Clinical Trials

NCT06366672 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

20 participants

Evaluating the Human Immune Response to the JYNNEOS Vaccine

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2024-06-10

Completion:

2026-09-30

Conditions

• Vaccinia
• Virus Diseases

Interventions

• BIOLOGICAL
• PROCEDURE

No Results Yet

NCT06160804 | TERMINATED | NA

18 participants

Evaluating Femoral Traction

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2024-03-19

Completion:

2025-09-23

Conditions

• Femoral Shaft Fracture

Interventions

• PROCEDURE

No Results Yet

NCT06028438 | COMPLETED | PHASE2

103 participants

A Study to Evaluate the Nipocalimab and Certolizumab Combination Therapy in Participants With Active Rheumatoid Arthritis

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2023-08-15

Completion:

2024-08-29

Conditions

• Arthritis, Rheumatoid

Interventions

• DRUG

Results Available

NCT06002906 | ACTIVE_NOT_RECRUITING | PHASE4

300 participants

The Use of Indocyanine Green to Visualize Blood Flow to the Gastrojejunostomy During Bariatric Surgery.

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2023-01-25

Completion:

2027-07-03

Conditions

• Ulcer, Gastric
• Obesity, Morbid

Interventions

• DRUG
• DEVICE

No Results Yet

NCT05938452 | COMPLETED | PHASE1

40 participants

Safety and Tolerability of Glyceryl Tribenzoate (GTB) Capsules in Healthy Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2022-12-12

Completion:

2023-10-19

Conditions

• Neurological Disorder

Interventions

• DRUG

No Results Yet

NCT05860959 | COMPLETED

480 participants

SUBLOCADE Long-term Outcomes

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-16

Start Date:

2023-08-31

Completion:

2025-08-31

Conditions

• Opioid Use Disorder

No Results Yet

NCT05854303 | RECRUITING

26 participants

Effect of Opioid Cessation on Opioid-Induced Esophageal Dysfunction

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-16

Start Date:

2023-09-18

Completion:

2026-11-30

Conditions

• Opioid-Induced Esophageal Dysfunction

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT05795153 | COMPLETED | PHASE3

144 participants

A Multicenter, Open-label Phase 3 Study: Ambulatory Blood Pressure Monitoring in Adult Patients With Chronic Spontaneous Urticaria Inadequately Controlled by H1-antihistamines Treated With Remibrutinib up to 12 Weeks.

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2023-04-05

Completion:

2024-04-25

Conditions

• Chronic Spontaneous Urticaria

Interventions

• DRUG

Results Available

NCT05787483 | COMPLETED | NA

68 participants

Biopsychosocial Outcomes of Mindfulness-based Instruction

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2023-08-14

Completion:

2024-10-16

Conditions

• Specific Learning Disability
• Mental Health Issue

Interventions

• BEHAVIORAL

No Results Yet

NCT05778578 | TERMINATED | NA

194 participants

Universal Basic Income and Structural Racism in the US South

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2023-09-28

Completion:

2025-03-13

Conditions

• Health Care Utilization

Interventions

• BEHAVIORAL

No Results Yet

NCT05767736 | ACTIVE_NOT_RECRUITING

10500 participants

A Study to Evaluate Long-Term Safety of Vumerity and Tecfidera in Participants With Multiple Sclerosis (MS)

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-16

Start Date:

2024-06-08

Completion:

2032-12-01

Conditions

• Multiple Sclerosis

Interventions

• DRUG

No Results Yet

NCT05763875 | COMPLETED | PHASE3

350 participants

Efficacy and Safety of Inclisiran as Monotherapy in Patients With Primary Hypercholesterolemia Not Receiving Lipid-lowering Therapy.

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2023-03-15

Completion:

2024-06-20

Conditions

• Hypercholesterolemia

Interventions

• DRUG

Results Available

NCT05758194 | COMPLETED | NA

20 participants

Mitigating Post-Op RV Dysfunction After LVAD Implantation

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2023-03-22

Completion:

2024-12-31

Conditions

• Heart Failure
• Right Ventricular Dysfunction
• Right Ventricular Failure

Interventions

• OTHER

No Results Yet

NCT05639751 | COMPLETED | PHASE1

135 participants

PRT3789 Monotherapy and in Combo w/Docetaxel in Participants w/Advanced or Metastatic Solid Tumors w/SMARCA4 Mutation

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2023-05-02

Completion:

2025-10-01

Conditions

• Advanced Solid Tumor
• Metastatic Solid Tumor
• Non-small Cell Lung Cancers
• SMARCA4 Gene Mutation

Interventions

• DRUG

No Results Yet

NCT05620329 | RECRUITING

9999 participants

UNC Pleural Fluid Registry

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-16

Start Date:

2018-01-24

Completion:

2050-01-24

Conditions

• Lung Cancer
• Lung Infection
• Breast Cancer
• Malignant Pleural Effusion
• Empyema

No Results Yet

NCT05615688 | COMPLETED | NA

94 participants

Pain and Activity Levels After Orthodontic Separators

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2022-07-14

Completion:

2025-09-30

Conditions

• Dental Malocclusion

Interventions

• PROCEDURE

No Results Yet

NCT05605340 | ACTIVE_NOT_RECRUITING | NA

35 participants

Healthier At-home Meals for Expectant Mothers

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2023-08-09

Completion:

2025-10-14

Conditions

• Pregnancy Related
• Weight Gain, Maternal

Interventions

• BEHAVIORAL

No Results Yet

NCT05567744 | RECRUITING

2500 participants

Registry for CADASIL

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-16

Start Date:

2022-06-03

Completion:

2027-10-31

Conditions

• Cerebral Autosomal Dominant Ateriopathy With Subcortical Infarcts and Leukoencephalopathy

Interventions

• OTHER

No Results Yet

NCT05565417 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

67 participants

Study of the Monoclonal Antibody IMT-009 in Patients With Advanced Solid Tumors or Lymphomas

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2022-11-28

Completion:

2026-01-31

Conditions

• Non Small Cell Lung Cancer
• Head and Neck Squamous Cell Carcinoma
• Triple Negative Breast Cancer
• Cutaneous Squamous Cell Carcinoma
• Hormone Receptor Positive Breast Carcinoma
• Small Bowel Cancer
• Esophageal Cancer
• Colorectal Cancer
• Diffuse Large B Cell Lymphoma
• Hodgkin Lymphoma
• Burkitt Lymphoma
• Follicular Lymphoma

Interventions

• DRUG
• COMBINATION_PRODUCT

No Results Yet

NCT05539209 | COMPLETED | NA

512 participants

Testing a Novel Smartphone Application for Smoking Cessation With the Oklahoma Helpline

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2022-09-13

Completion:

2025-09-29

Conditions

• Smoking Cessation

Interventions

• BEHAVIORAL

No Results Yet

NCT05501262 | RECRUITING | NA

32 participants

Comparative Effectiveness of Cryoablation Versus Steroid and Lidocaine Alone for Treatment of Morton's Neuroma

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2022-07-25

Completion:

2026-12-30

Conditions

• Morton Neuroma

Interventions

• DEVICE
• PROCEDURE

No Results Yet

NCT05400655 | COMPLETED | PHASE2

912 participants

Anti-malaria MAb in Kenyan Children

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2022-09-14

Completion:

2024-06-02

Conditions

• Plasmodium Falciparum Infection
• Malaria

Interventions

• DRUG
• OTHER

Results Available

NCT05343000 | COMPLETED | NA

17 participants

Lifestyle Program for Obstructive Sleep Apnea With Severe Obesity

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2024-02-03

Completion:

2024-09-25

Conditions

• Obstructive Sleep Apnea
• Obesity

Interventions

• BEHAVIORAL

Results Available

NCT05321420 | ACTIVE_NOT_RECRUITING | PHASE2

240 participants

LYT-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2022-07-22

Completion:

2024-10-15

Conditions

• Idiopathic Pulmonary Fibrosis

Interventions

• DRUG

No Results Yet

NCT05247853 | COMPLETED

3127 participants

HPV Vaccine Effectiveness Study in Rwandan Women Living With HIV

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-16

Start Date:

2021-11-03

Completion:

2024-12-12

Conditions

• Cervical Cancer
• Human Papilloma Virus
• Human Immunodeficiency Virus
• HPV-Related Carcinoma

Interventions

• PROCEDURE

No Results Yet

NCT05151744 | COMPLETED | PHASE2

187 participants

A Study to Investigate Vamikibart (RO7200220) in Combination With Ranibizumab in Diabetic Macular Edema

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2021-12-17

Completion:

2024-04-17

Conditions

• Diabetic Macular Edema

Interventions

• DRUG
• OTHER

Results Available

NCT05088460 | TERMINATED | PHASE2

20 participants

A Study to Examine the Effects of the Leptin Receptor (LEPR) Agonist Antibody REGN4461 in Adult Patients With Familial Partial Lipodystrophy (FPLD)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2022-02-28

Completion:

2023-12-13

Conditions

• Familial Partial Lipodystrophy
• Metabolic Abnormalities

Interventions

• DRUG

Results Available

NCT05086744 | TERMINATED | PHASE2

19 participants

Basket Study to Assess Efficacy, Safety and PK of Iptacopan (LNP023) in Autoimmune Benign Hematological Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2021-12-21

Completion:

2023-09-20

Conditions

• Immune Thrombocytopenia (ITP)
• Cold Agglutinin Disease (CAD)

Interventions

• DRUG

Results Available

NCT05082610 | COMPLETED | PHASE1

48 participants

A Study of HMBD-002, a Monoclonal Antibody Targeting VISTA, as Monotherapy and Combined With Pembrolizumab, in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2022-02-28

Completion:

2024-11-05

Conditions

• Cancer
• Tumor, Solid
• Nonsmall Cell Lung Cancer
• Triple Negative Breast Cancer
• Malignant Neoplasm
• Metastatic Cancer
• Advanced Solid Tumor

Interventions

• DRUG

No Results Yet

NCT05061108 | ACTIVE_NOT_RECRUITING | NA

330 participants

Linkage, Empowerment, and Access to Prevent Hypertension

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2022-08-08

Completion:

2026-09-30

Conditions

• Hypertension
• Blood Pressure
• Cardiovascular Disease Other

Interventions

• BEHAVIORAL

No Results Yet

NCT04986657 | RECRUITING | NA

325 participants

Whole Genome Sequencing (ChromoSeq) as an Adjunct to Conventional Genomic Profiling in AML and MDS

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2021-09-17

Completion:

2027-12-31

Conditions

• Whole Genome Sequencing
• Acute Myeloid Leukemia
• Myelodysplastic Syndromes

Interventions

• DEVICE

No Results Yet

NCT04955691 | COMPLETED | NA

19 participants

Metabolic Changes Induced by a Very Low Carbohydrate Diet in Youth With Type 1 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2021-07-29

Completion:

2024-08-06

Conditions

• Type1diabetes, Low Carbohydrate Diet

Interventions

• OTHER

Results Available

NCT04926831 | TERMINATED | PHASE2

4 participants

Phase II of Neoadjuvant and Adjuvant Capmatinib in NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2022-08-10

Completion:

2024-03-13

Conditions

• Non-small Cell Lung Cancer

Interventions

• DRUG

Results Available

NCT04878432 | TERMINATED | PHASE2

39 participants

STIMULUS MDS-US : Sabatolimab Added to HMA in Higher Risk MDS

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2022-03-17

Completion:

2023-10-26

Conditions

• Myelodysplastic Syndrome (MDS)

Interventions

• DRUG

Results Available

NCT04873934 | COMPLETED | PHASE3

400 participants

Management of LDL-cholesterol With Inclisiran + Usual Care Compared to Usual Care Alone in Participants With a Recent Acute Coronary Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2021-06-24

Completion:

2024-08-07

Conditions

• Acute Coronary Syndrome

Interventions

• DRUG

Results Available

NCT04873869 | TERMINATED | PHASE2

8 participants

Study to Evaluate NBI-921352 as Adjunctive Therapy in Subjects With SCN8A Developmental and Epileptic Encephalopathy Syndrome (SCN8A-DEE)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2022-01-31

Completion:

2023-03-17

Conditions

• SCN8A Developmental and Epileptic Encephalopathy Syndrome

Interventions

• DRUG

Results Available

NCT04818034 | COMPLETED | PHASE2

10 participants

The Effect of Sodium-glucose Cotransporter (SGLT) 2 Inhibitors on Cystine Stone Formation: A Preliminary Study

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2021-08-30

Completion:

2021-12-13

Conditions

• Cystinuria

Interventions

• DRUG

Results Available

NCT04795466 | TERMINATED | PHASE2

34 participants

Study of the Efficacy and Safety of Various Anti-inflammatory Agents in Participants With Mild Cognitive Impairment or Mild Alzheimer's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2021-10-28

Completion:

2024-03-07

Conditions

• Mild Cognitive Impairment
• Alzheimer Disease

Interventions

• BIOLOGICAL
• OTHER

Results Available

NCT04781972 | RECRUITING | PHASE4

30 participants

Multimodal Brain Imaging of the Neural Effects of Methylphenidate in Patients With ADHD

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-16

Start Date:

2021-07-27

Completion:

2028-11-30

Conditions

• ADHD - Combined Type

Interventions

• DRUG

No Results Yet

NCT04775537 | RECRUITING

120 participants

OssiMend BA in Posterolateral Instrumented Lumbar Fusion

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-16

Start Date:

2021-01-21

Completion:

2026-12-30

Conditions

• Spinal Disease
• Degenerative Disc Disease

Interventions

• DEVICE

No Results Yet