Clinical Trials

NCT06483789 | RECRUITING | PHASE2

240 participants

Efficacy and Safety of HB-1 for Panic Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2024-10-29
Completion:: 2027-01-31

Conditions

Panic Disorder
Mental Illness

Interventions

DRUG

No Results Yet

NCT06482827 | COMPLETED | NA

18 participants

Treatment for Diabetic Neuropathy Using Repetitive Transcranial Magnetic Stimulation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2025-01-01
Completion:: 2025-09-01

Conditions

Diabetic Neuropathies

Interventions

DEVICE

No Results Yet

NCT06479707 | ACTIVE_NOT_RECRUITING | NA

20 participants

Digital Literacy Intervention to Address Support, Literacy and Communication in Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2024-11-07
Completion:: 2026-03-30

Conditions

Quality of Life
Aging
Technology
Literacy

Interventions

BEHAVIORAL

No Results Yet

NCT06478186 | RECRUITING | PHASE4

120 participants

Knee Osteoarthritis Treatment With Zilretta vs. Kenalog in the Context of Type II Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2024-08-16
Completion:: 2026-12-16

Conditions

Osteoarthritis, Knee
Diabetes Mellitus, Type 2

Interventions

DRUG

No Results Yet

NCT06477419 | RECRUITING | PHASE2

33 participants

A Study of Sacituzumab Govitecan in People With Mesothelioma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2024-06-21
Completion:: 2029-06-21

Conditions

Mesothelioma
Mesotheliomas Pleural
Mesothelioma; Pleura

Interventions

DRUG

No Results Yet

NCT06469307 | RECRUITING | NA

40 participants

Driving Inclusivity, Validity, and Equity in Research Through Strategic Engagement (DIVERSE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2024-12-09
Completion:: 2026-07-01

Conditions

Blood Cancer
Leukemia

Interventions

OTHER

No Results Yet

NCT06468228 | ACTIVE_NOT_RECRUITING | PHASE3

1400 participants

A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2024-06-27
Completion:: 2026-12-31

Conditions

Hidradenitis Suppurativa

Interventions

DRUG

No Results Yet

NCT06465017 | TERMINATED | NA

149 participants

ImmunoPET Targeting Trophoblast Cell-Surface Antigen 2 (Trop-2) in Thyroid Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2024-06-13
Completion:: 2024-12-31

Conditions

Tumor
Solid Tumor
Thyroid Cancer
Positron-Emission Tomography

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06455475 | TERMINATED | NA

120 participants

Derm-Maxx in Patients With Diabetic Foot Ulcers Unresponsive to Standard of Care Treatment Alone

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2024-10-25
Completion:: 2026-04-01

Conditions

Diabetic Foot Ulcer

Interventions

OTHER

No Results Yet

NCT06455449 | RECRUITING | PHASE3

240 participants

A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2024-06-20
Completion:: 2027-05-14

Conditions

Polymyositis, Dermatomyositis

Interventions

COMBINATION_PRODUCT
OTHER

No Results Yet

NCT06447168 | RECRUITING

424 participants

A Study Observing Everyday Effectiveness and Safety of the Drug Elafibranor in Participants With Primary Biliary Cholangitis Who Are Receiving Ongoing Treatment

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-28
Start Date:: 2024-10-14
Completion:: 2032-07-15

Conditions

Primary Biliary Cholangitis

No Results Yet

NCT06431893 | ENROLLING_BY_INVITATION | PHASE3

100 participants

A Long-term Extension Study to Assess the Long-term Safety and Efficacy of Pegtibatinase Treatment in Participants ≥5 to ≤65 Years of Age With Classical Homocystinuria (HCU) (ENSEMBLE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2024-04-30
Completion:: 2030-08-31

Conditions

Homocystinuria

Interventions

DRUG

No Results Yet

NCT06431815 | ACTIVE_NOT_RECRUITING

228 participants

ADVENT Post Approval Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-28
Start Date:: 2024-09-25
Completion:: 2028-10-31

Conditions

Paroxysmal Atrial Fibrillation

Interventions

DEVICE

No Results Yet

NCT06412848 | ACTIVE_NOT_RECRUITING

360 participants

JAVEMACS: Japan AVElumab Maintenance And Continuous Treatment Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-28
Start Date:: 2024-05-09
Completion:: 2026-06-30

Conditions

Urothelial Carcinoma

Interventions

DRUG

No Results Yet

NCT06411821 | RECRUITING | PHASE2

38 participants

Ulixertinib in People With Histiocytic Neoplasms

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2024-05-07
Completion:: 2027-05-31

Conditions

Histiocytic Neoplasms

Interventions

DRUG

No Results Yet

NCT06400238 | ACTIVE_NOT_RECRUITING | PHASE2

35 participants

Testing Copanlisib as Potentially Targeting Treatment in Cancers With PTEN Expression (MATCH - Subprotocol Z1H)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2018-10-15
Completion:: 2023-01-27

Conditions

Advanced Lymphoma
Advanced Malignant Solid Neoplasm
Refractory Lymphoma
Refractory Malignant Solid Neoplasm
Refractory Multiple Myeloma

Interventions

PROCEDURE
DRUG

Results Available

NCT06395753 | ACTIVE_NOT_RECRUITING | PHASE2

55 participants

A Dose Finding Study of Debio 4228 in Participants With Advanced Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2024-05-23
Completion:: 2026-06-30

Conditions

Prostate Cancer

Interventions

DRUG

No Results Yet

NCT06390839 | ACTIVE_NOT_RECRUITING | PHASE2

43 participants

Testing Palbociclib (PD-0332991) as Potentially Targeting Treatment in Cancers With CDK4 or CDK6 Amplification (MATCH - Subprotocol Z1C)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2017-03-22
Completion:: 2022-01-15

Conditions

Advanced Lymphoma
Advanced Malignant Solid Neoplasm
Refractory Lymphoma
Refractory Malignant Solid Neoplasm

Interventions

PROCEDURE
DRUG

Results Available

NCT06390826 | ACTIVE_NOT_RECRUITING | PHASE2

10 participants

Testing Sunitinib as Potentially Targeted Treatment in Cancers With cKIT Genetic Changes (MATCH - Subprotocol V)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2016-11-01
Completion:: 2023-04-05

Conditions

Advanced Lymphoma
Advanced Malignant Solid Neoplasm
Refractory Lymphoma
Refractory Malignant Solid Neoplasm
Refractory Multiple Myeloma

Interventions

PROCEDURE
DRUG

Results Available

NCT06389565 | RECRUITING | NA

80 participants

Change My Story Task Shifted Mental Health Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2025-06-01
Completion:: 2026-06-30

Conditions

Hiv
Depression
Psychological Distress

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06385483 | ACTIVE_NOT_RECRUITING | PHASE2

19 participants

Testing Afatinib as Potentially Targeted Treatment in Cancers With EGFR Genetic Changes (MATCH - Subprotocol A)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2018-02-28
Completion:: 2022-12-06

Conditions

Advanced Lymphoma
Advanced Malignant Solid Neoplasm
Refractory Lymphoma
Refractory Malignant Solid Neoplasm
Refractory Multiple Myeloma

Interventions

DRUG
PROCEDURE

Results Available

NCT06385392 | COMPLETED

31 participants

Continuous Wearable Monitor for the Detection and Release of Freezing of Gait.

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-28
Start Date:: 2024-09-11
Completion:: 2025-04-28

Conditions

Parkinson Disease

Interventions

DEVICE

Results Available

NCT06383403 | ACTIVE_NOT_RECRUITING | PHASE3

69 participants

A Study of Elafibranor in Adults With Primary Biliary Cholangitis and Inadequate Response or Intolerance to Ursodeoxycholic Acid.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2024-07-09
Completion:: 2026-06-26

Conditions

Primary Biliary Cholangitis

Interventions

DRUG
OTHER

No Results Yet

NCT06378957 | RECRUITING | PHASE1

65 participants

Behavioral Pharmacology of Orally Administered THC and D-limonene

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2025-02-14
Completion:: 2027-07-01

Conditions

Subjective Drug Effects
THC
D-limonene

Interventions

DRUG

No Results Yet

NCT06376279 | ENROLLING_BY_INVITATION

1000 participants

Genetic Diagnosis in Inborn Errors of Metabolism

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-28
Start Date:: 2008-04-29
Completion:: 2030-12-31

Conditions

Metabolic Disease
Mitochondrial Diseases
Epilepsy in Children
Epilepsy
LHON
Motor Neuron Disease

Interventions

GENETIC

No Results Yet

NCT06370208 | ACTIVE_NOT_RECRUITING | NA

82 participants

Prophylactic Effect of Probiotic Streptococcus Salivarius eK12 Against Recurrent Streptococcus Pyogenes Pharyngotonsillitis Infection in Pediatrics

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2025-12-01
Completion:: 2026-07-30

Conditions

Streptococcus Pyogenes Pharyngotonsillitis

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06361888 | RECRUITING | PHASE2/PHASE3

502 participants

A Phase II/III Trial to Evaluate the Efficacy and Safety of Surufatinib Combined With Camrelizumab, Nab-paclitaxel, and Gemcitabine in Metastatic Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2024-05-08
Completion:: 2028-05-31

Conditions

Metastatic Pancreatic Cancer

Interventions

DRUG

No Results Yet

NCT06361706 | COMPLETED | NA

128 participants

VR-Enhanced Psychoeducation for Chronic Pain: A Primary Care Pilot Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2023-12-04
Completion:: 2025-12-18

Conditions

Chronic Pain
Central Sensitization

Interventions

BEHAVIORAL

No Results Yet

NCT06360588 | ACTIVE_NOT_RECRUITING | PHASE2

22 participants

Testing Copanlisib as Potentially Targeting Treatment in Cancers With PTEN Loss (MATCH - Subprotocol Z1G)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2018-10-08
Completion:: 2023-01-05

Conditions

Malignant Solid Neoplasm

Interventions

PROCEDURE
DRUG

Results Available

NCT06360575 | ACTIVE_NOT_RECRUITING | PHASE2

20 participants

Testing Crizotinib as Potentially Targeted Treatment in Cancers With MET Exon 14 Deletion Genetic Changes (MATCH - Subprotocol C2)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2016-07-20
Completion:: 2022-11-15

Conditions

Advanced Lymphoma
Advanced Malignant Solid Neoplasm
Refractory Lymphoma
Refractory Malignant Solid Neoplasm
Refractory Multiple Myeloma

Interventions

PROCEDURE
DRUG

Results Available

NCT06357988 | ACTIVE_NOT_RECRUITING | PHASE2

34 participants

Testing GDC-0449 (Vismodegib) as Potentially Targeted Treatment in Cancers With Smoothened or Patched 1 Mutant Tumors (MATCH - Subprotocol T)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2016-06-20
Completion:: 2022-11-04

Conditions

Advanced Lymphoma
Advanced Malignant Solid Neoplasm
Hematopoietic and Lymphatic System Neoplasm
Refractory Lymphoma
Refractory Malignant Solid Neoplasm
Refractory Multiple Myeloma

Interventions

PROCEDURE
DRUG

Results Available

NCT06353594 | RECRUITING | NA

1272 participants

Reduced Stent Strategy Versus Conventional Percutaneous Coronary Revascularization in Patients Presenting With STEMI

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2024-03-11
Completion:: 2026-09-30

Conditions

ST Elevation Myocardial Infarction

Interventions

DEVICE

No Results Yet

NCT06351371 | ACTIVE_NOT_RECRUITING | PHASE2

35 participants

Testing JNJ-42756493 (Erdafitinib) as Potentially Targeting Treatment in Cancers With FGFR Mutations or Fusions (MATCH - Subprotocol K2)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2018-07-03
Completion:: 2022-06-02

Conditions

Malignant Solid Neoplasm

Interventions

PROCEDURE
DRUG

Results Available

NCT06333951 | ACTIVE_NOT_RECRUITING | PHASE1

49 participants

Anvumetostat Alone or in Combination With Other Therapies in Subjects With Advanced Thoracic Tumors With Homozygous MTAP-deletion (Master Protocol) (MTAPESTRY 104).

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2024-09-17
Completion:: 2026-10-31

Conditions

Thoracic Tumors
Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT06331546 | RECRUITING | NA

80 participants

Gut Oxalate Absorption in Calcium Oxalate Stone Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2024-04-17
Completion:: 2030-12-31

Conditions

Kidney Stone
Kidney Calculi
Urolithiasis
Urolithiasis, Calcium Oxalate
Nephrolithiasis
Nephrolithiasis, Calcium Oxalate
Oxalate Urolithiasis
Oxaluria
Healthy

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT06330246 | RECRUITING | NA

40 participants

O. Formigenes Colonization in Calcium Oxalate Kidney Stone Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2024-04-17
Completion:: 2030-12-31

Conditions

Kidney Stone
Kidney Calculi
Urolithiasis
Urolithiasis, Calcium Oxalate
Nephrolithiasis
Nephrolithiasis, Calcium Oxalate
Oxalate Urolithiasis
Oxaluria

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06317662 | RECRUITING | PHASE2

153 participants

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2025-06-05
Completion:: 2028-12-31

Conditions

Acute Leukemia of Ambiguous Lineage
B Acute Lymphoblastic Leukemia

Interventions

DRUG
PROCEDURE
BIOLOGICAL

No Results Yet

NCT06308822 | ACTIVE_NOT_RECRUITING | PHASE2

35 participants

Testing JNJ-42756493 (Erdafitinib) as Potentially Targeting Treatment in Cancers With FGFR Amplifications (MATCH-Subprotocol K1)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2018-08-20
Completion:: 2022-07-27

Conditions

Advanced Lymphoma
Advanced Malignant Solid Neoplasm
Refractory Lymphoma
Refractory Malignant Solid Neoplasm
Refractory Multiple Myeloma

Interventions

PROCEDURE
DRUG

Results Available

NCT06303167 | ACTIVE_NOT_RECRUITING | PHASE2

19 participants

Testing AZD9291 as Potentially Targeted Treatment in Cancers With EGFR Genetic Changes (MATCH-Subprotocol E)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2016-01-08
Completion:: 2023-02-26

Conditions

Advanced Lymphoma
Advanced Malignant Solid Neoplasm
Hematopoietic and Lymphoid Cell Neoplasm
Refractory Lymphoma
Refractory Malignant Solid Neoplasm
Refractory Multiple Myeloma

Interventions

PROCEDURE
DRUG

Results Available

NCT06300411 | COMPLETED | PHASE1

25 participants

SRG-514 Administered Intraoperatively to Patients Undergoing Breast-conserving Cancer Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-28
Start Date:: 2024-07-29
Completion:: 2026-04-08

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet