Clinical Trials Updated in 2025

NCT06726876 | RECRUITING | PHASE3

150 participants

Therapeutic Effect of Manuka Honey Oral Rinse in Periodontitis Patients Undergoing Hemodialysis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-10-01
Completion:: 2025-12-30

Conditions

Periodontitis
Hemodialysis

Interventions

DIETARY_SUPPLEMENT
DRUG

No Results Yet

NCT06715839 | RECRUITING | NA

400 participants

Target-specific immunoPET Imaging of Digestive System Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-12-04
Completion:: 2027-09-30

Conditions

Malignancy
Digestive Cancer
Digestive System Neoplasm
Digestive System Carcinoma
Digestive System Cancer
Liver Cancer
Stomach Cancer
Colon Cancer
Rectum Cancer
Pancreatic Cancer
Esophagus Cancer
Gallbladder Carcinoma
Small Intestine Cancer
Appendix Cancer
Bile Duct Carcinoma

Interventions

DRUG

No Results Yet

NCT06715397 | ENROLLING_BY_INVITATION

150 participants

Cross-Cultural Adaptation, Validity and Reliability of the Turkish Version of the Adolfsson-Björnsson Upper Extremity Activity Scale (ABAS)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-29
Completion:: 2026-10-30

Conditions

Upper Extremity Injuries
Questionnaire and Survey
Reliability and Validity

Interventions

OTHER

No Results Yet

NCT06714591 | RECRUITING | PHASE1

120 participants

Evaluate the Safety, Tolerability, Pharmacokinetic Profile, Efficacy of Bl-M11D1

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-12-19
Completion:: 2026-12-31

Conditions

Relapsed/Refractory Acute Myeloid Leukemia

Interventions

DRUG

No Results Yet

NCT06713434 | ACTIVE_NOT_RECRUITING | PHASE1

20 participants

Pilot Study of ELK-003 Eye Drops for Treating Ocular Manifestations of Epidermolysis Bullosa

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-05-07
Completion:: 2026-06-30

Conditions

Junctional Epidermolysis Bullosa
Epidermolysis Bullosa (EB)
Dystrophic Epidermolysis Bullosa
Recessive Dystrophic Epidermolysis Bullosa

Interventions

BIOLOGICAL

No Results Yet

NCT06710119 | RECRUITING | NA

60 participants

Effect of Custom Dynamic Orthoses on Forefoot Loading

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-06-18
Completion:: 2027-12-31

Conditions

Lower Extremity Injuries

Interventions

OTHER

No Results Yet

NCT06706505 | COMPLETED | NA

44 participants

Mindfulness-Based Art Therapy for Nurses: Difficulties in Emotion Regulation, Burnout, and Psychological Flexibility

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-12-01
Completion:: 2024-12-05

Conditions

Mental Health Wellness 1
Burnout, Professional

Interventions

BEHAVIORAL

No Results Yet

NCT06699030 | RECRUITING | NA

100 participants

A Strategy for Gallstone Expulsion Through Dietary Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-12-24
Completion:: 2026-12-01

Conditions

Gallbladder Stone

Interventions

DRUG
OTHER

No Results Yet

NCT06697405 | COMPLETED

1444 participants

Impact of Cardiopulmonary Bypass Time on Gastrointestinal Complications

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-12-24
Completion:: 2025-12-25

Conditions

Valvular Disease

Interventions

OTHER

No Results Yet

NCT06685406 | COMPLETED

120 participants

The Validity of Thorathic Fluid Content as Non Invasive Predictor on Weaning of Mechanical Ventilation in Critically Ill Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-11-18
Completion:: 2025-11-18

Conditions

Cardiometry
Thorathic Fluid Content
Weaning From Mechanical Ventilation

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06680089 | RECRUITING | PHASE2

300 participants

CD70-targeted immunoPET Imaging of Kidney Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-11-27
Completion:: 2026-11-30

Conditions

Urologic Neoplasms
Urogenital Neoplasms
Kidney Neoplasms
Neoplasms

Interventions

DRUG

No Results Yet

NCT06649682 | SUSPENDED | PHASE1

20 participants

68Ga-NYM096/177Lu-NYM096 in Metastatic ccRCC

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-11-21
Completion:: 2026-10-31

Conditions

Clear Cell Renal Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT06600802 | RECRUITING | NA

120 participants

Intrinsic Validity of Molecular Marker(s) Detection on Tissular Tumoral DNA to Predict the Efficacy of 177Lutetium-PSMA-617 (Lu-PSMA) Treatment for Castration-resistant Metastatic Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-10-08
Completion:: 2034-06-30

Conditions

Castration-resistant Metastatic Prostate Cancer
Treated by 177Lutetium-PSMA-617 (Lu-PSMA)

Interventions

BIOLOGICAL

No Results Yet

NCT06597747 | COMPLETED | NA

20 participants

Design Improvements With SONNET 3

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-12-16
Completion:: 2025-05-22

Conditions

Hearing Loss, Sensorineural

Interventions

DEVICE

Results Available

NCT06576024 | COMPLETED | PHASE4

392 participants

Immunogenicity and Safety of Inactivated Hepatitis A Vaccine in HIV-infected People

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-12-19
Completion:: 2025-04-25

Conditions

Hepatitis A
Immunodeficiency
HIV Infections

Interventions

BIOLOGICAL

No Results Yet

NCT06568718 | COMPLETED | NA

229 participants

Efficacy and Safety of Longidaze in the Treatment of Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-03-20
Completion:: 2024-02-09

Conditions

Lower Urinary Tract Symptoms
Prostatic Hyperplasia

Interventions

DRUG

No Results Yet

NCT06568094 | RECRUITING | PHASE1/PHASE2

100 participants

A Study of HRS-5041 Tablets Combined With Antitumor Therapy in Subjects With Advanced Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-09-25
Completion:: 2026-06-30

Conditions

Prostate Cancer

Interventions

DRUG

No Results Yet

NCT06567041 | COMPLETED | PHASE1

82 participants

A Research Study of How Safe a New Medicine Called NNC0519 0130 is and to Test Its Effect in People Living With Excess Body Weight With or Without Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-08-07
Completion:: 2025-12-10

Conditions

Diabetes Mellitus, Type 2
Obesity

Interventions

DRUG

No Results Yet

NCT06531499 | RECRUITING | PHASE1

106 participants

A Study of Radiation Dosimetry, Safety, and Tolerability of Extended Lutetium (177Lu) Vipivotide Tetraxetan Treatment in Chemo-naïve Adults With Metastatic Castration-resistant Prostate Cancer: RADIOpharmaceutical DOSimetry Evaluation (RADIODOSE) Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-11-11
Completion:: 2028-11-24

Conditions

Metastatic Castration-Resistant Prostate Cancer

Interventions

DRUG

No Results Yet

NCT06524427 | RECRUITING | NA

1124 participants

Robot-Assisted vs. Video-Assisted Lobectomy for NSCLC (RAVAR)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2020-08-25
Completion:: 2030-12-31

Conditions

Non Small Cell Lung Cancer

Interventions

PROCEDURE

No Results Yet

NCT06512558 | RECRUITING | NA

20 participants

Augmented Reality Feasibility for Non-invasive Preoperative Tracking in Breast Cancer Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-11-14
Completion:: 2027-11-01

Conditions

Subclinical Breast Cancer Lesion

Interventions

PROCEDURE

No Results Yet

NCT06506773 | COMPLETED

79 participants

Natural History Study of Exocrine Pancreatic Function in Infants With Cystic Fibrosis (CF)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-07-09
Completion:: 2025-11-27

Conditions

Cystic Fibrosis

No Results Yet

NCT06482463 | RECRUITING | NA

185 participants

Diagnostic of D-lactate in Cerebrospinal Fluid Level in Patients With Suspected Ventriculostomy-related Meningitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-02-12
Completion:: 2027-02-28

Conditions

Nosocomial Infection

Interventions

BIOLOGICAL

No Results Yet

NCT06477354 | COMPLETED | NA

64 participants

ACEMg Hearing Preservation, Tinnitus and Hyperacusis Relief

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-11-18
Completion:: 2025-12-23

Conditions

Sensorineural Hearing Loss
Tinnitus
SNHL
Inner Ear Hearing Loss

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06460961 | ACTIVE_NOT_RECRUITING | PHASE1

168 participants

A Study of MK-6837 as a Monotherapy and Combination Therapy in Participants With Advanced/Metastatic Solid Tumors (MK-6837-001)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-07-14
Completion:: 2027-07-13

Conditions

Neoplasm Metastasis

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06452732 | RECRUITING

283 participants

Using Multiparametric Flow Cytometry to Detect Peripheral Blood and Bone Marrow Leukaemia Stem Cells for Relapse Prediction in P-AML

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-11-01
Completion:: 2026-06-30

Conditions

Acute Myeloid Leukemia
Acute Lymphoblastic Leukemia

Interventions

OTHER

No Results Yet

NCT06415773 | COMPLETED | PHASE3

367 participants

Effects of Berberine Ursodeoxycholate (HTD1801) Versus Dapagliflozin in Patients With Type 2 Diabetes Inadequately Controlled With Metformin

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-06-04
Completion:: 2025-06-13

Conditions

T2DM (Type 2 Diabetes Mellitus)

Interventions

DRUG

No Results Yet

NCT06411158 | RECRUITING | NA

216 participants

Training for Urinary Leakage Improvement After Pregnancy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-11-12
Completion:: 2027-05-12

Conditions

Urinary Incontinence
Delivery Complication

Interventions

OTHER
DEVICE

No Results Yet

NCT06392464 | COMPLETED

106 participants

Validation of Naevia Medical in Valvulopathies

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-03-27
Completion:: 2025-01-24

Conditions

Heart Valve Disease

Interventions

DEVICE

Results Available

NCT06366789 | RECRUITING | PHASE1

150 participants

Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated or Spliceosome Mutated Relapsed or Refractory Acute Myeloid Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-05-29
Completion:: 2026-01-31

Conditions

AML With Gene Mutations

Interventions

DRUG

No Results Yet

NCT06362005 | COMPLETED | PHASE4

50 participants

The Efficacy of Selenium as an Alternative or Complementary Topical Treatment of Oral Lichen Planus

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-05-01
Completion:: 2025-07-01

Conditions

Lichen Planus, Oral

Interventions

DRUG

No Results Yet

NCT06359808 | RECRUITING

152 participants

Clinical Characteristics of Sleep Disorders in Patients With Ulcerative Colitis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-04-01
Completion:: 2026-06-30

Conditions

Colitis, Ulcerative
Sleep Quality
Gastrointestinal Microbiome
Autonomic Nervous System Imbalance

No Results Yet

NCT06354673 | COMPLETED | NA

205 participants

Stellate Ganglion Block Combined With Dexmedetomidine or Subanesthetic Ketamine Infusion for Treatment of Neurostorm.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-04-04
Completion:: 2025-09-04

Conditions

Paroxysmal Sympathetic Hyperactivity

Interventions

DRUG
PROCEDURE

No Results Yet

NCT06350006 | RECRUITING | PHASE1

924 participants

SHR-A1904 Combinations in CLDN18.2-Positive Advanced Solid Tumor

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-05-29
Completion:: 2027-12-30

Conditions

CLDN18.2-positive Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT06326047 | COMPLETED | PHASE2

299 participants

A Research Study Comparing How Well Different Doses of the Medicine NN0519-0130 Lower Blood Sugar in People With Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-03-18
Completion:: 2025-09-19

Conditions

Diabetes Mellitus, Type 2

Interventions

DRUG

No Results Yet

NCT06295432 | RECRUITING | PHASE2

90 participants

A Phase II Clinical Trial of DZD9008 in Combination With AZD4205 in Standard Treatment Failed NSCLC Patients With EGFR Mutations (WU-KONG21)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-06-01
Completion:: 2026-12-31

Conditions

Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT06294678 | ACTIVE_NOT_RECRUITING | PHASE3

198 participants

Effect of Stem Cell Infusion Time on aGVHD in Patients With Hematological Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-03-01
Completion:: 2025-09-30

Conditions

Acute Graft-versus-host Disease

Interventions

PROCEDURE

No Results Yet

NCT06261528 | ENROLLING_BY_INVITATION | PHASE1

20 participants

Study of Circadian Focused Light Therapy in Progressive Multiple Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-04-18
Completion:: 2026-07-01

Conditions

Progressive Multiple Sclerosis

Interventions

DEVICE

No Results Yet

NCT06260800 | COMPLETED

76 participants

Spanish Version of Credibility and Expectancy Questionnaire in Patients With Musculoskeletal Injuries

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-01-08
Completion:: 2024-07-15

Conditions

Validation Study

Interventions

OTHER

No Results Yet

NCT06219616 | COMPLETED | NA

80 participants

Prediction of BK Virus Reactivation in Kidney Transplant Recipient

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-05-01
Completion:: 2025-03-30

Conditions

Kidney Transplant Infection
BK Virus Infection
BK Virus Nephropathy

Interventions

DIAGNOSTIC_TEST

No Results Yet