Clinical Trials Updated in 2025

NCT07214558 | COMPLETED

84 participants

Spinal Versus General Anesthesia and Inflammatory Response Measured by Delta Neutrophil Index in Total Knee Arthroplasty: An Observational Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-09-22
Completion:: 2025-10-22

Conditions

Inflammatory Response in Total Knee Arthroplasty

Interventions

OTHER

No Results Yet

NCT07212803 | RECRUITING | PHASE4

3 participants

Effects of Energy Drinks on Cardiovascular Endpoints

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-11-01
Completion:: 2026-03-31

Conditions

Healthy Volunteers
Safety After Oral Intake

Interventions

DIETARY_SUPPLEMENT
DRUG
OTHER

No Results Yet

NCT07211945 | NOT_YET_RECRUITING

300 participants

Loneliness as Risk Factor for Dementia

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-26
Start Date:: 2026-03-31
Completion:: 2028-09-30

Conditions

Mild Cognitive Impairment (MCI)
Dementia (Diagnosis)
Loneliness

No Results Yet

NCT07211932 | NOT_YET_RECRUITING

58 participants

Tofacitinib in Juvenile Idiopathic Arthritis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-12-31
Completion:: 2026-12-31

Conditions

Juvenile Idiopathic Arthritis (JIA)

Interventions

DRUG

No Results Yet

NCT07211867 | RECRUITING | NA

152 participants

A Digital Intervention to Decrease Self-Stigma Among Pregnant and Postpartum Women With Substance Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-11-24
Completion:: 2027-03-31

Conditions

Substance Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT07210996 | COMPLETED | PHASE1

20 participants

A Study to Evaluate the Relative Bioavailability of Pimicotinib Capsules Containing Free Base in Different Proportions in Healthy Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-09-12
Completion:: 2025-10-06

Conditions

Pharmacokinetics in Healthy Volunteers

Interventions

DRUG

No Results Yet

NCT07209839 | COMPLETED

127 participants

Pelvic Floor Knowledge and Dysfunction in Female Athletes

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-10-03
Completion:: 2025-10-27

Conditions

Pelvic Floor
Female Athletes
Physical Activity
Demographic Data

No Results Yet

NCT07205224 | COMPLETED

90 participants

Inflammatory Response Under Spinal vs General Anesthesia in PCNL: NLR, RDW, LAR.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-09-22
Completion:: 2025-10-22

Conditions

Nephrolithiasis
Postoperative Inflammation

Interventions

OTHER

No Results Yet

NCT07203326 | ACTIVE_NOT_RECRUITING | PHASE4

20 participants

Microderm for Root Coverage Procedures

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-02-13
Completion:: 2026-08-31

Conditions

Connective Tissue Graft
Gum Recession

Interventions

BIOLOGICAL

No Results Yet

NCT07187427 | NOT_YET_RECRUITING | NA

80 participants

Incidence of Pruritus Using Intrathecal Fentanyl Versus Epidural Fentanyl to Initiate Labour Analgesia.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2026-01-31
Completion:: 2026-12-31

Conditions

Pruritis
Hypotension Drug-Induced
Urinary Retention
Fetal Bradycardia During Labor
Nausea and Vomitting
Satisfaction, Patient
Labor Analgesia
Neuraxial Opioid
Opioid Analgesic Adverse Reaction
Term Labour
Fentanyl Analgesia
Fentanyl Adverse Reaction

Interventions

PROCEDURE

No Results Yet

NCT07185269 | RECRUITING | PHASE1/PHASE2

198 participants

The Purpose of This Study is to Evaluate the Efficacy and Safety of 626 in the Treatment of SLE

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-09-24
Completion:: 2028-08-12

Conditions

Systemic Lupus Erythematosus (SLE)

Interventions

DRUG

No Results Yet

NCT07184190 | COMPLETED | NA

12 participants

Effects of Trancutaneous Auriculotemporal Nerve Stimulation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-09-26
Completion:: 2025-11-14

Conditions

Healthy

Interventions

OTHER

No Results Yet

NCT07183774 | RECRUITING

104 participants

Does Sarcopenia Influence Rotator Cuff Tear Patterns? Radiological Insights From Patients With Rotator Cuff Syndrome

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-01-01
Completion:: 2025-12-01

Conditions

Rotator Cuff Tears
Sarcopenia
Shoulder Pain
Rotator Cuff Syndrome

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07170007 | RECRUITING | NA

82 participants

Physiotherapeutic Protocol Compared to Usual Care in the Treatment of Primiparas After Perineal Trauma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-11-11
Completion:: 2027-08-31

Conditions

Episiotomy
Lacerations Perineal
Obstetric Anal Sphincter Injury
Perineal Injury
Perineal Laceration, Tear, or Rupture During Delivery
Perineal Pain
Perineal Tear Resulting From Childbirth
Perineal Tear and Episiotomy

Interventions

OTHER

No Results Yet

NCT07151599 | RECRUITING | NA

84 participants

Efficacy of Combined Fractional Er:Glass and Thulium Lasers Versus Microneedling for Atrophic Acne Scars

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-10-16
Completion:: 2026-05-31

Conditions

Acne Scars

Interventions

DEVICE

No Results Yet

NCT07123480 | ACTIVE_NOT_RECRUITING | NA

160 participants

The Role of 4 Different Consent Approaches on a Pilot Study to Increase Cardiac Rehabilitation Attendance

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-07-16
Completion:: 2026-01-31

Conditions

Ethics
Cardiac Rehabilitation
Coronary Heart Disease (CHD)
Heart Failure
Percutaneous Coronary Intervention (PCI)
Aortic Valve Replacement
Myocardial Infarction (MI)

Interventions

BEHAVIORAL

No Results Yet

NCT07122843 | RECRUITING | NA

38 participants

VR AI Meditation for Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-11-06
Completion:: 2026-10-20

Conditions

Pain and Anxiety

Interventions

DEVICE

No Results Yet

NCT07122544 | RECRUITING | NA

80 participants

Pulmonary Rehabilitation in Salt Chambers for Patients With COPD

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-09-01
Completion:: 2027-01-01

Conditions

COPD (Chronic Obstructive Pulmonary Disease)

Interventions

BEHAVIORAL

No Results Yet

NCT07109570 | RECRUITING

60 participants

Surface Electrical Myography, Oxygen Consumption, Effort, and Weaning in the Mechanically Ventilated Patient in the Intensive Care Unit

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-07-08
Completion:: 2028-12-31

Conditions

Critical Illness
Intensive Care Units (ICUs)
Weaning Failure
Mechanical Ventilation
Spontaneous Breathing Trial
Diaphragm Electrical Activity
Oxygen Consumption

No Results Yet

NCT07105215 | RECRUITING | PHASE1/PHASE2

312 participants

A I/II Phase Clinical Study to Evaluate the Safety and Efficacy of RC278 in the Treatment of Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-08-11
Completion:: 2027-12-31

Conditions

Solid Tumors

Interventions

DRUG

No Results Yet

NCT07095140 | RECRUITING | NA

20 participants

Studying the Effects of Nicotine Concentration and Flavor on Alcohol Use in Young Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-09-03
Completion:: 2027-12-31

Conditions

Alcohol-Related Carcinoma

Interventions

OTHER
DRUG

No Results Yet

NCT07092475 | WITHDRAWN | PHASE3

0 participants

The Impact of Intraoperative Methadone on Postoperative Opioid Use

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-11-30
Completion:: 2025-11-30

Conditions

Breast Cancer
Opioid Use

Interventions

DRUG

No Results Yet

NCT07086235 | COMPLETED | NA

44 participants

Remineralization Capacity and Patient Satisfaction of Self-Assembling Peptide With Fluoride Versus Tooth Protective Coating With Surface Pre-Reacted Glass on White Spot Lesions

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-02-16
Completion:: 2025-08-16

Conditions

White Spot Lesions

Interventions

DRUG

No Results Yet

NCT07084662 | RECRUITING | PHASE2/PHASE3

80 participants

Xinlikang Capsule for Chemotherapy-induced Fatigue and Immune Disorders in Diffuse Large B Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-09-11
Completion:: 2028-08-01

Conditions

Diffuse Large B-Cell Lymphoma (DLBCL)

Interventions

DRUG

No Results Yet

NCT07078461 | RECRUITING | NA

25 participants

Investigating the Safety and Efficacy of the 1927-nm Thulium Laser in Keratosis Pilaris

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-10-23
Completion:: 2026-12-31

Conditions

Keratosis Pilaris (KP)

Interventions

DEVICE

No Results Yet

NCT07076433 | COMPLETED | NA

30 participants

Comparing the Efficacy of Core Stability Exercises and Pilates in Fibromyalgia Management: A Randomized Controlled Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-09-15
Completion:: 2025-10-15

Conditions

Fibromyositis-Fibromyalgia Syndrome

Interventions

OTHER

No Results Yet

NCT07072039 | RECRUITING | NA

50 participants

Evaluation of the Paramedic Evaluation for Acute COPD Exacerbation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-10-01
Completion:: 2029-07-01

Conditions

COPD (Chronic Obstructive Pulmonary Disease)

Interventions

PROCEDURE

No Results Yet

NCT07070323 | RECRUITING | PHASE1/PHASE2

54 participants

A Multicenter, Open-Label, Non-Randomized, Single-Arm Clinical Study of Nanobody CD5-CAR T Cell Therapy for Refractory/Relapsed T Lymphocyte Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-07-09
Completion:: 2026-12-31

Conditions

T-Cell Acute Lymphocytic Leukemia
Acute Lymphoblastic Leukemia, in Relapse
Refractory Acute Lymphoblastic Leukemia
T-cell Malignancies

Interventions

DRUG

No Results Yet

NCT07063446 | RECRUITING | NA

10 participants

sTMS Combined With CIMT and taVNS In Infants With Hemiplegia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-11-07
Completion:: 2026-10-31

Conditions

Hemiplegia
Perinatal Brain Injury

Interventions

DEVICE

No Results Yet

NCT07058519 | RECRUITING | PHASE2

250 participants

A Study of Osimertinib-based Adaptive Treatment Guided by ctDNA EGFRm+ Monitoring in NSCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-09-23
Completion:: 2029-01-24

Conditions

Locally Advanced or Metastatic EGFRm Non-small Cell Lung Cancer (NSCLC)

Interventions

DRUG

No Results Yet

NCT07057063 | RECRUITING | NA

80 participants

Light Therapy on Pain and Synovitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-07-13
Completion:: 2026-05-28

Conditions

Knee Pain Chronic
Synovitis of Knee
Light Therapy

Interventions

DEVICE

No Results Yet

NCT07044583 | RECRUITING | NA

68 participants

SAVE Trial: SAfe Opioid Use Video Education

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-10-27
Completion:: 2027-08-31

Conditions

Breast Reconstruction
Breast Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT07039578 | RECRUITING | PHASE2

90 participants

Study Evaluating the Efficacy and Safety of CM336 Injection in the Treatment of Light-Chain Amyloidosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-07-25
Completion:: 2026-06-30

Conditions

Primary Light-Chain Amyloidosis

Interventions

BIOLOGICAL

No Results Yet

NCT07028164 | COMPLETED

1008 participants

Clinical Features and Prognosis of Asymptomatic Biliary Dilatation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-26
Start Date:: 2024-01-01
Completion:: 2025-07-30

Conditions

Choledochal Cyst

No Results Yet

NCT07018635 | COMPLETED | PHASE1

63 participants

A Study to Assess the Effect of Itraconazole, Rifampin, and Acid-Reducing Agents on INCB161734 Pharmacokinetics When Administered Orally in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-07-16
Completion:: 2025-09-29

Conditions

Healthy Participants

Interventions

DRUG

No Results Yet

NCT07008352 | COMPLETED

100 participants

Amino Acid Metabolism Before and After Bariatric Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-06-11
Completion:: 2025-10-02

Conditions

Obesity, Morbid

Interventions

PROCEDURE

No Results Yet

NCT07003568 | RECRUITING | PHASE1

18 participants

Dual-target BCMA-GPRC5D CAR-T Cell Therapy for RR/MM With Extramedullary Infiltration

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-05-25
Completion:: 2027-05-25

Conditions

Relapsed or Refractory Multiple Myeloma (RRMM)

Interventions

DRUG

No Results Yet

NCT07003555 | RECRUITING | PHASE1

18 participants

Dual-target BCMA-CD19 CAR-T Cell Therapy for RR/MM With Extramedullary Infiltration

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-05-25
Completion:: 2027-05-25

Conditions

Relapsed or Refractory Multiple Myeloma (RRMM)

Interventions

DRUG

No Results Yet

NCT06987435 | COMPLETED

75 participants

Elasticity of Structures Around the Ankle in Chronic Ankle Instability

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-06-01
Completion:: 2025-08-15

Conditions

Chronic Ankle Instability

No Results Yet

NCT06984146 | RECRUITING | PHASE2

54 participants

Nivo40-AVD for Advanced Classic Hodgkin Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-04-15
Completion:: 2028-01-31

Conditions

Hodgkin Lymphoma, Adult

Interventions

DRUG

No Results Yet