Clinical Trials

NCT04648254 | COMPLETED | PHASE1

51 participants

Oral Axl/Mer/CSF1R Selective Tyrosine Kinase Inhibitor in Patients With Advanced Solid Tumor

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2020-11-18

Completion:

2025-12-23

Conditions

• Solid Tumor
• Advanced Cancer
• Metastatic Cancer

Interventions

• DRUG

No Results Yet

NCT04639180 | ACTIVE_NOT_RECRUITING | PHASE3

687 participants

A Study to Evaluate Camrelizumab Plus Rivoceranib (Apatinib) as Adjuvant Therapy in Patients With Hepatocellular Carcinoma (HCC) at High Risk of Recurrence After Curative Resection or Ablation

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2021-04-01

Completion:

2026-07-31

Conditions

• Hepatocellular Carcinoma (HCC)

Interventions

• DRUG

No Results Yet

NCT04604067 | ACTIVE_NOT_RECRUITING | PHASE2

260 participants

Assessing a ctDNA and PET-oriented Therapy in Patients With DLBCL A Multicenter, Open-label, Phase II Trial.

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2021-06-25

Completion:

2026-07-30

Conditions

• Diffuse Large B-cell Lymphoma

Interventions

• DRUG

No Results Yet

NCT04582201 | COMPLETED | PHASE1

20 participants

A Clinical Trial to Evaluate the Safety of agenT-797 in COVID-19 Participants With ARDS

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2020-09-21

Completion:

2023-04-23

Conditions

• Respiratory Distress Syndrome, Adult

Interventions

• DRUG

No Results Yet

NCT04573439 | RECRUITING | NA

30 participants

Protein Requirements for Active Children

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2021-08-16

Completion:

2026-06-30

Conditions

• Healthy

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04490564 | COMPLETED

135 participants

Validation of Molecular Diagnostic Assays to Detect Cancer Biomarkers in Blood and Primary Tumor in HNSCC/NSCLC/Melanoma

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-30

Start Date:

2019-06-25

Completion:

2022-09-07

Conditions

• Head and Neck Squamous Cell Carcinoma
• Non Small Cell Lung Cancer
• Melanoma

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04480814 | COMPLETED

30 participants

Validation of Molecular Diagnostic Assays to Detect Cancer Biomarkers in Blood & Primary Tumor in ER+/HER2- MBC

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-30

Start Date:

2019-10-11

Completion:

2022-02-08

Conditions

• Breast Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04472260 | RECRUITING | NA

32 participants

Early Verticalization of the Patient With Acute Respiratory Distress Syndrome: Assessment of Feasibility and Safety.

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2021-10-15

Completion:

2026-07-14

Conditions

• Acute Respiratory Distress Syndrome
• Prone Position

Interventions

• PROCEDURE

No Results Yet

NCT04451499 | COMPLETED | NA

40 participants

The Effect of Adding Smartphone-based Platform to the Bariatric Surgery Preparation Process

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2020-12-28

Completion:

2022-10-01

Conditions

• Bariatric Surgery Candidate
• Nutritional and Metabolic Diseases

Interventions

• OTHER

No Results Yet

NCT04446728 | ACTIVE_NOT_RECRUITING | NA

18 participants

Implementation of Family Psychosocial Risk Assessment in Pediatric Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2021-01-01

Completion:

2026-12-31

Conditions

• Pediatric Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT04442048 | COMPLETED | PHASE3

195 participants

Immunization With IMM-101 vs Observation for Prevention of Respiratory and Severe COVID-19 Related Infections in Cancer Patients at Increased Risk of Exposure

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2020-10-01

Completion:

2024-05-07

Conditions

• Cancer
• Covid-19

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT04440592 | COMPLETED | PHASE2

76 participants

Study to Evaluate Efficacy, Safety, and Tolerability of MT-7117 in Subjects With Diffuse Cutaneous Systemic Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2021-02-05

Completion:

2024-01-17

Conditions

• Diffuse Cutaneous Systemic Sclerosis

Interventions

• DRUG

Results Available

NCT04434768 | ACTIVE_NOT_RECRUITING | PHASE1

10 participants

Evaluate the Safety and Explore Efficacy of Umbilical Cord Mesenchymal Stem Cells in Acute Ischemic Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2020-12-02

Completion:

2026-02-28

Conditions

• Acute Stroke

Interventions

• BIOLOGICAL

No Results Yet

NCT04421625 | COMPLETED | NA

1102 participants

Patients and Health Staff of Cancer Centres During the Covid-19 Pandemic

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2020-06-15

Completion:

2022-06-28

Conditions

• COVID-19

Interventions

• DIAGNOSTIC_TEST

Results Available

NCT04417023 | ENROLLING_BY_INVITATION

500 participants

B3 for NMD: Bench to Bedside and Back

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-30

Start Date:

2019-05-06

Completion:

2031-12-31

Conditions

• Neuromuscular Disease

Interventions

• OTHER

No Results Yet

NCT04402489 | COMPLETED | PHASE3

184 participants

Study to Evaluate Efficacy, Safety, and Tolerability of MT-7117 in Subjects With Erythropoietic Protoporphyria or X-Linked Protoporphyria

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2020-06-01

Completion:

2021-12-14

Conditions

• EPP
• XLP

Interventions

• DRUG

Results Available

NCT04359875 | COMPLETED | NA

22000 participants

A Phone-call With a Student/General Practitioner Team to Impact Morbidity of Chronic Patients During COVID-19 Containment

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2020-04-30

Completion:

2020-06-30

Conditions

• Cardiovascular Diseases
• Mental Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT04336644 | RECRUITING | NA

60 participants

Continuous Versus Intermittent cARdiac Electrical moNitorinG

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2023-11-21

Completion:

2026-12-31

Conditions

• Torsades de Pointe Caused by Drug
• Long QT Syndrome

Interventions

• DEVICE

No Results Yet

NCT04300764 | WITHDRAWN | NA

0 participants

Gamification to Increase Mobility in the Hospital

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2026-01-01

Completion:

2026-04-30

Conditions

• Coronary Artery Disease
• Coronary Heart Disease
• Hypertension
• Diabete Mellitus
• Dyslipidemias
• Obesity
• Heart Failure

Interventions

• BEHAVIORAL

No Results Yet

NCT04231708 | NOT_YET_RECRUITING | PHASE2

20 participants

Effects of Pharmacological Stress and rTMS on Executive Function in Opioid Use Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2026-10-31

Completion:

2028-12-31

Conditions

• Opioid Use Disorder

Interventions

• DRUG
• DEVICE

No Results Yet

NCT04230304 | TERMINATED | PHASE2

8 participants

Daratumumab and Ibrutinib for the Treatment of Relapsed or Refractory Chronic Lymphocytic Leukemia, DIRECT Study

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2020-11-11

Completion:

2023-05-01

Conditions

• Recurrent Chronic Lymphocytic Leukemia
• Recurrent Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
• Recurrent Small Lymphocytic Lymphoma
• Refractory Chronic Lymphocytic Leukemia
• Refractory Small Lymphocytic Lymphoma

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT04230174 | COMPLETED | PHASE4

22 participants

Effect of Ocrelizumab on Neuroinflammation in Multiple Sclerosis as Measured by 11C-PBR28 MR-PET Imaging of Microglia Activation

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2020-12-29

Completion:

2024-10-09

Conditions

• Multiple Sclerosis

Interventions

• DRUG

Results Available

NCT04227899 | ACTIVE_NOT_RECRUITING | NA

261 participants

LIFE-BTK Randomized Controlled Trial

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2020-08-18

Completion:

2023-08-17

Conditions

• Critical Limb Ischemia (CLI)

Interventions

• DEVICE

Results Available

NCT04188457 | COMPLETED

859 participants

Medical-economic Evaluation Comparing Intensive Outpatient Monitoring of Neuro-cardiovascular Diseases by Nurses, Doctors and Hospital and Private-sector Pharmacists, Compared to Usual Monitoring.

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-30

Start Date:

2020-10-15

Completion:

2025-10-09

Conditions

• Cerebrovascular Accidents
• Myocardial Infarction

Interventions

• OTHER

No Results Yet

NCT04160455 | RECRUITING

180 participants

Study of Autophagy and the Effects of GALIG Gene Products in HIV-1 Infected Patients Who Are Under Antiretroviral Therapy Since Primary-infection, Chronic Phase, or Never Treated.

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-30

Start Date:

2019-11-07

Completion:

2029-11-07

Conditions

• Autophagy
• Galectins
• HIV Infections
• Highly Active Antiretroviral Therapy

Interventions

• BIOLOGICAL

No Results Yet

NCT04041583 | RECRUITING

45 participants

Clinical and Radiological Outcomes of Posterior Cervical Fusion Supplemented With Interfacet Spacers

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-30

Start Date:

2019-09-01

Completion:

2026-08-31

Conditions

• Cervical Fusion

Interventions

• DEVICE

No Results Yet

NCT04022980 | COMPLETED | PHASE1

14 participants

Nivolumab Consolidation in Older (≥ 65) Patients With Primary CNS Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2020-03-31

Completion:

2025-01-21

Conditions

• Brain and Nervous System
• Eye and Orbit

Interventions

• DRUG

No Results Yet

NCT03993678 | COMPLETED | PHASE1/PHASE2

28 participants

Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With Advanced Solid Tumors.

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2020-10-12

Completion:

2025-07-15

Conditions

• Advanced Solid Tumors

Interventions

• DRUG
• DEVICE

No Results Yet

NCT03988608 | COMPLETED | PHASE2

20 participants

Study Assessed the Safety and Efficacy of Eltrombopag in Chinese Refractory or Relapsed Severe Aplastic Anemia (SAA) Subjects.

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2019-12-09

Completion:

2021-07-16

Conditions

• Aplastic Anemia

Interventions

• DRUG

Results Available

NCT03984708 | COMPLETED | NA

9 participants

New Therapeutic Strategy in ALS Based on Metabolic Status and Associated Metabolic Pathways.

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2020-01-27

Completion:

2023-01-10

Conditions

• Amyotrophic Lateral Sclerosis

Interventions

• OTHER

No Results Yet

NCT03956095 | COMPLETED

23 participants

Study of Nutritional Supplement Shakes in People About to Receive Their Debulking Surgery for Ovarian Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-30

Start Date:

2019-05-16

Completion:

2025-12-19

Conditions

• Debulking Surgery for Ovarian Cancer

Interventions

• DIETARY_SUPPLEMENT
• OTHER

No Results Yet

NCT03921554 | COMPLETED | PHASE2

54 participants

JAK Inhibitor Treatment in AGS

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2019-06-03

Completion:

2024-01-04

Conditions

• Aicardi Goutieres Syndrome

Interventions

• DRUG

Results Available

NCT03879252 | COMPLETED | PHASE3

76 participants

Tolerance of Teeth Brushing During Prolonged Aplasia

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2019-07-22

Completion:

2023-02-01

Conditions

• Aplasia

Interventions

• DEVICE
• DRUG

No Results Yet

NCT03837626 | COMPLETED | PHASE2/PHASE3

137 participants

ENAC Blockade and Arterial Stiffness

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2019-07-15

Completion:

2024-10-05

Conditions

• Overweight and Obesity
• Insulin Resistance

Interventions

• DRUG

Results Available

NCT03820947 | TERMINATED | NA

506 participants

VenaSeal Spectrum: Global Post-Market Randomized Controlled Trial

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2020-02-05

Completion:

2024-06-12

Conditions

• Venous Reflux

Interventions

• DEVICE
• PROCEDURE

Results Available

NCT03809000 | ACTIVE_NOT_RECRUITING | PHASE2

188 participants

A Study of Salvage Radiotherapy With or Without Enzalutamide in Recurrent Prostate Cancer Following Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2019-04-15

Completion:

2023-04-07

Conditions

• Prostate Cancer

Interventions

• RADIATION
• DRUG

Results Available

NCT03708003 | TERMINATED | PHASE2

30 participants

Ibrutinib lead-in Followed by Venetoclax Plus Ibrutinib in Patients With RR CLL

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2019-03-11

Completion:

2025-11-30

Conditions

• Relapsed/Refractory Chronic Lymphocytic Leukemia
• Chronic Lymphocytic Leukemia
• Leukemia

Interventions

• DRUG

No Results Yet

NCT03696017 | RECRUITING

120 participants

Opioid/Benzodiazepine Polydrug Abuse

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-30

Start Date:

2019-02-08

Completion:

2026-12-31

Conditions

• Polysubstance Abuse

Interventions

• OTHER

No Results Yet

NCT03694457 | COMPLETED | NA

90 participants

Comparison Between Anterior Approach (Deltopectoral) and Lateral Approach (Deltoid Splitting) in Shoulder Reverse Arthroplasty for Proximal Humerus Fracture

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-30

Start Date:

2018-11-26

Completion:

2023-12-31

Conditions

• Humeral Fracture
• Aged Patient
• Reversed Total Shoulder Arthroplasty
• Surgical Approach

Interventions

• PROCEDURE

No Results Yet

NCT03663348 | RECRUITING

500 participants

Registry of Patients With Takotsubo Syndrome

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-30

Start Date:

2009-09-11

Completion:

2028-09-01

Conditions

• Takotsubo Cardiomyopathy
• Broken Heart Syndrome
• Tako-tsubo Cardiomyopathy

No Results Yet