Clinical Trials

NCT04975919 | ACTIVE_NOT_RECRUITING | PHASE2

20 participants

Venetoclax in Combination With Decitabine and Cedazuridine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-09-29

Completion:

2027-05-31

Conditions

• Recurrent Acute Biphenotypic Leukemia
• Recurrent Acute Myeloid Leukemia
• Refractory Acute Biphenotypic Leukemia
• Refractory Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT04963296 | ACTIVE_NOT_RECRUITING | PHASE3

303 participants

A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With Systemic Lupus Erythematosus

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-10-26

Completion:

2025-09-15

Conditions

• Systemic Lupus Erythematosus

Interventions

• DRUG

No Results Yet

NCT04963205 | COMPLETED | NA

24 participants

Sleeping Position Study in COPD Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2022-01-17

Completion:

2025-12-23

Conditions

• COPD
• Sleep

Interventions

• DEVICE
• OTHER

No Results Yet

NCT04960787 | ACTIVE_NOT_RECRUITING | NA

331 participants

Financial Navigation Program to Improve Understanding and Management of Financial Aspects of Cancer Care for Patients and Their Spouses

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-10-12

Completion:

2026-09-01

Conditions

• Hematopoietic and Lymphoid Cell Neoplasm
• Metastatic Malignant Solid Neoplasm
• Recurrent Malignant Solid Neoplasm

Interventions

• OTHER
• BEHAVIORAL

No Results Yet

NCT04953273 | RECRUITING | NA

756 participants

A Case Management Algorithm for Women Victims of Violence

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-07-06

Completion:

2026-07-31

Conditions

• Post-Traumatic Stress Disorder
• Violence-Related Symptom

Interventions

• OTHER

No Results Yet

NCT04936776 | COMPLETED

1034 participants

Pediatric Vaccinations

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-14

Start Date:

2021-02-09

Completion:

2023-12-21

Conditions

• Pediatric ALL
• Vaccination
• Immunization

Interventions

• BEHAVIORAL

No Results Yet

NCT04926818 | ACTIVE_NOT_RECRUITING | PHASE3

129 participants

Efficacy and Safety of Ofatumumab and Siponimod Compared to Fingolimod in Pediatric Patients With Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-10-05

Completion:

2026-03-25

Conditions

• Multiple Sclerosis (MS)

Interventions

• DRUG
• OTHER

No Results Yet

NCT04925154 | RECRUITING

192 participants

Tradeoffs in Patient Decision Making About Rectal Cancer Treatment: Benefits Compared to Quality Of Life.

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-14

Start Date:

2021-12-13

Completion:

2027-12-01

Conditions

• Patient Preference

Interventions

• BEHAVIORAL

No Results Yet

NCT04920799 | COMPLETED | NA

8 participants

Effect of Beet Juice Supplementation on Vascular and Inspiratory Muscle Function

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-11-12

Completion:

2025-08-28

Conditions

• Coronary Artery Disease

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04905797 | COMPLETED

316 participants

Aspects of Self-harm - Cognition, Imaging and Treatability

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-14

Start Date:

2021-04-30

Completion:

2025-12-31

Conditions

• Self-Harm, Deliberate
• Non-Suicidal Self Injury
• Attempt Suicide
• Personality Disorders

Interventions

• DIAGNOSTIC_TEST
• OTHER

No Results Yet

NCT04895696 | ACTIVE_NOT_RECRUITING | PHASE2

268 participants

A Study Evaluating the Efficacy and Safety of Afimetoran Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-10-11

Completion:

2026-06-18

Conditions

• Systemic Lupus Erythematosus

Interventions

• DRUG
• OTHER

No Results Yet

NCT04895592 | COMPLETED | EARLY_PHASE1

26 participants

Radiosurgery Before Surgery for the Treatment of Brain Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-07-20

Completion:

2023-09-09

Conditions

• Metastatic Malignant Neoplasm in the Brain
• Metastatic Malignant Solid Neoplasm

Interventions

• DRUG
• PROCEDURE
• RADIATION

No Results Yet

NCT04893863 | RECRUITING | PHASE1/PHASE2

20 participants

A Study of Plurogel® Compared to Standard Topical Dressing in Burn Injuries

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-10-01

Completion:

2028-12-31

Conditions

• Burns

Interventions

• DRUG

No Results Yet

NCT04865458 | TERMINATED | PHASE1

5 participants

A Study to Evaluate the Tolerability, Safety, Pharmacokinetics of HEC89736 in Patients With Relapsed or Refractory B-cell Hematologic Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-04-01

Completion:

2022-09-21

Conditions

• Relapsed or Refractory B-cell Hematologic Malignancies

Interventions

• DRUG

No Results Yet

NCT04862221 | RECRUITING | PHASE2

163 participants

TReatment for ImmUne Mediated PathopHysiology

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2022-02-09

Completion:

2026-08-31

Conditions

• Acute Liver Failure
• Fulminant Hepatic Failure
• Hepatic Encephalopathy
• Acute Liver Injury
• Immune Dysregulation

Interventions

• DRUG

No Results Yet

NCT04860375 | RECRUITING | NA

110 participants

Multidisciplinary Management of Severe COPD

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-09-22

Completion:

2028-12-31

Conditions

• Copd
• COPD Exacerbation

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT04858490 | COMPLETED | NA

30 participants

Remote Treatment of Alcohol Withdrawal

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-09-24

Completion:

2023-10-16

Conditions

• Alcohol Withdrawal

Interventions

• DRUG

Results Available

NCT04850222 | COMPLETED | PHASE2

55 participants

Fluoxetine Mitigation Mental Health Study for Patients With Musculoskeletal Trauma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-09-01

Completion:

2025-02-17

Conditions

• Musculoskeletal Injury

Interventions

• DRUG

Results Available

NCT04848116 | ACTIVE_NOT_RECRUITING | PHASE2

24 participants

Neoadjuvant Targeting of Myeloid Cell Populations in Combination With Nivolumab in Head & Neck Ca

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-04-24

Completion:

2027-04-30

Conditions

• Head and Neck Squamous Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT04840979 | ACTIVE_NOT_RECRUITING | PHASE2

107 participants

Discovery and Validation of Genetic Variants Affecting Microglial Activation in Alzheimer's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-05-11

Completion:

2026-12-31

Conditions

• Alzheimer Disease

Interventions

• DRUG

No Results Yet

NCT04821908 | COMPLETED

577 participants

Consequences of COVID 19 Pandemic on Childhood Asthma

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-14

Start Date:

2021-09-14

Completion:

2025-03-31

Conditions

• Asthma in Children

No Results Yet

NCT04801849 | COMPLETED | PHASE2

200 participants

Vitamin E Dosing Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2022-08-05

Completion:

2025-03-04

Conditions

• Nonalcoholic Fatty Liver Disease
• Nonalcoholic Steatohepatitis

Interventions

• DRUG

Results Available

NCT04789486 | RECRUITING | PHASE1/PHASE2

100 participants

Nano-SMART: Nanoparticles With MR Guided SBRT in Centrally Located Lung Tumors and Pancreatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-05-27

Completion:

2028-04-10

Conditions

• Non-small Cell Lung Cancer
• Advanced Pancreatic Adenocarcinoma
• Unresectable Pancreatic Cancer
• Ductal Adenocarcinoma of the Pancreas

Interventions

• DRUG
• RADIATION

No Results Yet

NCT04772911 | ACTIVE_NOT_RECRUITING

73 participants

Multicenter Phenotype-Genotype Analysis of Vascular Stains to Optimize Treatment Utilizing Optical Coherence Tomography

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-14

Start Date:

2021-03-11

Completion:

2025-04-01

Conditions

• Vascular Stains

Interventions

• DEVICE

No Results Yet

NCT04770896 | ACTIVE_NOT_RECRUITING | PHASE3

557 participants

A Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated With Atezolizumab and Bevacizumab

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-04-26

Completion:

2026-06-30

Conditions

• Unresectable Hepatocellular Carcinoma

Interventions

• DRUG

No Results Yet

NCT04769817 | ACTIVE_NOT_RECRUITING

500 participants

ProsTIC Registry of Men Treated With PSMA Theranostics

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-14

Start Date:

2021-05-19

Completion:

2026-07-31

Conditions

• Prostate Cancer
• Metastatic Castration-resistant Prostate Cancer

Interventions

• OTHER

No Results Yet

NCT04708418 | ACTIVE_NOT_RECRUITING | PHASE2

60 participants

A Study Evaluating Whether Pembrolizumab Alone or in Combination With CMP-001 Improves Efficacy of Treatment in Patients With Operable Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-10-15

Completion:

2026-12-31

Conditions

• Clinical Stage III Cutaneous Melanoma AJCC v8
• Melanoma of Unknown Primary
• Pathologic Stage IIIB Cutaneous Melanoma AJCC v8
• Pathologic Stage IIIC Cutaneous Melanoma AJCC v8
• Pathologic Stage IIID Cutaneous Melanoma AJCC v8
• Recurrent Cutaneous Melanoma

Interventions

• PROCEDURE
• BIOLOGICAL
• DRUG

No Results Yet

NCT04682392 | TERMINATED | NA

19 participants

ACL Bone Health and Loading Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-02-17

Completion:

2025-05-01

Conditions

• ACL Tear

Interventions

• DEVICE
• OTHER

No Results Yet

NCT04679467 | COMPLETED | NA

13 participants

Evaluation of PKU Sphere in Italy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2020-08-10

Completion:

2022-07-31

Conditions

• Phenylketonurias
• PKU

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04656925 | COMPLETED | NA

12 participants

Automated Reinforcement Management System (ARMS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-03-29

Completion:

2021-12-08

Conditions

• Alcohol Use Disorder

Interventions

• BEHAVIORAL

Results Available

NCT04641442 | ACTIVE_NOT_RECRUITING | PHASE2

17 participants

Study to Evaluate the Efficacy, Safety and Tolerability of MAS825 in Patients With Monogenic IL-18 Driven Autoinflammatory Diseases, Including NLRC4-GOF, XIAP Deficiency, or CDC42 Mutations

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2020-12-18

Completion:

2025-10-14

Conditions

• NLRC4-GOF, AIFEC (Autoinflammation With Infantile Enterocolitis), XIAP Deficiency, CDC42 Mutations

Interventions

• BIOLOGICAL

No Results Yet

NCT04630028 | COMPLETED | PHASE3

112 participants

A Study of Ustekinumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis (UC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-03-17

Completion:

2025-05-08

Conditions

• Colitis, Ulcerative

Interventions

• DRUG

No Results Yet

NCT04624763 | ACTIVE_NOT_RECRUITING | NA

683 participants

Protection of Cardiac Function With Left Bundle Branch Pacing in Patients With Atrioventricular Block

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-06-22

Completion:

2028-01-31

Conditions

• Atrioventricular Block

Interventions

• PROCEDURE

No Results Yet

NCT04619004 | ACTIVE_NOT_RECRUITING | PHASE2

277 participants

HERTHENA-Lung01: Patritumab Deruxtecan in Subjects With Metastatic or Locally Advanced EGFR-mutated Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-02-02

Completion:

2022-11-21

Conditions

• Non-Small Cell Lung Cancer Metastatic
• Non-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor Receptor

Interventions

• DRUG

Results Available

NCT04614909 | COMPLETED | EARLY_PHASE1

50 participants

Study of Pamiparib in Newly Diagnosed and rGBM

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-01-11

Completion:

2023-07-21

Conditions

• Glioblastoma Multiforme
• Glioblastoma
• Glioblastoma Multiforme, Adult

Interventions

• DRUG
• RADIATION

No Results Yet

NCT04598880 | COMPLETED | PHASE4

1180 participants

Comparison of 1 Liter PEG With Ascorbate and Sodium Picosulfate / Magnesium Citrate for High Quality Colon Cleansing

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2020-11-06

Completion:

2024-04-01

Conditions

• Colonic Diseases

Interventions

• DRUG

No Results Yet

NCT04593472 | COMPLETED | NA

273 participants

SHARE: Sharing Healthcare Wishes in Primary Care

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2020-10-21

Completion:

2023-10-24

Conditions

• Cognitive Impairment

Interventions

• BEHAVIORAL

Results Available

NCT04590235 | ACTIVE_NOT_RECRUITING | PHASE1

32 participants

A Study of Selumetinib in Chinese Paediatric and Adult Subjects With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2020-12-16

Completion:

2022-08-16

Conditions

• Neurofibromatosis 1
• Neurofibroma Plexiform

Interventions

• DRUG

No Results Yet

NCT04589234 | ACTIVE_NOT_RECRUITING | PHASE2

60 participants

Saltikva for Metastatic Pancreatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2020-10-20

Completion:

2030-12-31

Conditions

• Metastatic Pancreatic Cancer

Interventions

• DRUG

No Results Yet

NCT04576078 | RECRUITING | PHASE2

50 participants

Post-operative Analgesic Effect of Oral Nefopam

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-06-29

Completion:

2026-12-30

Conditions

• Postoperative Pain After a Total Knee Arthroplasty

Interventions

• DRUG

No Results Yet