Clinical Trials Updated in 2025

NCT07059312 | ACTIVE_NOT_RECRUITING | PHASE1

32 participants

A Phase 1 Study of JADE101 in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-08-17
Completion:: 2026-10-31

Conditions

Healthy Volunteers

Interventions

DRUG

No Results Yet

NCT07057479 | WITHDRAWN | PHASE3

0 participants

Phase III Trial of SGLT2 Inhibitor and Thiazolidinedione Fixed-Dose Combination vs. Monotherapy in Type 2 Diabetes Patients on Metformin

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2026-09-30
Completion:: 2028-02-29

Conditions

Type 2 Diabetes Mellitus (T2DM)

Interventions

DRUG

No Results Yet

NCT07054606 | COMPLETED | PHASE4

104 participants

A Study to Evaluate Concomitant Perfluorohexyloctane Use With Contact Lens Wear

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-07-02
Completion:: 2025-11-03

Conditions

Dry Eye

Interventions

DRUG

No Results Yet

NCT07038122 | ACTIVE_NOT_RECRUITING | NA

874 participants

Reducing the Resection Range After Neoadjuvant Therapy for Locally Advanced Upper Rectal and Rectosigmoid Junction Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-07-01
Completion:: 2027-06-20

Conditions

Locally Advanced Rectal Carcinoma

Interventions

PROCEDURE
OTHER

No Results Yet

NCT07035977 | COMPLETED | NA

138 participants

DeepPriorCBCT for Low Dose Lung CBCT Reconstruction

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-05-15
Completion:: 2025-07-15

Conditions

Lung Nodules

Interventions

RADIATION

No Results Yet

NCT07031765 | ACTIVE_NOT_RECRUITING | PHASE1

12 participants

Peds CHAMP1ON - Hematopoietic Stem Cell And Monoclonal Antibody PD-1 Blockade for RecurreNt Pediatric High-Grade Glioma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-07-25
Completion:: 2030-12-31

Conditions

Recurrent High-grade Glioma
Grade III Astrocytoma
Oligodendroglioma
Oligoastrocytoma
Ependymoma
Grade IV Astrocytoma

Interventions

BIOLOGICAL
DRUG
PROCEDURE

No Results Yet

NCT07030907 | RECRUITING | PHASE1

30 participants

A Study to Evaluate the Safety and Efficacy of OPB-101 in Platinum-resistant Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-06-16
Completion:: 2028-05-15

Conditions

Ovarian Cancer Recurrent
Ovarian Cancer
Platinum Resistant Ovarian Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT07019376 | COMPLETED | NA

48 participants

Investigation of the Effects of Lumbopelvic Movement Training on Different Parameters in Healthy Sedentary Individuals

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-06-04
Completion:: 2025-11-29

Conditions

Exercise Training

Interventions

OTHER

No Results Yet

NCT07017283 | RECRUITING | NA

170 participants

Effect of Deep Analgosedation vs. Endotracheal Intubation General Anesthesia on on Perioperative Sedation Related Adverse Events in Elderly ERCP Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-11-10
Completion:: 2026-02-28

Conditions

Biliary and Pancreatic Diseases
Endoscopic Retrograde Cholangiopancreatography (ERCP)

Interventions

DEVICE

No Results Yet

NCT07016646 | COMPLETED | NA

40 participants

SH+ and Cash Assistance

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-06-20
Completion:: 2025-08-20

Conditions

Stress
Depression Symptoms

Interventions

COMBINATION_PRODUCT
OTHER

No Results Yet

NCT07010679 | ENROLLING_BY_INVITATION | NA

50 participants

Treatment Decision-Making Among Patients With Chronic Rhinosinusitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-06-02
Completion:: 2026-03-31

Conditions

Chronic Rhinosinusitis (CRS)

Interventions

OTHER

No Results Yet

NCT07006883 | RECRUITING | NA

90 participants

Effects of a Yoga Program on the Functionality of Individuals

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-08-01
Completion:: 2029-01-30

Conditions

Knee Osteoarthritis

Interventions

OTHER

No Results Yet

NCT07004686 | RECRUITING | NA

112 participants

Effect of MGRNOX-Guided General Anesthesia on Opioid Consumption in Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-06-28
Completion:: 2026-05-30

Conditions

Opioid Use

Interventions

DEVICE

No Results Yet

NCT07003321 | RECRUITING | PHASE2

120 participants

A Trial of HRS-4508 in Subjects With Locally Advanced or Metastatic Non-small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-09-12
Completion:: 2027-09-30

Conditions

Solid Tumor

Interventions

DRUG

No Results Yet

NCT06983470 | RECRUITING | NA

15 participants

Predictive Utility and Mechanisms of Sacral Evoked Responses in Sacral Neuromodulation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-10-16
Completion:: 2028-09-30

Conditions

Overactive Bladder

Interventions

DEVICE

No Results Yet

NCT06974773 | RECRUITING | NA

120 participants

Remote Electrical Stimulation as a Long-term Intervention for Endometriosis Flare Ups

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-12-04
Completion:: 2026-07-01

Conditions

Endometriosis

Interventions

DEVICE

No Results Yet

NCT06972992 | COMPLETED | PHASE1

28 participants

A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASC47 in Combination With Semaglutide

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-04-18
Completion:: 2025-09-22

Conditions

Chronic Weight Management

Interventions

DRUG

No Results Yet

NCT06971705 | ACTIVE_NOT_RECRUITING | NA

40 participants

fMRI Study on Cerebral Localization and Network Mechanisms of rTMS in Chronic Ankle Instability Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-03-20
Completion:: 2026-05-20

Conditions

Chronic Ankle Instability, CAI
Functional Magnetic Resonance Imaging (fMRI)

Interventions

DEVICE
BEHAVIORAL

No Results Yet

NCT06946303 | COMPLETED

24 participants

Identifying Key Attributes and Learning From a Local Falls Prevention Ambassador Programme

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-18
Start Date:: 2024-08-13
Completion:: 2025-09-30

Conditions

Long Term Care

Interventions

OTHER

No Results Yet

NCT06940713 | RECRUITING | NA

76 participants

Prospective Study of the Feasibility of Brain Connectivity Imaging by Functional Ultrasound Imaging (fUS) in Newborn Infant

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-11-28
Completion:: 2030-04-30

Conditions

Neonates and Preterm Infants
Neonates or Premature Babies

Interventions

DEVICE

No Results Yet

NCT06938802 | COMPLETED | NA

40 participants

Pilot Study of App-delivered Sleep Coaching Among Cancer Survivors and Their Partners

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-07-21
Completion:: 2025-12-16

Conditions

Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06931665 | RECRUITING | NA

26 participants

Neurological and Physiological Effects of Animal-assisted Therapy for Patients in a Minimally Conscious State

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-07-08
Completion:: 2027-04-30

Conditions

Minimally Conscious State

Interventions

PROCEDURE

No Results Yet

NCT06924801 | RECRUITING | NA

30 participants

Integration of Real-Time Motion Tracking and Pediatric Rehabilitation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-10-15
Completion:: 2026-09-30

Conditions

Rehabilitation

Interventions

BEHAVIORAL

No Results Yet

NCT06922669 | RECRUITING | NA

232 participants

Glucocorticoids for Acute Drug Induced Liver Injury With Hyperbilirubinemia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-06-24
Completion:: 2027-03-31

Conditions

Drug Induced Liver Injury

Interventions

DRUG
PROCEDURE

No Results Yet

NCT06917378 | RECRUITING

5000 participants

TRIO CTO (Taiwan Research Initiative on Coronary Total Occlusion)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-18
Start Date:: 2017-01-01
Completion:: 2034-12-31

Conditions

Chronic Total Occlusion (CTO)

Interventions

PROCEDURE

No Results Yet

NCT06915090 | COMPLETED | NA

15 participants

FIT-COACH: Fitbit Intervention With Coordinated Health Coaching and PCP Support

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-03-18
Completion:: 2025-09-30

Conditions

GLP - 1
Diabetes
Obesity and Obesity-related Medical Conditions
Cardiovascular Diseases

Interventions

BEHAVIORAL

No Results Yet

NCT06914622 | RECRUITING | NA

72 participants

Real-time Experiences, Physical Activity and Biological Outcomes in Personal Recovery Residents (EMPOWER-RES)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2026-01-15
Completion:: 2027-12-31

Conditions

Severe Mental Disorder
Severe Mental Illness

Interventions

BEHAVIORAL

No Results Yet

NCT06910384 | TERMINATED | PHASE2

1 participants

A Study of STRO4 in Patients Amyotrophic Lateral Sclerosis (ALS)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-08-12
Completion:: 2025-12-16

Conditions

Amyotrophic Lateral Sclerosis

Interventions

BIOLOGICAL

No Results Yet

NCT06865989 | COMPLETED | NA

132 participants

Omnipod® SmartAdjust 2.0 System Compared to the Omnipod® 5 System in Individuals With Type 1 or Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-03-26
Completion:: 2025-11-10

Conditions

Diabetes Mellitus, Type 1, Type 2

Interventions

DEVICE

No Results Yet

NCT06865105 | RECRUITING | PHASE2

120 participants

Study of Targeted Therapies for the Treatment of Adult Participants With Active Psoriatic Arthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-04-11
Completion:: 2027-12-31

Conditions

Psoriatic Arthritis

Interventions

DRUG

No Results Yet

NCT06851793 | COMPLETED

110 participants

Investigating Postural Parameters in Different Hip Pathologies

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-10-02
Completion:: 2025-11-10

Conditions

Hip Injuries and Disorders

No Results Yet

NCT06847646 | COMPLETED | NA

74 participants

Evaluation of Bioflex Crowns Using the Hall Technique in Primary Molars

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2024-08-20
Completion:: 2025-08-20

Conditions

BioFlex Crowns Using Hall Technique

Interventions

OTHER

No Results Yet

NCT06833281 | TERMINATED | PHASE2

12 participants

Extension Study of Participants From SPG302-ALZ-101

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-03-25
Completion:: 2025-07-30

Conditions

Alzheimer's Disease

Interventions

DRUG

No Results Yet

NCT06827860 | RECRUITING | PHASE2

23 participants

Subcutaneous Talquetamab in Elderly Patients With Multiple Myeloma in Early Relapse

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-11-18
Completion:: 2027-01-31

Conditions

Multiple Myeloma in Relapse

Interventions

DRUG

No Results Yet

NCT06825494 | RECRUITING | PHASE1/PHASE2

194 participants

Clinical Studies for the Treatment of Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-04-08
Completion:: 2026-03-31

Conditions

Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT06823388 | COMPLETED | NA

30 participants

Assessment of Acupuncture on Eye Fatigue

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2024-08-01
Completion:: 2024-12-30

Conditions

Acupuncture
Eye Fatigue
Accomodation

Interventions

DEVICE

No Results Yet

NCT06821126 | RECRUITING | PHASE1/PHASE2

238 participants

Study Comparing Safety and Immunogenicity of Intranasal COVID-19 Vaccine and mRNA Booster in Healthy Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-05-09
Completion:: 2026-10-31

Conditions

Healthy

Interventions

BIOLOGICAL

No Results Yet

NCT06817421 | NOT_YET_RECRUITING | PHASE4

214 participants

Opportunistic Pneumococcal Immunisation Trial in MALnutrition

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2026-01-31
Completion:: 2028-03-31

Conditions

Severe Acute Malnutrition in Childhood
Pneumococcal Disease
Pneumococcal Vaccines
Pneumococcal Infection
Pneumonia in Children

Interventions

BIOLOGICAL

No Results Yet

NCT06799702 | NOT_YET_RECRUITING | NA

50 participants

Trauma-informed, Resilience-based Telehealth Intervention for Improving HIV Prevention and HCV Care for Persons Who Inject Drugs in the Deep South (Pilot Testing: Aim3)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2026-08-01
Completion:: 2028-03-31

Conditions

HIV Pre-exposure Prophylaxis
HEPATITIS C (HCV)
Opioid Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06797817 | NOT_YET_RECRUITING | PHASE3

156 participants

Tributyrin Treatment in Mild Alzheimer Disease: Assessment of Butyrate Effects Via the Gut-Brain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2026-06-01
Completion:: 2026-09-01

Conditions

Alzheimer Disease (AD)

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet