Clinical Trials Updated in 2025

NCT07236944 | RECRUITING | PHASE4

560 participants

Pivmecillinam as Oral Step-Down Treatment for Escherichia Coli Febrile Urinary Tract Infection Versus Standard of Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-12-31
Completion:: 2029-03-31

Conditions

Febrile Urinary Tract Infection

Interventions

DRUG

No Results Yet

NCT07235228 | RECRUITING | NA

20 participants

Effects of Vivatlac Synbiotic on Gut Micribiota of IBS Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-11-21
Completion:: 2026-12-31

Conditions

Irritable Bowel Syndrome

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07231848 | COMPLETED | NA

48 participants

Bioavailability of Four Mitopure Formulations

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-11-03
Completion:: 2025-11-28

Conditions

Healthy Adults

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07227792 | RECRUITING | NA

35 participants

Tongue-out Radiation Therapy (TORT) for the Mitigation of Radiotherapy-related Toxicities in Patients With Head and Neck Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-11-23
Completion:: 2027-11-30

Conditions

Head and Neck Carcinoma

Interventions

RADIATION

No Results Yet

NCT07222072 | RECRUITING | PHASE4

120 participants

Methadone to Reduce Chronic Opioid Use After Major Spine Surgery: The MEND Pilot Feasibility Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-11-15
Completion:: 2027-10-31

Conditions

Post Operative Pain
Spinal Surgery

Interventions

DRUG

No Results Yet

NCT07222020 | RECRUITING | PHASE1

24 participants

Phase 1 Study of Intravaginal KB15A

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2026-01-01
Completion:: 2026-09-01

Conditions

Healthy Subjects

Interventions

DRUG

No Results Yet

NCT07214740 | COMPLETED | PHASE3

44 participants

Study to Evaluate a Pegcetacoplan (Syfovre®) Prefilled Syringe

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-10-24
Completion:: 2025-12-12

Conditions

Geographic Atrophy Secondary to Age-related Macular Degeneration

Interventions

DRUG

No Results Yet

NCT07213570 | RECRUITING | PHASE2

60 participants

STREAM-2: Second-line Treatment With REgorafenib in Advanced RAS-Mutant Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-10-16
Completion:: 2026-10-31

Conditions

Colorectal Cancer Metastatic

Interventions

DRUG

No Results Yet

NCT07210424 | NOT_YET_RECRUITING

132 participants

Comparative Study on the Post-operative Pain and Other Outcomes of Mesh Fixation With Prolene vs Vicryl vs Skin Staples in Lichtenstein Inguinal Hernia Repair.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-12-29
Completion:: 2026-01-29

Conditions

Inguinal Hernia

Interventions

PROCEDURE

No Results Yet

NCT07209358 | RECRUITING | NA

298 participants

EDX110 Randomized Control Trial for Treatment of DFUs

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-10-30
Completion:: 2026-12-01

Conditions

Wound Heal
Diabetic Foot Ulcer

Interventions

DEVICE

No Results Yet

NCT07208019 | RECRUITING | NA

340 participants

Electroacupuncture Treatment for Post-stroke Cognitive Impairment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-10-05
Completion:: 2026-12-30

Conditions

Post-Stroke Cognitive Impairment (PSCI)

Interventions

OTHER

No Results Yet

NCT07206407 | RECRUITING | NA

24 participants

Clinical Trial on Rapid Immune Modulating Effects

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-09-28
Completion:: 2026-02-01

Conditions

Immune Surveillance

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07198529 | RECRUITING | NA

130 participants

OCT-Guided Stent Optimization for Short-Duration Dual Antiplatelet Therapy in Stable Angina

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-09-30
Completion:: 2029-09-30

Conditions

Stable Angina
Coronary Artery Disease

Interventions

DRUG
DEVICE

No Results Yet

NCT07192913 | NOT_YET_RECRUITING | PHASE2

20 participants

Glymphatic Function TMS Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2026-01-31
Completion:: 2026-07-31

Conditions

Mild Cognitive Impairment

Interventions

DEVICE

No Results Yet

NCT07190456 | RECRUITING | NA

21 participants

Kinesiophobia vs. Task-Specific Fear: Defining Movement-Related Fear in ACL Reconstruction Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2026-01-01
Completion:: 2026-12-01

Conditions

ACL Reconstruction

Interventions

OTHER

No Results Yet

NCT07182162 | NOT_YET_RECRUITING | NA

100 participants

Point-of-Care Ultrasound (PoCUS) Teleeducation Curriculum for Hospital-at-home Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2026-04-01
Completion:: 2027-10-30

Conditions

Educational Problems

Interventions

OTHER

No Results Yet

NCT07181577 | RECRUITING | NA

672 participants

Sleep and Blankets

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-10-15
Completion:: 2026-12-15

Conditions

Sleep Problems
Insomnia

Interventions

DEVICE

No Results Yet

NCT07175493 | RECRUITING | PHASE1/PHASE2

158 participants

A Study of CM336 in Patients With Relapsed or Refractory Autoimmune Cytopenia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-11-18
Completion:: 2027-11-18

Conditions

Autoimmune Cytopenia
Immune Thrombocytopenia (ITP)
Autoimmune Hemolytic Anemia
Evans Syndrome

Interventions

BIOLOGICAL

No Results Yet

NCT07169552 | RECRUITING | PHASE2

50 participants

HC010 in First-line PD-L1 Positive Advanced NSCLC Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-12-09
Completion:: 2026-12-30

Conditions

NSCLC

Interventions

DRUG

No Results Yet

NCT07167238 | NOT_YET_RECRUITING | NA

42 participants

The Effect of Video Game-Based Exercise Training in Patients With Interstitial Lung Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2026-01-25
Completion:: 2026-09-25

Conditions

Interstitial Lung Disease

Interventions

BEHAVIORAL

No Results Yet

NCT07155876 | ENROLLING_BY_INVITATION | NA

128 participants

Exploring the Effect of Aromatherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-10-15
Completion:: 2026-09-01

Conditions

Anxiety
Labor Pain
Nausea and Vomiting

Interventions

OTHER

No Results Yet

NCT07150715 | RECRUITING | PHASE2

107 participants

Alpha-Emitting Radionuclide or Beta-Emitting Radionuclide With Metastasis-Directed Stereotactic Body Radiotherapy for the Treatment of Recurrent, Oligometastatic Prostate Adenocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-12-12
Completion:: 2030-10-31

Conditions

Oligometastatic Prostate Adenocarcinoma
Recurrent Prostate Adenocarcinoma

Interventions

DRUG
PROCEDURE
OTHER
RADIATION

No Results Yet

NCT07148986 | COMPLETED | NA

500 participants

Radicle Clarity: A Study Assessing the Impact of Health and Wellness Products on Cognitive Function and Related Health Outcomes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-08-21
Completion:: 2025-11-14

Conditions

Cognitive Function

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07144839 | RECRUITING

640 participants

Placental Risk Assessment to CusTomize Individualized Pregnancy Care and Evaluation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-09-18
Completion:: 2029-06-30

Conditions

Stillbirth
Placental Insufficiency

Interventions

OTHER

No Results Yet

NCT07141160 | ENROLLING_BY_INVITATION | NA

255 participants

ADL+2.0: Intervention for Prevention of Cognitive Decline in Community-dwelling Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-05-08
Completion:: 2029-08-30

Conditions

Cognitive Decline

Interventions

OTHER

No Results Yet

NCT07131709 | COMPLETED | NA

191 participants

Patient Satisfaction With AI Scribes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-08-11
Completion:: 2025-10-21

Conditions

AI (Artificial Intelligence)
Patient Satisfaction With AI in Doctors Consultations

Interventions

OTHER

No Results Yet

NCT07122713 | RECRUITING | NA

30 participants

Definitive Radiation Therapy for Inoperable Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-12-08
Completion:: 2028-12-30

Conditions

Breast Cancer
Breast Adenocarcinoma

Interventions

RADIATION

No Results Yet

NCT07117994 | COMPLETED | NA

500 participants

Radicle Revive 24: A Study of Health and Wellness Products on Hormonal Health and Associated Health Outcomes in Women With Peri-Menopausal Health Issues

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-08-05
Completion:: 2025-11-12

Conditions

Stress
Menopause
Fatigue
Sleep

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07107009 | NOT_YET_RECRUITING

1906 participants

ClimAIr: AI to Assess the Impact of Pollution and Climate on Respiratory Health in Europe

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2026-01-31
Completion:: 2026-06-30

Conditions

Allergic Rhinitis
Asthma

No Results Yet

NCT07097545 | RECRUITING | NA

300 participants

Change in Social Media Use and Well-being Among College Students Receiving a Two-week Exercise or Mindfulness Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-08-24
Completion:: 2026-12-31

Conditions

Social Media Addiction
Anxiety
Depression Disorder
Wellbeing

Interventions

BEHAVIORAL

No Results Yet

NCT07079241 | RECRUITING | NA

1000 participants

A Model to Save Lives Through a Volunteer First Responder Service Providing Antidote Treatment in Opioid Overdose

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-09-01
Completion:: 2027-08-31

Conditions

Opioid Overdose

Interventions

OTHER

No Results Yet

NCT07075159 | RECRUITING | NA

20 participants

Hydrocolloid Dressings for Oculofacial Plastic and Reconstructive Wound Healing

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-02-28
Completion:: 2026-09-01

Conditions

Wound Healing
Mohs Micrographic Surgery
Oculofacial Reconstruction

Interventions

DEVICE

No Results Yet

NCT07073391 | NOT_YET_RECRUITING

100 participants

Clinical Study of How Information Flows Across the Human Cortical Sheet Layers (Laminae), Aiming to Discover Key Principles of Laminar Circuits and Information Flow for Complex Behavior.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2026-09-01
Completion:: 2030-09-01

Conditions

Neuronal Mechanisms
Laminar Circuits

Interventions

DEVICE

No Results Yet

NCT07062627 | RECRUITING | PHASE2

12 participants

Anbalcabtagene Autoleucel in Relapsed/Refractory CNS Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-11-12
Completion:: 2026-12-31

Conditions

Primary CNS Lymphoma (PCNSL)
Diffuse Large B Cell Lymphoma (DLBCL)

Interventions

GENETIC

No Results Yet

NCT07059013 | RECRUITING | NA

130 participants

A Chatbot-based Program to Promote Well-being in Caregivers of Children With Autism Spectrum Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-08-15
Completion:: 2026-05-31

Conditions

Autism Spectrum Disorder

Interventions

DEVICE

No Results Yet

NCT07056816 | COMPLETED | NA

72 participants

Effects of Interactive Toys and Robots on Anxiety and Fear in Children Receiving Nebulized Inhalation in the Pediatric Emergency Department

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-06-30
Completion:: 2025-07-01

Conditions

Child
Fear Anxiety
Inhalant Use

Interventions

OTHER

No Results Yet

NCT07055503 | ENROLLING_BY_INVITATION

30 participants

Use of the Hemanext One® Hypoxic Red Blood Cell Storage System for Transfusion in Thalassemia Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-11-20
Completion:: 2026-07-31

Conditions

Transfusion-dependent Beta-Thalassemia
Blood Transfusion

No Results Yet

NCT07050992 | ACTIVE_NOT_RECRUITING | NA

120 participants

Laser Posterior Nasal Nerve Neurolysis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-11-01
Completion:: 2025-12-06

Conditions

Rhinorrhea
Sneezing
Allergic Rhinitis
Chronic Rhinitis
Nasal Obstruction
Nasal Congestion
Nasal Allergies
Nasal Stuffiness

Interventions

PROCEDURE

No Results Yet

NCT07044518 | COMPLETED | NA

21 participants

The Clinical Application of Apple AirPods Pro 2 vs. Hearing Aids

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-09-11
Completion:: 2025-12-04

Conditions

Hearing Loss

Interventions

DEVICE

No Results Yet

NCT07040566 | RECRUITING | PHASE2

326 participants

A Trial of Varenicline for E-cigarette Cessation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-10-14
Completion:: 2030-07-30

Conditions

E-cigarette Use
Vaping
Nicotine Dependence

Interventions

DRUG

No Results Yet