Clinical Trials Updated in 2025

NCT05388916 | COMPLETED

42 participants

A Real-world Study to Assess Safety and Effectiveness of Secukinumab in Pediatric Plaque Psoriasis Patients in China

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-09-08
Completion:: 2025-02-27

Conditions

Moderate to Severe Chronic Plaque Psoriasis

Interventions

OTHER

No Results Yet

NCT05380713 | COMPLETED | PHASE2

30 participants

......SMARTEST Trial......

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-05-03
Completion:: 2025-08-11

Conditions

Mesothelioma, Malignant

Interventions

DRUG

No Results Yet

NCT05356377 | COMPLETED

6 participants

Preliminary Study of Brain Effects of Palynziq-Related Changes in Phenylalanine in Individuals With PKU

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-05-25
Completion:: 2025-07-01

Conditions

Phenylketonurias

Interventions

DRUG

No Results Yet

NCT05321784 | TERMINATED | NA

1 participants

At-Home Dermoscopy Artificial Intelligence

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-09-27
Completion:: 2024-09-30

Conditions

Malignant Skin Neoplasm

Interventions

OTHER
PROCEDURE
DEVICE

Results Available

NCT05300581 | COMPLETED | NA

10 participants

Determining the Feasibility of Outpatient Parenteral Antibiotic Therapy for Persons Who Inject Opioids

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-03-16
Completion:: 2025-12-19

Conditions

Opioid Use Disorder

Interventions

OTHER

No Results Yet

NCT05265611 | COMPLETED | NA

115 participants

Syrian Refugee Young Adults as Community Mental Health Workers-Lebanon

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-03-11
Completion:: 2025-03-25

Conditions

Mental Health
Stress, Psychological

Interventions

BEHAVIORAL

No Results Yet

NCT05232474 | COMPLETED | NA

2271 participants

Using KomPas+ in the Treatment of Patients With Intermittent Claudication

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-10-01
Completion:: 2024-06-04

Conditions

Intermittent Claudication
Peripheral Arterial Disease

Interventions

DEVICE

No Results Yet

NCT05162326 | NOT_YET_RECRUITING | PHASE1

9 participants

BC-101 in Treatment of Nasolabial Fold Wrinkles

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2026-12-01
Completion:: 2027-12-30

Conditions

Nasolabial Fold Wrinkles

Interventions

BIOLOGICAL

No Results Yet

NCT05126225 | COMPLETED | NA

19 participants

Buddhist Understanding and Reduction of Myanmar Experiences of HIV Stigma and Exclusion

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2020-07-01
Completion:: 2023-11-19

Conditions

Hiv
Stigma, Social
Mindfulness

Interventions

BEHAVIORAL

Results Available

NCT05115188 | COMPLETED | PHASE2

31 participants

DIAgnosing GDM usiNg Oral Sugar InStead

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-10-01
Completion:: 2025-09-30

Conditions

Diabetes, Gestational

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05076565 | ACTIVE_NOT_RECRUITING | NA

200 participants

Wearable Airbag Technology to Mitigate Falls in Individuals With High Fall Risk

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2018-01-14
Completion:: 2026-12-14

Conditions

Falling
Fall Patients
Stroke
Parkinson Disease
Lower Limb Amputation Knee
Fall Injury

Interventions

DEVICE

No Results Yet

NCT05053997 | RECRUITING | NA

250 participants

Navigate - Improving Survival and Quality of Life in Vulnerable Lung Cancer Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-03-01
Completion:: 2026-12-31

Conditions

Lung Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT05044273 | RECRUITING

2000 participants

Evaluation of Effectiveness and Safety of Synergy XD and Synergy Megatron™ Stent

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-09-01
Completion:: 2026-12-31

Conditions

Coronary Artery Disease
Cardiovascular Diseases
Heart Diseases
Myocardial Ischemia
Coronary Disease

Interventions

DEVICE

No Results Yet

NCT05035160 | RECRUITING

1000 participants

UCLA Perinatal Biospecimen Repository

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2021-07-30
Completion:: 2028-12-31

Conditions

Pregnancy
High-Risk Pregnancy

No Results Yet

NCT05019976 | ACTIVE_NOT_RECRUITING | NA

30 participants

Radiation Dose Study for Relapsed/Refractory Hodgkin/Non-Hodgkin Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2021-09-30
Completion:: 2027-12-01

Conditions

Lymphoma
Non-hodgkin Lymphoma
Hodgkin Lymphoma

Interventions

RADIATION

No Results Yet

NCT05007782 | RECRUITING | PHASE1

416 participants

Study of Denikitug (GS-1811) Given Alone or With Zimberelimab in Adults With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2021-08-18
Completion:: 2028-12-31

Conditions

Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT04989907 | COMPLETED

92 participants

A Study in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) Receiving Vedolizumab in Real-World Practice in Switzerland

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2021-09-08
Completion:: 2024-05-17

Conditions

Inflammatory Bowel Diseases
Crohns Disease
Colitis, Ulcerative

No Results Yet

NCT04954664 | RECRUITING | NA

44 participants

Ridge Augmentation Using Allograft Particles Hydrated With or Without Recombinant Human Platelet-Derived Growth Factor

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2021-08-11
Completion:: 2026-12-31

Conditions

Dental Implant
Bone Loss

Interventions

BIOLOGICAL

No Results Yet

NCT04949360 | RECRUITING | NA

280 participants

SleepUp Digital CBTi-based Platform for Insomnia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-05-19
Completion:: 2025-11-18

Conditions

Insomnia
Sleep Disorder
Sleep Hygiene

Interventions

BEHAVIORAL

No Results Yet

NCT04927364 | COMPLETED | NA

8 participants

Examining the Effectiveness of Deep TMS in Veterans With Alcohol Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-09-06
Completion:: 2023-11-17

Conditions

Alcohol Use Disorder (AUD)
Transcranial Magnetic Stimulation

Interventions

DEVICE

Results Available

NCT04850391 | COMPLETED | NA

133 participants

Interaction of Sleep, Diurnal Eating Pattern, Gut Microbiota, and Obesity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2021-10-01
Completion:: 2024-10-21

Conditions

Obesity
Obesity & Overweight

Interventions

OTHER

No Results Yet

NCT04840706 | TERMINATED | NA

3 participants

Open-Label Prospective Study Comparing Long-Term Outcome With or Without HFNC in Patients With Stable Hypercapnic COPD

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-04-21
Completion:: 2024-04-30

Conditions

COPD

Interventions

DEVICE
OTHER

No Results Yet

NCT04769362 | RECRUITING | PHASE4

2540 participants

Long-term Beta-blocker Therapy After Acute Myocardial Infarction

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2021-05-04
Completion:: 2026-01-31

Conditions

Myocardial Infarction

Interventions

DRUG

No Results Yet

NCT04683653 | RECRUITING | PHASE1/PHASE2

100 participants

Study of Pelvic Hypofractionated Radiotherapy in Endometrial Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2021-01-15
Completion:: 2027-05-22

Conditions

Endometrial Cancer

Interventions

RADIATION
OTHER

No Results Yet

NCT04636710 | RECRUITING | NA

50 participants

Refining Local-Regional Therapy for IBC

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2021-06-02
Completion:: 2027-12-01

Conditions

Breast Cancer
Inflammatory Breast Cancer
Sentinel Lymph Node

Interventions

PROCEDURE

No Results Yet

NCT04523194 | ACTIVE_NOT_RECRUITING

1000 participants

Massachusetts General Hospital and Tsuchiura Kyodo General Hospital Coronary Imaging Collaboration

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2020-11-09
Completion:: 2025-12-19

Conditions

Atherosclerosis

Interventions

OTHER

No Results Yet

NCT04452097 | WITHDRAWN | PHASE1/PHASE2

0 participants

Use of hUC-MSC Product (BX-U001) for the Treatment of COVID-19 With ARDS

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2026-06-01
Completion:: 2027-07-01

Conditions

COVID-19
ARDS
Acute Respiratory Distress Syndrome

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT04428489 | ENROLLING_BY_INVITATION

300 participants

Follow-up Study of ICUS and CCUS Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2011-01-01
Completion:: 2026-12-31

Conditions

Myelodysplastic Syndromes

Interventions

OTHER

No Results Yet

NCT04409197 | COMPLETED

4789 participants

Evaluation of Changes in Weight, Sleep, and Other Psycho-behavioural Parameters During Covid-19 Confinement in Subjects Monitored by the RNPC Network

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2020-05-08
Completion:: 2020-06-08

Conditions

Comorbidities
Confinement
Obesity

No Results Yet

NCT04279652 | COMPLETED | NA

30 participants

Exercise in Children Attention Deficit Hyperactivity Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2019-10-10
Completion:: 2022-08-10

Conditions

ADHD
Exercise

Interventions

OTHER

No Results Yet

NCT04274348 | COMPLETED | NA

41 participants

Staphylococcal Toxins in Atopic Dermatitis and Eczema Herpeticum

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2020-10-15
Completion:: 2025-08-04

Conditions

Atopic Dermatitis
Staphylococcus Aureus
Bacterial Toxins
Immune Response
Cytokines
T Cells Subsets

Interventions

OTHER

No Results Yet

NCT04223817 | COMPLETED | NA

50 participants

7.0 Tesla Resonance Magnetic Imaging of the Hand in Systemic Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2021-04-12
Completion:: 2025-09-02

Conditions

Systemic Sclerosis (SSc)
Magnetic Resonance Imaging (MRI)

Interventions

DEVICE

No Results Yet

NCT04219670 | RECRUITING

400 participants

Inpatient Stroke Recovery Using Sensors

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2017-10-31
Completion:: 2026-12-31

Conditions

Stroke

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04045496 | COMPLETED | PHASE1

40 participants

A First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2019-09-26
Completion:: 2022-12-16

Conditions

Non-small Cell Lung Cancer
Colorectal Cancer
Pancreatic Ductal Carcinoma
Esophageal Squamous Cell Carcinoma
Head and Neck Squamous Cell Carcinoma
Breast Cancer
Other Solid Tumors

Interventions

DRUG

No Results Yet

NCT03992651 | COMPLETED | NA

20 participants

Optical Transcutaneous Sensors of Capnia and Oxygenation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2019-06-12
Completion:: 2019-06-13

Conditions

Blood Gas Monitoring, Transcutaneous

Interventions

DEVICE

No Results Yet

NCT03875755 | ACTIVE_NOT_RECRUITING | NA

1080 participants

Myo-inositol for Reduction of Insulin Therapy in Gestational Diabetes Mellitus

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2020-03-04
Completion:: 2026-09-20

Conditions

Gestational Diabetes Mellitus

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT03869216 | COMPLETED | NA

161 participants

Fostering Shared Decision-making About Prostate Cancer Screening Among Clinicians and African American Men

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2020-08-17
Completion:: 2023-11-30

Conditions

Prostate Cancer

Interventions

BEHAVIORAL

Results Available

NCT03857191 | COMPLETED

396 participants

Nutritional Rehabilitation and Sleep Apnea in the Obese

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2019-03-22
Completion:: 2022-04-11

Conditions

Obese
Sleep Apnea, Obstructive

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT03780062 | COMPLETED | PHASE3

720 participants

Interest of S100B Protein for Patient Victim of Minor Traumatic Brain Injury and Treated by Antiplatelet

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2019-01-25
Completion:: 2025-04-28

Conditions

Minor Traumatic Brain Injury
Treatment by Antiplatelet

Interventions

BIOLOGICAL

No Results Yet

NCT03760731 | COMPLETED | NA

74 participants

Thriving in the Midst of Moral Pain: The Acceptability and Feasibility of Acceptance and Commitment Therapy for Moral Injury (ACT-MI) Among Warzone Veterans

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2019-04-01
Completion:: 2024-10-31

Conditions

Moral Injury

Interventions

BEHAVIORAL

Results Available