RECRUITING | PHASE3

30 participants

Clinical Assessment of Pharmacokinetics, Efficacy, and Safety of 10% IVIg in Pediatric PID Patients (KIDCARES10)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-03-31

Completion:

2026-12-31

Conditions

• Primary Immunodeficiency Disease

Interventions

• BIOLOGICAL

No Results Yet

NCT04935697 | COMPLETED | NA

3 participants

Non-invasive Vagal Neurostimulation (nVNS) for Traumatic Brain Injury (TBI)-Induced Acute Respiratory Distress

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-08-04

Completion:

2025-03-01

Conditions

• Acute Respiratory Distress Syndrome
• Acute Lung Injury
• Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
• Traumatic Brain Injury

Interventions

• DEVICE
• OTHER

Results Available

NCT04934293 | RECRUITING | NA

47 participants

Virtual Reality for Children in Radiotherapy (REVER)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-08-02

Completion:

2027-02-28

Conditions

• Virtual Reality
• Proton Therapy
• Pediatric Cancer

Interventions

• PROCEDURE

No Results Yet