Clinical Trials

NCT05161663 | COMPLETED | NA

98 participants

A Peer-Driven Intervention to Increase PrEP Uptake Among Minority MSM

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2022-07-01

Completion:

2024-12-23

Conditions

• HIV Infections

Interventions

• BEHAVIORAL

Results Available

NCT05152147 | ACTIVE_NOT_RECRUITING | PHASE3

920 participants

A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-12-02

Completion:

2026-07-31

Conditions

• Gastric Neoplasms
• Gastroesophageal Adenocarcinoma
• Esophageal Adenocarcinoma

Interventions

• DRUG

No Results Yet

NCT05149755 | ACTIVE_NOT_RECRUITING | NA

650 participants

Evolut™ EXPAND TAVR II Pivotal Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2022-04-27

Completion:

2027-09-30

Conditions

• Moderate Aortic Valve Stenosis

Interventions

• DEVICE

No Results Yet

NCT05146297 | COMPLETED | NA

585 participants

Diversity and Inclusion in Research Underpinning Prevention and Therapy Trials

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2023-04-23

Completion:

2026-04-15

Conditions

• Breast Cancer
• Liver Cancer
• Prostate Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT05136196 | RECRUITING | PHASE2

150 participants

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2022-12-06

Completion:

2027-01-01

Conditions

• Clinical Stage III Cutaneous Melanoma AJCC v8
• Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Clinical Stage IV Cutaneous Melanoma AJCC v8
• Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Locally Recurrent Head and Neck Squamous Cell Carcinoma
• Locally Recurrent Hypopharyngeal Squamous Cell Carcinoma
• Locally Recurrent Laryngeal Squamous Cell Carcinoma
• Locally Recurrent Oral Cavity Squamous Cell Carcinoma
• Locally Recurrent Oropharyngeal Squamous Cell Carcinoma
• Metastatic Head and Neck Squamous Cell Carcinoma
• Metastatic Hypopharyngeal Squamous Cell Carcinoma
• Metastatic Laryngeal Squamous Cell Carcinoma
• Metastatic Melanoma
• Metastatic Oral Cavity Squamous Cell Carcinoma
• Metastatic Oropharyngeal Squamous Cell Carcinoma
• Recurrent Melanoma
• Stage III Hypopharyngeal Carcinoma AJCC v8
• Stage III Laryngeal Cancer AJCC v8
• Stage III Lip and Oral Cavity Cancer AJCC v8
• Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8
• Stage IV Hypopharyngeal Carcinoma AJCC v8
• Stage IV Laryngeal Cancer AJCC v8
• Stage IV Lip and Oral Cavity Cancer AJCC v8
• Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8
• Unresectable Melanoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet

NCT05130528 | COMPLETED | NA

11 participants

Therapeutic Intervention Supporting Development From NICU to 6 Months for Infants Post Hypoxic-Ischemic Encephalopathy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2022-02-18

Completion:

2024-04-30

Conditions

• Cerebral Palsy
• Hypoxic-Ischemic Encephalopathy

Interventions

• BEHAVIORAL

Results Available

NCT05119569 | ACTIVE_NOT_RECRUITING | PHASE2

109 participants

A Study to Investigate the Efficacy of Fenebrutinib in Relapsing Multiple Sclerosis (RMS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2022-03-01

Completion:

2023-03-29

Conditions

• Relapsing Multiple Sclerosis

Interventions

• DRUG

Results Available

NCT05119387 | RECRUITING

1200 participants

Genetic Study of Amyotrophic Lateral Sclerosis in Norway

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2019-08-01

Completion:

2030-12-31

Conditions

• Amyotrophic Lateral Sclerosis

Interventions

• OTHER

No Results Yet

NCT05110651 | WITHDRAWN | PHASE4

0 participants

The Danish Pre-HCQ COVID Dialysis Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2020-04-10

Completion:

2020-07-31

Conditions

• COVID-19
• End Stage Renal Disease

Interventions

• DRUG

No Results Yet

NCT05095376 | ACTIVE_NOT_RECRUITING | PHASE3

265 participants

Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2022-03-28

Completion:

2026-02-12

Conditions

• Glioblastoma
• Gliosarcoma

Interventions

• DRUG
• PROCEDURE
• RADIATION
• OTHER

No Results Yet

NCT05090540 | ENROLLING_BY_INVITATION

600 participants

Transcatheter Versus Standard Surgical Mitral Valve Operation for Secondary Mitral Regurgitation

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2017-06-01

Completion:

2024-03-01

Conditions

• Severe Mitral Valve Regurgitation (Disorder)

Interventions

• DEVICE
• PROCEDURE

No Results Yet

NCT05081245 | COMPLETED | PHASE2

168 participants

ML-004 in Adolescents and Adults With Autism Spectrum Disorders (ASD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2022-09-13

Completion:

2026-03-10

Conditions

• Autism Spectrum Disorder

Interventions

• DRUG

No Results Yet

NCT05077904 | RECRUITING | PHASE3

350 participants

A Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-12-07

Completion:

2026-06-30

Conditions

• Stereotypical Prolonged Seizures

Interventions

• DRUG
• OTHER

No Results Yet

NCT05076006 | COMPLETED | PHASE2

51 participants

Dual JAK1/TYK2 Inhibitor for Cicatricial Alopecia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-05-19

Completion:

2023-09-30

Conditions

• Cicatricial Alopecia

Interventions

• DRUG

Results Available

NCT05064631 | COMPLETED | PHASE2

173 participants

Bacterial Lysate In Preventing Asthma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2022-01-12

Completion:

2024-06-13

Conditions

• Respiratory Tract Infections
• Pediatric Respiratory Diseases
• Wheezing

Interventions

• DRUG

No Results Yet

NCT05062629 | COMPLETED

29 participants

United States Hypophosphatasia Molecular Research Center

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2021-08-24

Completion:

2026-02-25

Conditions

• Hypophosphatasia

Interventions

• GENETIC

No Results Yet

NCT05057494 | ACTIVE_NOT_RECRUITING | PHASE3

607 participants

A Study of Acalabrutinib Plus Venetoclax Versus Venetoclax Plus Obinutuzumab in Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2022-09-12

Completion:

2027-07-15

Conditions

• Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Interventions

• DRUG

No Results Yet

NCT05038358 | RECRUITING

60 participants

Tumor Immune Microenvironment Involvement in Colorectal Cancer Chemoresistance Mechanisms

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2022-12-12

Completion:

2028-09-30

Conditions

• Primary Tumor
• Colon Tumor

No Results Yet

NCT05032820 | COMPLETED | PHASE2

40 participants

Upfront Chimeric Antigen Receptor T-Cell to Upgrade Response in Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2022-01-05

Completion:

2024-08-22

Conditions

• Multiple Myeloma

Interventions

• DRUG
• BIOLOGICAL
• PROCEDURE

Results Available

NCT05030207 | RECRUITING | NA

30 participants

Respiratory Adaptive Computed Tomography: Feasibility Study on Real-Time Gated 4DCT for Lung Cancer Radiotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2024-05-15

Completion:

2026-12-31

Conditions

• Lung Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05011266 | RECRUITING | PHASE2/PHASE3

180 participants

Efficacy of Buprenorphine and XR-Naltrexone Combination for Relapse Prevention in Opioid Use Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2023-04-18

Completion:

2027-01-01

Conditions

• Opioid-use Disorder

Interventions

• DRUG

No Results Yet

NCT05004857 | ACTIVE_NOT_RECRUITING | NA

1 participants

The Effect of Reading Therapy on Newborns

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-09-17

Completion:

2027-12-31

Conditions

• Autonomic Nervous System Diseases

Interventions

• BEHAVIORAL

No Results Yet

NCT04966481 | RECRUITING | PHASE3

81 participants

Palbociclib and Cetuximab Versus Cetuximab Monotherapy for Patients With CDKN2A-altered, HPV-unrelated Head and Neck Squamous Cell Carcinoma Who Experienced Disease Progression on a PD-1/L1 Inhibitor

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2022-04-06

Completion:

2028-02-28

Conditions

• HPV-unrelated Head and Neck Squamous Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT04956445 | RECRUITING

2000 participants

Collection of SARS CoV-2 (COVID-19) Virus Secretions and Serum for Countermeasure Development

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2020-03-17

Completion:

2027-12-31

Conditions

• Covid19

No Results Yet

NCT04935359 | COMPLETED | PHASE3

511 participants

Study of Efficacy and Safety of NIS793 in Combination With Standard of Care (SOC) Chemotherapy in First-line Metastatic Pancreatic Ductal Adenocarcinoma (mPDAC) - daNIS-2

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-09-30

Completion:

2024-08-13

Conditions

• Metastatic Pancreatic Ductal Adenocarcinoma

Interventions

• DRUG

Results Available

NCT04916951 | COMPLETED | PHASE1

72 participants

Oral Amoxicillin and Cephalexin PK/PD in Neonates

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-07-14

Completion:

2025-11-30

Conditions

• Neonatal Infection

Interventions

• DRUG

No Results Yet

NCT04916730 | ACTIVE_NOT_RECRUITING | NA

61 participants

Effect of Time-restricted Eating on Catecholamine-sensitivity of Adipose Tissue in Obese Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2020-12-17

Completion:

2023-05-26

Conditions

• Obesity

Interventions

• BEHAVIORAL

Results Available

NCT04914611 | RECRUITING

10000 participants

Real World Assessment of People Living With Chronic Hepatitis B in Australia

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2022-02-17

Completion:

2030-07-31

Conditions

• Hepatitis B

Interventions

• OTHER

No Results Yet

NCT04903080 | ACTIVE_NOT_RECRUITING | PHASE1

50 participants

HER2-specific Chimeric Antigen Receptor (CAR) T Cells for Children With Ependymoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2022-07-27

Completion:

2026-06-30

Conditions

• Ependymoma

Interventions

• BIOLOGICAL

No Results Yet

NCT04902833 | COMPLETED

18 participants

Acquired Pyruvate Kinase Deficiency In Clonal Myeloid Neoplasms

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2022-02-01

Completion:

2026-02-01

Conditions

• Pyruvate Kinase Deficiency
• Pyruvate Kinase Deficiency Anemia
• Hereditary Hemolytic Anemia
• Myelodysplastic Syndromes
• Myelodysplastic/Myeloproliferative Neoplasm
• Clonal Myeloid Neoplasm
• Myeloproliferative Neoplasm
• Acute Myeloid Leukemia
• Clonal Cytopenia of Undetermined Significance
• Other Clonal Myeloid Neoplasm
• Unexplained Coombs-negative Non-immune Hemolytic Anemia

Interventions

• PROCEDURE

No Results Yet

NCT04901702 | RECRUITING | PHASE1/PHASE2

90 participants

Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-06-09

Completion:

2026-12-31

Conditions

• Recurrent Solid Tumor
• Recurrent Ewing Sarcoma
• Recurrent Hepatoblastoma
• Recurrent Malignant Germ Cell Tumor
• Recurrent Malignant Solid Neoplasm
• Recurrent Neuroblastoma
• Recurrent Osteosarcoma
• Recurrent Peripheral Primitive Neuroectodermal Tumor
• Recurrent Rhabdoid Tumor
• Recurrent Rhabdomyosarcoma
• Recurrent Soft Tissue Sarcoma
• Recurrent Wilms Tumor
• Refractory Ewing Sarcoma
• Refractory Hepatoblastoma
• Refractory Malignant Germ Cell Tumor
• Refractory Malignant Solid Neoplasm
• Refractory Neuroblastoma
• Refractory Osteosarcoma
• Refractory Peripheral Primitive Neuroectodermal Tumor
• Refractory Rhabdoid Tumor
• Refractory Rhabdomyosarcoma
• Refractory Soft Tissue Sarcoma

Interventions

• DRUG

No Results Yet

NCT04899661 | ACTIVE_NOT_RECRUITING

1081 participants

A Study to Learn More About the Long-term Safety and Effectiveness of Molidustat as a Treatment for Japanese Men and Women With Renal Anemia

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2021-08-06

Completion:

2027-06-30

Conditions

• Renal Anemia

Interventions

• DRUG

No Results Yet

NCT04897321 | RECRUITING | PHASE1

48 participants

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2022-07-06

Completion:

2027-03-01

Conditions

• Pediatric Solid Tumor
• Osteosarcoma
• Rhabdomyosarcoma
• Neuroblastoma
• Ewing Sarcoma
• Wilms Tumor
• Adrenocortical Cancer
• Desmoplastic Small Round Cell Tumor
• Germ Cell Cancer
• Rhabdoid Tumor
• Clear Cell Sarcoma
• Hepatoblastoma
• Melanoma
• Carcinoma
• Malignant Peripheral Nerve Sheath Tumors
• Soft Tissue Sarcoma

Interventions

• DRUG

No Results Yet

NCT04889924 | RECRUITING | NA

820 participants

ALND vs ART in Positive Sentinel Node After Neoadjuvant Therapy in Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-06-11

Completion:

2026-06-30

Conditions

• Breast Cancer
• Chemotherapy
• Sentinel Lymph Node
• Axillary Lymph Nodes Dissection
• Radiotherapy Side Effect

Interventions

• RADIATION
• PROCEDURE

No Results Yet

NCT04876963 | COMPLETED

268 participants

HOLT-ED: Holter-monitoring in End-stage Renal Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2021-09-01

Completion:

2025-12-31

Conditions

• Kidney Failure, Chronic
• Arrhythmias, Cardiac
• Heart Diseases
• Cardiovascular Diseases
• Kidney Diseases
• Renal Insufficiency, Chronic
• Renal Insufficiency

Interventions

• DEVICE

No Results Yet

NCT04873245 | ACTIVE_NOT_RECRUITING | PHASE2

120 participants

Lifestyle Counseling and Medication for Adolescent Weight Management

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2022-03-15

Completion:

2026-06-30

Conditions

• Obesity, Childhood

Interventions

• BEHAVIORAL
• DRUG

No Results Yet

NCT04862052 | COMPLETED | NA

108 participants

Optimal Treatment for Coronary Drug Eluting Stent In-stent Restenosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-04-26

Completion:

2025-01-30

Conditions

• Coronary Stent Restenosis

Interventions

• PROCEDURE

No Results Yet

NCT04846309 | RECRUITING | PHASE1

16 participants

Hypoxia Imaging for Esophageal Cancer to Guide Personalized Radiation Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-10-12

Completion:

2026-10-31

Conditions

• Esophageal Cancer

Interventions

• RADIATION
• DRUG

No Results Yet

NCT04834635 | COMPLETED | NA

1000 participants

The FundoRingOAGB Versus Non-wrapping (Non-banded) Standard Method of Laparoscopic One Anastomosis Gastric Bypass

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-03-29

Completion:

2024-04-05

Conditions

• Obesity, Morbid

Interventions

• PROCEDURE

No Results Yet

NCT04828902 | COMPLETED

610 participants

Incidence of Postoperative Delirium After Cardiac Surgery in Adults.

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2021-02-01

Completion:

2021-12-31

Conditions

• Postoperative Delirium
• Adult Cardiac Surgery
• Covid19

Interventions

• PROCEDURE

No Results Yet