Clinical Trials Updated in 2025

NCT06714357 | RECRUITING | PHASE2

130 participants

ValproIc Acid to Potentiate Anti-EGFR Treatment Efficacy and Prevent/Revert Resistance in Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-03-12
Completion:: 2026-12-20

Conditions

Colorectal Cancer Metastatic

Interventions

DRUG

No Results Yet

NCT06712589 | ACTIVE_NOT_RECRUITING

2000 participants

The Image Characteristics of Adult Appendix on Computed Tomography

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-11-01
Completion:: 2026-12-31

Conditions

Location of Appendix

No Results Yet

NCT06704529 | COMPLETED

98 participants

Cortical Processing of Proprioception Related to Pitching Performance in Baseball Players With Glenohumeral Internal Rotation Deficit

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-08-20
Completion:: 2025-05-30

Conditions

Glenohumeral Internal Rotation Deficit

Interventions

BEHAVIORAL

No Results Yet

NCT06695637 | WITHDRAWN | EARLY_PHASE1

0 participants

Individualized Neuromodulation of Craving Control for Meth Use Disorders

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-09-01
Completion:: 2029-09-01

Conditions

Substance Use Disorders
Methamphetamine Use Disorders

Interventions

RADIATION

No Results Yet

NCT06682572 | ACTIVE_NOT_RECRUITING | PHASE2

16 participants

A Study of Avutometinib + Defactinib in Recurrent Low-Grade Serous Ovarian Cancer in Japanese Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-10-30
Completion:: 2025-12-31

Conditions

Low Grade Serous Ovarian Cancer
Ovarian Cancer

Interventions

DRUG

No Results Yet

NCT06682403 | COMPLETED | NA

49 participants

Distribution and Randomization of Gun Safety Devices to Measure Uptake and Preferences

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-06-01
Completion:: 2024-10-01

Conditions

Gun Violence Prevention

Interventions

BEHAVIORAL

Results Available

NCT06648759 | RECRUITING | NA

60 participants

Vagal Stimulator to Reduce Nasogastric Tube Use

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-12-04
Completion:: 2026-09-30

Conditions

Nasogastric Tube Intubation

Interventions

DEVICE

No Results Yet

NCT06631482 | ACTIVE_NOT_RECRUITING | NA

100 participants

Comparison Bewteen Intraoperative HPI vs. High Mean Arterial Pressure Threshold

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-09-16
Completion:: 2025-10-14

Conditions

Hypotension During Surgery

Interventions

DEVICE
DRUG

No Results Yet

NCT06627894 | RECRUITING | NA

300 participants

Attenuating DEPression With Internet CBT to Slow Cognitive Decline in Older ICU Survivors(ADEPT-ICU)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-03-13
Completion:: 2029-10-30

Conditions

Depression
Cognitive Decline

Interventions

BEHAVIORAL

No Results Yet

NCT06608498 | COMPLETED | NA

50 participants

DMHI for At-Risk College Students

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-10-04
Completion:: 2025-01-06

Conditions

Prodromal Symptoms
Psychosis

Interventions

BEHAVIORAL

No Results Yet

NCT06579521 | COMPLETED | NA

92 participants

Real-world Experiences of Alcohol and Cognitions Over Time

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-08-18
Completion:: 2025-08-31

Conditions

Alcohol Intoxication

Interventions

OTHER

No Results Yet

NCT06579118 | COMPLETED | NA

120 participants

The Impact of Laughter Yoga on Symptom Management and Quality of Life in Postmenopausal Women

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-08-25
Completion:: 2023-12-15

Conditions

Menopause

Interventions

OTHER

No Results Yet

NCT06561204 | COMPLETED | NA

94 participants

Full-mouth Electronic Toothbrush vs. Conventional Electronic Toothbrush

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-12-30
Completion:: 2025-10-10

Conditions

Toothbrush
Gingivitis
Plaque

Interventions

DEVICE

No Results Yet

NCT06550115 | RECRUITING | NA

50 participants

Impact of Circulating and Tissue-specific Lipids on Vascular Function and Insulin Sensitivity in Chronic Night Shift Workers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-03-01
Completion:: 2028-06-30

Conditions

Circadian Rhythm Sleep Disorder of Shift Work Type
Metabolic Disease
Insulin Sensitivity
Blood Pressure

Interventions

BEHAVIORAL

No Results Yet

NCT06541249 | RECRUITING | PHASE2

54 participants

MethoTRExATE in MyelOpRolifErative Neoplasms (TREATMORE) Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-10-02
Completion:: 2027-06-30

Conditions

Polycythemia Vera (PV)
Essential Thrombocythemia (ET)
Myelofibrosis (MF)

Interventions

DRUG

No Results Yet

NCT06519058 | COMPLETED | NA

36 participants

Effectiveness of Self-Myofascial Stretching on Carpal Tunnel Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-12-01
Completion:: 2024-02-04

Conditions

Patients With Stage I and II Carpal Tunnel Syndrome

Interventions

OTHER

No Results Yet

NCT06486090 | COMPLETED | NA

2954 participants

Effectiveness and Process Evaluation of the Injury-preventive Program #Utviklingsklar

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-05-07
Completion:: 2025-11-09

Conditions

Sports Injury

Interventions

BEHAVIORAL

No Results Yet

NCT06475677 | COMPLETED | NA

23 participants

OrthoCor Advanced Trial for Knee Osteoarthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-06-18
Completion:: 2025-10-06

Conditions

Osteoarthritis, Knee
Osteo Arthritis Knee

Interventions

DEVICE

No Results Yet

NCT06472336 | RECRUITING | NA

498 participants

IntraCranial Atherosclerosis Related Large-vessel Occlusion Treated With Urgent Stenting (ICARUS)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-03-31
Completion:: 2027-08-31

Conditions

Stroke
Stroke, Acute Ischemic
Intracranial Atherosclerosis

Interventions

PROCEDURE

No Results Yet

NCT06461338 | ACTIVE_NOT_RECRUITING | NA

60 participants

Acupuncture for Enhancing Immunotherapy in Advanced NSCLC：a Pilot Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-08-15
Completion:: 2026-07-31

Conditions

Non-small Cell Lung Cancer
Non-Small-Cell Lung Carcinoma

Interventions

PROCEDURE

No Results Yet

NCT06456190 | COMPLETED | NA

50 participants

Testing STAR and TexSTAR: A Video and Text Messaging Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-03-12
Completion:: 2025-12-03

Conditions

Sexual Violence
Posttraumatic Stress Disorder
Opioid Use
Opioid Misuse

Interventions

BEHAVIORAL

No Results Yet

NCT06450561 | COMPLETED

129 participants

Adherence to Secondary Prevention Guidelines for Cardiovascular Risk

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-03-01
Completion:: 2025-09-30

Conditions

Atherosclerosis
Stroke, Ischemic
Acute Coronary Syndrome
Ischemic Heart Disease
Peripheral Arterial Disease

Interventions

OTHER

No Results Yet

NCT06449716 | COMPLETED | NA

80 participants

Tailored Versus Traditional Resistance Exercise

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-05-20
Completion:: 2025-12-04

Conditions

Exercise Training

Interventions

OTHER

No Results Yet

NCT06448715 | COMPLETED

11 participants

Real-World Treatment Study of Soliris (Eculizumab)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-05-28
Completion:: 2025-01-03

Conditions

Observational

No Results Yet

NCT06430788 | RECRUITING | PHASE2

35 participants

A Study of Emapalumab for Pediatric Aplastic Anemia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-05-21
Completion:: 2029-05-21

Conditions

Aplastic Anemia
Cytopenia
Hypocellular Marrow

Interventions

BIOLOGICAL

No Results Yet

NCT06397651 | ACTIVE_NOT_RECRUITING | NA

146 participants

A Randomised Controlled Trial to Evaluate the Impact of Complement Theory's Live CoActive Exercise Coaching and Personalized Digital Application on Cancer Survivors' Quality of Life

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-05-12
Completion:: 2026-02-28

Conditions

Breast Cancer
Lung Cancer
Prostate Cancer
Colorectal Cancer
Other Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06389266 | COMPLETED | NA

90 participants

Network-Targeted Neuromodulation for Nicotine Dependence in Schizophrenia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-06-15
Completion:: 2025-09-15

Conditions

Schizophrenia
Nicotine Dependence

Interventions

DEVICE

No Results Yet

NCT06387121 | RECRUITING | PHASE2

53 participants

Efficacy and Safety of Low-dose Chemotherapy Plus Immuno-targeted Drugs in Newly Diagnosed Adult Ph- B-ALL

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-04-02
Completion:: 2026-12-01

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma

Interventions

DRUG

No Results Yet

NCT06370455 | COMPLETED | NA

30 participants

Comparison of Septal Advancement Flap and Columellar Strut Effect on Nasal Tip

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-01-23
Completion:: 2025-08-23

Conditions

Rhinoplasty

Interventions

PROCEDURE

No Results Yet

NCT06367556 | RECRUITING | NA

306 participants

Emotion and Symptom-Focused Engagement (EASE) for Caregivers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-02-14
Completion:: 2027-10-01

Conditions

Trauma and Stressor Related Disorders
Pediatric Cancer
Caregiver Burden

Interventions

BEHAVIORAL

No Results Yet

NCT06358157 | ACTIVE_NOT_RECRUITING | NA

30 participants

The Ladera Large Bore Closure Feasibility Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-10-21
Completion:: 2025-12-31

Conditions

Vascular Closure
Femoral Arteriotomy Closure

Interventions

DEVICE

No Results Yet

NCT06354491 | ACTIVE_NOT_RECRUITING | NA

24 participants

An Imaging-based Quantitative Biomarker Assay for NAFLD in Children

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-04-01
Completion:: 2025-06-20

Conditions

NAFLD
NASH

Interventions

DEVICE

No Results Yet

NCT06336356 | COMPLETED | PHASE2

48 participants

A Study to Evaluate Cortisol Reserve in Response to Adrenocorticotropic Hormone (ACTH) Stimulation Test Following Baxdrostat Treatment Compared to Placebo in Participants With Uncontrolled Hypertension

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-06-10
Completion:: 2024-12-04

Conditions

Uncontrolled Hypertension

Interventions

DRUG

Results Available

NCT06333834 | COMPLETED | PHASE2/PHASE3

56 participants

Assessment of the Efficacy of Scorpion Antivenom Therapy in a Dose-response Manner, in Patients With Scorpionism

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-06-15
Completion:: 2025-11-01

Conditions

Centruroides Envenomation

Interventions

DRUG

No Results Yet

NCT06330181 | RECRUITING | NA

48 participants

Virtual Walking Therapy for Neuropathic Pain Following Incomplete Spinal Cord Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-12-02
Completion:: 2026-01-31

Conditions

Spinal Cord Injuries
Neuropathic Pain

Interventions

OTHER

No Results Yet

NCT06329544 | RECRUITING | NA

30 participants

High Fructose Diet, the Gut Microbiome, and Metabolic Health

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-10-08
Completion:: 2028-08-31

Conditions

MASLD
Type 2 Diabetes
Obesity

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06311591 | ENROLLING_BY_INVITATION | NA

27908 participants

Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part B

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-11-07
Completion:: 2027-06-01

Conditions

Suicidal Ideation
Suicide Attempt
Self Harm

Interventions

DEVICE

No Results Yet

NCT06308874 | COMPLETED | PHASE1

16 participants

Investigate Safety, Tolerability, PK/PD of J2H-1702 in Healthy Females

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-01-02
Completion:: 2023-02-17

Conditions

Non-alcoholic Steatohepatitis

Interventions

DRUG

No Results Yet

NCT06308861 | COMPLETED | PHASE1

100 participants

Investigate Safety, Tolerability, PK/PK of J2H 1702 in Healthy Males

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2020-08-12
Completion:: 2021-06-25

Conditions

Non-alcoholic Steatohepatitis

Interventions

DRUG

No Results Yet

NCT06298396 | COMPLETED | NA

20 participants

Investigating Stimulation Parameter and Electrode Mode Changes on Speech Perception in Experienced Adult Cochlear Implant Recipients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-05-27
Completion:: 2024-12-16

Conditions

Hearing Loss, Sensorineural

Interventions

DEVICE

Results Available