Clinical Trials

NCT06312176 | RECRUITING | PHASE3

1200 participants

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-04-14
Completion:: 2027-07-11

Conditions

Breast Neoplasms

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT06312137 | RECRUITING | PHASE3

780 participants

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-04-03
Completion:: 2034-02-21

Conditions

Non Small Cell Lung Cancer

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT06308978 | RECRUITING | PHASE1

244 participants

A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-03-28
Completion:: 2027-09-30

Conditions

Antineutrophilic Cytoplasmic Antibody (ANCA)- Associated Vasculitis (AAV)
Idiopathic Inflammatory Myositis (IIM)
Systemic Sclerosis (SSc)
Systemic Lupus Erythematosus (SLE)
Lupus Nephritis

Interventions

DRUG

No Results Yet

NCT06306443 | RECRUITING | PHASE3

240 participants

Buprenorphine for Individuals in Jail

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2025-07-01
Completion:: 2029-01-01

Conditions

Opioid Use Disorder

Interventions

DRUG

No Results Yet

NCT06303518 | RECRUITING | NA

100 participants

End Tidal Carbon Dioxide Concentration and Depth of Anesthesia in Children

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-06-25
Completion:: 2026-12-31

Conditions

Anesthesia
Hypercapnia
Hypocapnia

Interventions

OTHER

No Results Yet

NCT06292078 | RECRUITING | NA

5076 participants

Preventing School Exclusion and Opioid Misuse: Effectiveness of the Inclusive Skill-building Learning Approach (ISLA)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-04-15
Completion:: 2027-10-01

Conditions

Middle Schools
School Exclusion
School Community
Teaching Practices
Opioid and Other Substance Misuse

Interventions

BEHAVIORAL

No Results Yet

NCT06291818 | RECRUITING | NA

25 participants

Self-Adhering Magnetic Device to Treat Corneal Exposure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-04-17
Completion:: 2027-09-01

Conditions

Paralytic Lagophthalmos
Corneal Exposure

Interventions

DEVICE

No Results Yet

NCT06288828 | COMPLETED | NA

50 participants

The Efficacy of Aerobic Exercise Training on ANS and Endothelial Function in Compensated Cirrhosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-03-12
Completion:: 2025-08-15

Conditions

Cirrhosis
Aerobic Exercises
Lifestyle Modification
Endothelial Function
Autonomic Nervous System
Autonomic Dysfunction
Heart Rate Variability
Flow Mediated Dilation
Sarcopenia
Physical Activity
Physical Functional Performance
Physical Inactivity

Interventions

BEHAVIORAL

Results Available

NCT06287775 | RECRUITING | PHASE1/PHASE2

45 participants

Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2025-04-08
Completion:: 2029-07-25

Conditions

Extensive Stage Lung Small Cell Carcinoma
Stage IV Lung Cancer AJCC v8

Interventions

PROCEDURE
DRUG
BIOLOGICAL

No Results Yet

NCT06285526 | COMPLETED

78 participants

Glycocalyx Monitoring in Major Abdominal Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-22
Start Date:: 2022-07-05
Completion:: 2025-03-03

Conditions

Major Abdominal Surgery

Interventions

PROCEDURE

No Results Yet

NCT06280950 | RECRUITING | PHASE2

340 participants

Expanding Liver Transplant Immunosuppression Minimization Via Everolimus

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-09-12
Completion:: 2028-06-30

Conditions

Liver Transplant

Interventions

DRUG

No Results Yet

NCT06276387 | COMPLETED | NA

38 participants

Defining Stress REsilience And Mindfulness Effects in Rheumatoid Arthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-01-26
Completion:: 2025-01-01

Conditions

Arthritis, Rheumatoid

Interventions

BEHAVIORAL

Results Available

NCT06275724 | ACTIVE_NOT_RECRUITING

585 participants

Specified Drug-use Survey of Leqvio for s.c. Injection.

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-03-04
Completion:: 2026-12-17

Conditions

Familial Hypercholesterolaemia
Hypercholesterolaemia

Interventions

OTHER

No Results Yet

NCT06274775 | RECRUITING | NA

30 participants

Effect of an Educational Nail Biopsy Video on Pre-operative Anxiety, Health Literacy, and Patient Satisfaction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-04-02
Completion:: 2026-06-30

Conditions

Anxiety
Literacy
Satisfaction, Patient

Interventions

OTHER

No Results Yet

NCT06274619 | COMPLETED | NA

20 participants

Novel Mucosal Correlates Of RSV Protection In Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-03-13
Completion:: 2025-04-07

Conditions

Respiratory Tract Infections

Interventions

BIOLOGICAL

Results Available

NCT06271616 | TERMINATED | PHASE2

2 participants

Ibrutinib for the Prevention of Chronic Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplant

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-12-13
Completion:: 2026-05-14

Conditions

Chronic Graft Versus Host Disease
Hematopoietic and Lymphatic System Neoplasm

Interventions

PROCEDURE
DRUG

No Results Yet

NCT06270758 | RECRUITING

300 participants

Clinical Validation of BBCT-hip

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-22
Start Date:: 2023-11-07
Completion:: 2030-11-06

Conditions

Osteoporosis

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06266390 | ACTIVE_NOT_RECRUITING | NA

54 participants

Individualized (fMRI-guided) TMS Treatment for Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-05-29
Completion:: 2026-04-14

Conditions

Depression
Major Depressive Disorder
Persistent Depressive Disorder

Interventions

DEVICE

No Results Yet

NCT06263088 | RECRUITING | NA

200 participants

EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-12-01
Completion:: 2026-09-30

Conditions

Gastrointestinal Cancer
Colon Cancer
Rectal Cancer
Anal Cancer
Esophageal Cancer
Stomach Cancer
Appendix Cancer
Pancreas Cancer
Liver Cancer
Neuroendocrine Tumors

Interventions

OTHER

No Results Yet

NCT06253858 | RECRUITING | NA

10 participants

Ultrasound (US) Guided External Ventricular Catheter Placement

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2026-05-31
Completion:: 2026-12-01

Conditions

Hydrocephalus

Interventions

DEVICE

No Results Yet

NCT06249776 | COMPLETED | NA

55 participants

Gravity Stent-Retriever System For Reperfusion Of Large Vessel Occlusion Stroke Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-02-09
Completion:: 2026-04-14

Conditions

Ischemic Stroke
Stroke
Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Vascular Diseases
Cardiovascular Diseases

Interventions

DEVICE

No Results Yet

NCT06246123 | RECRUITING

2040 participants

A Study of Jyseleca Tablet (Filgotinib Maleate) in Korean Participants

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-02-27
Completion:: 2027-07-30

Conditions

Arthritis, Rheumatoid
Colitis, Ulcerative

Interventions

OTHER

No Results Yet

NCT06238817 | COMPLETED | PHASE3

241 participants

A Study to Evaluate the Efficacy, and Safety Study of Ruxolitinib Cream in Adults With Moderate Atopic Dermatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-04-26
Completion:: 2025-05-21

Conditions

Atopic Dermatitis

Interventions

DRUG

Results Available

NCT06238479 | ACTIVE_NOT_RECRUITING | PHASE1

490 participants

A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-03-05
Completion:: 2027-03-31

Conditions

Metastatic Solid Tumor
Recurrent Solid Tumor
Advanced Solid Tumor
Urinary Bladder Neoplasm
Triple Negative Breast Cancer
Non-small Cell Lung Cancer
Esophageal Cancer
Pancreatic Cancer
Ovarian Cancer
Cervical Cancer
Head and Neck Squamous Cell Carcinoma
Prostate Cancer
Renal Pelvis Cancer
Bladder Cancer

Interventions

DRUG

No Results Yet

NCT06230757 | COMPLETED | PHASE2

20 participants

Psilocybin for Treatment-Resistant Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-07-08
Completion:: 2026-05-08

Conditions

Major Depressive Disorder
Anhedonia
Treatment Resistant Depression

Interventions

DRUG

No Results Yet

NCT06229496 | RECRUITING | PHASE1

70 participants

Dose Escalation and Dose Expansion Study of GAS in Subjects With Metastatic Pancreatic Adenocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2023-08-01
Completion:: 2027-12-31

Conditions

Metastatic Pancreatic Adenocarcinoma

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06226883 | RECRUITING | PHASE2

385 participants

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-07-18
Completion:: 2028-09-30

Conditions

Inflammatory Bowel Diseases
Crohn's Disease

Interventions

DRUG

No Results Yet

NCT06222034 | RECRUITING | PHASE1

10 participants

Study to Measure Filgotinib in the Blood of Children and Teenagers With Arthritis Taking Filgotinib (SCALESIA)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-05-13
Completion:: 2026-08-31

Conditions

Juvenile Idiopathic Arthritis

Interventions

DRUG

No Results Yet

NCT06221267 | COMPLETED

120 participants

A Registry Study on Rimegepant for the Treatment of Migraine Participants in Guangdong-Hong Kong-Macao Greater Bay Area

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-01-26
Completion:: 2024-06-30

Conditions

Migraine

Interventions

DRUG

No Results Yet

NCT06221111 | COMPLETED | PHASE2

39 participants

Comparison of Rimegepant and Placebo for Pain in IBS

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-06-06
Completion:: 2025-05-30

Conditions

Irritable Bowel Syndrome

Interventions

DRUG

Results Available

NCT06215118 | RECRUITING | PHASE1

87 participants

A Study to Learn About the Effects of the Combination of Elranatamab (PF-06863135) and Iberdomide in Patients With Relapsed or Refractory Multiple Myeloma (MagnetisMM-30)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-02-20
Completion:: 2027-04-10

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT06214286 | COMPLETED | NA

100 participants

ESWT Imorove Pain and Function in Carpal Tunnel

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-04-10
Completion:: 2024-11-20

Conditions

Physiopathology

Interventions

DEVICE
OTHER

No Results Yet

NCT06209684 | RECRUITING | NA

118 participants

Carbofix Pedicle Screw System: Evaluation of the Clinical and Radiographic Outcomes of the Use of a Carbon Fiber Device Compared to Titanium Devices in Patients Undergoing Spinal Arthrodesis for Degenerative Spinal Diseases

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2022-04-29
Completion:: 2026-09-29

Conditions

Degenerative Disc Disease

Interventions

PROCEDURE

No Results Yet

NCT06209359 | RECRUITING | PHASE1

50 participants

Mechanisms of Diuretic Resistance in Heart Failure, Aim 3

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-07-24
Completion:: 2029-03-01

Conditions

Heart Failure
Diuretic Resistance

Interventions

DRUG

No Results Yet

NCT06208696 | COMPLETED | NA

47 participants

Chronic-disease Self-management Program in Patients Living With Long-COVID in Puerto Rico

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2023-11-02
Completion:: 2024-02-29

Conditions

Long Covid19

Interventions

OTHER

Results Available

NCT06197568 | RECRUITING | PHASE2

90 participants

Proof of Concept Study of Vaginal AZU-101 in Vulvovaginal Atrophy in Postmenopausal Women

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2026-06-01
Completion:: 2026-12-31

Conditions

Vulvo Vaginal Atrophy (VVA)

Interventions

DRUG

No Results Yet

NCT06197425 | RECRUITING | PHASE3

1660 participants

Investigate the Efficacy of Chemotherapy in Patients With Positive ctDNA After Surgery and Adjuvant Chemotherapy for a Stage III Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2026-05-07
Completion:: 2032-05-31

Conditions

Colon or Upper Rectum Adenocarcinoma

Interventions

DRUG
BIOLOGICAL
OTHER

No Results Yet

NCT06193642 | COMPLETED | NA

33 participants

Increasing Knowledge on Osteogenesis Imperfecta by Collecting Epidemiological Data

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2023-01-20
Completion:: 2024-11-30

Conditions

Osteogenesis Imperfecta

Interventions

OTHER

No Results Yet

NCT06189092 | RECRUITING

65 participants

Treatment of Low-flow Venous Malformations With Electrosclerotherapy. Prospective Observational Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-22
Start Date:: 2023-10-28
Completion:: 2026-11-28

Conditions

Vascular Malformations

Interventions

DRUG

No Results Yet

NCT06188559 | COMPLETED | PHASE2

56 participants

A Study of BB-1701 in Previously Treated Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive or HER2-low Unresectable or Metastatic Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-22
Start Date:: 2024-04-10
Completion:: 2026-03-18

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet