Clinical Trials Updated in 2025

NCT06792344 | RECRUITING | PHASE1

12 participants

Clinical Study of CD19 CAR-T in the Treatment of Refractory Systemic Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-12-15
Completion:: 2027-12-30

Conditions

Systemic Sclerosis (SSc)

Interventions

OTHER
DRUG

No Results Yet

NCT06788015 | COMPLETED | NA

10 participants

Hydrogen-Infused Water for Endurance Performance, Body Hydration Biomarkers, and Health-Related Quality of Life

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-11-15
Completion:: 2025-02-28

Conditions

Exercise Overtraining

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06778434 | RECRUITING | PHASE2

48 participants

The Effect of Topical Imipramine on Photodynamic Therapy-Mediated Immunosuppression on Forearms or Face on US Veterans

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2025-04-01
Completion:: 2029-03-30

Conditions

Actinic Keratosis
Imipramine
Photodynamic Therapy

Interventions

DRUG
OTHER

No Results Yet

NCT06770543 | RECRUITING

1500 participants

Leqvio rPMS (Regulatory Post-Marketing Surveillance in Korea)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-22
Start Date:: 2025-08-13
Completion:: 2031-01-02

Conditions

Primary Hypercholesterolemia or Mixed Dyslipidemia

Interventions

OTHER

No Results Yet

NCT06764342 | COMPLETED | NA

40 participants

Adjunctive Effect of Photodynamic Therapy on Halitosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2025-01-08
Completion:: 2025-02-22

Conditions

Periodontitis
Halitosis

Interventions

RADIATION
PROCEDURE

No Results Yet

NCT06764082 | RECRUITING | NA

120 participants

Nutritional Intervention for Biliary Atresia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2025-02-01
Completion:: 2028-06-30

Conditions

Nutrition Disorder, Infant
Biliary Atresia

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06714110 | ENROLLING_BY_INVITATION

200 participants

A Review of Precice Intramedullary Limb Lengthening (IMLL) System for Limb Lengthening Procedures in Children.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-22
Start Date:: 2025-03-13
Completion:: 2026-07-30

Conditions

Limb Length Discrepancy

Interventions

DEVICE

No Results Yet

NCT06705400 | RECRUITING | NA

3500 participants

The Bloom Study - a Safe and Healthy Start in Life

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-11-01
Completion:: 2029-03-31

Conditions

Overweight, Childhood
Obesity in Children

Interventions

BEHAVIORAL

No Results Yet

NCT06686667 | COMPLETED | NA

31 participants

The Feasibility of Overnight Time Restricted Eating and Impact on Glucose Levels in Shift Workers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2025-03-24
Completion:: 2025-07-10

Conditions

Shift Work
Eating Behaviors

Interventions

BEHAVIORAL

No Results Yet

NCT06685640 | RECRUITING | NA

10 participants

Comparison of Clinical Success of Stainless Steel Crowns and Zirconia Crowns in Primary Molars

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-07-30
Completion:: 2026-08-30

Conditions

Dental Caries
Pulpotomy

Interventions

OTHER

No Results Yet

NCT06659146 | RECRUITING | NA

60 participants

Thermotherapy in Addition to SOC Palliative Radiotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-10-14
Completion:: 2028-03-01

Conditions

Head and Neck Squamous Cell Carcinoma
Cutaneous Squamous Cell Carcinoma
Breast Cancer Recurrent

Interventions

DEVICE

No Results Yet

NCT06613620 | COMPLETED | NA

46 participants

Additional Effects of Surface Electromyographic Biofeedback on Post Facilitation Stretching and Strengthening in Lower Crossed Syndrome;A Randomized Control Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-07-18
Completion:: 2025-06-02

Conditions

Lower Cross Syndrome

Interventions

OTHER

No Results Yet

NCT06576440 | COMPLETED | NA

24 participants

Effects of Ghrelin Administration on Motivation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-09-02
Completion:: 2024-12-20

Conditions

Major Depressive Disorder

Interventions

DRUG

No Results Yet

NCT06571994 | COMPLETED | NA

60 participants

The Plastic Exposure Reduction Transforms Health Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-09-05
Completion:: 2025-07-03

Conditions

Endocrine Disruptors
Inflammation
Cardiometabolic Risk Factors

Interventions

BEHAVIORAL

No Results Yet

NCT06540326 | RECRUITING | PHASE2

100 participants

Clinical Study of Second-line Treatment in Advanced Colorectal Cancer With Chemotherapy With Bevacizumab or Cetuximab

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-11-12
Completion:: 2026-04-15

Conditions

Colorectal Cancer Metastatic

Interventions

DRUG

No Results Yet

NCT06523608 | RECRUITING

600 participants

Prediction of Decompensation and HCC Development in Advanced Chronic Liver Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-09-01
Completion:: 2027-09-30

Conditions

Liver Diseases
Hepatocellular Carcinoma
Hepatocarcinoma
Advanced Chronic Liver Disease

Interventions

OTHER

No Results Yet

NCT06522204 | COMPLETED | NA

60 participants

Comparing the Gastric Emptying Times of Underweight and Healthy-weight School-aged Children

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-07-30
Completion:: 2025-12-15

Conditions

Preoperative Fasting

Interventions

DRUG

No Results Yet

NCT06513208 | RECRUITING | PHASE4

140 participants

Ketorolac Effects on Post-operative Pain and Lumbar Fusion

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2026-01-31
Completion:: 2027-06-30

Conditions

Lumbar Spinal Fusion

Interventions

DRUG

No Results Yet

NCT06493604 | COMPLETED | PHASE3

116 participants

A Trial to Assess the Safety and Efficacy of Subjects With Dry Eye Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-06-24
Completion:: 2025-02-27

Conditions

Dry Eye Disease

Interventions

DRUG

No Results Yet

NCT06487585 | RECRUITING | PHASE4

100 participants

ANG-First Trial (Angiotensin II as First-Line Vasopressor Therapy in Cardiac Surgery)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2025-05-06
Completion:: 2026-01-31

Conditions

Vasodilatory Hypotension During or After Cardiac Surgery

Interventions

DRUG

No Results Yet

NCT06468124 | RECRUITING

20 participants

Sensitivity of Organoids to Predict Treatment Outcome in Breast Cancer Metastases

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-22
Start Date:: 2025-05-27
Completion:: 2026-06-30

Conditions

Breast Neoplasms

No Results Yet

NCT06462391 | ACTIVE_NOT_RECRUITING | NA

50 participants

Adapting and Piloting Acceptance and Commitment Therapy (ACT) for Severe Premenstrual Mood Symptoms

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-12-01
Completion:: 2026-06-30

Conditions

Premenstrual Dysphoric Disorder
Premenstrual Exacerbation of Mood Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06435468 | RECRUITING | NA

400 participants

Biocollection of Rare Pediatric-onset of Autoimmune and Autoinflammatory Diseases

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2025-02-26
Completion:: 2035-02-27

Conditions

Systemic Lupus
Autoimmune Diseases
Autoinflammatory Disease
Genetic Disease

Interventions

GENETIC
OTHER

No Results Yet

NCT06420349 | TERMINATED | PHASE1

7 participants

NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-05-31
Completion:: 2025-08-12

Conditions

Advanced Cholangiocarcinoma
Metastatic Cholangiocarcinoma
Refractory Cholangiocarcinoma
Stage III Hilar Cholangiocarcinoma AJCC v8
Stage III Intrahepatic Cholangiocarcinoma AJCC v8
Stage IV Hilar Cholangiocarcinoma AJCC v8
Stage IV Intrahepatic Cholangiocarcinoma AJCC v8

Interventions

PROCEDURE
BIOLOGICAL

No Results Yet

NCT06414330 | COMPLETED | PHASE3

124 participants

Ringer Acetate Based Modified Del Nido Cardioplegia Solution Versus HTK Solution Cardioplegia Solution in Cardiac Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-06-01
Completion:: 2025-11-12

Conditions

Cardiac Ischemia

Interventions

BIOLOGICAL

No Results Yet

NCT06408506 | COMPLETED | NA

20 participants

In-patient Comparison of Immediately Loaded and Non-loaded Submerged and Transgingival Healed Implants Within 4 Months

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2017-09-28
Completion:: 2025-10-29

Conditions

Jaw, Edentulous

Interventions

PROCEDURE

No Results Yet

NCT06389656 | COMPLETED | NA

17 participants

Addressing Weight Bias Internalization to Improve Adolescent Weight Management Outcomes: Open Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-04-08
Completion:: 2025-02-15

Conditions

Body Weight
Weight Bias
Weight Stigma
Weight

Interventions

BEHAVIORAL

No Results Yet

NCT06377215 | RECRUITING | NA

121 participants

Understanding Aided Speech Perception in Noise

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2025-11-16
Completion:: 2028-03-01

Conditions

Hearing Impairment, Sensorineural
Spatial Perception
Aging
Hearing Aids

Interventions

DEVICE

No Results Yet

NCT06368427 | COMPLETED

10 participants

Change in Patient-repOrted Outcomes in COPD Patients Newly Initiated on TRIXEO AEROSPHERE in Real worlD

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-04-30
Completion:: 2025-11-17

Conditions

Chronic Obstructive Pulmonary Disease (COPD)

Interventions

DRUG

No Results Yet

NCT06349512 | RECRUITING | NA

60 participants

68Ga-FAPI-46 PET/CT for Predicting Histological Response in Triple-negative Breast Cancer (FAP-IT)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-10-14
Completion:: 2032-11-30

Conditions

Triple Negative Breast Cancer

Interventions

PROCEDURE

No Results Yet

NCT06341452 | RECRUITING | NA

130 participants

Comparison of Individualized Sodium Management Versus Standard Treatment in Hemodialysis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2025-12-16
Completion:: 2026-12-31

Conditions

End Stage Renal Disease

Interventions

DEVICE

No Results Yet

NCT06332144 | COMPLETED | NA

41 participants

Predicting Language and Literacy Growth in Children With ASD Using Statistical Learning

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-01-13
Completion:: 2025-08-31

Conditions

Autism Spectrum Disorder
Language Development
Literacy

Interventions

BEHAVIORAL

No Results Yet

NCT06327074 | ACTIVE_NOT_RECRUITING | NA

40 participants

Testing the Engaged Approach to Lung Cancer Screening

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-03-11
Completion:: 2024-10-30

Conditions

Lung Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06323109 | RECRUITING

80 participants

US Imaging for the Assessment of LUTS

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-22
Start Date:: 2023-11-28
Completion:: 2027-01-31

Conditions

Lower Urinary Tract Symptoms
BPH

Interventions

DEVICE

No Results Yet

NCT06310005 | COMPLETED | PHASE1

36 participants

A Study in Healthy Japanese Men to Test How Well Different Doses of BI 3006337 Are Tolerated

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-04-19
Completion:: 2024-10-31

Conditions

Healthy

Interventions

DRUG

Results Available

NCT06306586 | RECRUITING | NA

60 participants

A Digital Treatment for Adolescents With Eating Disorders

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-03-11
Completion:: 2027-01-01

Conditions

Eating Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT06302439 | RECRUITING

1000 participants

PROPEL - A Prospective Observational Patient Registry to Evaluate ENPP1 and ABCC6 Deficiency

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-07-25
Completion:: 2034-05-31

Conditions

Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 Deficiency
ATP-Binding Cassette Subfamily C Member 6 Deficiency

Interventions

OTHER

No Results Yet

NCT06270602 | RECRUITING

15000 participants

The ONCOCAMP Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-22
Start Date:: 2023-07-14
Completion:: 2026-05-31

Conditions

Oncology

Interventions

OTHER

No Results Yet

NCT06255353 | COMPLETED | NA

118 participants

Effect of Different Feeding Modes in Intracerebral Hemorrhage

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-02-28
Completion:: 2025-10-19

Conditions

Intracerebral Hemorrhage

Interventions

DEVICE
BEHAVIORAL

No Results Yet

NCT06247189 | RECRUITING | NA

30 participants

ICOPE Program Feasibility in the Management of Myeloma Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2025-12-03
Completion:: 2026-12-03

Conditions

Frailty
Multiple Myeloma

Interventions

OTHER

No Results Yet