Clinical Trials

NCT05603728 | RECRUITING

20000 participants

Exactech Shoulder Post Market Clinical Follow-up Study

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-15

Start Date:

2007-07-19

Completion:

2030-12-31

Conditions

• Osteo Arthritis Shoulders
• Osteonecrosis
• Rotator Cuff Tears
• Rotator Cuff Tear Arthropathy
• Ankylosing Spondylitis
• Post-traumatic Osteoarthritis
• Rheumatoid Arthritis
• Fracture
• Infections

No Results Yet

NCT05592782 | WITHDRAWN | NA

0 participants

VR Mindfulness Study

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2022-10-31

Completion:

2023-10-31

Conditions

• Anxiety
• Depression
• Stress
• Pain, Acute
• Pain, Chronic

Interventions

• BEHAVIORAL

No Results Yet

NCT05590455 | RECRUITING | PHASE2

130 participants

Tnf Inhibitors to Reduce Mortality in HIV-1 Infected PAtients With Tuberculosis meNIngitis

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2023-04-11

Completion:

2027-06-30

Conditions

• Tuberculous Meningitis
• HIV I Infection

Interventions

• DRUG

No Results Yet

NCT05561361 | RECRUITING

200 participants

The Effect of SAAE on Vascular Endothelial Function in PA Patients

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-15

Start Date:

2022-10-01

Completion:

2026-11-30

Conditions

• Primary Aldosteronism

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05555355 | COMPLETED | PHASE4

104 participants

Prevena Spine for Use in Spine Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2022-12-01

Completion:

2025-11-01

Conditions

• Surgery
• Incision, Surgical

Interventions

• DEVICE
• PROCEDURE

No Results Yet

NCT05520281 | COMPLETED | NA

24 participants

Short-term Psychodynamic Psychotherapy in Serious Physical Illness

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2022-09-15

Completion:

2025-08-06

Conditions

• Malignant Neoplasm
• Carcinoma
• Palliative Care

Interventions

• BEHAVIORAL

No Results Yet

NCT05512819 | COMPLETED | PHASE3

541 participants

A Study to Describe the Safety and Immunogenicity of 20vPnC in Infants in India and Taiwan

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2022-09-16

Completion:

2025-09-20

Conditions

• Pneumococcal Disease

Interventions

• BIOLOGICAL

No Results Yet

NCT05505851 | COMPLETED | NA

40 participants

Sequential Core Stability Corrective Exercise Approach in Lower Crossed Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2024-02-10

Completion:

2025-12-01

Conditions

• Low Back Pain

Interventions

• OTHER

No Results Yet

NCT05493280 | COMPLETED | NA

15 participants

Fractionated 1927nm Laser for Hyperpigmentation in Fitzpatrick Skin Phototypes V and VI

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2022-11-14

Completion:

2024-07-26

Conditions

• Hyperpigmentation

Interventions

• DEVICE

Results Available

NCT05454358 | TERMINATED | PHASE2/PHASE3

12 participants

Letrozole as Maintenance Therapy for Post-surgical Endometrial Cancer Patients With NSMP

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2022-08-02

Completion:

2025-12-01

Conditions

• Endometrial Cancer

Interventions

• DRUG

No Results Yet

NCT05431972 | COMPLETED | NA

257 participants

Cardea SOLOTM for Paroxysmal Atrial Fibrillation Diagnosis in ESUS Patients With Left Atrial Enlargement

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2022-11-01

Completion:

2024-09-13

Conditions

• Embolic Stroke of Undetermined Source

Interventions

• DEVICE

No Results Yet

NCT05421676 | RECRUITING | NA

10 participants

Fetal Endoscopic Tracheal Occlusion for CDH (CDH)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2024-02-12

Completion:

2027-12-31

Conditions

• Congenital Diaphragmatic Hernia

Interventions

• DEVICE

No Results Yet

NCT05410418 | ACTIVE_NOT_RECRUITING | PHASE2

34 participants

Mosunetuzumab and Polatuzumab Vedotin for Untreated Follicular Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2022-10-24

Completion:

2025-09-18

Conditions

• Lymphoma, Follicular
• Follicular Lymphoma

Interventions

• DRUG

No Results Yet

NCT05374525 | COMPLETED | PHASE4

287 participants

A Study Evaluating Implementation Strategies for the Delivery of Cabotegravir in Low and High-Volume PrEP Site in the United States

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2022-05-18

Completion:

2024-08-08

Conditions

• HIV Infections

Interventions

• DRUG

Results Available

NCT05335434 | RECRUITING | NA

20 participants

Intraoral Photobiomodulation Therapy to Prevent Oral Mucositis in Patients Undergoing Hematopoietic Cell Transplantation

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2022-06-10

Completion:

2026-06-20

Conditions

• Myeloablative Allogeneic Hematopoietic Cell Transplantation
• Intraoral Photobiomodulation Therapy
• Oral Mucositis
• Mucosal Ulcer

Interventions

• DEVICE

No Results Yet

NCT05317936 | TERMINATED | PHASE1/PHASE2

3 participants

Pirtobrutinib (LOXO-305) Consolidation for MRD Eradication in Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL) Treated With Venetoclax

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2022-11-16

Completion:

2025-10-06

Conditions

• Chronic Lymphocytic Leukemia
• Small Lymphocytic Lymphoma

Interventions

• DRUG

No Results Yet

NCT05301361 | ENROLLING_BY_INVITATION | PHASE1

68 participants

Sensitivity of the NIH Toolbox to Stimulant Treatment in Intellectual Disabilities

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2023-02-01

Completion:

2026-09-29

Conditions

• Intellectual Disability
• Fragile X Syndrome
• Down Syndrome
• Attention Deficit Hyperactivity Disorder

Interventions

• DRUG

No Results Yet

NCT05172024 | COMPLETED

15172 participants

Understanding the Long-term Impact of COVID-19 in Adults (RECOVER)

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-15

Start Date:

2021-10-29

Completion:

2025-10-31

Conditions

• SARS-CoV2 Infection

No Results Yet

NCT05159700 | ACTIVE_NOT_RECRUITING | PHASE1

39 participants

A Phase I Study, Evaluating the Safety, Pharmacokinetics and Efficacy of PRJ1-3024 in Subjects With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2022-03-31

Completion:

2024-07-17

Conditions

• Advanced Solid Tumor
• Advanced Solid Malignancies

Interventions

• DRUG

No Results Yet

NCT05158894 | RECRUITING

1884 participants

Observational Study to Assess Adverse Events When Adult Female Participants Are Treated With Ubrelvy (Ubrogepant) or Qulipta (Atogepant) During Pregnancy

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-15

Start Date:

2023-01-10

Completion:

2036-01-31

Conditions

• Migraine

No Results Yet

NCT05152927 | COMPLETED | NA

79 participants

Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Parathyroidectomy

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2022-01-10

Completion:

2024-11-30

Conditions

• Parathyroid Diseases
• Parathyroid Dysfunction
• Parathyroid Neoplasms
• Parathyroid Adenoma
• Hypercalcemia
• Neoplasms, Glandular and Epithelial
• Endocrine Gland Neoplasms
• Adenoma
• Hyperparathyroidism
• Hyperparathyroidism, Primary

Interventions

• DEVICE

Results Available

NCT05128734 | NOT_YET_RECRUITING | PHASE2

40 participants

Temozolomide Monotherapy or in Combination With Olaparib in Patients With Triple Negative Breast Cancer (TNBC)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2026-04-01

Completion:

2028-04-01

Conditions

• Breast Cancer Triple Negative

Interventions

• DRUG

No Results Yet

NCT05111288 | RECRUITING | NA

120 participants

Influence of Pulse Electromagnetic Field Therapy on Myocardial Ischemia

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2022-05-18

Completion:

2026-08-31

Conditions

• Coronary Artery Disease
• Myocardial Infarction

Interventions

• DEVICE

No Results Yet

NCT05095727 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

15 participants

A Study of mRNA-3745 in Adult and Pediatric Participants With Glycogen Storage Disease Type 1a (GSD1a)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2022-06-01

Completion:

2026-11-30

Conditions

• Glycogen Storage Disease

Interventions

• DRUG

No Results Yet

NCT05091034 | ACTIVE_NOT_RECRUITING | NA

374 participants

CAMP Air: Efficacy and Cost-effectiveness in Urban Adolescents

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2021-11-08

Completion:

2026-06-30

Conditions

• Asthma

Interventions

• BEHAVIORAL

No Results Yet

NCT05085366 | TERMINATED | PHASE3

7454 participants

A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Healthy Participants 16 to 40 Years of Age

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2021-10-26

Completion:

2025-11-04

Conditions

• Cytomegalovirus Infection

Interventions

• BIOLOGICAL

No Results Yet

NCT05084248 | COMPLETED | PHASE4

48 participants

Vitamin D Deficiency in Adults Following a Major Burn Injury

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2022-09-29

Completion:

2025-08-18

Conditions

• Vitamin D Deficiency
• Burns

Interventions

• DRUG

No Results Yet

NCT05077748 | COMPLETED

202 participants

An 18-year Follow-up Study on OSA in a Population-based Cohort

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-15

Start Date:

2021-10-20

Completion:

2025-09-30

Conditions

• Epidemiology
• Natural History
• Obstructive Sleep Apnea
• Cardiovascular Complication
• Neurocognitive Dysfunction

Interventions

• OTHER

No Results Yet

NCT05040360 | RECRUITING | PHASE2

141 participants

Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2022-05-05

Completion:

2027-03-31

Conditions

• Metastatic Malignant Neoplasm in the Liver
• Pancreatic Neuroendocrine Tumor
• Stage I Pancreatic Neuroendocrine Tumor AJCC v8
• Stage II Pancreatic Neuroendocrine Tumor AJCC v8
• Stage III Pancreatic Neuroendocrine Tumor AJCC v8

Interventions

• DRUG

No Results Yet

NCT04982419 | RECRUITING | PHASE2/PHASE3

240 participants

Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2021-11-01

Completion:

2028-03-31

Conditions

• Acute Kidney Injury
• Heart Failure
• Contrast Induced Nephropathy
• Coronary Angiography
• Percutaneous Coronary Intervention

Interventions

• DEVICE

No Results Yet

NCT04965064 | RECRUITING | PHASE2

22 participants

Trial of Neratinib Plus Capecitabine in Subjects With HER2-Negative Metastatic Breast Cancer With Brain Metastases and Abnormally Active HER2 Signaling

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2022-09-23

Completion:

2026-09-01

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04948203 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

60 participants

Assessing the Efficacy of Sirolimus in Patients With COVID-19 Pneumonia for Prevention of Post-COVID Fibrosis

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2021-07-09

Completion:

2026-12-31

Conditions

• Pulmonary Fibrosis
• COVID-19 Pneumonia
• Long COVID

Interventions

• DRUG

No Results Yet

NCT04909203 | COMPLETED | NA

56 participants

iKinnect2.0 for Juvenile Justice Involved Youth at Risk for Suicide

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2023-06-01

Completion:

2025-10-21

Conditions

• Child Behavior Disorders
• Suicide and Self-harm

Interventions

• DEVICE

No Results Yet

NCT04906460 | RECRUITING | PHASE1/PHASE2

26 participants

Open-label Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy (FORWARD-53)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2021-09-28

Completion:

2026-06-27

Conditions

• Duchenne Muscular Dystrophy

Interventions

• DRUG

No Results Yet

NCT04884412 | COMPLETED | NA

128 participants

Deep Brain Stimulation for Parkinson's Disease: Probabilistic STN Targeting Under General Anaesthesia Without Micro-electrode Recordings vs Current Targeting Procedure

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2021-11-10

Completion:

2025-11-18

Conditions

• Parkinson Disease

Interventions

• PROCEDURE

No Results Yet

NCT04830059 | COMPLETED | NA

93 participants

The Joint Effect of Air Pollution and Exercise on Cognitive Function

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2020-11-01

Completion:

2021-10-30

Conditions

• Exercise
• Air Pollution
• Cognition
• Health Promotion

Interventions

• BEHAVIORAL

No Results Yet

NCT04810689 | TERMINATED | PHASE2

10 participants

Pilot Trial of XFBD, a TCM, in Persons With COVID-19

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2021-03-01

Completion:

2022-06-20

Conditions

• Covid19

Interventions

• DRUG
• OTHER

Results Available

NCT04770532 | COMPLETED | PHASE3

526 participants

A Research Study to Compare Two Types of Insulin, a New Weekly Insulin, Insulin Icodec and an Available Daily Insulin, Insulin Degludec, in People With Type 2 Diabetes Who Use Daily Insulin

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2021-03-05

Completion:

2022-01-27

Conditions

• Diabetes Mellitus, Type 2

Interventions

• DRUG

Results Available

NCT04738474 | COMPLETED | NA

78 participants

Assessing and Promoting Resilience in Patients With Adult Congenital Heart Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-15

Start Date:

2023-03-15

Completion:

2024-07-25

Conditions

• Congenital Heart Disease

Interventions

• BEHAVIORAL
• OTHER

Results Available

NCT04703179 | ENROLLING_BY_INVITATION

5000 participants

Rare and Undiagnosed Disease Research Biorepository

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-15

Start Date:

2020-11-20

Completion:

2026-11-30

Conditions

• Undiagnosed Disease
• Rare Diseases

Interventions

• OTHER

No Results Yet