Clinical Trials

NCT06885424 | ENROLLING_BY_INVITATION

400 participants

A Long-Term Follow-Up Study of Participants Treated With A2 Biotherapeutics (A2 Bio) Gene Therapy (GT) Products

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-07-31
Completion:: 2030-03-31

Conditions

Solid Tumor Cancer
Solid Tumor, Unspecified, Adult
Colorectal Carcinoma
Colorectal Carcinoma (CRC)
Non Small Cell Lung Cancer
Small Cell Lung Cancer ( SCLC )
Pancreatic Cancer
NSCLC
Mesothelioma
Ovarian Cancer
Ovarian Carcinoma
Head and Neck (HNSCC)
Head and Neck Cancer
Renal Cell Carcinoma (Kidney Cancer)
Triple Negative Breast Cancer (TNBC)

Interventions

OTHER

No Results Yet

NCT06884800 | COMPLETED | NA

100 participants

Laparoscopic Toupet's Fundoplication: Is it Proper Solution of Radiological Negative, Endoscopically Positive Hiatal Hernia Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2024-10-01
Completion:: 2026-03-31

Conditions

Laparoscopic Toupet Fundoplication
Radiological Negative
Endoscope
Hiatal Hernia

Interventions

PROCEDURE

No Results Yet

NCT06878859 | RECRUITING | NA

80 participants

Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2026-02-23
Completion:: 2028-01-31

Conditions

Depression - Major Depressive Disorder
Cannabis Use Disorder
Mental Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06871579 | RECRUITING | NA

25 participants

Study of the Esophageal String Test (EST) for the Diagnosis of Helicobacter Pylori

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-06-11
Completion:: 2027-01-30

Conditions

Helicobacter Pylori

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06868290 | RECRUITING | PHASE2

126 participants

Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Severe Active GPA or MPA

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-03-13
Completion:: 2029-06-07

Conditions

ANCA Associated Vasculitis (AAV)

Interventions

BIOLOGICAL
OTHER
DRUG

No Results Yet

NCT06863402 | RECRUITING | PHASE2

32 participants

Nemtabrutinib and Pembrolizumab for the Treatment of Richter Transformation, Diffuse Large B-cell Lymphoma Subtype

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2026-06-15
Completion:: 2029-06-01

Conditions

Richter Syndrome
Diffuse Large B-Cell Lymphoma
Chronic Lymphocytic Leukemia

Interventions

PROCEDURE
DRUG
BIOLOGICAL
OTHER

No Results Yet

NCT06862167 | COMPLETED | NA

200 participants

Desarda's Technique Versus Lichtenstein's Technique Hernia Repair in Management of Elective Non-Complicated Inguinal Hernia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2018-08-01
Completion:: 2020-08-31

Conditions

Desarda's Technique
Lichtenstein's Technique
Hernia Repair
Inguinal Hernia

Interventions

PROCEDURE

No Results Yet

NCT06860815 | RECRUITING | PHASE2

11 participants

Cemiplimab and Transarterial Radioembolization With Y-90 SIR-S Spheres for the Treatment of Liver Directed Metastatic Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2026-01-30
Completion:: 2027-01-30

Conditions

Anatomic Stage IV Breast Cancer AJCC v8
Metastatic Breast Carcinoma
Metastatic Carcinoma in the Liver

Interventions

PROCEDURE
BIOLOGICAL
RADIATION

No Results Yet

NCT06855758 | RECRUITING | NA

150 participants

Effect of Terlipressin for Intraoperative Blood Pressure Management in Kidney Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-03-06
Completion:: 2027-06-30

Conditions

Kidney Transplant
Delayed Graft Function
Intraoperative Hypotension

Interventions

DRUG

No Results Yet

NCT06855212 | ACTIVE_NOT_RECRUITING | PHASE2

22 participants

Phase II Study of Neoadjuvant Cetuximab and Cemiplimab in Patients Undergoing Surgery for HNSCC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-02-26
Completion:: 2028-03-31

Conditions

Head and Neck Squamous Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT06853886 | RECRUITING | NA

140 participants

Gene Discovery in CHB Patients to Identify Unknown Pathways That Lead to B and NK Cell Deregulation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-08-12
Completion:: 2028-10-01

Conditions

Chronic Hepatitis B Virus

Interventions

OTHER

No Results Yet

NCT06849349 | COMPLETED

48 participants

Placenta Previa and Placenta Percreta Patients During the Third Trimester

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-02-20
Completion:: 2025-06-20

Conditions

Placenta Percreta, Third Trimester
Placenta Previa

No Results Yet

NCT06844981 | RECRUITING | NA

40 participants

Effects of Latin Dancing on Sleep Quality in Hispanic Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2026-04-01
Completion:: 2026-12-31

Conditions

Cancer Survivorship
Sleep Disturbances

Interventions

BEHAVIORAL

No Results Yet

NCT06844344 | RECRUITING | NA

100 participants

Diagnosing peRipheral Lung Lesions With CRYO Biopsies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-03-01
Completion:: 2027-02-01

Conditions

Lung Cancer
Peripheral Lung Lesions

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06837454 | RECRUITING

600 participants

French Prospective Observational Study in Patients Eligible for Systemic Therapy for Atopic Dermatitis (AD)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-02-04
Completion:: 2027-05-13

Conditions

Atopic Dermatitis

No Results Yet

NCT06834360 | RECRUITING | PHASE3

210 participants

A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-02-06
Completion:: 2027-01-08

Conditions

Chronic Rhinosinusitis With Nasal Polyps

Interventions

DRUG

No Results Yet

NCT06834347 | ACTIVE_NOT_RECRUITING | PHASE3

231 participants

A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-02-12
Completion:: 2026-10-14

Conditions

Chronic Rhinosinusitis With Nasal Polyps

Interventions

DRUG

No Results Yet

NCT06833957 | RECRUITING

18100 participants

Preparing for Maternal GBS Vaccine Trials in Africa

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-03-01
Completion:: 2027-02-28

Conditions

Group B Streptococcus
Invasive Bacterial Diseases (IBD)
Maternal Immunization

No Results Yet

NCT06828887 | RECRUITING | PHASE2

400 participants

Dose-Finding Clinical Trial to Evaluate the Efficacy and Safety of LV232 Capsules in the Treatment of MDD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-04-03
Completion:: 2026-09-01

Conditions

MDD

Interventions

DRUG

No Results Yet

NCT06822426 | RECRUITING | PHASE3

200 participants

Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-05-14
Completion:: 2028-01-31

Conditions

Central Line Associated Blood Stream Infections (CLABSI)

Interventions

DRUG

No Results Yet

NCT06820385 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated:: 2026-05-20

No Results Yet

NCT06817720 | RECRUITING | PHASE2

50 participants

Phase II Study Assessing the Efficacy and Toxicity of Olverembatinib Monotherapy in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-10-13
Completion:: 2027-03-07

Conditions

Chronic Myeloid Leukemia

Interventions

DRUG

No Results Yet

NCT06816433 | SUSPENDED | PHASE2

200 participants

Department of Defense PTSD Adaptive Platform Trial - Intervention D - SLS-002

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2028-05-31
Completion:: 2029-05-31

Conditions

Post Traumatic Stress Disorder

Interventions

DRUG

No Results Yet

NCT06814496 | RECRUITING | PHASE1/PHASE2

30 participants

Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-09-08
Completion:: 2030-05-31

Conditions

Melanoma
Medullary Thyroid Cancer
Sinonasal Undifferentiated Carcinoma
Esthesioneuroblastoma
Bladder Cancer
Testicular Cancer
Glioblastoma Multiforme
Cervical Cancer
Large Cell Neuroendocrine Carcinoma of the Lung
Non Small Cell Lung Cancer
Merkel Cell Carcinoma

Interventions

DRUG
RADIATION

No Results Yet

NCT06812260 | ACTIVE_NOT_RECRUITING | PHASE2

26 participants

A Single-arm, Open-label, Phase II Study to Evaluate Efficacy, Safety and Pharmacokinetics of HLX10 + Chemotherapy in Patients With ES-SCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-06-24
Completion:: 2026-10-22

Conditions

SCLC, Extensive Stage

Interventions

DRUG

No Results Yet

NCT06809686 | RECRUITING

1000 participants

Study to Collect High-Resolution ECG Data and Patient Insights on Heart Failure Care

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-02-05
Completion:: 2027-01-21

Conditions

Heart Failure

No Results Yet

NCT06808217 | ACTIVE_NOT_RECRUITING

550 participants

A Registry on the FARAVIEW Technology of the OPAL HDx Mapping System When Used With the FARAWAVE NAV Ablation Catheter in the Treatment of Atrial Fibrillation

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-07-30
Completion:: 2027-04-01

Conditions

Atrial Fibrillation
Pulsed Field Ablation
FARAPULSE

Interventions

DEVICE

No Results Yet

NCT06806852 | ACTIVE_NOT_RECRUITING | PHASE1

85 participants

A Study to Test Whether Treatment With BI 770371 in Combination With Pembrolizumab With or Without Cetuximab Helps People With Head and Neck Cancer Compared With Pembrolizumab Alone

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-05-14
Completion:: 2027-08-31

Conditions

Head and Neck Squamous Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT06803862 | ACTIVE_NOT_RECRUITING

21783 participants

RegiStry Of the multiFaceted medIcal cenTer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-20
Start Date:: 2021-01-01
Completion:: 2026-12-31

Conditions

Chronic Non-communicable Diseases
Cardiovascular Diseases
COVID-19
Multimorbidity

No Results Yet

NCT06801834 | RECRUITING | PHASE3

695 participants

Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-04-04
Completion:: 2029-10-31

Conditions

Extensive Stage Small Cell Lung Cancer (ES-SCLC)

Interventions

DRUG

No Results Yet

NCT06797635 | RECRUITING | PHASE2

372 participants

Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-03-20
Completion:: 2029-12-31

Conditions

Breast Neoplasms
Breast Cancer

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06796504 | RECRUITING | NA

60 participants

The SetPoint System as a Pro-Remyelination Therapy for Relapsing-Remitting Multiple Sclerosis: A Pilot Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2026-04-17
Completion:: 2027-12-31

Conditions

Relapsing Remitting Multiple Sclerosis

Interventions

PROCEDURE
DRUG
DEVICE

No Results Yet

NCT06793280 | COMPLETED | NA

562 participants

Evaluation of Colonic Perfusion by Indocyanine Green Angiography During Colorectal Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2022-02-22
Completion:: 2025-12-01

Conditions

Anastomotic Leak

Interventions

PROCEDURE

No Results Yet

NCT06787612 | RECRUITING | PHASE2

220 participants

Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-05-28
Completion:: 2028-10-30

Conditions

Ovarian Cancer
Fallopian Tube Cancer
Primary Peritoneal Cancer

Interventions

DRUG

No Results Yet

NCT06773403 | TERMINATED | PHASE4

5 participants

Upadacitinib for Prurigo Nodularis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2024-04-09
Completion:: 2025-06-06

Conditions

Prurigo Nodularis

Interventions

DRUG

No Results Yet

NCT06768164 | RECRUITING | PHASE3

250 participants

Quality of Life After Billroth II or Roux-en-Y for Gastric Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2026-03-20
Completion:: 2031-04-30

Conditions

Gastric (Cardia, Body) Cancer

Interventions

PROCEDURE

No Results Yet

NCT06747117 | RECRUITING

300 participants

A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-05-18
Completion:: 2028-06-30

Conditions

Lower Extremity Acute Limb Ischemia
LE ALI

Interventions

DEVICE

No Results Yet

NCT06742190 | ACTIVE_NOT_RECRUITING | PHASE3

154 participants

A Study to Assess the Efficacy and Safety of Empasiprubart Versus IVIg in Adults With Multifocal Motor Neuropathy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2024-12-18
Completion:: 2026-09-30

Conditions

Multifocal Motor Neuropathy (MMN)
MMN

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT06739707 | SUSPENDED | PHASE1

54 participants

Subcutaneously Administered MD-18 for the Treatment of Obesity and Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-01-02
Completion:: 2026-12-31

Conditions

Healthy Volunteer

Interventions

DRUG

No Results Yet

NCT06736600 | ACTIVE_NOT_RECRUITING | NA

33 participants

Patient-identified Values as Outcome Targets (PIVOT) Feasibility Pilot Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-20
Start Date:: 2025-04-18
Completion:: 2027-08-31

Conditions

Peripheral Neuropathy Due to Chemotherapy

Interventions

BEHAVIORAL

No Results Yet