Clinical Trials Updated in 2025

NCT06998069 | RECRUITING | PHASE3

20 participants

Head and Neck Cancer Study Project in the Geriatric Population

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-08-27
Completion:: 2026-06-01

Conditions

Head and Neck Neoplasms

Interventions

DRUG

No Results Yet

NCT06994975 | RECRUITING | PHASE3

890 participants

CHinese ischEmic Stroke Beyond 4.5 Hours With TeNecteplase Under Optimized Non-Contrast CT Selection

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-11-03
Completion:: 2028-03-31

Conditions

Acute Ischemic Stroke

Interventions

DRUG

No Results Yet

NCT06984783 | COMPLETED | NA

25 participants

Visual Health Evaluation of New Designed Blue-blocking Glasses

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-04-18
Completion:: 2025-06-20

Conditions

Blue-blocking Glasses

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06974929 | RECRUITING | PHASE1/PHASE2

80 participants

A Clinical Study of HRS-6209 Combined With Other Treatment Regimens in Patients With Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-05-22
Completion:: 2025-12-31

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet

NCT06974266 | RECRUITING | NA

60 participants

An Efficacy and Safety Study of Akkermansia Muciniphila AKM Lab-01 in Hypercholesterolaemia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-06-25
Completion:: 2026-07-30

Conditions

Hypercholesterolaemia

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06960525 | COMPLETED | NA

26 participants

Joint Mobilization vs. Strengthening Exercises on Cervical Proprioception for Nonspecific Neck Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2024-10-20
Completion:: 2025-02-18

Conditions

Chronic Neck Pain
Nonspecific Neck Pain

Interventions

OTHER

No Results Yet

NCT06956820 | RECRUITING | NA

120 participants

Empowering Patients to Improve Safety in Polymedication

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-07-27
Completion:: 2026-03-31

Conditions

Polypharmacy

Interventions

DEVICE

No Results Yet

NCT06952608 | RECRUITING | PHASE4

140 participants

Effect of Ciprofol on Intraoperative Hypotension in Elderly Patients Receiving Renin-angiotensin System Inhibitors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-04-10
Completion:: 2026-02-10

Conditions

Intraoperative Hypotension
Ciprofol
Renin-angiotensin System Inhibitors

Interventions

DRUG

No Results Yet

NCT06943222 | COMPLETED | NA

104 participants

Comparative Effects of Traditional Play and Free Play in Primary School Children

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-04-17
Completion:: 2025-09-17

Conditions

Children

Interventions

OTHER

No Results Yet

NCT06943196 | COMPLETED | NA

22 participants

Effects of Structured Physical Activity Breaks and Free Play in Children With Mild Intellectual Disability

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-04-17
Completion:: 2025-09-17

Conditions

Intellectual Disability, Mild

Interventions

OTHER

No Results Yet

NCT06934759 | ENROLLING_BY_INVITATION

30 participants

Impact and Lived Experience of Parents of a Child With a Large or Giant Congenital Melanocytic Nevus

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-12-01
Completion:: 2026-06-30

Conditions

Congenital Melanocytic Nevi
Congenital Melanocytic Nevus
Parent
Psychology, Social

Interventions

OTHER

No Results Yet

NCT06916273 | COMPLETED | PHASE1

40 participants

Safety, Tolerability, and Pharmacokinetics of PA9159 Inhalation Aerosol in Healthy Adult Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2024-07-22
Completion:: 2024-09-12

Conditions

Bronchial Asthma

Interventions

DRUG

No Results Yet

NCT06913621 | NOT_YET_RECRUITING

138 participants

The Use of High Bile-Binding Foods to Reduce Upper Gastrointestinal Bile Acid Concentrations (Aim 3)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2026-07-31
Completion:: 2030-08-31

Conditions

Feeding Difficulties
Gastrostomy
Aspiration

Interventions

DRUG

No Results Yet

NCT06910774 | COMPLETED

100 participants

Analysis of Peripheral Serotonin Levels in a Control Cohort

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-06-23
Completion:: 2025-11-16

Conditions

No Condition : to Establish Reference Serum Serotonin Levels in a Control Cohort

Interventions

OTHER

No Results Yet

NCT06908434 | RECRUITING | PHASE1

82 participants

A Phase I First-in-Human Study of GenSci128 in Patients With Solid Tumors Harboring a TP53 Y220C Mutation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-06-10
Completion:: 2027-12-31

Conditions

Solid Tumors Harboring a TP53 Y220C Mutation

Interventions

DRUG

No Results Yet

NCT06892314 | COMPLETED

80 participants

Association Between CGM Metrics in Type 2 Diabetes Pregnancy and Perinatal Morbidity

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-05-15
Completion:: 2025-11-26

Conditions

Type 2 Diabetes Mellitus (T2DM)
Pregnancy

Interventions

BIOLOGICAL

No Results Yet

NCT06880367 | RECRUITING | NA

56 participants

Neuromodulatory Effects of Audio-proprio-phonatory Reinforcement Training on Subjective Tinnitus, Demonstrated by High-density Electroencephalogram (HD EEG)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-03-18
Completion:: 2028-09-18

Conditions

Tinnitus, Subjective

Interventions

BEHAVIORAL
DIAGNOSTIC_TEST

No Results Yet

NCT06872996 | RECRUITING | NA

100 participants

Trophallergen Prick Tests (PT) : Influence of Food Sample Shelf Life on the Reproducibility of PT Results

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-04-10
Completion:: 2027-10-10

Conditions

Food Allergy

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06842316 | RECRUITING

100 participants

Effects of Phytocannabinoids on Immune Response and Autophagy During Chronic Immune-mediated Inflammatory Diseases

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-04-10
Completion:: 2027-04-09

Conditions

Inflammatory Disorder of Immune System
Spondylitis, Ankylosing
Arthritis, Rheumatoid
Arthritis, Psoriatic
Inflammatory Bowel Diseases
Sjogren's Syndrome
Lupus Erythematosus, Systemic

Interventions

OTHER

No Results Yet

NCT06840743 | COMPLETED | NA

180 participants

Do Emotions and Pain Combined Affect Mechanical Pain Thresholds and Other Pain-related Variables

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-08-31
Completion:: 2025-10-30

Conditions

Pain Thresholds

Interventions

OTHER

No Results Yet

NCT06835049 | RECRUITING | PHASE2

24 participants

Feasibility of Total Neoadjuvant Treatment With HYPErthermia in Patients With High-risk Extremity and Trunk Soft Tissue Sarcoma (TNT-HYPE)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-10-27
Completion:: 2028-03-31

Conditions

Sarcoma,Soft Tissue

Interventions

DRUG
OTHER
RADIATION
PROCEDURE

No Results Yet

NCT06834113 | RECRUITING | NA

120 participants

Impact of Pain From Injectables Antiretroviral Treatments in HIV-1 Patients Based on the Injection Site (Ventrogluteal or Dorsogluteal) and the Use or Non-use of Virtual Reality Headset

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-01-24
Completion:: 2026-07-24

Conditions

HIV I Infection
Injection Pain

Interventions

PROCEDURE

No Results Yet

NCT06824779 | ACTIVE_NOT_RECRUITING | PHASE4

30 participants

Impact of FLU Vaccination on Nasal Resident Memory Immune Responses and Peripheral Respiratory-tropic Memory Immune Responses

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-12-05
Completion:: 2025-12-19

Conditions

Volunteers
Flu Vaccine

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT06824428 | COMPLETED

84 participants

The Pain Perception Threshold in Attention Deficit Disorder With Hyperactivity

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-02-16
Completion:: 2025-12-26

Conditions

Pain Threshold
Attention Deficit Disorder With Hyperactivity (ADHD)

Interventions

OTHER

No Results Yet

NCT06817018 | RECRUITING | PHASE2

80 participants

Ginger Root Extract for Sciatic Pain Individuals

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-07-01
Completion:: 2028-02-28

Conditions

Neuropathic Pain
Sciatic Pain

Interventions

DIETARY_SUPPLEMENT
DRUG

No Results Yet

NCT06813365 | RECRUITING | PHASE1

190 participants

Assessing an Oral EGFR Inhibitor, DZD6008 in Patients Who Have Advanced NSCLC With EGFR Mutations (TIAN-SHAN2)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2024-06-12
Completion:: 2026-12-30

Conditions

Nonsmall-cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT06813248 | RECRUITING

100 participants

Jigsaw Technique and Stroke Patient Care

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2024-12-15
Completion:: 2025-01-17

Conditions

Nursing
Education

No Results Yet

NCT06800352 | COMPLETED | NA

45 participants

The Effect of Olive Oil and Centaury Oil on Rash

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2024-12-30
Completion:: 2025-06-30

Conditions

Diaper Dermatitis

Interventions

OTHER

No Results Yet

NCT06798181 | RECRUITING

128 participants

Neuropathic Pain and Type II Diabetic Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2024-12-15
Completion:: 2025-06-15

Conditions

Neuropathic Pain
Quality of Life
Diabetic Neuropathies

No Results Yet

NCT06788886 | RECRUITING | NA

147 participants

Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-02-05
Completion:: 2027-01-18

Conditions

Malignant Brain Neoplasm
Malignant Solid Neoplasm
Multiple Sclerosis
Neuroendocrine Tumor
Prostate Carcinoma

Interventions

PROCEDURE
OTHER

No Results Yet

NCT06785779 | RECRUITING

77 participants

Short-term Treatment Satisfaction in Hidradenitis Suppurativa Patients Initiated on Cosentyx in Routine Clinical Practice in Saudi Arabia

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-03-10
Completion:: 2026-09-30

Conditions

Hidradenitis Suppurativa (HS)

Interventions

OTHER

No Results Yet

NCT06781905 | RECRUITING

20 participants

Description of Neurocognitive and Psychiatric Disorders Associated With Targeted Therapies Used in the Treatment of Lung Cancers With ALK/ROS1 Fusion and Their Impact on Patients' Quality of Life: Construction of an Experimental Patient-researcher Collaborative Care and Research Pathway

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-01-16
Completion:: 2027-05-09

Conditions

Metastatic Lung Cancer
Metastatic Lung Cancer With ALK/ROS1 Fusion

Interventions

OTHER

No Results Yet

NCT06778837 | COMPLETED

30 participants

Lymphedema Sensor Technology Development Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-01-27
Completion:: 2025-12-03

Conditions

Lymphedema Arm
Lymphedema
Cancer

Interventions

DEVICE

No Results Yet

NCT06746220 | RECRUITING | NA

120 participants

Effect of Physical Activity and/or Probiotics on Body Composition and Physiological Parameters in Women

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2024-09-16
Completion:: 2027-09-15

Conditions

Healthy Women

Interventions

OTHER

No Results Yet

NCT06744075 | ACTIVE_NOT_RECRUITING | NA

108 participants

Study of the Clearance of Minimal Residual Disease Measured at the End of First-line Treatment in Patients With Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2024-12-24
Completion:: 2027-12-20

Conditions

B-cell Lymphoma
Hodgkin Lymphoma

Interventions

OTHER

No Results Yet

NCT06741683 | COMPLETED | PHASE2/PHASE3

187 participants

A Study of Dengue Tetravalent Vaccine (TDV) in Healthy Participants in Japan

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2025-01-31
Completion:: 2025-07-09

Conditions

Dengue Fever

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT06725667 | COMPLETED | NA

50 participants

Ultrasound-Guided Transversalis Fascia Plane Block Versus Caudal Block for Postoperative Analgesia in Children Undergoing Inguinal Herniorrhaphy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2024-12-11
Completion:: 2025-12-06

Conditions

Ultrasound
Transversalis Fascia Plane Block
Caudal Block
Postoperative Analgesia
Children
Inguinal Herniorrhaphy

Interventions

OTHER

No Results Yet

NCT06725602 | ENROLLING_BY_INVITATION | NA

40 participants

Efficacy of Prehospital Tourniquet Models for Arterial Occlusion in Upper and Lower Limbs

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2024-12-07
Completion:: 2026-12-31

Conditions

Hemorrhage
Hypovolemic Shock
Tourniquets

Interventions

DEVICE

No Results Yet

NCT06723041 | RECRUITING | NA

78 participants

Acupressure for the Reduction of Anxiety in Patients Receiving Cancer-Directed Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2024-12-11
Completion:: 2026-12-31

Conditions

Hematopoietic and Lymphatic System Neoplasm
Malignant Solid Neoplasm

Interventions

PROCEDURE
OTHER

No Results Yet

NCT06714825 | COMPLETED | PHASE1

39 participants

Study of HS235 for Assessing the Pharmacokinetics, Safety, and Pharmacodynamics in Overweight/Obese Healthy Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-30
Start Date:: 2024-11-28
Completion:: 2025-12-02

Conditions

Overweight and Obesity

Interventions

BIOLOGICAL
DRUG

No Results Yet