Clinical Trials

NCT06299514 | RECRUITING | NA

600 participants

RAFT - Pace &Ablate

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-04-25

Completion:

2028-12-31

Conditions

• Atrial Fibrillation
• Heart Failure
• Pacemaker
• Arrhythmia Atrial

Interventions

• DEVICE
• DRUG

No Results Yet

NCT06299410 | RECRUITING | PHASE1

42 participants

PET Study to Evaluate Brain Receptor Occupancy, Safety and Pharmacokinetics of ITI-1284 in Healthy Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-04-11

Completion:

2026-07-31

Conditions

• Healthy Volunteers

Interventions

• DRUG

No Results Yet

NCT06290141 | RECRUITING | PHASE3

160 participants

A Study to Test the Efficacy and Safety of Riliprubart Against the Usual Treatment of Intravenous Immunoglobulin (IVIg) in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-08-21

Completion:

2027-07-09

Conditions

• Chronic Inflammatory Demyelinating Polyneuropathy

Interventions

• DRUG

No Results Yet

NCT06290128 | RECRUITING | PHASE3

140 participants

A Study to Test the Effects and Safety of Riliprubart in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) for Which the Usual Treatments do Not Work

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-07-12

Completion:

2027-05-17

Conditions

• Chronic Inflammatory Demyelinating Polyradiculoneuropathy
• Polyneuropathy, Inflammatory Demyelinating, Chronic

Interventions

• DRUG

No Results Yet

NCT06279143 | COMPLETED

210 participants

The Diagnostic Accuracy of Advanced Imaging in Identifying Suspected Skin Cancer (Basal Cell Carcinoma) Around the Eyes

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2024-04-04

Completion:

2026-03-11

Conditions

• BCC - Basal Cell Carcinoma
• BCC
• Skin Diseases
• Eyelid Tumor
• Eyelid Diseases

No Results Yet

NCT06275490 | COMPLETED | NA

20 participants

Post Extraction Changes Following Ridge Preservation Using Partially Demineralized Dentin Block Versus L- PRF Block

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-01-01

Completion:

2025-11-22

Conditions

• Socket Preservation

Interventions

• BIOLOGICAL

No Results Yet

NCT06274879 | RECRUITING | PHASE2

36 participants

Safety of Biliary Intraductal Radiofrequency Ablation in Patients With Unresectable Extrahepatic Biliary Tract Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2026-05-20

Completion:

2029-12-30

Conditions

• Bile Duct Cancer

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT06269783 | COMPLETED | NA

172 participants

Dual-process Mechanisms of Action for sipIT Intervention Effects in Patients With Urolithiasis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-01-10

Completion:

2025-02-12

Conditions

• Kidney Stone
• Urolithiasis
• Nephrolithiasis

Interventions

• BEHAVIORAL

No Results Yet

NCT06256588 | RECRUITING | PHASE3

864 participants

A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-03-21

Completion:

2028-06-30

Conditions

• Neoplasms, Head and Neck

Interventions

• DRUG

No Results Yet

NCT06253884 | NOT_YET_RECRUITING | NA

30 participants

Utilizing Carbon Dioxide for Assessing Coronary Blood Flow in Subjects With Coronary Artery Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2027-01-10

Completion:

2027-11-15

Conditions

• Coronary Artery Disease

Interventions

• DEVICE

No Results Yet

NCT06249126 | RECRUITING | NA

218 participants

Primary Subtalar Arthrodesis for Calcaneal Fractures

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-09-02

Completion:

2026-12-31

Conditions

• Calcaneus Fracture

Interventions

• PROCEDURE

No Results Yet

NCT06234813 | COMPLETED | NA

20 participants

Targeting TFPI With Concizumab to Improve Haemostasis in Glanzmann Thrombasthenia Patients: an in Vitro Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-04-06

Completion:

2023-07-17

Conditions

• Glanzmann Thrombasthenia

Interventions

• OTHER

No Results Yet

NCT06219707 | COMPLETED | NA

60 participants

Electro-acupuncture for Irritable Bowel Syndrome With Constipation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-09-12

Completion:

2026-05-21

Conditions

• Irritable Bowel Syndrome With Constipation

Interventions

• DEVICE

No Results Yet

NCT06203912 | ACTIVE_NOT_RECRUITING | PHASE1

3 participants

Donor Immune Cells (TGFbi NK Cells) and Isatuximab for the Treatment of Relapsed or Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-03-05

Completion:

2026-05-19

Conditions

• Recurrent Multiple Myeloma
• Refractory Multiple Myeloma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL
• OTHER

No Results Yet

NCT06203600 | RECRUITING | PHASE2/PHASE3

224 participants

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-06-24

Completion:

2027-10-31

Conditions

• Advanced Esophageal Adenocarcinoma
• Advanced Gastric Adenocarcinoma
• Advanced Gastroesophageal Junction Adenocarcinoma
• Clinical Stage II Esophageal Adenocarcinoma AJCC v8
• Clinical Stage III Esophageal Adenocarcinoma AJCC v8
• Clinical Stage III Gastric Cancer AJCC v8
• Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage IV Esophageal Adenocarcinoma AJCC v8
• Clinical Stage IV Gastric Cancer AJCC v8
• Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
• Metastatic Esophageal Adenocarcinoma
• Metastatic Gastric Adenocarcinoma
• Metastatic Gastroesophageal Junction Adenocarcinoma
• Unresectable Esophageal Adenocarcinoma
• Unresectable Gastric Adenocarcinoma
• Unresectable Gastroesophageal Junction Adenocarcinoma

Interventions

• PROCEDURE
• BIOLOGICAL
• DRUG
• OTHER

No Results Yet

NCT06199726 | ACTIVE_NOT_RECRUITING

16 participants

REFLECT: Reproductive Education and Fertility Links for Cancer Treatment

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2023-12-11

Completion:

2025-12-05

Conditions

• Reproductive Behavior

Interventions

• BEHAVIORAL

No Results Yet

NCT06188702 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

60 participants

S095035 as a Single Agent and in Combination in Adult Participants With Advanced or Metastatic Solid Tumors With Deletion of MTAP

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-04-29

Completion:

2027-05-01

Conditions

• MTAP-deleted Solid Tumors

Interventions

• DRUG

No Results Yet

NCT06185491 | ACTIVE_NOT_RECRUITING | NA

750 participants

Assessment of HGI (Hemoglobin Glycation Index) Variability Over Time in Patients Living With Diabetes Using Continuous Glucose Monitoring ( GAP OUEST )

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-06-24

Completion:

2028-09-30

Conditions

• Diabetes Mellitus

Interventions

• OTHER

No Results Yet

NCT06171685 | RECRUITING | PHASE2

300 participants

MMRC Horizon One: RRMM (MMRC-099)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-11-17

Completion:

2029-07-31

Conditions

• Relapse Multiple Myeloma
• Refractory Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT06156865 | RECRUITING | NA

45 participants

Using Neuroimaging and Behavioral Assessments to Understand Late Talking

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-01-19

Completion:

2027-06-30

Conditions

• Developmental Language Disorder
• Language Delay
• Language Development

Interventions

• BEHAVIORAL

No Results Yet

NCT06155747 | RECRUITING

100 participants

Transmission and Acquisition of Nontuberculous Mycobacteria Outbreak Investigation (TrANsMIt)

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2023-03-01

Completion:

2036-12-28

Conditions

• Nontuberculous Mycobacterial Pulmonary Infection
• Outbreak Investigation
• Healthcare Associated Infection
• Mycobacterium Infections

Interventions

• OTHER

No Results Yet

NCT06154447 | ACTIVE_NOT_RECRUITING | PHASE1

165 participants

Evaluation of VX-828 in Healthy Participants and in Participants With Cystic Fibrosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-12-12

Completion:

2026-07-16

Conditions

• Cystic Fibrosis

Interventions

• DRUG

No Results Yet

NCT06152627 | RECRUITING | NA

600 participants

Voice Therapy Per the Rehabilitation Treatment Specification System

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2026-02-03

Completion:

2027-06-29

Conditions

• Muscle Tension Dysphonia

Interventions

• BEHAVIORAL

No Results Yet

NCT06149897 | COMPLETED | NA

54 participants

Feasibility and Effectiveness of tDCS in the Treatment of Post-stroke Fatigue (EFECTS).

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-11-10

Completion:

2026-05-05

Conditions

• Stroke

Interventions

• DEVICE

No Results Yet

NCT06147037 | RECRUITING | PHASE1

70 participants

A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-07-31

Completion:

2028-05-12

Conditions

• Advanced Solid Tumor
• Metastatic Colorectal Carcinoma
• Head and Neck Squamous Cell Carcinoma
• Non-small Cell Lung Cancer
• Pancreatic Ductal Adenocarcinoma
• Gastric Cancer
• Renal Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT06136559 | RECRUITING | PHASE3

1200 participants

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-12-13

Completion:

2032-09-07

Conditions

• Chronic Lymphocytic Leukemia
• Small Lymphocytic Lymphoma

Interventions

• DRUG

No Results Yet

NCT06121232 | ACTIVE_NOT_RECRUITING | NA

24 participants

Exploring the Benefit of Neuromodulation in Treating Chemo-induced Peripheral Neuropathy Using Peripheral Neuropathy Markers (Meissner's Corpuscles and Epidermal Nerve Fiber Density) and Sensory Testing (Quantitative Sensory and Gait Testing): A Single Center Feasibility Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-11-02

Completion:

2026-06-01

Conditions

• Neuropathy;Peripheral

Interventions

• DEVICE
• OTHER

No Results Yet

NCT06118554 | RECRUITING | NA

200 participants

3D Printing to Improve Nasal Irrigation Outcome

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2021-11-01

Completion:

2027-06-26

Conditions

• Chronic Rhinosinusitis With Nasal Polyps
• Chronic Rhinosinusitis Without Nasal Polyps

Interventions

• OTHER

No Results Yet

NCT06100393 | ACTIVE_NOT_RECRUITING | NA

150 participants

New Algorithms to Signal Processing for Speech Enhancement in Adult Cochlear Implant Recipients.

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-02-22

Completion:

2026-10-31

Conditions

• Hearing Loss

Interventions

• DEVICE

No Results Yet

NCT06099015 | RECRUITING

132 participants

Cera™ Vascular Plug System Post-Market Clinical Follow-Up

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2024-06-21

Completion:

2027-06-30

Conditions

• Aneurysm
• Endoleak
• Pulmonary Arteriovenous Malformation
• Portal Hypertension
• Arteriovenous Fistula
• Splenic Laceration

Interventions

• DEVICE

No Results Yet

NCT06096935 | COMPLETED

40 participants

Exome Evaluation in Patients Living With Diabetes Complicated by Charcot Neuroarthropathy.

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2024-07-11

Completion:

2025-01-18

Conditions

• Type 2 Diabetes

Interventions

• OTHER

No Results Yet

NCT06090916 | ACTIVE_NOT_RECRUITING | NA

100 participants

Malnutrition Screening and Dietary Intervention to Improve Nutrition Outcomes in Patients With Unresectable Pancreatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-01-17

Completion:

2027-03-31

Conditions

• Stage III Pancreatic Cancer
• Pancreatic Adenocarcinoma Non-resectable

Interventions

• OTHER

No Results Yet

NCT06090604 | COMPLETED | NA

33 participants

Walking Balance Training Post-Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-08-18

Completion:

2025-05-02

Conditions

• Stroke

Interventions

• OTHER

No Results Yet

NCT06089954 | ACTIVE_NOT_RECRUITING | NA

2500 participants

Penn Medicine Biobank Return of Results Program

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-10-20

Completion:

2026-07-01

Conditions

• Genetic Disease
• Cancer
• Cardiovascular Diseases

Interventions

• OTHER

No Results Yet

NCT06087445 | COMPLETED | NA

12 participants

A User-friendly, Non-invasive Neuro-orthosis That Restores Volitionally Controlled Grasp Functions for SCI Survivors With Tetraplegia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-10-31

Completion:

2026-05-11

Conditions

• Cervical Spinal Cord Injury

Interventions

• DEVICE

No Results Yet

NCT06077760 | RECRUITING | PHASE3

868 participants

A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-12-06

Completion:

2030-06-25

Conditions

• Non-small Cell Lung Cancer

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT06052267 | ACTIVE_NOT_RECRUITING | PHASE3

2772 participants

A Study to Test if a Fixed-Dose Combination of Fluticasone Propionate/Albuterol Sulfate is Effective in Preventing Asthma Exacerbations

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-08-30

Completion:

2026-10-31

Conditions

• Asthma

Interventions

• DRUG

No Results Yet

NCT06051695 | RECRUITING | PHASE1/PHASE2

474 participants

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-04-03

Completion:

2028-06-30

Conditions

• Rectal Cancer
• Cancer
• Solid Tumor, Adult
• Colorectal Cancer
• NSCLC
• Non Small Cell Lung Cancer
• NSCLC, Recurrent
• Non-Small Cell Squamous Lung Cancer
• Pancreas Cancer
• Pancreatic Neoplasm
• Colorectal Adenocarcinoma
• CRC
• Colon Cancer
• Ovarian Cancer
• Ovarian Neoplasms
• Mesothelioma
• Mesothelioma, Malignant
• Ovary Cancer
• Lung Cancer
• MESOM

Interventions

• BIOLOGICAL
• DIAGNOSTIC_TEST

No Results Yet

NCT06051617 | RECRUITING | PHASE3

318 participants

Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-09-07

Completion:

2030-08-31

Conditions

• Primary Biliary Cholangitis

Interventions

• DRUG

No Results Yet

NCT06046222 | ACTIVE_NOT_RECRUITING | PHASE2

45 participants

Trial of Efficacy and Safety of NS-229 Versus Placebo in Patients With Eosinophilic Granulomatosis With Polyangiitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-12-20

Completion:

2026-12-31

Conditions

• Eosinophilic Granulomatosis With Polyangiitis
• Churg-Strauss Syndrome

Interventions

• DRUG

No Results Yet