Clinical Trials Updated in 2026

NCT06810505 | RECRUITING | PHASE3

420 participants

A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-02-13
Completion:: 2031-03-31

Conditions

Chronic Migraine

Interventions

DRUG

No Results Yet

NCT06806033 | RECRUITING | PHASE2

100 participants

A Study to Evaluate the Optimization of the Cytokine Release Syndrome Profile for Glofitamab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed/Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-03-05
Completion:: 2027-01-31

Conditions

B-Cell Non-Hodgkins Lymphoma

Interventions

DRUG

No Results Yet

NCT06804395 | RECRUITING

10000 participants

CanScan; Community-based Registry to Assess, Address and advaNce SCreening for cANcer Prevention and Management

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-26
Start Date:: 2024-10-01
Completion:: 2034-10-01

Conditions

Cancer Risk

No Results Yet

NCT06802224 | RECRUITING | PHASE4

18000 participants

The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-04-01
Completion:: 2028-07-31

Conditions

Anesthesia
Surgery With General Anesthesia
Noncardiac Surgery
Hypotension During Surgery
Acute Kidney Injury (AKI)
Myocardial Injury After Noncardiac Surgery (MINS)
Vasopressor

Interventions

DRUG

No Results Yet

NCT06799819 | RECRUITING | NA

284 participants

Impact of Free Mobility on FDG Uptake in PET Scans

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-04-30
Completion:: 2026-09-30

Conditions

Neoplasms
Whole Body Imaging

Interventions

BEHAVIORAL

No Results Yet

NCT06799156 | RECRUITING

205 participants

Clinical Study to Confirm the Safety and Performance of the Virtuoso Phaco-vitrectomy Device

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-12-03
Completion:: 2026-10-31

Conditions

Cataract
Vitrectomy
Vitrectomy Operation Under General Anesthesia

No Results Yet

NCT06788912 | RECRUITING | PHASE2

60 participants

Pembrolizumab (MK-3475) Plus Investigational Agents in Resectable Non-small Cell Lung Cancer (NSCLC) (MK-3475-01E/KEYMAKER-U01)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-03-20
Completion:: 2032-02-06

Conditions

Lung Neoplasm Malignant

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT06783309 | RECRUITING | PHASE1/PHASE2

72 participants

CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-05-12
Completion:: 2026-12-31

Conditions

Type 1 Diabetes Mellitus
T1D
T1DM
T1DM - Type 1 Diabetes Mellitus
Type 1 Diabetes in Adolescence
Type 1 Diabetes in Children
Type 1 Diabetes (Juvenile Onset)
Type 1 Diabetes
Type 1 Diabetes Patients
Type 1 Diabetes Mellitis

Interventions

DRUG

No Results Yet

NCT06780098 | RECRUITING | PHASE2

144 participants

Substudy 01I: A Study of Investigational Agents in Participants With Previously Treated Stage IV Squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01I/KEYMAKER-U01I)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-05-28
Completion:: 2032-03-02

Conditions

Lung Neoplasm

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06780085 | RECRUITING | PHASE2

96 participants

A Study of Investigational Agents in Participants With Previously Treated Stage IV Nonsquamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01H/KEYMAKER-U01)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-05-13
Completion:: 2032-03-12

Conditions

Carcinoma, Non-Small-Cell Lung

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06772623 | RECRUITING | PHASE1/PHASE2

252 participants

Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-03-06
Completion:: 2027-11-30

Conditions

Non Small Cell Lung Carcinoma

Interventions

DRUG

No Results Yet

NCT06772181 | ACTIVE_NOT_RECRUITING | NA

40 participants

A Digital Health Intervention to Improve Symptoms and Physical Activity During Breast Radiation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-03-04
Completion:: 2026-04-30

Conditions

Breast Carcinoma

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06771791 | RECRUITING | PHASE3

110 participants

Evaluation of the Efficacy of Oral Immunotherapy With Raw Apple in Patients Allergic to Birch Pollen and Apple: Prospective, Multicenter, Comparative Phase III Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-01-08
Completion:: 2027-05-05

Conditions

Allergies

Interventions

OTHER

No Results Yet

NCT06760507 | RECRUITING | NA

3209 participants

Evaluating an Evidence-Based Family History Screening Program Adapted to Increase Reach and Uptake of Screening for BRCA-Associated Cancers in Rural Public Health Clinics

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-02-01
Completion:: 2028-06-30

Conditions

Breast Cancer
Ovarian Cancer

Interventions

OTHER

No Results Yet

NCT06747429 | RECRUITING | NA

80 participants

High Fat Diet for Cardiac Metabolic Reprogramming

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2026-01-15
Completion:: 2026-06-30

Conditions

Non-ischemic Dilated Cardiomyopathy
Heart Failure With Reduced Ejection Fraction

Interventions

OTHER

No Results Yet

NCT06746337 | ACTIVE_NOT_RECRUITING | NA

100 participants

IMAGINE: Pilot Trial of a Digital Group Intervention to Prevent Perinatal Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-03-10
Completion:: 2026-10-31

Conditions

Depression During Pregnancy
Depression, Postpartum

Interventions

BEHAVIORAL

No Results Yet

NCT06745258 | NOT_YET_RECRUITING

7 participants

ICARE-LCS QUERI Partnered Evaluation Initiative: Integrating Comprehensive Tobacco Treatment to Enhance Lung Cancer Screening

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-26
Start Date:: 2026-10-01
Completion:: 2027-06-30

Conditions

Tobacco Dependence Treatment
Lung Cancer Screening

Interventions

OTHER

No Results Yet

NCT06744855 | ENROLLING_BY_INVITATION | NA

16 participants

Effect of Semiconductor Embedded Therapeutic Gloves for Hand Osteoarthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-01-01
Completion:: 2026-06-21

Conditions

Hand Osteoarthritis
Osteoarthritis

Interventions

DEVICE

No Results Yet

NCT06744595 | ENROLLING_BY_INVITATION | NA

40 participants

Personalized Education and Genetic Counseling to Increase Genetic Testing in Patients With a Known Family History of Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-02-12
Completion:: 2026-06-30

Conditions

Pancreatic Carcinoma

Interventions

PROCEDURE
OTHER
GENETIC

No Results Yet

NCT06744283 | RECRUITING

20 participants

Experience and Management of Cancer Screening-Related Anxiety in Fanconi Anemia

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-26
Start Date:: 2026-05-28
Completion:: 2026-07-01

Conditions

Fanconi Anemia

No Results Yet

NCT06741657 | COMPLETED | PHASE1

404 participants

A Study to Find Out How Litifilimab is Processed in the Body in Healthy Participants When Given Under the Skin in 3 Different Ways

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-01-02
Completion:: 2026-03-10

Conditions

Healthy Volunteer

Interventions

DRUG
DEVICE

No Results Yet

NCT06735885 | RECRUITING | NA

240 participants

fMRI Neurofeedback With Matter Neuroscience App

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-08-12
Completion:: 2027-06-15

Conditions

Depression Mild
Depression
Depression Moderate

Interventions

DEVICE
OTHER

No Results Yet

NCT06733935 | RECRUITING | PHASE1/PHASE2

240 participants

A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2024-11-04
Completion:: 2028-10-31

Conditions

Systemic Sclerosis
Idiopathic Inflammatory Myopathies
Antineutrophil Cytoplasmic Antibody-Associated Vasculitis
Rheumatoid Arthritis

Interventions

DRUG

No Results Yet

NCT06731907 | RECRUITING | PHASE2

90 participants

A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-03-30
Completion:: 2032-03-12

Conditions

Non-small Cell Lung Cancer

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06730126 | RECRUITING | PHASE2

15 participants

Study of the ITK Inhibitor Soquelitinib to Reduce Lymphoproliferation and Improve Cytopenias in Autoimmune Lymphoproliferative Syndrome (ALPS)-FAS Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-03-10
Completion:: 2026-12-01

Conditions

Autoimmune Lymphoproliferative Syndrome

Interventions

DRUG

No Results Yet

NCT06710938 | RECRUITING | NA

11 participants

Thoracoabdominal Artery Stent Graft System Exploratory Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-07-24
Completion:: 2028-06-30

Conditions

Thoracoabdominal Aortic Aneurysms

Interventions

DEVICE

No Results Yet

NCT06707207 | RECRUITING

40 participants

Predicting Future Errors During Skill Performance

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-26
Start Date:: 2026-05-28
Completion:: 2029-04-01

Conditions

Healthy

No Results Yet

NCT06704763 | COMPLETED | PHASE1

27 participants

A Drug-Drug Interaction Study of Orforglipron (LY3502970) With Quinidine in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2024-12-06
Completion:: 2025-02-05

Conditions

Healthy

Interventions

DRUG

Results Available

NCT06703125 | RECRUITING | NA

850 participants

The Alama Project: Autism Outcomes and Neurobehavioral Markers in Young Children Born to Mothers With HIV in Kenya

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-02-11
Completion:: 2029-02-28

Conditions

Autism

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06700122 | COMPLETED | NA

24 participants

Clinical Comparative Evaluation of the Use of Photodynamic Therapy in Conjunction With the Use of Vitamin D in Management Stage II Grade B Periodontitis Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-03-01
Completion:: 2025-05-01

Conditions

Vitamin D Deficiency

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06698549 | COMPLETED | PHASE1

12 participants

A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of ALG-097558 in Subjects With Renal Impairment and in Healthy Subjects With Normal Renal Function

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-02-20
Completion:: 2025-07-23

Conditions

COVID 19

Interventions

DRUG

No Results Yet

NCT06694454 | RECRUITING | PHASE1/PHASE2

60 participants

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2026-05-28
Completion:: 2031-12-31

Conditions

Non-small Cell Lung Cancer (NSCLC)
Carcinoma, Non-Small Cell Lung
Non-Small Cell Lung Carcinoma
Non Small Cell Lung Cancer
Non Small Cell Lung Carcinoma

Interventions

DRUG

No Results Yet

NCT06690294 | NOT_YET_RECRUITING

110 participants

Assessing the Impact of Perceptions of Unpredictability on Objective Measures of Food Consumption and Metabolism

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-26
Start Date:: 2026-05-28
Completion:: 2027-01-30

Conditions

Healthy Volunteer
Obestity

No Results Yet

NCT06689930 | RECRUITING | NA

46 participants

Community-based Implementation of Adapted STAC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-05-22
Completion:: 2026-09-30

Conditions

Blood Pressure
Hypertension
Pregnancy Related
Health Equity

Interventions

OTHER

No Results Yet

NCT06684522 | RECRUITING | EARLY_PHASE1

10 participants

Upadacitinib as a Novel Treatment for Refractory Eyelid Dermatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-12-18
Completion:: 2027-06-30

Conditions

Eyelid Dermatitis

Interventions

DRUG

No Results Yet

NCT06682988 | RECRUITING | PHASE2

110 participants

A Study to Assess Adverse Events and Change in Disease Activity in Participants With Platinum-Resistant Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha Expression Treated With Intravenously (IV) Infused Mirvetuximab Soravtansine

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-05-28
Completion:: 2026-07-31

Conditions

Advanced High-Grade Epithelial Ovarian Cancer
Primary Peritoneal Cancer
Fallopian Tube Cancers

Interventions

DRUG

No Results Yet

NCT06676059 | RECRUITING

10000 participants

SMART-r: Substance Monitoring and Active Relapse Tracking Repository

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-26
Start Date:: 2026-05-28
Completion:: 2044-12-31

Conditions

Alcoholism
Substance-Related Disorders

No Results Yet

NCT06673303 | COMPLETED | NA

47 participants

Investigating The Role of Noise Correlations in Learning

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2024-12-14
Completion:: 2025-09-01

Conditions

Noise Correlations
Learning Quality

Interventions

BEHAVIORAL
DIAGNOSTIC_TEST

No Results Yet

NCT06672146 | RECRUITING | PHASE2

93 participants

Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2025-05-16
Completion:: 2027-03-31

Conditions

Acute Myeloid Leukemia

Interventions

PROCEDURE
DRUG

No Results Yet

NCT06667700 | RECRUITING | PHASE3

3082 participants

A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-26
Start Date:: 2024-12-02
Completion:: 2031-01-26

Conditions

Coronavirus Disease (COVID-19)

Interventions

DRUG

No Results Yet