Clinical Trials

NCT05218720 | COMPLETED

100 participants

Delirium and EuroSCORE II in Cardiac Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-08
Start Date:: 2022-03-01
Completion:: 2023-05-23

Conditions

Delirium

Interventions

OTHER

Results Available

NCT05212246 | NOT_YET_RECRUITING | PHASE3

1630 participants

Basal Cell Carcinoma Chemoprevention Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2026-08-03
Completion:: 2032-08-03

Conditions

Basal Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT05201781 | RECRUITING | PHASE4

295 participants

A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2022-03-09
Completion:: 2037-07-29

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05200442 | SUSPENDED | PHASE1/PHASE2

53 participants

A Study of VS-6766 and Cetuximab in Patients With Advanced Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2022-08-22
Completion:: 2027-05-01

Conditions

Colorectal Cancer
Colorectal Adenocarcinoma
Colorectal Cancer Metastatic
Advanced Colorectal Carcinoma
Advanced Colorectal Adenocarcinoma

Interventions

DRUG
OTHER

No Results Yet

NCT05199688 | RECRUITING | PHASE3

8 participants

A Study To Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, And Pharmacodynamics Of Satralizumab In Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2026-05-06
Completion:: 2027-03-31

Conditions

Neuromyelitis Optica Spectrum Disorder
NMOSD

Interventions

DRUG

No Results Yet

NCT05197049 | ACTIVE_NOT_RECRUITING | PHASE3

350 participants

A Study of Guselkumab Subcutaneous Therapy in Participants With Moderately to Severely Active Crohn's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2022-01-19
Completion:: 2023-07-04

Conditions

Crohn Disease

Interventions

DRUG

Results Available

NCT05192707 | COMPLETED

39 participants

Transcutaneous Oxygen Pressure (TcPO2) Determination.

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-08
Start Date:: 2022-03-01
Completion:: 2025-07-22

Conditions

Peripheral Arterial Diseases

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05184556 | ACTIVE_NOT_RECRUITING | NA

77 participants

Project HOME: Home-Based Treatment Options and Mechanisms for Eating Disorders

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2022-08-01
Completion:: 2026-03-30

Conditions

Anorexia Nervosa
Eating Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT05179876 | RECRUITING | PHASE3

280 participants

A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2022-05-04
Completion:: 2027-01-31

Conditions

Hypertension, Pulmonary

Interventions

DRUG

No Results Yet

NCT05178992 | COMPLETED | PHASE1/PHASE2

142 participants

Use of Socially Assistive Robots for Long Term Care Older Adults With Cognitive Impairment and Apathy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2023-02-07
Completion:: 2025-10-31

Conditions

Alzheimer Disease

Interventions

BEHAVIORAL

No Results Yet

NCT05170867 | COMPLETED | NA

49 participants

The Impact of Hafnia Alvei on Weight Loss and Glycaemic Control After Bariatric Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2022-01-14
Completion:: 2025-05-31

Conditions

Obesity
Type 2 Diabetes

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT05160584 | RECRUITING

300 participants

A Study of Real-Life Current Standards of Care in Participants With Relapsed and/or Refractory Multiple Myeloma

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-08
Start Date:: 2021-11-18
Completion:: 2028-04-30

Conditions

Relapsed/Refractory Multiple Myeloma

Interventions

OTHER

No Results Yet

NCT05143164 | COMPLETED | NA

60 participants

Hydrocolloid Dressing for Catheter Exit Site Care in Peritoneal Dialysis Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2022-03-11
Completion:: 2025-07-30

Conditions

Peritoneal Dialysis Catheter Exit Site Infection

Interventions

DEVICE
DRUG

No Results Yet

NCT05126472 | RECRUITING | PHASE1

55 participants

Study of 2141-V11 in People With Non-muscle Invasive Bladder Cancer That Did Not Respond to Standard Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2021-11-08
Completion:: 2027-11-30

Conditions

Non-muscle Invasive Bladder Cancer

Interventions

DRUG

No Results Yet

NCT05118204 | TERMINATED | PHASE4

23 participants

Randomized Trial of Buprenorphine Microdose Inductions During Hospitalization

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2022-09-29
Completion:: 2024-10-23

Conditions

Substance Use Disorders
Opioid-use Disorder
Chronic Pain

Interventions

DRUG
BEHAVIORAL

Results Available

NCT05114746 | COMPLETED | PHASE2

94 participants

Study of 177Lu-PSMA-617 In Metastatic Castrate-Resistant Prostate Cancer in Japan

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2022-01-25
Completion:: 2023-12-08

Conditions

Prostate Cancer

Interventions

RADIATION
OTHER

No Results Yet

NCT05100342 | RECRUITING

214 participants

Prospective Validation of a Points Score System Predicting 30-day Survival

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-08
Start Date:: 2022-09-12
Completion:: 2026-12-31

Conditions

Metastatic Cancer

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05092412 | ACTIVE_NOT_RECRUITING | PHASE2

30 participants

Low-dose Radiotherapy Combined With Durvalumab, Chemotherapy(EP) in the Treatment of ES-SCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2022-03-02
Completion:: 2023-02-06

Conditions

Lung Cancer
Extensive-stage Small-cell Lung Cancer
Durvalumab

Interventions

RADIATION
DRUG

No Results Yet

NCT05092269 | ACTIVE_NOT_RECRUITING | PHASE3

159 participants

A Long-term Extension Study of Ustekinumab in Pediatric Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2021-10-18
Completion:: 2027-09-29

Conditions

Crohn Disease
Colitis, Ulcerative
Arthritis, Psoriatic

Interventions

DRUG

No Results Yet

NCT05090384 | COMPLETED | PHASE2

50 participants

Pediatric GVHD Low Risk Steroid Taper Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2022-10-20
Completion:: 2025-03-27

Conditions

Acute Graft vs Host Disease
Allogeneic Bone Marrow Transplantation
Adverse Effects

Interventions

DRUG

Results Available

NCT05086250 | RECRUITING | EARLY_PHASE1

20 participants

Feasibility Study of Oral Ketamine Versus Placebo for the Treatment of Anxiety in Patients With Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2022-10-20
Completion:: 2026-07-15

Conditions

Anxiety
Pancreatic Cancer

Interventions

DRUG

No Results Yet

NCT05083169 | ACTIVE_NOT_RECRUITING | PHASE3

587 participants

A Study of Teclistamab in Combination With Daratumumab Subcutaneously (SC) (Tec-Dara) Versus Daratumumab SC, Pomalidomide, and Dexamethasone (DPd) or Daratumumab SC, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2021-10-14
Completion:: 2028-12-08

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05081128 | ACTIVE_NOT_RECRUITING | NA

100 participants

Efficacy in iNPH Shunting (PENS) Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2022-05-18
Completion:: 2027-05-31

Conditions

Idiopathic Normal Pressure Hydrocephalus (INPH)

Interventions

DEVICE

No Results Yet

NCT05078905 | RECRUITING

1200 participants

Vaccine Responses to SARS-CoV-2 and Other Emerging Infectious Diseases

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-08
Start Date:: 2021-10-13
Completion:: 2050-01-01

Conditions

COVID-19
Vaccination
Healthy Volunteer

No Results Yet

NCT05076617 | ENROLLING_BY_INVITATION | PHASE3

300 participants

A Study to Test the Safety and Tolerability of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2022-02-03
Completion:: 2028-11-30

Conditions

Stereotypical Prolonged Seizures

Interventions

DRUG

No Results Yet

NCT05075161 | RECRUITING | PHASE3

130 participants

Pirfenidone to Prevent Fibrosis in Ards.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2022-06-01
Completion:: 2026-06-30

Conditions

Acute Respiratory Distress Syndrome (ARDS)

Interventions

DRUG

No Results Yet

NCT05074940 | ACTIVE_NOT_RECRUITING | PHASE2

21 participants

Amivantamab in Adenoid Cystic Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2022-08-05
Completion:: 2026-03-02

Conditions

Salivary Gland Cancer

Interventions

DRUG

Results Available

NCT05064514 | ACTIVE_NOT_RECRUITING | NA

15 participants

Investigation of a Transcatheter Tricuspid Valved Stent Graft in Patients With Carcinoid Heart Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2022-04-06
Completion:: 2026-05-21

Conditions

Tricuspid Regurgitation
Tricuspid Valve Disease
Carcinoid Syndrome
Carcinoid Heart Disease

Interventions

DEVICE

No Results Yet

NCT05059041 | COMPLETED | PHASE2

42 participants

Dilated Versus Non-Dilated Wavefront Corrections for Patients With Down Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2022-05-06
Completion:: 2025-01-24

Conditions

Down Syndrome
Refractive Errors

Interventions

DEVICE

Results Available

NCT05050097 | ACTIVE_NOT_RECRUITING | PHASE1

166 participants

A Study of Talquetamab With Other Anticancer Therapies in Participants With Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2021-09-22
Completion:: 2025-03-31

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05049798 | ACTIVE_NOT_RECRUITING

1314 participants

A Study of Guselkumab and Interleukin-17 (IL-17) Inhibitor Therapies in Participants With Psoriatic Arthritis in Routine Clinical Practice

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-08
Start Date:: 2021-08-25
Completion:: 2027-08-01

Conditions

Arthritis, Psoriatic

Interventions

DRUG

No Results Yet

NCT05048680 | RECRUITING | NA

64 participants

Effect of Hypoxic Conditioning on Cerebrovascular Health in the Elderly

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2021-10-13
Completion:: 2024-03-17

Conditions

Hypoxia
Cerebral Hypoxia
Brain Diseases
Exercise
Aging
Cognitive Decline
Healthy Aging

Interventions

PROCEDURE

No Results Yet

NCT05041036 | AVAILABLE

Individual Patient Compassionate Use of Nirogacestat

Study Type:: EXPANDED_ACCESS
Last Updated:: 2026-05-08

Conditions

Desmoid Tumor
NOTCH Gene Mutation Positive Tumors

Interventions

DRUG

No Results Yet

NCT05028166 | AVAILABLE

Individual Patient Compassionate Use of Mirdametinib

Study Type:: EXPANDED_ACCESS
Last Updated:: 2026-05-08

Conditions

Neurofibromatosis Type 1-Associated Plexiform Neurofibromas
Histiocytic Neoplasm
Other MAP-K Pathway Driven Diseases

Interventions

DRUG

No Results Yet

NCT05027945 | RECRUITING | PHASE2

54 participants

A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2023-02-23
Completion:: 2026-07-01

Conditions

Immunodeficiency
Hematopoietic Stem Cell Transplantation

Interventions

DRUG
RADIATION
PROCEDURE

No Results Yet

NCT05006339 | ACTIVE_NOT_RECRUITING | NA

82 participants

The Use of Remote Monitoring for Orthodontic Retention Review

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2021-12-01
Completion:: 2026-05-01

Conditions

Orthodontic Relapse

Interventions

DEVICE
OTHER

No Results Yet

NCT04988295 | ACTIVE_NOT_RECRUITING | PHASE3

776 participants

A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2021-11-17
Completion:: 2023-07-10

Conditions

Carcinoma, Non-Small-Cell Lung

Interventions

DRUG

Results Available

NCT04987203 | COMPLETED | PHASE3

343 participants

Study to Compare Tivozanib in Combination With Nivolumab to Tivozanib Monotherapy in Subjects With Renal Cell Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2021-09-09
Completion:: 2026-01-20

Conditions

Renal Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT04986423 | RECRUITING | PHASE2

200 participants

ZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2021-09-08
Completion:: 2026-12-31

Conditions

Metastatic Castration-Resistant Prostate Cancer

Interventions

DRUG

No Results Yet

NCT04962412 | COMPLETED

3152 participants

Predicting Poor Outcomes of Cardiac Surgery-Associated Acute Kidney Injury Using Novel Biomarkers

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-08
Start Date:: 2021-07-15
Completion:: 2024-12-31

Conditions

Acute Kidney Injury
Critical Illness

Interventions

OTHER

No Results Yet