Clinical Trials

NCT04572269 | COMPLETED

388 participants

Metabolomics of Obstructive Sleep Apnea

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-14

Start Date:

2020-09-29

Completion:

2025-09-12

Conditions

• Obstructive Sleep Apnea

Interventions

• OTHER

No Results Yet

NCT04559685 | TERMINATED | EARLY_PHASE1

10 participants

Study of Sonodynamic Therapy in Participants With Recurrent High-Grade Glioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-03-15

Completion:

2023-08-23

Conditions

• High Grade Glioma

Interventions

• COMBINATION_PRODUCT
• DEVICE

No Results Yet

NCT04532190 | RECRUITING | NA

30 participants

Finding Alternatives to Standard Treatment for Attention-Deficit Hyperactivity Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2026-03-01

Completion:

2027-12-31

Conditions

• Attention-Deficit/Hyperactivity Disorder (ADHD)

Interventions

• DEVICE

No Results Yet

NCT04523727 | SUSPENDED | PHASE3

45 participants

Study to Evaluate the Safety and Tolerability of Ferric Citrate in Children With Hyperphosphatemia Related to Chronic Kidney Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2022-06-16

Completion:

2026-12-31

Conditions

• Hyperphosphatemia Related to Chronic Kidney Disease

Interventions

• DRUG

No Results Yet

NCT04486378 | ACTIVE_NOT_RECRUITING | PHASE2

327 participants

A Phase II Clinical Trial Comparing the Efficacy of RO7198457 Versus Watchful Waiting in Patients With ctDNA-positive, Resected Stage II (High Risk) and Stage III Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-03-08

Completion:

2026-11-30

Conditions

• Colorectal Cancer Stage II
• Colorectal Cancer Stage III

Interventions

• DRUG
• OTHER

No Results Yet

NCT04477200 | ACTIVE_NOT_RECRUITING | PHASE1

68 participants

Mycophenolate Mofetil Combined With Radiation Therapy in Glioblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2020-08-05

Completion:

2025-01-06

Conditions

• Recurrent Glioblastoma
• Recurrent Gliosarcoma
• Recurrent Astrocytoma, Grade IV
• Newly Diagnosed Glioblastoma
• Newly Diagnosed Gliosarcoma
• Newly Diagnosed Astrocytoma, Grade IV

Interventions

• DRUG
• RADIATION
• PROCEDURE

Results Available

NCT04467502 | RECRUITING | NA

124 participants

Virtual Reality Exposure Therapy for Gambling Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2023-07-12

Completion:

2027-07-31

Conditions

• Gambling Disorder

Interventions

• OTHER

No Results Yet

NCT04462770 | RECRUITING | PHASE3

150 participants

A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2020-09-15

Completion:

2027-04-30

Conditions

• Dravet Syndrome

Interventions

• DRUG

No Results Yet

NCT04462406 | ACTIVE_NOT_RECRUITING | PHASE2

150 participants

Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-02-09

Completion:

2027-01-31

Conditions

• Advanced Melanoma
• Clinical Stage III Cutaneous Melanoma AJCC v8
• Clinical Stage IV Cutaneous Melanoma AJCC v8
• Melanoma of Unknown Primary
• Pathologic Stage IIIB Cutaneous Melanoma AJCC v8
• Pathologic Stage IIIC Cutaneous Melanoma AJCC v8
• Pathologic Stage IIID Cutaneous Melanoma AJCC v8
• Pathologic Stage IV Cutaneous Melanoma AJCC v8
• Unresectable Acral Lentiginous Melanoma
• Unresectable Melanoma
• Unresectable Mucosal Melanoma

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT04458610 | ACTIVE_NOT_RECRUITING | PHASE2

60 participants

Zanubrutinib and Rituximab for the Treatment of Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2020-05-26

Completion:

2027-05-26

Conditions

• Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04455841 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

84 participants

INCB000928 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Anemia Due to Myeloproliferative Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-03-19

Completion:

2025-04-01

Conditions

• Anemia
• Post-essential Thrombocythemia Myelofibrosis
• Post-polycythemia Vera Myelofibrosis

Interventions

• DRUG

Results Available

NCT04394546 | ACTIVE_NOT_RECRUITING | NA

3000 participants

CHAMPION-AF Clinical Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2020-10-15

Completion:

2027-12-31

Conditions

• Atrial Fibrillation
• Stroke
• Bleeding

Interventions

• DEVICE
• DRUG

No Results Yet

NCT04332276 | COMPLETED | PHASE1/PHASE2

12 participants

Dopaminergic restauratIon by intraVEntriculaire Administration

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2020-09-18

Completion:

2024-05-06

Conditions

• Parkinson Disease

Interventions

• DRUG

No Results Yet

NCT04327791 | COMPLETED | PHASE2/PHASE3

15 participants

COmbination Therapy With Baloxavir and Oseltamivir 1 for Hospitalized Patients With Influenza (The COMBO Trial 1)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2020-04-03

Completion:

2024-07-03

Conditions

• Influenza

Interventions

• DRUG

No Results Yet

NCT04295252 | RECRUITING

3000 participants

Altshock-2 REGISTRY

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-14

Start Date:

2020-07-01

Completion:

2030-12-31

Conditions

• Cardiogenic Shock

No Results Yet

NCT04246177 | COMPLETED | PHASE3

479 participants

Safety and Efficacy of Lenvatinib (E7080/MK-7902) With Pembrolizumab (MK-3475) in Combination With Transarterial Chemoembolization (TACE) in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma (MK-7902-012/E7080-G000-318/LEAP-012)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2020-05-22

Completion:

2025-08-19

Conditions

• Carcinoma, Hepatocellular

Interventions

• DRUG
• BIOLOGICAL
• PROCEDURE

No Results Yet

NCT04230395 | ACTIVE_NOT_RECRUITING | NA

450 participants

Alcohol Reduction Among People With TB and HIV in India

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2022-09-22

Completion:

2026-09-30

Conditions

• Tuberculosis
• HIV

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT04206371 | COMPLETED | NA

143 participants

Defibrillation Testing During Implantable Cardioverter Defibrillator (ICD) Replacement

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2020-02-03

Completion:

2022-01-19

Conditions

• Implantable Cardioverter-Defibrillators

Interventions

• DIAGNOSTIC_TEST

Results Available

NCT04204499 | ACTIVE_NOT_RECRUITING

526 participants

Analysis of Screen-detected Lung Cancers' Genomic Traits

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-14

Start Date:

2020-08-10

Completion:

2026-07-31

Conditions

• Lung Cancer

No Results Yet

NCT04195945 | ACTIVE_NOT_RECRUITING | PHASE2

60 participants

CPX-351 or CLAG-M Regimen for the Treatment of Acute Myeloid Leukemia or Other High-Grade Myeloid Neoplasms in Medically Less-Fit Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2020-05-27

Completion:

2025-06-06

Conditions

• Acute Myeloid Leukemia
• Myeloid Neoplasm

Interventions

• DRUG
• BIOLOGICAL
• OTHER

Results Available

NCT04195750 | ACTIVE_NOT_RECRUITING | PHASE3

755 participants

A Study of Belzutifan (MK-6482) Versus Everolimus in Participants With Advanced Renal Cell Carcinoma (MK-6482-005)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2020-02-27

Completion:

2024-04-15

Conditions

• Carcinoma, Renal Cell

Interventions

• DRUG

Results Available

NCT04187976 | COMPLETED

70 participants

Eosinophils Endotypes in Chronic Airway Inflammatory Diseases

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-14

Start Date:

2020-03-03

Completion:

2023-10-30

Conditions

• Eosinophilic Asthma
• Chronic Sinusitis
• Eosinophilic Rhinitis

No Results Yet

NCT04146688 | COMPLETED | NA

240 participants

Nonverbal Communication in Aged People

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2018-05-17

Completion:

2024-02-23

Conditions

• Alzheimer Disease

Interventions

• OTHER

No Results Yet

NCT04136002 | ACTIVE_NOT_RECRUITING

44467 participants

Evaluation of the ctDNA LUNAR Test in an Average Patient Screening Episode

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-14

Start Date:

2019-10-08

Completion:

2024-03-20

Conditions

• Colorectal Cancer

No Results Yet

NCT04122703 | COMPLETED | NA

79 participants

Trial of Tibial Nerve Stimulation for Treating Sexual Dysfunction

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2019-09-15

Completion:

2023-06-30

Conditions

• Female Sexual Dysfunction

Interventions

• DEVICE

Results Available

NCT04110522 | ACTIVE_NOT_RECRUITING | NA

18000 participants

Psoriatic Arthritis D2P Screening

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2019-07-22

Completion:

2027-12-31

Conditions

• Psoriatic Arthritis

Interventions

• OTHER

No Results Yet

NCT04101838 | ACTIVE_NOT_RECRUITING | PHASE4

50 participants

B Cell and Antibody Response to Seasonal Influenza Vaccines in Younger and Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-04-01

Completion:

2026-05-11

Conditions

• Influenza

Interventions

• DRUG

No Results Yet

NCT04098666 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

326 participants

Metformin in Alzheimer's Dementia Prevention

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2021-03-22

Completion:

2026-05-12

Conditions

• Mild Cognitive Impairment

Interventions

• DRUG

No Results Yet

NCT04068584 | COMPLETED | NA

1260 participants

Evaluation of the Impact of the SMART ANGEL ™ Device on Follow-up at Home Following Major or Intermediate Outpatient Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2020-02-03

Completion:

2024-10-21

Conditions

• Ambulatory Surgery

Interventions

• OTHER

No Results Yet

NCT04059172 | RECRUITING | EARLY_PHASE1

375 participants

Efficacy of Combined Ibuprofen and Acetaminophen Therapy Versus Ibuprofen Alone Versus Placebo Alone for Pain Management

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2019-12-10

Completion:

2028-06-01

Conditions

• Pain, Orofacial

Interventions

• DRUG

No Results Yet

NCT04057651 | COMPLETED

800 participants

Hip and Knee Scores

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-14

Start Date:

2018-08-28

Completion:

2020-05-19

Conditions

• Hip Osteoarthritis
• Knee Osteoarthritis

No Results Yet

NCT04042753 | ACTIVE_NOT_RECRUITING | PHASE2

9 participants

Nivolumab and Ipilimumab in People With Aggressive Pituitary Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2019-07-31

Completion:

2026-07-31

Conditions

• Pituitary
• Pituitary Tumor
• Pituitary Carcinoma
• Pituitary Cancer

Interventions

• DRUG

No Results Yet

NCT04030559 | TERMINATED | PHASE2

11 participants

Niraparib Before Surgery in Treating Patients With High Risk Localized Prostate Cancer and DNA Damage Response Defects

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2020-02-25

Completion:

2024-01-10

Conditions

• ATM Gene Mutation
• BRCA1 Gene Mutation
• BRCA2 Gene Mutation
• BRIP1 Gene Mutation
• CDK12 Gene Mutation
• CHEK1 Gene Mutation
• CHEK2 Gene Mutation
• DNA Damage Response Gene Mutation
• DNA Repair Gene Mutation
• FANCA Gene Mutation
• FANCD2 Gene Mutation
• FANCL Gene Mutation
• GEN1 Gene Mutation
• NBN Gene Mutation
• Prostate Carcinoma
• RAD51 Gene Mutation
• RAD51C Gene Mutation

Interventions

• DRUG
• PROCEDURE

Results Available

NCT04012138 | COMPLETED | PHASE4

419 participants

Insulin Dextrose Infusion vs Nebulized Salbutamol vs Combination of Salbutamol and Insulin Dextrose in Acute Hyperkalemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2019-12-20

Completion:

2025-12-20

Conditions

• Hyperkalemia

Interventions

• DRUG

No Results Yet

NCT04009148 | ACTIVE_NOT_RECRUITING

118 participants

Cascade Testing in Families With Newly Diagnosed Hereditary Breast and Ovarian Cancer Syndrome

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-14

Start Date:

2019-03-01

Completion:

2025-06-11

Conditions

• MSH2 A636P
• BRCA-Mutated Ovarian Carcinoma
• BRIP1 Gene Mutation
• MLH1 Gene Mutation
• MSH6 Gene Mutation
• PMS2 Gene Mutation
• EPCAM
• RAD51C Gene Mutation

Interventions

• OTHER

No Results Yet

NCT04003649 | ACTIVE_NOT_RECRUITING | PHASE1

20 participants

IL13Ra2-CAR T Cells With or Without Nivolumab and Ipilimumab in Treating Patients With GBM

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2019-12-02

Completion:

2024-12-18

Conditions

• Recurrent Glioblastoma
• Refractory Glioblastoma

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT04002245 | COMPLETED | NA

132 participants

A Pilot Study Efficiency of Techniques of 'Snail ' and 'Go-back' Application of an Alcoholic Antiseptic on Healthy Skin Before the Placement of a Intra-vascular Device,

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2019-04-08

Completion:

2019-06-19

Conditions

• Health Care Utilization

Interventions

• PROCEDURE

No Results Yet

NCT03953014 | RECRUITING

120 participants

Pharmacogenetics of Antidepressant-Induced Disinhibition

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-14

Start Date:

2019-01-02

Completion:

2026-09-30

Conditions

• Obsessive-Compulsive Disorder
• Anxiety Disorders
• Major Depressive Disorder
• Antidepressant Drug Adverse Reaction

No Results Yet

NCT03946696 | COMPLETED

20 participants

Animal-Assisted Therapy for People With Dementia

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-14

Start Date:

2022-01-15

Completion:

2022-12-31

Conditions

• Dementia

Interventions

• OTHER

No Results Yet

NCT03933384 | RECRUITING | PHASE4

140 participants

Tenofovir Alafenamide Versus Entecavir for the Treatment of Chronic Hepatitis B

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-14

Start Date:

2019-08-19

Completion:

2027-12-31

Conditions

• Hepatitis B
• Viral Hepatitis

Interventions

• DRUG

No Results Yet