Clinical Trials

NCT06353386 | RECRUITING | PHASE1/PHASE2

220 participants

Substudy 01A: Safety and Efficacy of Opevesostat (MK-5684)-Based Treatment Combinations or Opevesostat Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-01A)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-05-20

Completion:

2029-01-15

Conditions

• Prostatic Neoplasms, Castration-Resistant

Interventions

• DRUG

No Results Yet

NCT06352229 | RECRUITING | NA

2327 participants

The Playful Learning in Infancy Program

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-06-01

Completion:

2026-11-30

Conditions

• Parent-Child Relations
• Infant Development

Interventions

• BEHAVIORAL

No Results Yet

NCT06337552 | ACTIVE_NOT_RECRUITING | NA

39 participants

High-Fermented Food Intervention Among Locally Advanced Rectal Cancer Patients (The FEED Trial)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-04-04

Completion:

2027-03-31

Conditions

• Rectal Cancer
• Non-Small Cell Lung Cancer

Interventions

• OTHER

No Results Yet

NCT06329141 | COMPLETED | PHASE2

99 participants

A Study to Assess the Efficacy and Safety of Vutiglabridin in Early Parkinson's Disease Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-07-22

Completion:

2025-12-16

Conditions

• Parkinson Disease

Interventions

• DRUG

No Results Yet

NCT06328712 | RECRUITING | PHASE1/PHASE2

27 participants

Evaluate the Safety and Efficacy of EN001 in Patients With Charcot-Marie-Tooth Disease Type 1A(CMT1A) (Phase 1b: Open-label, Dose-escalation, Single-center; Phase 2a: Randomized, Double-blind, Placebo-controlled, Multicenter)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-05-30

Completion:

2026-12-31

Conditions

• Charcot-Marie-Tooth Disease Type 1A

Interventions

• DRUG

No Results Yet

NCT06327100 | RECRUITING | PHASE1/PHASE2

33 participants

Open Label Phase 1/2 Study of Tasquinimod in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (Post-PV MF), or Post-Essential Thrombocytosis Myelofibrosis (Post-ET MF)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-08-01

Completion:

2029-05-01

Conditions

• Primary Myelofibrosis
• Post-polycythemia Vera Myelofibrosis
• Post-Essential Thrombocytosis Myelofibrosis

Interventions

• DRUG

No Results Yet

NCT06325683 | SUSPENDED | PHASE2

184 participants

Anti-Lag-3 (Relatlimab) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-11-08

Completion:

2028-07-15

Conditions

• Progressive Glioblastoma
• Recurrent Glioblastoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet

NCT06324357 | RECRUITING | PHASE1/PHASE2

768 participants

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-06-03

Completion:

2029-01-08

Conditions

• Metastatic Breast Cancer
• Metastatic Gastric Adenocarcinoma
• Gastroesophageal Junction Adenocarcinoma
• Esophageal Adenocarcinoma
• Colorectal Cancer

Interventions

• DRUG

No Results Yet

NCT06314282 | RECRUITING

200 participants

INTERSTELLAR - International Study Evaluating Lupus Outcomes After Anifrolumab Real World Use

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2024-10-22

Completion:

2027-12-31

Conditions

• Systemic Lupus Erythematosus (SLE)

No Results Yet

NCT06308913 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

10 participants

Pembrolizumab, INCB081776, and Radiation Therapy for Head and Neck Squamous Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-09-18

Completion:

2026-10-31

Conditions

• Head and Neck Squamous Cell Carcinoma

Interventions

• DRUG
• RADIATION

No Results Yet

NCT06307535 | RECRUITING | NA

200 participants

A Study of Meaning-Centered Psychotherapy for Caregivers to People With Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-03-13

Completion:

2029-03-01

Conditions

• Caregiver Burden
• Caregiver Burnout
• Caregiver Stress Syndrome

Interventions

• BEHAVIORAL

No Results Yet

NCT06304753 | COMPLETED | NA

66 participants

ContriBution of Digital RemOte MoniToring to IMPROVing The Effectiveness of Treatment in Patients With Chronic Heart Failure With Low Ejection Fraction

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-10-27

Completion:

2025-06-01

Conditions

• Chronic Heart Failure With Low Ejection Fraction

Interventions

• DEVICE

No Results Yet

NCT06300892 | RECRUITING

300 participants

Surgical Site Infections and the Microbiome: Understanding the Pathogenesis of Surgical Site Infections

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2024-04-01

Completion:

2026-06-15

Conditions

• Open GI Surgery

Interventions

• OTHER

No Results Yet

NCT06300294 | COMPLETED | NA

68 participants

Acute Coronary Syndrome and Acupressure

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-05-05

Completion:

2025-04-01

Conditions

• Acute Coronary Syndrome
• Nursing

Interventions

• OTHER

No Results Yet

NCT06299514 | RECRUITING | NA

600 participants

RAFT - Pace &Ablate

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-04-25

Completion:

2028-12-31

Conditions

• Atrial Fibrillation
• Heart Failure
• Pacemaker
• Arrhythmia Atrial

Interventions

• DEVICE
• DRUG

No Results Yet

NCT06299410 | RECRUITING | PHASE1

42 participants

PET Study to Evaluate Brain Receptor Occupancy, Safety and Pharmacokinetics of ITI-1284 in Healthy Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-04-11

Completion:

2026-07-31

Conditions

• Healthy Volunteers

Interventions

• DRUG

No Results Yet

NCT06290128 | RECRUITING | PHASE3

140 participants

A Study to Test the Effects and Safety of Riliprubart in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) for Which the Usual Treatments do Not Work

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-07-12

Completion:

2027-05-17

Conditions

• Chronic Inflammatory Demyelinating Polyradiculoneuropathy
• Polyneuropathy, Inflammatory Demyelinating, Chronic

Interventions

• DRUG

No Results Yet

NCT06279143 | COMPLETED

210 participants

The Diagnostic Accuracy of Advanced Imaging in Identifying Suspected Skin Cancer (Basal Cell Carcinoma) Around the Eyes

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2024-04-04

Completion:

2026-03-11

Conditions

• BCC - Basal Cell Carcinoma
• BCC
• Skin Diseases
• Eyelid Tumor
• Eyelid Diseases

No Results Yet

NCT06275490 | COMPLETED | NA

20 participants

Post Extraction Changes Following Ridge Preservation Using Partially Demineralized Dentin Block Versus L- PRF Block

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-01-01

Completion:

2025-11-22

Conditions

• Socket Preservation

Interventions

• BIOLOGICAL

No Results Yet

NCT06274879 | RECRUITING | PHASE2

36 participants

Safety of Biliary Intraductal Radiofrequency Ablation in Patients With Unresectable Extrahepatic Biliary Tract Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2026-05-20

Completion:

2029-12-30

Conditions

• Bile Duct Cancer

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT06269783 | COMPLETED | NA

172 participants

Dual-process Mechanisms of Action for sipIT Intervention Effects in Patients With Urolithiasis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-01-10

Completion:

2025-02-12

Conditions

• Kidney Stone
• Urolithiasis
• Nephrolithiasis

Interventions

• BEHAVIORAL

No Results Yet

NCT06256588 | RECRUITING | PHASE3

864 participants

A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-03-21

Completion:

2028-06-30

Conditions

• Neoplasms, Head and Neck

Interventions

• DRUG

No Results Yet

NCT06253884 | NOT_YET_RECRUITING | NA

30 participants

Utilizing Carbon Dioxide for Assessing Coronary Blood Flow in Subjects With Coronary Artery Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2027-01-10

Completion:

2027-11-15

Conditions

• Coronary Artery Disease

Interventions

• DEVICE

No Results Yet

NCT06249126 | RECRUITING | NA

218 participants

Primary Subtalar Arthrodesis for Calcaneal Fractures

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-09-02

Completion:

2026-12-31

Conditions

• Calcaneus Fracture

Interventions

• PROCEDURE

No Results Yet

NCT06234813 | COMPLETED | NA

20 participants

Targeting TFPI With Concizumab to Improve Haemostasis in Glanzmann Thrombasthenia Patients: an in Vitro Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-04-06

Completion:

2023-07-17

Conditions

• Glanzmann Thrombasthenia

Interventions

• OTHER

No Results Yet

NCT06219707 | COMPLETED | NA

60 participants

Electro-acupuncture for Irritable Bowel Syndrome With Constipation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-09-12

Completion:

2026-05-21

Conditions

• Irritable Bowel Syndrome With Constipation

Interventions

• DEVICE

No Results Yet

NCT06203912 | ACTIVE_NOT_RECRUITING | PHASE1

3 participants

Donor Immune Cells (TGFbi NK Cells) and Isatuximab for the Treatment of Relapsed or Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-03-05

Completion:

2026-05-19

Conditions

• Recurrent Multiple Myeloma
• Refractory Multiple Myeloma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL
• OTHER

No Results Yet

NCT06203600 | RECRUITING | PHASE2/PHASE3

224 participants

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-06-24

Completion:

2027-10-31

Conditions

• Advanced Esophageal Adenocarcinoma
• Advanced Gastric Adenocarcinoma
• Advanced Gastroesophageal Junction Adenocarcinoma
• Clinical Stage II Esophageal Adenocarcinoma AJCC v8
• Clinical Stage III Esophageal Adenocarcinoma AJCC v8
• Clinical Stage III Gastric Cancer AJCC v8
• Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage IV Esophageal Adenocarcinoma AJCC v8
• Clinical Stage IV Gastric Cancer AJCC v8
• Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
• Metastatic Esophageal Adenocarcinoma
• Metastatic Gastric Adenocarcinoma
• Metastatic Gastroesophageal Junction Adenocarcinoma
• Unresectable Esophageal Adenocarcinoma
• Unresectable Gastric Adenocarcinoma
• Unresectable Gastroesophageal Junction Adenocarcinoma

Interventions

• PROCEDURE
• BIOLOGICAL
• DRUG
• OTHER

No Results Yet

NCT06199726 | ACTIVE_NOT_RECRUITING

16 participants

REFLECT: Reproductive Education and Fertility Links for Cancer Treatment

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2023-12-11

Completion:

2025-12-05

Conditions

• Reproductive Behavior

Interventions

• BEHAVIORAL

No Results Yet

NCT06188702 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

60 participants

S095035 as a Single Agent and in Combination in Adult Participants With Advanced or Metastatic Solid Tumors With Deletion of MTAP

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-04-29

Completion:

2027-05-01

Conditions

• MTAP-deleted Solid Tumors

Interventions

• DRUG

No Results Yet

NCT06185491 | ACTIVE_NOT_RECRUITING | NA

750 participants

Assessment of HGI (Hemoglobin Glycation Index) Variability Over Time in Patients Living With Diabetes Using Continuous Glucose Monitoring ( GAP OUEST )

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-06-24

Completion:

2028-09-30

Conditions

• Diabetes Mellitus

Interventions

• OTHER

No Results Yet

NCT06171685 | RECRUITING | PHASE2

300 participants

MMRC Horizon One: RRMM (MMRC-099)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-11-17

Completion:

2029-07-31

Conditions

• Relapse Multiple Myeloma
• Refractory Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT06156865 | RECRUITING | NA

45 participants

Using Neuroimaging and Behavioral Assessments to Understand Late Talking

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-01-19

Completion:

2027-06-30

Conditions

• Developmental Language Disorder
• Language Delay
• Language Development

Interventions

• BEHAVIORAL

No Results Yet

NCT06155747 | RECRUITING

100 participants

Transmission and Acquisition of Nontuberculous Mycobacteria Outbreak Investigation (TrANsMIt)

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2023-03-01

Completion:

2036-12-28

Conditions

• Nontuberculous Mycobacterial Pulmonary Infection
• Outbreak Investigation
• Healthcare Associated Infection
• Mycobacterium Infections

Interventions

• OTHER

No Results Yet

NCT06154447 | ACTIVE_NOT_RECRUITING | PHASE1

165 participants

Evaluation of VX-828 in Healthy Participants and in Participants With Cystic Fibrosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-12-12

Completion:

2026-07-16

Conditions

• Cystic Fibrosis

Interventions

• DRUG

No Results Yet

NCT06152627 | RECRUITING | NA

600 participants

Voice Therapy Per the Rehabilitation Treatment Specification System

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2026-02-03

Completion:

2027-06-29

Conditions

• Muscle Tension Dysphonia

Interventions

• BEHAVIORAL

No Results Yet

NCT06149897 | COMPLETED | NA

54 participants

Feasibility and Effectiveness of tDCS in the Treatment of Post-stroke Fatigue (EFECTS).

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-11-10

Completion:

2026-05-05

Conditions

• Stroke

Interventions

• DEVICE

No Results Yet

NCT06147037 | RECRUITING | PHASE1

70 participants

A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-07-31

Completion:

2028-05-12

Conditions

• Advanced Solid Tumor
• Metastatic Colorectal Carcinoma
• Head and Neck Squamous Cell Carcinoma
• Non-small Cell Lung Cancer
• Pancreatic Ductal Adenocarcinoma
• Gastric Cancer
• Renal Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT06121232 | ACTIVE_NOT_RECRUITING | NA

24 participants

Exploring the Benefit of Neuromodulation in Treating Chemo-induced Peripheral Neuropathy Using Peripheral Neuropathy Markers (Meissner's Corpuscles and Epidermal Nerve Fiber Density) and Sensory Testing (Quantitative Sensory and Gait Testing): A Single Center Feasibility Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-11-02

Completion:

2026-06-01

Conditions

• Neuropathy;Peripheral

Interventions

• DEVICE
• OTHER

No Results Yet

NCT06118554 | RECRUITING | NA

200 participants

3D Printing to Improve Nasal Irrigation Outcome

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2021-11-01

Completion:

2027-06-26

Conditions

• Chronic Rhinosinusitis With Nasal Polyps
• Chronic Rhinosinusitis Without Nasal Polyps

Interventions

• OTHER

No Results Yet