Clinical Trials Updated in 2025

NCT03584516 | TERMINATED | PHASE2/PHASE3

155 participants

GRAVITAS-309: Itacitinib and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-20
Start Date:: 2019-01-17
Completion:: 2023-11-03

Conditions

Chronic Graft-versus-host Disease

Interventions

DRUG

Results Available

NCT03484364 | COMPLETED | NA

182 participants

Engaging Native Hawaiian/Pacific Islanders and Activating Communities to Take Steps (ENACTS)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-20
Start Date:: 2018-06-15
Completion:: 2025-01-24

Conditions

Hypertension

Interventions

BEHAVIORAL

No Results Yet

NCT03467243 | COMPLETED | NA

191 participants

Evaluating the Use of Peer Specialists to Deliver Cognitive Behavioral Social Skills Training

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-20
Start Date:: 2018-08-15
Completion:: 2025-08-29

Conditions

Serious Mental Illness

Interventions

BEHAVIORAL

No Results Yet

NCT03461120 | ACTIVE_NOT_RECRUITING | PHASE4

203 participants

Improving Postamputation Functioning by Decreasing Phantom Pain With Perioperative Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-20
Start Date:: 2018-03-23
Completion:: 2026-08-18

Conditions

Lower Extremity Surgical Amputation
Post-amputation Phantom Limb Pain

Interventions

DRUG

No Results Yet

NCT03101813 | RECRUITING

1500 participants

International Diffuse Intrinsic Pontine Glioma (DIPG)/Diffuse Midline Glioma (DMG) Registry and Repository

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-20
Start Date:: 2012-06-30
Completion:: 2037-06-30

Conditions

Diffuse Intrinsic Pontine Glioma
Diffuse Midline Glioma, H3 K27M-Mutant
Diffuse Midline Glioma

No Results Yet

NCT02386553 | COMPLETED | PHASE2

25 participants

A Study of Multiple Doses of Nusinersen (ISIS 396443) Delivered to Infants With Genetically Diagnosed and Presymptomatic Spinal Muscular Atrophy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-20
Start Date:: 2015-05-18
Completion:: 2024-12-17

Conditions

Spinal Muscular Atrophy

Interventions

DRUG

Results Available

NCT02305537 | COMPLETED | NA

559 participants

Building an Outcomes Assessment Infrastructure to Assess Anxiety Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-20
Start Date:: 2014-10-31
Completion:: 2024-11-30

Conditions

Social Anxiety Disorder
Specific Phobia
Separation Anxiety Disorder
Panic Disorder
Agoraphobia
Obsessive-Compulsive Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT02252172 | COMPLETED | PHASE3

737 participants

Study Comparing Daratumumab, Lenalidomide, and Dexamethasone With Lenalidomide and Dexamethasone in Participants With Previously Untreated Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-20
Start Date:: 2015-02-16
Completion:: 2018-09-24

Conditions

Multiple Myeloma

Interventions

DRUG

Results Available

NCT01991977 | COMPLETED | PHASE2

91 participants

18F-DOPA-PET in Finding Tumors in Patients With Newly Diagnosed Gliomas Undergoing Radiation Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-20
Start Date:: 2013-12-31
Completion:: 2019-07-01

Conditions

Malignant Glioma

Interventions

PROCEDURE
DRUG
RADIATION
OTHER

Results Available

NCT01748916 | COMPLETED | NA

16 participants

Comparison of Carotenoid Bioavailability From Fresh Papaya, Tomato and Carrot

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-20
Start Date:: 2011-06-30
Completion:: 2011-11-30

Conditions

Focus of Study: Carotenoid Absorption

Interventions

OTHER

Results Available

NCT01711632 | COMPLETED | PHASE2

36 participants

BRAF Inhibitor, Vemurafenib, in Patients With Relapsed or Refractory Hairy Cell Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-20
Start Date:: 2012-10-31
Completion:: 2024-08-16

Conditions

Hairy Cell Leukemia

Interventions

DRUG

Results Available

NCT01696773 | ACTIVE_NOT_RECRUITING | NA

12 participants

Carotenoid and Flavonoid Absorption From Red and Tangerine-Type Tomatoes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-20
Start Date:: 2012-10-31
Completion:: 2013-09-30

Conditions

Carotenoid and Flavonoid Absorption

Interventions

OTHER

Results Available

NCT01136122 | WITHDRAWN | NA

0 participants

Effects of PAP Treatment of OSA in Patients With Heart Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-20
Start Date:: 2010-04-30
Completion:: 2013-10-31

Conditions

Obstructive Sleep Apnea

Interventions

DEVICE

No Results Yet

NCT00136435 | COMPLETED | PHASE2

100 participants

A Study in Adults With Untreated Acute Lymphoblastic Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-20
Start Date:: 2002-06-30
Completion:: 2008-11-30

Conditions

Acute Lymphoblastic Leukemia

Interventions

DRUG
RADIATION

Results Available

NCT07218224 | AVAILABLE

Expanded Access:18F-Fluorocholine for the Detection of Parathyroid Adenomas

Study Type:: EXPANDED_ACCESS
Last Updated:: 2025-10-17

Conditions

Parathyroid Adenomas

Interventions

DRUG
PROCEDURE

No Results Yet

NCT07218107 | COMPLETED | NA

4 participants

Neurostimulation Exosuit Augmented Training (NEAT) in the Clinic

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-17
Start Date:: 2024-06-04
Completion:: 2024-10-23

Conditions

Stroke

Interventions

DEVICE

No Results Yet

NCT07218042 | ACTIVE_NOT_RECRUITING | NA

126 participants

Study of Procedural Efficiency in EBUS With Dual Versus Single NEEDLEs: Evaluating the Value of a Second Needle in EBUS as it Pertains to Economic and Environmental Impact

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-17
Start Date:: 2024-02-02
Completion:: 2025-08-01

Conditions

Mediastinal and Hilar Lymphadenopathy

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07217847 | NOT_YET_RECRUITING | NA

56 participants

Testing SHAPE: A Single-Session Intervention Targeting Binge Eating in Women Through Assessment and Values-Based Strategies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-17
Start Date:: 2025-10-31
Completion:: 2026-10-31

Conditions

Binge Eating
Binge Eating Behaviour
Binge Eating/Loss of Control Eating
Body Image
Body Image Disturbance

Interventions

BEHAVIORAL

No Results Yet

NCT07217730 | ENROLLING_BY_INVITATION

100 participants

Healthcare Integrity & Anti-Fraud Enforcement

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-17
Start Date:: 2025-10-13
Completion:: 2034-10-13

Conditions

Healthcare Fraud Schemes
Kickback Networks
Supply Chain Vulnerabilities
Governance Failures
Whistleblower Activation
Regulatory Escalation Pathways
Validator Oversight & DAO Governance
Public Transparency & Auditability

Interventions

OTHER
DEVICE
DRUG

No Results Yet

NCT07211373 | ENROLLING_BY_INVITATION | NA

50 participants

Advancing Student Suicide Interventions With Scalable Technologies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-17
Start Date:: 2025-10-08
Completion:: 2027-06-30

Conditions

Suicidal Ideation
Suicide Attempt
Self-Harm

Interventions

DEVICE
BEHAVIORAL

No Results Yet

NCT07176988 | RECRUITING | NA

120 participants

Deconstructing Voice Therapy: Towards Enhanced Communication Outcomes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-17
Start Date:: 2025-09-03
Completion:: 2029-04-30

Conditions

Dysphonia
Primary Muscle Tension Dysphonia (MTD)

Interventions

OTHER

No Results Yet

NCT07096271 | RECRUITING | NA

1000 participants

Get Better Together: Relationship Education For Military Couples

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-17
Start Date:: 2025-09-22
Completion:: 2027-05-31

Conditions

Emotion Regulation
Relationship Conflict
Suicide Risk
Alcohol Use
Intimate Partner Violence (IPV)
Relationship Distress
Interpersonal Emotion Regulation

Interventions

BEHAVIORAL

No Results Yet

NCT07089745 | RECRUITING | NA

30 participants

Comparative Efficacy of Organizational Skills Training (OST) and Mindfulness-Based Intervention (MBI)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-17
Start Date:: 2025-09-18
Completion:: 2026-09-30

Conditions

ADHD
ADHD - Attention Deficit Disorder With Hyperactivity

Interventions

BEHAVIORAL

No Results Yet

NCT07060664 | NOT_YET_RECRUITING | NA

100 participants

Study on Outcomes of Proximal Humerus Fractures

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-17
Start Date:: 2026-09-01
Completion:: 2028-05-01

Conditions

Proximal Humerus Fracture

Interventions

PROCEDURE

No Results Yet

NCT07016568 | COMPLETED | NA

4 participants

Temporary Aortic Occlusion With the Abdominal Tourniquet for Refractory Postpartum Haemorrhage: A Proof-of-Concept Study in a War-Affected Region

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-17
Start Date:: 2024-12-01
Completion:: 2025-04-15

Conditions

Postpartum Haemorrhage (PPH)

Interventions

DEVICE

Results Available

NCT06982508 | RECRUITING | PHASE2

100 participants

Evaluation of Obicetrapib on Antioxidant Levels in Plasma and HDL Particles of Healthy Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-17
Start Date:: 2025-09-09
Completion:: 2026-09-30

Conditions

Antioxidant Absorption

Interventions

DRUG

No Results Yet

NCT06924892 | COMPLETED | NA

84 participants

Assessment of Music Experiences in Navigating Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-17
Start Date:: 2023-04-05
Completion:: 2025-03-24

Conditions

Depression

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06858839 | ACTIVE_NOT_RECRUITING | PHASE3

3853 participants

Evaluation of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-17
Start Date:: 2025-03-12
Completion:: 2027-01-21

Conditions

Obesity

Interventions

DRUG

No Results Yet

NCT06828991 | RECRUITING | PHASE2

40 participants

A Study to Evaluate the Impact of Mosunetuzumab Consolidation for Older Patients With Diffuse Large B-cell Lymphoma (DLBCL) Who Have Detectable Amounts of ctDNA (Circulating Tumor DNA) at the End of Treatment With Pola-R-mini-CHP

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-17
Start Date:: 2025-09-04
Completion:: 2029-04-01

Conditions

Diffuse Large B-Cell Lymphoma (DLBCL)

Interventions

DRUG
DEVICE

No Results Yet

NCT06774144 | ENROLLING_BY_INVITATION | PHASE3

385 participants

Rezafungin Prophylaxis in Liver Transplant

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-17
Start Date:: 2025-10-15
Completion:: 2028-12-31

Conditions

Liver Transplant Infection
Fungal Infection

Interventions

DRUG

No Results Yet

NCT06678750 | WITHDRAWN | NA

0 participants

A Prospective Clinical Study Evaluating the Newton™ TKA Protocol

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-17
Start Date:: 2024-12-31
Completion:: 2026-06-30

Conditions

Total Knee Arthroplasty

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT06654271 | ACTIVE_NOT_RECRUITING | NA

440 participants

Robotic Versus Electromagnetic Bronchoscopy for Pulmonary LesIon AssessmeNT Using Integrated Intraprocedural Imaging

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-17
Start Date:: 2024-11-11
Completion:: 2025-10-14

Conditions

Peripheral Pulmonary Lesion
Lung Nodule, Solitary

Interventions

DEVICE

No Results Yet

NCT06632379 | RECRUITING | PHASE4

76 participants

AtorvaStatin Postpartum and Reduction of Cardiovascular risK

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-17
Start Date:: 2025-10-03
Completion:: 2026-09-15

Conditions

Hypertensive Disorders of Pregnancy
Preeclampsia
Gestational Hypertension

Interventions

DRUG

No Results Yet

NCT06631313 | COMPLETED | NA

43 participants

PureWick™ Adolescent Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-17
Start Date:: 2024-08-28
Completion:: 2024-09-10

Conditions

Healthy Volunteers, Adolescent

Interventions

DEVICE

Results Available

NCT06547008 | RECRUITING | PHASE1

57 participants

Army-SPRING Army-Suicide Prevention Research

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-17
Start Date:: 2025-03-19
Completion:: 2027-09-30

Conditions

Suicide

Interventions

BEHAVIORAL

No Results Yet

NCT06420492 | RECRUITING | PHASE2

20 participants

Study of Novel Therapeutics for Acute Remedy of Colitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-17
Start Date:: 2025-09-30
Completion:: 2026-12-01

Conditions

Ulcerative Colitis
Ulcerative Colitis Chronic Moderate
Ulcerative Colitis Chronic Severe

Interventions

DRUG

No Results Yet

NCT06412601 | ACTIVE_NOT_RECRUITING | NA

80 participants

Happy Bob App: A Preliminary Evaluation of Its Use in Youth With Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-17
Start Date:: 2024-07-30
Completion:: 2026-09-30

Conditions

Type 1 Diabetes

Interventions

BEHAVIORAL

No Results Yet

NCT06385587 | COMPLETED

33 participants

Technology-based Symptom Monitoring Intervention for Locally Advanced Head and Neck Cancer Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-17
Start Date:: 2024-06-06
Completion:: 2025-09-25

Conditions

Head and Neck Cancer

Interventions

DEVICE

No Results Yet

NCT06282042 | RECRUITING | NA

250 participants

Early Transcatheter Mitral Valve Repair After Myocardial Infarction

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-17
Start Date:: 2024-12-24
Completion:: 2027-06-16

Conditions

Acute Mitral Regurgitation

Interventions

PROCEDURE
DEVICE
OTHER

No Results Yet

NCT06265428 | ACTIVE_NOT_RECRUITING | PHASE3

228 participants

A Study to Compare DB-1303/BNT323 Versus T-DM1 in Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-17
Start Date:: 2024-01-29
Completion:: 2026-02-28

Conditions

HER2-positive Breast Cancer

Interventions

DRUG

No Results Yet