Clinical Trials Updated in 2025

NCT06148506 | ACTIVE_NOT_RECRUITING

376 participants

A Prospective NIS to Evaluate the Clinical Outcomes of Risarg® (Ribociclib) Combined With Endocrine Therapy or Chemotherapy in Patients With HR+HER2 - aBC in Routine Clinical Practice in the Russia

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-12-28
Completion:: 2027-06-30

Conditions

HR+HER2- Advanced Breast Cancer

Interventions

OTHER

No Results Yet

NCT06125145 | COMPLETED | NA

30 participants

Geriatric Assessment and Promotores (GAP) Pilot Feasibility Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2024-04-19
Completion:: 2025-05-10

Conditions

Breast Cancer
Colorectal Cancer
Prostate Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06105164 | RECRUITING | NA

150 participants

Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2024-12-05
Completion:: 2029-08-31

Conditions

Appetitive Behavior
Obesity

Interventions

DEVICE

No Results Yet

NCT06093269 | ACTIVE_NOT_RECRUITING | PHASE4

32 participants

Pharmacokinetics Study of Cefazolin in Hemodialysis (CEFAZODIAL)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-11-20
Completion:: 2025-12-31

Conditions

Hemodialysis Catheter Infection
Infection, Bacterial

Interventions

BIOLOGICAL

No Results Yet

NCT06032104 | RECRUITING | NA

25 participants

Feasibility and Colorectal Benefits of Pulses Supplementation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-10-27
Completion:: 2026-09-30

Conditions

Colorectal Polyp
Obesity

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06023810 | COMPLETED | NA

73 participants

The Effect of Motivational Interviewing on Treatment Adherence, Self-Efficacy, and Satisfaction in Individuals With Diabetic Foot Ulcers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-03-01
Completion:: 2023-11-01

Conditions

Foot Ulcer, Diabetic

Interventions

BEHAVIORAL

No Results Yet

NCT06023446 | ENROLLING_BY_INVITATION

100 participants

Can (Optical Coherence Tomography) Pictures of the Retina Detect Alzheimer's Disease at Its Earliest Stages?

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-09-29
Completion:: 2028-02-28

Conditions

Alzheimer Disease
Mild Cognitive Impairment

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06018064 | RECRUITING | NA

30 participants

Investigating Fit and Satisfaction of the Prone Positioner

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-09-21
Completion:: 2027-09-30

Conditions

Infant Development

Interventions

DEVICE

No Results Yet

NCT06017050 | COMPLETED | NA

138 participants

BullyDown, a Text Messaging-based Bullying Prevention Program for Middle School-aged Youth

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-08-15
Completion:: 2024-06-03

Conditions

Bullying

Interventions

BEHAVIORAL

Results Available

NCT06005285 | RECRUITING | NA

600 participants

Examining the Effectiveness of the Early Start Denver Model in Community Programs Serving Young Autism

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2024-03-01
Completion:: 2028-01-01

Conditions

Autism

Interventions

BEHAVIORAL

No Results Yet

NCT06004453 | COMPLETED

899 participants

Characterizing Guideline Adoption and Treatment Quality in Clinical Routine of German HFrEF Care

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-04-03
Completion:: 2025-01-17

Conditions

Heart Failure

Interventions

OTHER

No Results Yet

NCT05991973 | COMPLETED | PHASE2

44 participants

Low-dose Chidamide Maintenance Therapy After Allo-HSCT for T-cell Acute Lymphoblastic Leukemia or T-cell Lymphomas

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-07-15
Completion:: 2025-06-01

Conditions

T Lymphoblastic Leukemia/Lymphoma

Interventions

DRUG

No Results Yet

NCT05991466 | COMPLETED | PHASE4

141 participants

Effect of Dexmedetomidine on the Quality of Recovery in Parturients Undergoing Elective Caesarean Sections

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2022-01-01
Completion:: 2022-09-30

Conditions

The Quality of Recovery (ObsQOR-11)

Interventions

DRUG

No Results Yet

NCT05970640 | COMPLETED | PHASE1

64 participants

A Study to Test How Well Different Doses of BI 3006337 Are Tolerated by People With Overweight or Obesity and With Fatty Liver Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-08-14
Completion:: 2024-10-31

Conditions

Non-alcoholic Fatty Liver Disease
Obesity

Interventions

DRUG

Results Available

NCT05967741 | RECRUITING | NA

24 participants

The Effects of Dietary Erythritol on Platelet Reactivity and Vascular Inflammation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-07-20
Completion:: 2026-05-31

Conditions

Platelet Aggregation, Spontaneous
Vascular Thrombosis

Interventions

OTHER

No Results Yet

NCT05964231 | COMPLETED | NA

71 participants

The Intervention of Psychobiotics in Patients With Anxiety Disorders

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-08-01
Completion:: 2025-07-31

Conditions

Anxiety Disorders

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05938543 | RECRUITING | NA

20 participants

Cerebellar TMS and Satiety in Prader-Willi Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-09-01
Completion:: 2026-09-30

Conditions

Prader-Willi Syndrome

Interventions

DEVICE

No Results Yet

NCT05923112 | COMPLETED

421 participants

BESPONSA Injection 1 mg Special Investigation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-05
Start Date:: 2018-07-02
Completion:: 2024-09-06

Conditions

Acute Lymphocytic Leukemia

Results Available

NCT05917327 | TERMINATED | NA

1 participants

Performance and Safety of MEX-CD1 Low-volume Continuous Veno-venous Haemodialysis Medical Device for Copper-extraction in Patients With Wilson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2024-01-24
Completion:: 2025-09-15

Conditions

Hepatolenticular Degeneration; Wilson

Interventions

DEVICE

No Results Yet

NCT05903183 | COMPLETED | PHASE2

264 participants

A Study to Evaluate the Safety and Immunogenicity of IVX-A12 in Participants of 60 to 85 Years of Age

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-05-15
Completion:: 2023-06-05

Conditions

Healthy

Interventions

BIOLOGICAL

Results Available

NCT05880303 | COMPLETED | NA

20 participants

Effect of Nonsurgical Periodontal Therapy (NSPT) on Rheumatoid Arthritis Subjects With Periodontitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-06-01
Completion:: 2025-05-31

Conditions

Periodontitis
Rheumatoid Arthritis

Interventions

PROCEDURE

No Results Yet

NCT05841797 | COMPLETED | NA

120 participants

Evaluation of Problem Management Plus in Pregnant Women With HIV in Kenya

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-06-05
Completion:: 2025-08-12

Conditions

Human Immunodeficiency Virus

Interventions

BEHAVIORAL

No Results Yet

NCT05829421 | COMPLETED | NA

8 participants

Addressing Problems in Managing Daily Tasks Due to Poststroke Cognitive Impairments

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-05-25
Completion:: 2024-03-29

Conditions

Cognitive Impairment
Stroke

Interventions

OTHER

No Results Yet

NCT05822089 | RECRUITING | NA

461 participants

Intraindividual Comparison of EMO IOLs

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2021-12-13
Completion:: 2026-12-31

Conditions

Age Related Cataracts

Interventions

PROCEDURE

No Results Yet

NCT05781750 | TERMINATED | PHASE2

84 participants

A Study of Zetomipzomib (KZR-616) in Patients With Active Lupus Nephritis (PALIZADE)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-11-03
Completion:: 2024-11-08

Conditions

Lupus Nephritis

Interventions

DRUG

Results Available

NCT05780320 | COMPLETED

242 participants

A Pharmaco-surgical Approach to Reduce Postoperative Atrial Fibrillation After Cardiac Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-05
Start Date:: 2022-09-19
Completion:: 2024-11-15

Conditions

Atrial Fibrillation New Onset

Interventions

OTHER

No Results Yet

NCT05739994 | COMPLETED | NA

118 participants

Frontal and Parietal Contributions to Proprioception and Motor Skill Learning

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-06-09
Completion:: 2024-12-19

Conditions

Basic Science

Interventions

OTHER

Results Available

NCT05718024 | COMPLETED | PHASE4

174 participants

Night-time Dexmedetomidine-esketamine Infusion and Sleep Quality in ICU Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-11-01
Completion:: 2025-04-22

Conditions

Esketamine
Intensive Care Unit
Mechanical Ventilation
Dexmedetomidine
Sleep Quality

Interventions

DRUG

No Results Yet

NCT05714683 | NOT_YET_RECRUITING

600 participants

Regulatory Post Marketing Surveillance (rPMS) Study of Rybelsus (Oral Semaglutide) to Evaluate Safety and Effectiveness in Patients With Type 2 Diabetes Mellitus in Routine Clinical Practice in Korea

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-05
Start Date:: 2025-12-31
Completion:: 2026-10-30

Conditions

Diabetes Mellitus, Type 2

Interventions

DRUG

No Results Yet

NCT05694455 | COMPLETED | NA

68 participants

Micro and Macro Circulation in Sepsis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2022-07-01
Completion:: 2025-05-31

Conditions

Sepsis
Septic Shock

Interventions

DIAGNOSTIC_TEST
OTHER

No Results Yet

NCT05682053 | COMPLETED | NA

33 participants

Multiparametric Magnetic Resonance Imaging (MRI) in Medullary Sponge Kidney

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-03-27
Completion:: 2024-01-08

Conditions

Medullary Sponge Kidney

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05673486 | COMPLETED | NA

36 participants

Regional Anesthesia by PENG-Block in Emergency Department

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-03-31
Completion:: 2023-12-25

Conditions

Hip Fractures

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05643469 | RECRUITING | NA

1448 participants

Self-determination Plus Instant Messaging for Smokers With Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-07-03
Completion:: 2026-05-31

Conditions

Smoking
Cancer

Interventions

OTHER

No Results Yet

NCT05621252 | COMPLETED | PHASE2

10 participants

Imaging Evaluation of PLN-74809 in Participants With IPF (PLN-74809)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2022-07-13
Completion:: 2023-12-27

Conditions

Idiopathic Pulmonary Fibrosis

Interventions

DRUG

Results Available

NCT05594576 | COMPLETED | NA

481 participants

Comparison of the ENDOCUFF VISION® Endoscopy Cap Coupled With GI GENIUS™ Artificial Intelligence Compared to Each Device Alone in Improving Colonic Adenoma Detection Rate During Colonoscopy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2022-10-18
Completion:: 2024-10-11

Conditions

Colorectal Cancer
Adenoma
Intestinal Polyps

Interventions

PROCEDURE

No Results Yet

NCT05572047 | ACTIVE_NOT_RECRUITING | NA

25 participants

Coherent Sine Burst (CSE) Electroporation System Pilot Study in Patients With Atrial Fibrillation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2022-10-11
Completion:: 2026-04-30

Conditions

Atrial Fibrillation

Interventions

DEVICE

No Results Yet

NCT05571384 | COMPLETED | NA

22 participants

High Intensity Body-weight Circuit Training Feasibility and Efficacy for in Middle Aged Persons With Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2022-07-26
Completion:: 2025-07-31

Conditions

Type2diabetes

Interventions

BEHAVIORAL

No Results Yet

NCT05549258 | RECRUITING | PHASE2

15 participants

Study of Inebilizumab in Pediatric Subjects With Neuromyelitis Optica Spectrum Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2023-07-03
Completion:: 2027-04-13

Conditions

Neuromyelitis Optica Spectrum Disorder

Interventions

DRUG

No Results Yet

NCT05538351 | ACTIVE_NOT_RECRUITING

120 participants

A Study to Support the Development of the Enhanced Fluid Assessment Tool for Patients With Acute Kidney Injury

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-05
Start Date:: 2022-09-09
Completion:: 2026-08-01

Conditions

Acute Kidney Injury

Interventions

DEVICE

No Results Yet

NCT05529641 | COMPLETED | NA

71 participants

Effects of Diaphragmatic Resistance Training in People With Chronic Neck Pain.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2022-12-09
Completion:: 2025-05-31

Conditions

Neck Pain
Diaphragm
Exercise Training
Inhalation

Interventions

OTHER

No Results Yet