Clinical Trials

NCT04163432 | ACTIVE_NOT_RECRUITING | PHASE2

43 participants

Staggered, Chemo-Immunotherapy With Durvalumab, MEDI4736 Pemetrexed & Carboplatin (PC) for Metastatic Non-Squamous NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2020-06-16

Completion:

2025-02-04

Conditions

• Non-Small Cell Lung Cancer Metastatic

Interventions

• DRUG

Results Available

NCT04158141 | TERMINATED | PHASE3

16 participants

Testing the Addition of Targeted Radiation Therapy to Surgery and the Usual Chemotherapy Treatment (Pemetrexed and Cisplatin [or Carboplatin]) for Stage I-IIIA Malignant Pleural Mesothelioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2020-01-29

Completion:

2023-11-20

Conditions

• Pleural Biphasic Mesothelioma
• Pleural Epithelioid Mesothelioma
• Stage I Pleural Malignant Mesothelioma AJCC v8
• Stage IA Pleural Malignant Mesothelioma AJCC v8
• Stage IB Pleural Malignant Mesothelioma AJCC v8
• Stage II Pleural Malignant Mesothelioma AJCC v8
• Stage IIIA Pleural Malignant Mesothelioma AJCC v8

Interventions

• DRUG
• PROCEDURE
• RADIATION

Results Available

NCT04141644 | ACTIVE_NOT_RECRUITING | PHASE1

24 participants

Safety and Efficacy of Combination Osimertinib and Ipilimumab in Patients w EGFR Mutated NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2020-08-20

Completion:

2024-01-29

Conditions

• Non-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor Receptor (Disorder)

Interventions

• DRUG

No Results Yet

NCT04130542 | COMPLETED | PHASE1

105 participants

Phase 1 Trial of LVGN6051 as Single Agent and in Combination With Keytruda (Pembrolizumab) in Advanced or Metastatic Malignancy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2019-10-31

Completion:

2025-12-31

Conditions

• Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT04122001 | ACTIVE_NOT_RECRUITING | NA

90 participants

Effects of Electrical Stimulation on Verbal Learning in Typical and Atypical Alzheimer's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2020-08-17

Completion:

2026-10-30

Conditions

• Alzheimer Disease, Early Onset
• Atypical Alzheimer's Disease
• Logopenic Progressive Aphasia

Interventions

• DEVICE
• OTHER

No Results Yet

NCT04117074 | COMPLETED | PHASE3

106 participants

Thoracic Epidural Analgesia vs Surgical Site Infiltration With Liposomal Bupivacaine Following Open Gynecologic Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-04-14

Completion:

2025-03-03

Conditions

• Surgery
• Analgesia

Interventions

• DRUG
• OTHER

Results Available

NCT04106518 | RECRUITING

447 participants

Study of Genetic Determinants in Alcoholic Hepatitis and Establishment of a Multicenter Prospective Cohort of Patients With Alcoholic Liver Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2019-10-23

Completion:

2027-04-30

Conditions

• Alcoholic Liver Disease
• Severe Alcoholic Hepatitis
• Alcoholic Cirrhosis

No Results Yet

NCT04100057 | ACTIVE_NOT_RECRUITING | NA

150 participants

Sleep Disturbance and Emotion Regulation Brain Dysfunction as Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Dementia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-08-31

Completion:

2026-04-30

Conditions

• Alzheimer Disease
• Mild Cognitive Impairment
• Neuropsychiatric Symptoms
• Sleep Disturbance

Interventions

• BEHAVIORAL

No Results Yet

NCT04054310 | RECRUITING | NA

225 participants

Non-Invasive Quantification of Liver Health in NASH (N-QUAN)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2020-08-05

Completion:

2026-06-01

Conditions

• NASH - Nonalcoholic Steatohepatitis

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04011566 | RECRUITING

50 participants

Assessment of ShuntCheck Performance Characteristics in Asymptomatic Patients With Normal Pressure Hydrocephalus

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2019-06-11

Completion:

2026-11-30

Conditions

• Hydrocephalus, Normal Pressure

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03978871 | COMPLETED | NA

163 participants

Effect of Emotion Mindsets on Emotion Processing

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2018-08-27

Completion:

2022-06-27

Conditions

• Emotions

Interventions

• BEHAVIORAL

Results Available

NCT03949855 | RECRUITING | PHASE2

58 participants

Belimumab With Rituximab for Primary Membranous Nephropathy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2020-03-06

Completion:

2029-03-01

Conditions

• Membranous Nephropathy
• Nephrotic Syndrome

Interventions

• DRUG

No Results Yet

NCT03862859 | RECRUITING | PHASE4

718 participants

The Danish Warfarin-Dialysis Study - Safety and Efficacy of Warfarin in Patients With Atrial Fibrillation on Dialysis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2019-10-09

Completion:

2027-01-31

Conditions

• Atrial Fibrillation and Flutter
• Stroke
• Major Bleed
• End-stage Renal Disease

Interventions

• DRUG

No Results Yet

NCT03855111 | COMPLETED | NA

161 participants

Symptom Management Efficacy Study to Reduce Distal Neuropathic Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2019-01-14

Completion:

2024-10-21

Conditions

• Neuropathic Pain
• HIV Neuropathy
• HIV/AIDS
• Pain

Interventions

• OTHER

Results Available

NCT03805932 | ACTIVE_NOT_RECRUITING | PHASE1

18 participants

Moxetumomab Pasudotox-tdfk (Lumoxiti(TM)) and Either Rituximab (Rituxan(R)) or Ruxience for Relapsed Hairy Cell Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2019-10-03

Completion:

2023-07-07

Conditions

• Hairy Cell Leukemia

Interventions

• DRUG
• BIOLOGICAL

Results Available

NCT03773822 | COMPLETED | PHASE3

380 participants

Low Dose of Hydrocortisone and Fludrocortisone in Adult Cardiogenic Shock.

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2019-04-19

Completion:

2023-04-05

Conditions

• Cardiogenic Shock

Interventions

• COMBINATION_PRODUCT
• OTHER

No Results Yet

NCT03752918 | WITHDRAWN | PHASE1

0 participants

The Effects of MDMA on Prefrontal and Amygdala Activation in PTSD.

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2024-05-31

Completion:

2028-01-31

Conditions

• Post Traumatic Stress Disorder

Interventions

• DRUG

No Results Yet

NCT03745326 | TERMINATED | PHASE1/PHASE2

5 participants

Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2019-05-16

Completion:

2022-08-23

Conditions

• Gastrointestinal Cancer
• Pancreatic Cancer
• Gastric Cancer
• Colon Cancer
• Rectal Cancer

Interventions

• DRUG
• BIOLOGICAL
• DIAGNOSTIC_TEST
• OTHER

Results Available

NCT03710772 | ACTIVE_NOT_RECRUITING | PHASE2

51 participants

Ibrutinib, Rituximab, Venetoclax, and Combination Chemotherapy in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2019-05-01

Completion:

2027-03-22

Conditions

• Mantle Cell Lymphoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT03702582 | COMPLETED | PHASE3

100 participants

Rivaroxaban vs. Warfarin for Post Cardiac Surgery Atrial Fibrillation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2019-04-30

Completion:

2023-10-01

Conditions

• Atrial Fibrillation
• Stroke
• Bleeding

Interventions

• DRUG

Results Available

NCT03643133 | ACTIVE_NOT_RECRUITING | PHASE2

60 participants

Mifamurtide Combined With Post-operative Chemotherapy for Newly Diagnosed High Risk Osteosarcoma Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2018-10-23

Completion:

2026-09-30

Conditions

• Osteosarcoma

Interventions

• DRUG
• COMBINATION_PRODUCT

No Results Yet

NCT03610022 | COMPLETED | PHASE4

27 participants

Relationship Between Pharmacokinetics and Safety of Vismodegib - OPTIVISMO-1

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2018-09-03

Completion:

2021-05-12

Conditions

• Metastatic Basal Cell Carcinoma
• Locally Advanced Basal Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT03606837 | COMPLETED | PHASE2

14 participants

68Ga-RM2 Compared to 68Ga-PSMA-617 PET/CT for Intermediate Risk Prostate Cancer Imaging

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2019-07-11

Completion:

2023-06-15

Conditions

• Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT03583580 | ACTIVE_NOT_RECRUITING | NA

537 participants

Accelerated Partial Breast Irradiation With IMRT in Early Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2018-07-19

Completion:

2030-07-31

Conditions

• Breast Neoplasms
• Neoplasm Recurrence, Local

Interventions

• RADIATION

No Results Yet

NCT03538912 | COMPLETED | NA

192 participants

Early Discontinuation of Empirical Antifungal Therapy and Biomarkers

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2018-06-06

Completion:

2024-09-03

Conditions

• Invasive Candidiasis

Interventions

• OTHER

No Results Yet

NCT03530397 | ACTIVE_NOT_RECRUITING | PHASE1

400 participants

A Study to Evaluate MEDI5752 in Subjects With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2018-04-24

Completion:

2025-07-14

Conditions

• Selected Advanced Solid Tumors

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT03499964 | ACTIVE_NOT_RECRUITING | NA

127 participants

ROBUST III- Re-Establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2018-06-22

Completion:

2020-12-10

Conditions

• Urethral Stricture

Interventions

• DEVICE

Results Available

NCT03396341 | RECRUITING

806 participants

Responses to Genetic Risk Modifier Testing Among Women With Pathogenic Variants in Breast Cancer Predisposition Genes

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2018-01-04

Completion:

2027-01-31

Conditions

• Genetic Testing
• BRCA1/2

Interventions

• OTHER
• BEHAVIORAL

No Results Yet

NCT03367741 | ACTIVE_NOT_RECRUITING | PHASE2

82 participants

Cabozantinib S-malate and Nivolumab in Treating Patients With Advanced, Recurrent, or Metastatic Endometrial Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2018-04-16

Completion:

2025-05-09

Conditions

• Advanced Endometrial Carcinoma
• Metastatic Endometrial Carcinoma
• Recurrent Endometrial Carcinoma
• Stage III Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
• Stage IV Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

Results Available

NCT03363256 | COMPLETED | NA

53 participants

Web-based Addiction Treatment: Cultural Adaptation With American Indians

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2018-05-30

Completion:

2020-06-30

Conditions

• Substance Use Disorders

Interventions

• BEHAVIORAL

Results Available

NCT03298477 | COMPLETED | NA

98 participants

EVAS2 IDE Prospective, Multicenter, Single Arm Safety and Effectiveness Confirmatory Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2017-12-01

Completion:

2022-06-07

Conditions

• Abdominal Aortic Aneurysm Without Rupture

Interventions

• DEVICE

Results Available

NCT03288428 | COMPLETED | PHASE4

80 participants

Analgesia Comparison of Nalbuphine and Morphine for Laparoscopic Myomectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2017-05-01

Completion:

2018-12-31

Conditions

• Postoperative Pain

Interventions

• DRUG

No Results Yet

NCT03263325 | ACTIVE_NOT_RECRUITING

305 participants

Evaluation of UDP-glucose as a Urinary Biomarker for Early Detection of Cardiac Surgery-associated Pediatric Acute Kidney Injury

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2017-10-25

Completion:

2023-06-28

Conditions

• Acute Kidney Injury

Interventions

• OTHER

No Results Yet

NCT03245346 | COMPLETED | NA

540 participants

Effects of Epidural Anesthesia and Analgesia on the Prognosis in Patients Undergoing Pancreatic Cancer Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2017-12-19

Completion:

2023-06-30

Conditions

• Cancer of Pancreas

Interventions

• DRUG

No Results Yet

NCT03242642 | RECRUITING | NA

1056 participants

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2017-10-23

Completion:

2027-05-30

Conditions

• Mitral Valve Regurgitation

Interventions

• DEVICE

No Results Yet

NCT03241056 | TERMINATED | NA

23 participants

Cognitive Checking Intervention for Maladaptive Beliefs About Memory

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2018-01-04

Completion:

2023-07-28

Conditions

• Obsessive-Compulsive Disorder

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT03226821 | TERMINATED | PHASE4

6 participants

Body Composition and Adipose Tissue in HIV

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2018-02-07

Completion:

2025-04-30

Conditions

• HIV Lipodystrophy Syndrome
• Growth Hormone Deficiency
• Body Composition

Interventions

• DRUG

Results Available

NCT03201094 | RECRUITING | NA

30 participants

Impact of NMES and HPRO on Recovery After SAH- Pilot Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2017-12-01

Completion:

2026-05-31

Conditions

• Subarachnoid Hemorrhage
• Muscle Atrophy
• Inflammation
• Nutritional and Metabolic Disease

Interventions

• DEVICE
• DIETARY_SUPPLEMENT

No Results Yet

NCT03180294 | COMPLETED | PHASE2

230 participants

Bupropion Hydrochloride in Improving Sexual Desire in Women With Breast or Gynecologic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2017-05-31

Completion:

2021-02-22

Conditions

• Breast Carcinoma
• Cervical Carcinoma
• Ovarian Carcinoma
• Postmenopausal
• Uterine Corpus Cancer
• Vaginal Carcinoma
• Vulvar Carcinoma

Interventions

• DRUG

Results Available

NCT03030378 | ACTIVE_NOT_RECRUITING | PHASE1

36 participants

Pembrolizumab and Recombinant Interleukin-12 in Treating Patients With Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2018-05-30

Completion:

2026-12-01

Conditions

• Metastatic Malignant Solid Neoplasm
• Unresectable Malignant Solid Neoplasm

Interventions

• PROCEDURE
• BIOLOGICAL

No Results Yet