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Clinical Trials

NCT02867592 | ACTIVE_NOT_RECRUITING | PHASE2
109 participants

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-27
Start Date:
2017-05-18
Completion:
2021-06-30
Conditions
  • Adrenal Cortical Carcinoma
  • Alveolar Soft Part Sarcoma
  • Central Nervous System Neoplasm
  • Childhood Clear Cell Sarcoma of Soft Tissue
  • Clear Cell Sarcoma of Soft Tissue
  • Ewing Sarcoma
  • Hepatoblastoma
  • Hepatocellular Carcinoma
  • Osteosarcoma
  • Recurrent Adrenal Cortical Carcinoma
  • Recurrent Alveolar Soft Part Sarcoma
  • Recurrent Clear Cell Sarcoma of Soft Tissue
  • Recurrent Ewing Sarcoma
  • Recurrent Hepatoblastoma
  • Recurrent Hepatocellular Carcinoma
  • Recurrent Kidney Wilms Tumor
  • Recurrent Malignant Solid Neoplasm
  • Recurrent Osteosarcoma
  • Recurrent Primary Malignant Central Nervous System Neoplasm
  • Recurrent Renal Cell Carcinoma
  • Recurrent Rhabdomyosarcoma
  • Recurrent Soft Tissue Sarcoma
  • Recurrent Thyroid Gland Medullary Carcinoma
  • Refractory Adrenal Cortical Carcinoma
  • Refractory Alveolar Soft Part Sarcoma
  • Refractory Clear Cell Sarcoma of Soft Tissue
  • Refractory Ewing Sarcoma
  • Refractory Hepatoblastoma
  • Refractory Hepatocellular Carcinoma
  • Refractory Malignant Solid Neoplasm
  • Refractory Osteosarcoma
  • Refractory Primary Central Nervous System Neoplasm
  • Refractory Primary Malignant Central Nervous System Neoplasm
  • Refractory Renal Cell Carcinoma
  • Refractory Rhabdomyosarcoma
  • Refractory Soft Tissue Sarcoma
  • Refractory Thyroid Gland Medullary Carcinoma
  • Refractory Wilms Tumor
  • Renal Cell Carcinoma
  • Rhabdomyosarcoma
  • Soft Tissue Sarcoma
  • Solid Neoplasm
  • Thyroid Gland Medullary Carcinoma
  • Wilms Tumor
Interventions
  • DRUG
  • OTHER
Results Available
NCT02568267 | ACTIVE_NOT_RECRUITING | PHASE2
534 participants

Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-27
Start Date:
2015-11-19
Completion:
2027-06-30
Conditions
  • Breast Cancer
  • Cholangiocarcinoma
  • Colorectal Cancer
  • Head and Neck Neoplasms
  • Lymphoma, Large-Cell, Anaplastic
  • Melanoma
  • Neuroendocrine Tumors
  • Non-Small Cell Lung Cancer
  • Ovarian Cancer
  • Pancreatic Cancer
  • Papillary Thyroid Cancer
  • Primary Brain Tumors
  • Renal Cell Carcinoma
  • Sarcomas
  • Salivary Gland Cancers
  • Adult Solid Tumor
Interventions
  • DRUG
No Results Yet
NCT02567435 | ACTIVE_NOT_RECRUITING | PHASE3
325 participants

Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-27
Start Date:
2016-06-01
Completion:
2023-06-30
Conditions
  • Alveolar Rhabdomyosarcoma
  • Botryoid-Type Embryonal Rhabdomyosarcoma
  • Embryonal Rhabdomyosarcoma
  • Rhabdomyosarcoma
  • Sclerosing Rhabdomyosarcoma
  • Spindle Cell Rhabdomyosarcoma
Interventions
  • DRUG
  • BIOLOGICAL
  • OTHER
  • RADIATION
Results Available
NCT02386800 | ACTIVE_NOT_RECRUITING | PHASE4
279 participants

CINC424A2X01B Rollover Protocol

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-27
Start Date:
2015-03-05
Completion:
2027-09-16
Conditions
  • Primary Myelofibrosis
  • Polycythemia Vera
  • Graft Versus Host Disease
  • Acute Myeloid Leukemia
  • Thalassemia
Interventions
  • DRUG
No Results Yet
NCT02166463 | ACTIVE_NOT_RECRUITING | PHASE3
600 participants

Brentuximab Vedotin and Combination Chemotherapy in Treating Children and Young Adults With Stage IIB, Stage IIIB, IVA, or IVB Hodgkin Lymphoma

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-27
Start Date:
2015-03-19
Completion:
2021-12-31
Conditions
  • Ann Arbor Stage IIB Hodgkin Lymphoma
  • Ann Arbor Stage IIIB Hodgkin Lymphoma
  • Ann Arbor Stage IVA Hodgkin Lymphoma
  • Ann Arbor Stage IVB Hodgkin Lymphoma
  • Childhood Hodgkin Lymphoma
  • Classic Hodgkin Lymphoma
Interventions
  • BIOLOGICAL
  • DRUG
  • OTHER
Results Available
NCT02112916 | ACTIVE_NOT_RECRUITING | PHASE3
847 participants

Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-27
Start Date:
2014-10-04
Completion:
2020-03-31
Conditions
  • Adult T Acute Lymphoblastic Leukemia
  • Ann Arbor Stage II Adult Lymphoblastic Lymphoma
  • Ann Arbor Stage II Childhood Lymphoblastic Lymphoma
  • Ann Arbor Stage III Adult Lymphoblastic Lymphoma
  • Ann Arbor Stage III Childhood Lymphoblastic Lymphoma
  • Ann Arbor Stage IV Adult Lymphoblastic Lymphoma
  • Ann Arbor Stage IV Childhood Lymphoblastic Lymphoma
  • Childhood T Acute Lymphoblastic Leukemia
Interventions
  • DRUG
  • RADIATION
Results Available
NCT01993810 | COMPLETED | PHASE3
330 participants

Comparing Photon Therapy To Proton Therapy To Treat Patients With Lung Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-27
Start Date:
2014-01-03
Completion:
2025-01-02
Conditions
  • Stage II Non-Small Cell Lung Cancer AJCC v7
  • Stage IIA Non-Small Cell Lung Carcinoma AJCC v7
  • Stage IIB Non-Small Cell Lung Carcinoma AJCC v7
  • Stage III Non-Small Cell Lung Cancer AJCC v7
  • Stage IIIA Non-Small Cell Lung Cancer AJCC v7
  • Stage IIIB Non-Small Cell Lung Cancer AJCC v7
Interventions
  • RADIATION
  • OTHER
  • DRUG
  • BIOLOGICAL
No Results Yet
NCT01689584 | RECRUITING | NA
11000 participants

COsegregation of VARiants in Panel of Genes

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-27
Start Date:
2012-07-02
Completion:
2037-07-02
Conditions
  • Gene Mutation-Related Cancer
  • Genetic Predisposition
Interventions
  • GENETIC
No Results Yet
NCT01351896 | ACTIVE_NOT_RECRUITING | PHASE2
49 participants

Lenalidomide and Vaccine Therapy in Treating Patients With Early-Stage Asymptomatic Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-27
Start Date:
2011-11-02
Completion:
2024-07-08
Conditions
  • Ann Arbor Stage I Small Lymphocytic Lymphoma
  • Ann Arbor Stage II Small Lymphocytic Lymphoma
  • Chronic Lymphocytic Leukemia
  • Chronic Lymphocytic Leukemia With Unmutated Immunoglobulin Heavy Chain Variable-Region Gene
  • Small Lymphocytic Lymphoma
  • Small Lymphocytic Lymphoma With Unmutated Immunoglobulin Heavy Chain Variable-Region Gene
  • Stage 0 Chronic Lymphocytic Leukemia
  • Stage I Chronic Lymphocytic Leukemia
  • Stage II Chronic Lymphocytic Leukemia
Interventions
  • PROCEDURE
  • DRUG
  • BIOLOGICAL
Results Available
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