Clinical Trials Updated in 2025

NCT06506773 | COMPLETED

79 participants

Natural History Study of Exocrine Pancreatic Function in Infants With Cystic Fibrosis (CF)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-07-09
Completion:: 2025-11-27

Conditions

Cystic Fibrosis

No Results Yet

NCT06482463 | RECRUITING | NA

185 participants

Diagnostic of D-lactate in Cerebrospinal Fluid Level in Patients With Suspected Ventriculostomy-related Meningitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-02-12
Completion:: 2027-02-28

Conditions

Nosocomial Infection

Interventions

BIOLOGICAL

No Results Yet

NCT06477354 | COMPLETED | NA

64 participants

ACEMg Hearing Preservation, Tinnitus and Hyperacusis Relief

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-11-18
Completion:: 2025-12-23

Conditions

Sensorineural Hearing Loss
Tinnitus
SNHL
Inner Ear Hearing Loss

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06460961 | ACTIVE_NOT_RECRUITING | PHASE1

168 participants

A Study of MK-6837 as a Monotherapy and Combination Therapy in Participants With Advanced/Metastatic Solid Tumors (MK-6837-001)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-07-14
Completion:: 2027-07-13

Conditions

Neoplasm Metastasis

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06452732 | RECRUITING

283 participants

Using Multiparametric Flow Cytometry to Detect Peripheral Blood and Bone Marrow Leukaemia Stem Cells for Relapse Prediction in P-AML

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-11-01
Completion:: 2026-06-30

Conditions

Acute Myeloid Leukemia
Acute Lymphoblastic Leukemia

Interventions

OTHER

No Results Yet

NCT06411158 | RECRUITING | NA

216 participants

Training for Urinary Leakage Improvement After Pregnancy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-11-12
Completion:: 2027-05-12

Conditions

Urinary Incontinence
Delivery Complication

Interventions

OTHER
DEVICE

No Results Yet

NCT06392464 | COMPLETED

106 participants

Validation of Naevia Medical in Valvulopathies

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-03-27
Completion:: 2025-01-24

Conditions

Heart Valve Disease

Interventions

DEVICE

Results Available

NCT06366789 | RECRUITING | PHASE1

150 participants

Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated or Spliceosome Mutated Relapsed or Refractory Acute Myeloid Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-05-29
Completion:: 2026-01-31

Conditions

AML With Gene Mutations

Interventions

DRUG

No Results Yet

NCT06362005 | COMPLETED | PHASE4

50 participants

The Efficacy of Selenium as an Alternative or Complementary Topical Treatment of Oral Lichen Planus

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-05-01
Completion:: 2025-07-01

Conditions

Lichen Planus, Oral

Interventions

DRUG

No Results Yet

NCT06359808 | RECRUITING

152 participants

Clinical Characteristics of Sleep Disorders in Patients With Ulcerative Colitis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-04-01
Completion:: 2026-06-30

Conditions

Colitis, Ulcerative
Sleep Quality
Gastrointestinal Microbiome
Autonomic Nervous System Imbalance

No Results Yet

NCT06354673 | COMPLETED | NA

205 participants

Stellate Ganglion Block Combined With Dexmedetomidine or Subanesthetic Ketamine Infusion for Treatment of Neurostorm.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-04-04
Completion:: 2025-09-04

Conditions

Paroxysmal Sympathetic Hyperactivity

Interventions

DRUG
PROCEDURE

No Results Yet

NCT06350006 | RECRUITING | PHASE1

924 participants

SHR-A1904 Combinations in CLDN18.2-Positive Advanced Solid Tumor

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-05-29
Completion:: 2027-12-30

Conditions

CLDN18.2-positive Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT06295432 | RECRUITING | PHASE2

90 participants

A Phase II Clinical Trial of DZD9008 in Combination With AZD4205 in Standard Treatment Failed NSCLC Patients With EGFR Mutations (WU-KONG21)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-06-01
Completion:: 2026-12-31

Conditions

Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT06294678 | ACTIVE_NOT_RECRUITING | PHASE3

198 participants

Effect of Stem Cell Infusion Time on aGVHD in Patients With Hematological Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-03-01
Completion:: 2025-09-30

Conditions

Acute Graft-versus-host Disease

Interventions

PROCEDURE

No Results Yet

NCT06261528 | ENROLLING_BY_INVITATION | PHASE1

20 participants

Study of Circadian Focused Light Therapy in Progressive Multiple Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-04-18
Completion:: 2026-07-01

Conditions

Progressive Multiple Sclerosis

Interventions

DEVICE

No Results Yet

NCT06260800 | COMPLETED

76 participants

Spanish Version of Credibility and Expectancy Questionnaire in Patients With Musculoskeletal Injuries

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-01-08
Completion:: 2024-07-15

Conditions

Validation Study

Interventions

OTHER

No Results Yet

NCT06219616 | COMPLETED | NA

80 participants

Prediction of BK Virus Reactivation in Kidney Transplant Recipient

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-05-01
Completion:: 2025-03-30

Conditions

Kidney Transplant Infection
BK Virus Infection
BK Virus Nephropathy

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06210633 | RECRUITING

1000 participants

Prospective Registry of Endovascular Thrombectomy for eXtra-Large Ischemic Stroke

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-01-20
Completion:: 2025-12-31

Conditions

Acute Ischemic Stroke (AIS)
Acute Ischemic Stroke From Large Vessel Occlusion

Interventions

OTHER

No Results Yet

NCT06185673 | RECRUITING | PHASE1/PHASE2

30 participants

A Study to Evaluate the Safety and Clinical Activity of Intramuscular Doses of BB-301 Administered to Subjects With Oculopharyngeal Muscular Dystrophy With Dysphagia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-11-28
Completion:: 2030-11-30

Conditions

Oculopharyngeal Muscular Dystrophy

Interventions

GENETIC

No Results Yet

NCT06168071 | ENROLLING_BY_INVITATION | NA

10 participants

Transauricular Vagus Nerve Stimulation in Children

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-11-15
Completion:: 2026-05-31

Conditions

Hypoxia-Ischemia, Brain

Interventions

DEVICE

No Results Yet

NCT06161376 | RECRUITING

400 participants

Role of Urinary Sphingosine 1-Phosphate as a Biomarker for Detrusor Hyperactivity in Multiple Sclerosis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-12-04
Completion:: 2027-12-31

Conditions

Multiple Sclerosis

Interventions

OTHER

No Results Yet

NCT06161363 | COMPLETED

102 participants

Description of Compliance With Hydroxychloroquine Treatment in Patients With Systemic Lupus Erythematosus

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-11-27
Completion:: 2024-11-16

Conditions

Lupus Erythematosus

Interventions

OTHER

No Results Yet

NCT06137625 | RECRUITING | NA

68 participants

Rhythm Effect on Dance Learning in Typical Development Children and Children With Motor Disorders.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-07-02
Completion:: 2027-01-31

Conditions

Cerebral Palsy (CP)

Interventions

BEHAVIORAL

No Results Yet

NCT06137326 | COMPLETED | NA

60 participants

PEMF vs Laser for Stress Urinary Incontinence

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-11-17
Completion:: 2025-01-21

Conditions

Stress Urinary Incontinence

Interventions

DEVICE

No Results Yet

NCT06132516 | ACTIVE_NOT_RECRUITING | NA

50 participants

Effects of HIIT on HRV in Sub-acute Post-stroke Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-03-15
Completion:: 2027-09-30

Conditions

Stroke

Interventions

OTHER

No Results Yet

NCT06127264 | RECRUITING | NA

60 participants

Reliability of Force Measurement Within the Carbon Fiber Orthosis Proximal Cuff

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-03-01
Completion:: 2026-12-31

Conditions

Healthy
Ankle Foot Orthosis (AFO)
Peripheral Neuropathy

Interventions

DEVICE

No Results Yet

NCT06084338 | RECRUITING | PHASE2

60 participants

Randomized Phase II Trial of Targeted Radiation With no Castration for Mcrpc

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-12-14
Completion:: 2027-11-29

Conditions

Prostate Cancer

Interventions

RADIATION
DRUG

No Results Yet

NCT06072196 | COMPLETED

3017 participants

A Study to Learn About Novel Hormonal Therapies in People With Metastatic Castration-Sensitive Prostate Cancer (mCSPC)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-10-04
Completion:: 2024-12-18

Conditions

Prostatic Neoplasms

Interventions

DRUG

Results Available

NCT06048328 | NOT_YET_RECRUITING | PHASE1/PHASE2

192 participants

Game Changers for Family Planning Peer Advocacy Program

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2027-11-15
Completion:: 2030-11-01

Conditions

Family Planning

Interventions

BEHAVIORAL

No Results Yet

NCT06029712 | COMPLETED | PHASE2

35 participants

Heart Failure Polypill at a Safety Net Hospital

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-02-27
Completion:: 2024-09-17

Conditions

Heart Failure With Reduced Ejection Fraction
HIV Infections

Interventions

DRUG

Results Available

NCT06018961 | RECRUITING

161 participants

Study of Postoperative Ileus in Digestive Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-04-24
Completion:: 2026-06-15

Conditions

Colorectal Surgery

Interventions

OTHER

No Results Yet

NCT06016764 | COMPLETED | PHASE1

26 participants

Use of MRI and cTBS for Catatonia in Autism

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-08-23
Completion:: 2025-12-01

Conditions

Autism Spectrum Disorder
Catatonia
Intellectual Disability

Interventions

DEVICE

No Results Yet

NCT05981183 | RECRUITING | NA

20 participants

Transcutaneous Auricular Vagus Nerve Stimulation Device in CKD Population

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-08-09
Completion:: 2026-01-07

Conditions

Chronic Kidney Disease

Interventions

DEVICE

No Results Yet

NCT05980130 | COMPLETED | NA

9 participants

Can Rumination-Focused Cognitive Behavioral Therapy Reduce the Risk of Cardio-vascular Disease?

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-08-15
Completion:: 2025-09-12

Conditions

Rumination
Depressive Symptoms
Blood Pressure

Interventions

BEHAVIORAL

No Results Yet

NCT05962541 | RECRUITING | PHASE4

327 participants

Vesical Imaging-Reporting and Data System (VI-RADS) Followed by Photodynamic Trans-urethral Resection of Bladder Tumours (PDD-TURBT) to Avoid Secondary Resections (Re-TURBT) in Non-Muscle Invasive Bladder Cancers (NMIBCs)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-22
Completion:: 2028-12-31

Conditions

Non-muscle-invasive Bladder Cancer
Non-Muscle Invasive Bladder Urothelial Carcinoma
High Risk Non-Muscle Invasive Bladder Urothelial Carcinoma

Interventions

DRUG
DEVICE

No Results Yet

NCT05960682 | COMPLETED

14 participants

French Translation and Validation of the Brief Index of Sexual Functioning for Men

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-07-15
Completion:: 2024-07-15

Conditions

Sexual Dysfunction Male

Interventions

OTHER

No Results Yet

NCT05956418 | RECRUITING | PHASE4

400 participants

A Study to Assess the Safety and Efficacy of Centhaquine in Hypovolemic Shock Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2021-08-13
Completion:: 2026-06-30

Conditions

Hypovolemic Shock

Interventions

DRUG

No Results Yet

NCT05955326 | RECRUITING | PHASE4

160 participants

Study to Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-01-08
Completion:: 2026-02-28

Conditions

Acute Cerebral Ischemia

Interventions

DRUG
OTHER

No Results Yet

NCT05949983 | RECRUITING | NA

866 participants

Health Economic Evaluation of an Adapted Physical Activity Program for Women With Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-12-23
Completion:: 2027-12-31

Conditions

Breast Neoplasm

Interventions

OTHER

No Results Yet

NCT05914558 | WITHDRAWN

0 participants

Comorbid Painful TMD Among Trigeminal Neuralgia

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2022-08-01
Completion:: 2026-08-30

Conditions

Trigeminal Neuralgia
Temporomandibular Disorder
Myofascial Pain
Trigeminal Neuropathy

Interventions

DIAGNOSTIC_TEST

No Results Yet