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Clinical Trials

NCT04456569 | ACTIVE_NOT_RECRUITING | NA
20 participants

Geniculate Artery Embolization for Osteoarthritis

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-29
Start Date:
2022-02-01
Completion:
2027-08-01
Conditions
  • Osteo Arthritis Knee
  • Arthritis
  • Osteoarthritis
  • Osteoarthritis, Knee
Interventions
  • DEVICE
No Results Yet
NCT04444921 | ACTIVE_NOT_RECRUITING | PHASE3
205 participants

EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-29
Start Date:
2020-11-17
Completion:
2027-03-31
Conditions
  • Anal Basaloid Carcinoma
  • Anal Canal Cloacogenic Carcinoma
  • Metastatic Anal Squamous Cell Carcinoma
  • Recurrent Anal Squamous Cell Carcinoma
  • Stage III Anal Cancer AJCC v8
  • Stage IV Anal Cancer AJCC v8
  • Unresectable Anal Squamous Cell Carcinoma
Interventions
  • DRUG
  • BIOLOGICAL
No Results Yet
NCT04431024 | RECRUITING
300 participants

Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome

Study Type:
OBSERVATIONAL
Last Updated:
2026-05-29
Start Date:
2021-03-30
Completion:
2038-06-30
Conditions
  • Familial Cancer
  • BRCA1-Associated Protein-1 (BAP1) Mutations
  • Tumor Predisposition Syndrome (TPDS)
  • Mesothelioma
No Results Yet
NCT04401449 | COMPLETED
202 participants

Cardiopulmonary Inflammation and Multi-System Imaging During the Clinical Course of COVID-19 Infection in Asymptomatic and Symptomatic Persons

Study Type:
OBSERVATIONAL
Last Updated:
2026-05-29
Start Date:
2020-05-21
Completion:
2023-08-31
Conditions
  • Acute and Long Term Effects of COVID-19 on Systemic Inflammation
  • Acute and Long Term Effects of COVID-19 on Lung Function
  • Acute and Long Term Effects of COVID-19 on Cardiac Function
  • Acute and Long Term Effects of COVID-19 on Kidney Function
  • Acute and Long Term Effects of COVID-19 on Brain Function
No Results Yet
NCT04387656 | ACTIVE_NOT_RECRUITING
1877 participants

NCI COVID-19 in Cancer Patients, NCCAPS Study

Study Type:
OBSERVATIONAL
Last Updated:
2026-05-29
Start Date:
2020-06-05
Completion:
2024-03-20
Conditions
  • COVID-19 Infection
  • Hematopoietic and Lymphatic System Neoplasm
  • Malignant Solid Neoplasm
  • Metastatic Malignant Solid Neoplasm
Interventions
  • PROCEDURE
  • OTHER
No Results Yet
NCT04310007 | ACTIVE_NOT_RECRUITING | PHASE2
117 participants

Testing the Addition of the Pill Chemotherapy, Cabozantinib, to the Standard Immune Therapy Nivolumab Compared to Standard Chemotherapy for Non-small Cell Lung Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-29
Start Date:
2020-07-13
Completion:
2026-12-31
Conditions
  • Metastatic Lung Non-Squamous Non-Small Cell Carcinoma
  • Recurrent Lung Non-Squamous Non-Small Cell Carcinoma
  • Stage IV Lung Cancer AJCC v8
Interventions
  • PROCEDURE
  • DRUG
  • BIOLOGICAL
No Results Yet
NCT04267848 | RECRUITING | PHASE3
1210 participants

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-29
Start Date:
2020-06-16
Completion:
2027-01-31
Conditions
  • Lung Non-Small Cell Carcinoma
  • Lung Non-Small Cell Squamous Carcinoma
  • Lung Non-Squamous Non-Small Cell Carcinoma
  • Stage II Lung Cancer AJCC v8
  • Stage IIIA Lung Cancer AJCC v8
  • Stage IIIB Lung Cancer AJCC v8
Interventions
  • PROCEDURE
  • DRUG
  • OTHER
  • BIOLOGICAL
No Results Yet
NCT04221438 | TERMINATED | PHASE2
3 participants

Testing Treatment With Encorafenib and Binimetinib Before Surgery for Melanoma With Lymph Node Involvement

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-29
Start Date:
2021-09-22
Completion:
2024-06-10
Conditions
  • Melanoma of Unknown Primary
  • Metastatic Malignant Neoplasm in Lymph Node
  • Pathologic Stage IIIB Cutaneous Melanoma AJCC v8
  • Pathologic Stage IIIC Cutaneous Melanoma AJCC v8
  • Pathologic Stage IIID Cutaneous Melanoma AJCC v8
  • Recurrent Cutaneous Melanoma
Interventions
  • DRUG
  • PROCEDURE
  • OTHER
Results Available
NCT04195633 | RECRUITING | PHASE2
60 participants

Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-29
Start Date:
2021-01-25
Completion:
2027-04-15
Conditions
  • Acute Leukemia
  • Acute Lymphoblastic Leukemia
  • Acute Myeloid Leukemia
  • Adult Diffuse Large Cell Lymphoma
  • Anaplastic Large Cell Lymphoma
  • Burkitt Lymphoma
  • Chronic Myeloid Leukemia, BCR-ABL1 Positive
  • Chronic Myelomonocytic Leukemia
  • Hodgkin Lymphoma
  • Lymphoblastic Lymphoma
  • Lymphoplasmacytic Lymphoma
  • Mantle Cell Lymphoma
  • Mixed Phenotype Acute Leukemia
  • Myelodysplastic Syndrome
  • Prolymphocytic Leukemia
  • Refractory Chronic Lymphocytic Leukemia
  • Refractory Follicular Lymphoma
  • Refractory Marginal Zone Lymphoma
  • Refractory Small Lymphocytic Lymphoma
Interventions
  • PROCEDURE
  • DRUG
  • BIOLOGICAL
  • RADIATION
No Results Yet
NCT04195555 | ACTIVE_NOT_RECRUITING | PHASE2
3 participants

Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-29
Start Date:
2020-07-20
Completion:
2025-03-31
Conditions
  • Recurrent Ependymoma
  • Recurrent Ewing Sarcoma
  • Recurrent Hepatoblastoma
  • Recurrent Langerhans Cell Histiocytosis
  • Recurrent Malignant Germ Cell Tumor
  • Recurrent Malignant Glioma
  • Recurrent Malignant Solid Neoplasm
  • Recurrent Medulloblastoma
  • Recurrent Neuroblastoma
  • Recurrent Non-Hodgkin Lymphoma
  • Recurrent Osteosarcoma
  • Recurrent Peripheral Primitive Neuroectodermal Tumor
  • Recurrent Rhabdoid Tumor
  • Recurrent Rhabdomyosarcoma
  • Recurrent Soft Tissue Sarcoma
  • Recurrent WHO Grade 2 Glioma
  • Refractory Ependymoma
  • Refractory Ewing Sarcoma
  • Refractory Hepatoblastoma
  • Refractory Langerhans Cell Histiocytosis
  • Refractory Malignant Germ Cell Tumor
  • Refractory Malignant Glioma
  • Refractory Malignant Solid Neoplasm
  • Refractory Medulloblastoma
  • Refractory Neuroblastoma
  • Refractory Non-Hodgkin Lymphoma
  • Refractory Osteosarcoma
  • Refractory Peripheral Primitive Neuroectodermal Tumor
  • Refractory Rhabdoid Tumor
  • Refractory Rhabdomyosarcoma
  • Refractory Soft Tissue Sarcoma
  • Refractory WHO Grade 2 Glioma
  • Wilms Tumor
Interventions
  • DRUG
Results Available
NCT04181060 | RECRUITING | PHASE3
300 participants

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-29
Start Date:
2020-12-28
Completion:
2026-12-31
Conditions
  • Advanced Lung Non-Squamous Non-Small Cell Carcinoma
  • Metastatic Lung Non-Squamous Non-Small Cell Carcinoma
  • Recurrent Lung Non-Squamous Non-Small Cell Carcinoma
  • Stage IIIB Lung Cancer AJCC v8
  • Stage IV Lung Cancer AJCC v8
Interventions
  • BIOLOGICAL
  • PROCEDURE
  • DRUG
No Results Yet
NCT04175912 | ACTIVE_NOT_RECRUITING | PHASE2
40 participants

Testing the Combination of Pevonedistat With Chemotherapy for Bile Duct Cancer of the Liver

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-29
Start Date:
2020-03-16
Completion:
2023-11-27
Conditions
  • Metastatic Cholangiocarcinoma
  • Metastatic Hepatocellular Carcinoma
  • Stage III Hepatocellular Carcinoma AJCC v8
  • Stage III Intrahepatic Cholangiocarcinoma AJCC v8
  • Stage IIIA Hepatocellular Carcinoma AJCC v8
  • Stage IIIA Intrahepatic Cholangiocarcinoma AJCC v8
  • Stage IIIB Hepatocellular Carcinoma AJCC v8
  • Stage IIIB Intrahepatic Cholangiocarcinoma AJCC v8
  • Stage IV Hepatocellular Carcinoma AJCC v8
  • Stage IV Intrahepatic Cholangiocarcinoma AJCC v8
  • Stage IVA Hepatocellular Carcinoma AJCC v8
  • Stage IVB Hepatocellular Carcinoma AJCC v8
  • Unresectable Cholangiocarcinoma
  • Unresectable Hepatocellular Carcinoma
  • Unresectable Intrahepatic Cholangiocarcinoma
Interventions
  • DRUG
Results Available
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