Clinical Trials Updated in 2025

NCT06606457 | COMPLETED | NA

20 participants

PACE CF, a 3-session Mind-body Pain Management Program for Adults With Cystic Fibrosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-09-10
Completion:: 2025-04-09

Conditions

Cystic Fibrosis (CF)
Pain Management

Interventions

BEHAVIORAL

No Results Yet

NCT06606028 | RECRUITING

250 participants

Tumor-Informed ctDNA Testing for MRD Following Treatment of Squamous Cell Carcinoma

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-10-09
Completion:: 2028-12-30

Conditions

Squamous Cell Carcinoma of Head and Neck
Squamous Cell Carcinoma Head and Neck Cancer (HNSCC)
Squamous Cell Carcinoma of Skin
Cutaneous Squamous Cell Carcinoma (CSCC)

Interventions

PROCEDURE
OTHER

No Results Yet

NCT06593340 | NOT_YET_RECRUITING | NA

112 participants

Evaluation of Report-Back Strategies for Long-term and Short-term Exposure Information in Rural Tribal Populations

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2026-10-31
Completion:: 2028-04-30

Conditions

Behavior Change

Interventions

BEHAVIORAL

No Results Yet

NCT06573502 | COMPLETED | NA

42 participants

Platelet Rich Plasma Combined With Platelet Rich Fibrin in Management of Temporomandibular Joint Osteoarthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2025-03-29
Completion:: 2025-09-29

Conditions

Osteoarthritis

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06555289 | RECRUITING

40 participants

Outcomes of Clareon PanOptix Pro in Patients With Prior Myopic Refractive Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-10-23
Completion:: 2026-09-01

Conditions

Cataract

Interventions

DEVICE

No Results Yet

NCT06551792 | COMPLETED

118 participants

The Effect of Magnesium Deficiency on Transforaminal Epidural Steroid Injection Success: An Observational Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-06-01
Completion:: 2024-08-30

Conditions

Pain, Back

Interventions

OTHER

No Results Yet

NCT06512922 | ENROLLING_BY_INVITATION | NA

120 participants

Adaptive Cognitive Training on Cognitive Function in Elderly Hypertension Patients in the Community

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-10-29
Completion:: 2026-09-30

Conditions

Hypertension
Condition
Aging

Interventions

DEVICE

No Results Yet

NCT06492538 | RECRUITING

300 participants

Biometric Changes After Intervention of Anterior Chamber Angle : an Observational Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-12-01
Completion:: 2025-12-30

Conditions

Angle-closure Glaucoma
Minimally Invasive Glaucoma Surgery
Goniosynechialysis
Goniotomy
Glaucoma

Interventions

PROCEDURE

No Results Yet

NCT06491836 | COMPLETED | NA

50 participants

Oligoantigenic Diet and Core Symptomatology of Children With Attention-Deficit /Hyperactivity Disorder (ADHD).

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-09-01
Completion:: 2025-10-01

Conditions

Attention Deficit Disorder

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT06489483 | RECRUITING | NA

50 participants

Action Regulation Behavioral

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-04-24
Completion:: 2026-11-30

Conditions

Parkinson Disease

Interventions

BEHAVIORAL

No Results Yet

NCT06480890 | COMPLETED

362 participants

Real-World Effectiveness of a Triple Combination BDP/FF/GB in a Single Pressurised Metered Dose Inhaler in COPD Patients (TRIPHY)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-07-02
Completion:: 2025-09-12

Conditions

Chronic Obstructive Pulmonary Disease

No Results Yet

NCT06465147 | RECRUITING | PHASE1

12 participants

REACT-01: Reversing Autoimmunity Through Cell Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-12-16
Completion:: 2028-10-31

Conditions

Systemic Lupus Erythematosus

Interventions

BIOLOGICAL

No Results Yet

NCT06438783 | TERMINATED | PHASE1

20 participants

TQB2928 Injection Combined Anlotinib Hydrochloride Capsule in Recurrent/Metastatic Osteosarcoma and Other Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-02-15
Completion:: 2025-06-18

Conditions

Osteosarcoma
Other Solid Tumors

Interventions

DRUG

No Results Yet

NCT06437639 | COMPLETED | PHASE4

80 participants

MEXIDOL® Sequential Therapy of Patients With Primary Open-angle Glaucoma (POAG)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-09-15
Completion:: 2023-11-29

Conditions

Primary Open-Angle Glaucoma (POAG)

Interventions

DRUG

No Results Yet

NCT06434961 | COMPLETED | PHASE3

498 participants

The Trial of SHR6508 in Secondary Hyperparathyroidism

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-06-14
Completion:: 2025-09-29

Conditions

Secondary Hyperparathyroidism

Interventions

DRUG

No Results Yet

NCT06424860 | RECRUITING | PHASE1

146 participants

Fish Oil, Metformin and Heart Health in PCOS

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2025-11-01
Completion:: 2026-12-30

Conditions

PCOS
Cardiovascular Disease
Atherosclerotic Cardiovascular Disease
Atherosclerotic Plaque
Cardiac Hypertrophy

Interventions

DIETARY_SUPPLEMENT
DRUG
COMBINATION_PRODUCT

No Results Yet

NCT06400745 | COMPLETED | NA

87 participants

Clareon PanOptix Pro vs. Clareon PanOptix - Study A

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-06-18
Completion:: 2024-12-13

Conditions

Aphakia
Presbyopia

Interventions

DEVICE
PROCEDURE

Results Available

NCT06353100 | COMPLETED

2365 participants

Chronic Pain in the General Population of Chile

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-01-01
Completion:: 2025-04-30

Conditions

Chronic Pain
Migraine Disability
Neuropathic Pain
Fibromyalgia
Depression, Anxiety
Self Harm
Insomnia
Loneliness

No Results Yet

NCT06336135 | COMPLETED

11 participants

Reduction in Symptoms After Laser Therapy With Acorn aHFS

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-03-25
Completion:: 2025-12-02

Conditions

Skin Aging

Interventions

OTHER

No Results Yet

NCT06335875 | COMPLETED | NA

15 participants

Brain Small Chain Fatty Acid Metabolism in Bipolar Disorder: Ketones

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-06-07
Completion:: 2025-08-20

Conditions

Bipolar Disorder

Interventions

DIETARY_SUPPLEMENT
BEHAVIORAL

No Results Yet

NCT06294288 | COMPLETED | PHASE1

60 participants

A Study of Single and Multiple Doses of LP-003 in Healthy Adult Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-07-13
Completion:: 2024-03-04

Conditions

Chronic Spontaneous Urticaria

Interventions

BIOLOGICAL

No Results Yet

NCT06287216 | RECRUITING | NA

200 participants

Preliminary Evaluation of a Mental Health Program: a Comparison Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-02-29
Completion:: 2026-04-30

Conditions

Mental Wellbeing

Interventions

BEHAVIORAL

No Results Yet

NCT06280755 | RECRUITING

7000 participants

Clinical Impact Through AI-assisted MS Care - A Retrospective Multi-center Observational Study.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-03-01
Completion:: 2027-04-30

Conditions

Multiple Sclerosis
NMO Spectrum Disorder
Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease
Radiologically Isolated Syndrome
Clinically Isolated Syndrome

No Results Yet

NCT06279871 | COMPLETED | PHASE3

1514 participants

Immunogenicity and Safety Study of Self-amplifying mRNA COVID-19 Vaccine Administered With Influenza Vaccines in Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-03-27
Completion:: 2024-10-09

Conditions

COVID-19

Interventions

BIOLOGICAL
OTHER

Results Available

NCT06228560 | COMPLETED | PHASE2

202 participants

Efficacy and Safety of LP-003 in Patients With CSU Who Remain Symptomatic Despite Antihistamine (H1) Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-01-26
Completion:: 2025-04-17

Conditions

Chronic Spontaneous Urticaria

Interventions

BIOLOGICAL

No Results Yet

NCT06200571 | ENROLLING_BY_INVITATION

200 participants

Biological Changes Associated With High Risk of Preeclampsia in Nulliparous Women

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-05-22
Completion:: 2026-12-31

Conditions

Preeclampsia

No Results Yet

NCT06200545 | COMPLETED | NA

199 participants

Improving HIV Prevention Among Heterosexual Men Seeking STI Services in Malawi

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-04-02
Completion:: 2025-07-28

Conditions

HIV Infection
Sexually Transmitted Infections
Pre-exposure Prophylaxis
Systems Navigation

Interventions

OTHER
DIAGNOSTIC_TEST
BEHAVIORAL

No Results Yet

NCT06179329 | RECRUITING | NA

150 participants

One-year Patency Comparison Between Radial Artery and No-touch Saphenous Vein Grafts in Women Undergoing Isolated CABG

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-01-01
Completion:: 2025-01-01

Conditions

Cardiac Disease
Surgery-Complications
Graft Failure

Interventions

PROCEDURE

No Results Yet

NCT06179199 | NOT_YET_RECRUITING | NA

40 participants

Evaluation of the Analgesic Effect of Transcranial Direct Current Stimulation (tDCS) for Sedated Patients in Intensive Care Unit.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2026-01-31
Completion:: 2026-09-30

Conditions

Transcranial Direct Current Stimulation (tDCS)

Interventions

DEVICE

No Results Yet

NCT06150716 | RECRUITING | PHASE1

24 participants

Orbit Study: A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Intrathecally Administered ION356 in Participants With Pelizaeus Merzbacher Disease (PMD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-04-10
Completion:: 2028-06-30

Conditions

Pelizaeus-Merzbacher Disease

Interventions

DRUG

No Results Yet

NCT06145477 | RECRUITING

160 participants

Parenting for Tomorrow: A New Model for Supporting Preschool Children's Mental Health in Head Start

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-11-15
Completion:: 2028-11-30

Conditions

Parenting
Parenting Intervention

Interventions

BEHAVIORAL

No Results Yet

NCT06143865 | COMPLETED | NA

67 participants

Closed Aspiration on Hemodynamic Changes and Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-07-10
Completion:: 2022-11-10

Conditions

Aspiration

Interventions

PROCEDURE

No Results Yet

NCT06140368 | COMPLETED | NA

84 participants

Virtual Realityon Pain, Anxiety and Comfort During Trigger Point Injection

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-05-10
Completion:: 2023-08-10

Conditions

Virtual Reality

Interventions

BEHAVIORAL

No Results Yet

NCT06107413 | ACTIVE_NOT_RECRUITING | PHASE2

280 participants

Study to Assess Adverse Events and Change in Disease Activity in Previously Treated Adult Participants Receiving Intravenous (IV) ABBV-400 With Unresectable Metastatic Colorectal Cancer in Combination With IV Fluorouracil, Folinic Acid, and Bevacizumab

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-11-12
Completion:: 2026-12-31

Conditions

Unresectable Metastatic Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT06102096 | COMPLETED | NA

125 participants

Culturally Adapted iCBT for Arabic-speaking Refugee and Migrant Youth With Common Mental Health Problems

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-11-27
Completion:: 2025-08-31

Conditions

Depressive Symptoms
Anxiety
Insomnia
Grief
Psychological Trauma
Resilience
Stress
Marital Relationship
Psychological Well-Being

Interventions

BEHAVIORAL

No Results Yet

NCT06102044 | RECRUITING | PHASE3

3250 participants

Zinc Supplementation for Young Infants With Clinical Severe Infection in Tanzania

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-12-27
Completion:: 2027-10-30

Conditions

Neonatal Infection

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06079775 | COMPLETED | PHASE1

53 participants

P1, DDI & MAD PK and Safety Study of Xeruborbactam Oral Prodrug in Combo With Ceftibuten in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-01-30
Completion:: 2025-01-05

Conditions

Bacterial Infections

Interventions

DRUG

No Results Yet

NCT06079697 | COMPLETED | NA

52 participants

An Exercise Prehabilitation Intervention for Improving Mobility and Recovery Outcomes in Patients Undergoing Head and Neck Cancer Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-02-01
Completion:: 2025-07-15

Conditions

Head and Neck Carcinoma

Interventions

OTHER

No Results Yet

NCT06065384 | RECRUITING | NA

44 participants

Neural Plasticity and Motor Recovery After Upper Extremity Motor Training in People With c-SCI

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-10-09
Completion:: 2027-03-28

Conditions

Spinal Cord Injuries

Interventions

OTHER

No Results Yet

NCT06062901 | COMPLETED | NA

28 participants

An Educational Intervention on Provider Knowledge for the Support of Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2021-09-17
Completion:: 2023-09-19

Conditions

Hematopoietic and Lymphoid Cell Neoplasm
Malignant Solid Neoplasm

Interventions

OTHER

No Results Yet