Clinical Trials Updated in 2025

NCT06742086 | COMPLETED | PHASE1

72 participants

A Study to Evaluate the Bioavailability and Food Effects of Oral Venetoclax New Tablet Formulation 2.0 in Healthy Adult Female Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2024-12-19
Completion:: 2025-10-08

Conditions

Healthy Volunteer

Interventions

DRUG

No Results Yet

NCT06699212 | RECRUITING | PHASE3

412 participants

A Study of ASP-1929 Photoimmunotherapy in Combination With Pembrolizumab in First-line Treatment of Locoregional Recurrent Squamous Cell Carcinoma of the Head and Neck With No Distant Metastases

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2024-12-24
Completion:: 2028-09-30

Conditions

Recurrent Head and Neck Squamous Cell Carcinoma

Interventions

COMBINATION_PRODUCT
BIOLOGICAL
DRUG

No Results Yet

NCT06662292 | RECRUITING | NA

300 participants

Mobile Supportive Teams for Reinforcing Increased Daily Exercise Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2025-08-28
Completion:: 2027-11-01

Conditions

Physical Activity

Interventions

BEHAVIORAL

No Results Yet

NCT06659744 | COMPLETED

158310 participants

Emulation of the SUSTAIN6 Diabetes Trial Using Healthcare Claims

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-15
Start Date:: 2024-10-24
Completion:: 2025-03-06

Conditions

Diabetes Mellitus, Type 2

Interventions

DRUG

No Results Yet

NCT06611410 | COMPLETED | NA

10 participants

1 Week Crossover Study Between Two Soft Contact Lenses

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2024-06-05
Completion:: 2024-07-26

Conditions

Myopia

Interventions

DEVICE

Results Available

NCT06587659 | COMPLETED | NA

7 participants

Accelerated Image-Guided Robotically Delivered Transcranial Magnetic Stimulation for Combat PTSD

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2025-01-02
Completion:: 2025-07-31

Conditions

Stress Disorders, Post-Traumatic

Interventions

DEVICE

No Results Yet

NCT06555029 | RECRUITING | NA

929 participants

Oral Health Intervention in Adult Primary Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2024-09-25
Completion:: 2028-10-30

Conditions

Dental Caries
Dry Mouth
Periodontal Diseases
Bleeding Gum

Interventions

BEHAVIORAL

No Results Yet

NCT06517459 | RECRUITING | NA

24 participants

Cultural Modification of an Evidence Based Healthy Lifestyle Intervention for People Post Stroke Who Identify as Hispanic/Latino

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2025-05-19
Completion:: 2026-08-31

Conditions

Stroke

Interventions

BEHAVIORAL

No Results Yet

NCT06491914 | ACTIVE_NOT_RECRUITING | PHASE3

1118 participants

A Phase 3b, Single-Arm Study of Aflibercept 8 mg Dosed Every 4 Weeks in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD) or Diabetic Macular Edema (DME)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2024-07-24
Completion:: 2025-08-26

Conditions

Neovascular Age-Related Macular Degeneration
Diabetic Macular Edema

Interventions

DRUG

No Results Yet

NCT06472089 | RECRUITING | NA

800 participants

BMT-CARE: Psychosocial Intervention for Transplant Caregivers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2025-01-10
Completion:: 2028-05-31

Conditions

Bone Marrow Transplant Complications
Hematologic Malignancy

Interventions

BEHAVIORAL

No Results Yet

NCT06463678 | NOT_YET_RECRUITING | PHASE2

60 participants

Trial to Evaluate the Efficacy And Safety of IVIEW-1201 In the Treatment of Fungal Keratitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2026-08-01
Completion:: 2027-12-31

Conditions

Fungal Keratitis

Interventions

DRUG

No Results Yet

NCT06442488 | COMPLETED

14 participants

Wearable Wireless Respiratory Monitoring System That Detects and Predicts Opioid Induced Respiratory Depression

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-15
Start Date:: 2024-05-01
Completion:: 2024-09-30

Conditions

Respiratory Insufficiency
Clinical Deterioration

Interventions

DEVICE

No Results Yet

NCT06355531 | ACTIVE_NOT_RECRUITING | PHASE2

241 participants

A Study to Assess the Efficacy, Safety, and Pharmacokinetics of FNP-223 to Slow Progression of Progressive Supranuclear Palsy (PSP)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2024-07-23
Completion:: 2026-11-30

Conditions

Progressive Supranuclear Palsy

Interventions

DRUG

No Results Yet

NCT06345066 | COMPLETED | PHASE1

96 participants

A Study of LY3841136 in Overweight and Obese Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2024-04-03
Completion:: 2025-09-29

Conditions

Obesity
Overweight

Interventions

DRUG

No Results Yet

NCT06336148 | TERMINATED | PHASE1

10 participants

A Phase 1a/1b Study of ACTM-838 in Patients With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2024-06-05
Completion:: 2025-08-28

Conditions

Solid Tumor

Interventions

DRUG

No Results Yet

NCT06310772 | COMPLETED

60 participants

Assessing Comorbidities in Epilepsy Using Eye Movement Recordings

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-15
Start Date:: 2024-04-15
Completion:: 2025-07-01

Conditions

Childhood Absence Epilepsy
Absence Seizures
Epilepsy Comorbidities

No Results Yet

NCT06307574 | RECRUITING | NA

100 participants

bpMedManage: Digital Technology to Support Adherence to Hypertension Medications

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2024-02-29
Completion:: 2026-04-30

Conditions

Aging
Mild Cognitive Impairment
Hypertension

Interventions

BEHAVIORAL

No Results Yet

NCT06298149 | ENROLLING_BY_INVITATION | NA

200 participants

Reach Through Equitable Implementation of Turtle Island Tales

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2023-11-01
Completion:: 2028-04-30

Conditions

Obesity, Childhood
Obesity
Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06288399 | COMPLETED

1316 participants

Prevalence and Economic Burden of Obesity-related Comorbidities in the Gulf Region: A Retrospective, Observational Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-15
Start Date:: 2023-12-21
Completion:: 2024-09-30

Conditions

Obesity

Interventions

OTHER

No Results Yet

NCT06282510 | RECRUITING | PHASE4

120 participants

Nasal Antisepsis for C. Auris Prevention

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2024-01-29
Completion:: 2026-12-31

Conditions

Candida Auris Infection
Colonization, Asymptomatic

Interventions

DRUG

No Results Yet

NCT06280716 | ACTIVE_NOT_RECRUITING | PHASE3

301 participants

A Study of Lebrikizumab (LY3650150) With/Without Topical Corticosteroid Treatment in Participants With Moderate-to-Severe Atopic Dermatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2024-04-24
Completion:: 2025-09-25

Conditions

Atopic Dermatitis

Interventions

DRUG

No Results Yet

NCT06273163 | TERMINATED | NA

39 participants

Identifying Strategies to Curtail Weight Regain After GLP-1 Receptor Agonist Treatment Cessation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2024-03-05
Completion:: 2025-08-05

Conditions

Obesity

Interventions

OTHER
BEHAVIORAL

No Results Yet

NCT06216366 | ACTIVE_NOT_RECRUITING | PHASE2

36 participants

Rhu-pGSN to Mitigate Proinflammatory Responses to Decompression in Healthy SCUBA Divers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2025-08-15
Completion:: 2025-10-30

Conditions

Decompression Sickness

Interventions

DRUG
OTHER

No Results Yet

NCT06176768 | COMPLETED | PHASE2

33 participants

A Study of LY3972406 in Adult Participants With Moderate-to-Severe Plaque Psoriasis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2023-12-06
Completion:: 2025-04-01

Conditions

Plaque Psoriasis

Interventions

DRUG

Results Available

NCT06174987 | RECRUITING | PHASE3

50 participants

A Study to Provide Continued Access to and Assess Long-Term Safety of the Study Drug(s)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2024-01-05
Completion:: 2026-08-03

Conditions

Advanced Cancer
Metastatic Cancer

Interventions

DRUG

No Results Yet

NCT06169852 | RECRUITING | NA

36 participants

Stimulus-Evoked Directional Field Potentials to Guide Subthalamic and Pallidal DBS for PD

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2024-01-12
Completion:: 2028-11-30

Conditions

Parkinson Disease

Interventions

DEVICE

No Results Yet

NCT06152237 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

6 participants

Safety and Efficacy of TSHA-102 in Pediatric Females With Rett Syndrome (REVEAL Pediatric Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2023-12-12
Completion:: 2028-11-02

Conditions

Rett Syndrome

Interventions

GENETIC

No Results Yet

NCT06150742 | RECRUITING | NA

70 participants

Nafamostat Efficacy in Phase 3 Registrational CRRT Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2024-08-15
Completion:: 2025-12-31

Conditions

Acute Kidney Injury

Interventions

DEVICE

No Results Yet

NCT06141993 | RECRUITING

120 participants

ARCTIC: Liquid Biomarkers in the Prospective Androgen Receptor Signaling Inhibitors (ARSI) Resistance Clinical Trials

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-15
Start Date:: 2024-05-13
Completion:: 2027-04-30

Conditions

Prostate Cancer
Prostate Adenocarcinoma
Prostate Cancer Metastatic
Castration-resistant Prostate Cancer

No Results Yet

NCT06132919 | COMPLETED | PHASE2

33 participants

Efficacy and Safety of MC2-25 Cream & Vehicle in Women With Vulvar Lichen Sclerosus (VLS)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2023-10-11
Completion:: 2024-11-08

Conditions

Vulvar Lichen Sclerosus

Interventions

DRUG

Results Available

NCT06112626 | COMPLETED | NA

1000 participants

Chlorhexidine Gluconate Bathing Education Video Among Hospitalized Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2024-05-01
Completion:: 2025-09-30

Conditions

Infections

Interventions

BEHAVIORAL

No Results Yet

NCT06093490 | COMPLETED

65 participants

Detecting Absence Seizures Using Hyperventilation and Eye Movement Recordings

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-15
Start Date:: 2023-12-01
Completion:: 2025-06-30

Conditions

Absence Epilepsy, Childhood
Absence Seizures
Absence Epilepsy
Epilepsy in Children
Staring
Seizures

Interventions

DEVICE

No Results Yet

NCT06010719 | RECRUITING | PHASE4

3000 participants

Azithromycin as Adjunctive Treatment for Uncomplicated Severe Acute Malnutrition

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2024-10-23
Completion:: 2028-06-30

Conditions

Malnutrition, Child
Severe Acute Malnutrition

Interventions

DRUG
OTHER

No Results Yet

NCT05956665 | COMPLETED | NA

18 participants

Adapting the Shed-MEDS Deprescribing Intervention to Dementia Care in Assisted Living

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2024-01-23
Completion:: 2025-06-27

Conditions

Polypharmacy
Dementia
Quality of Life

Interventions

BEHAVIORAL

Results Available

NCT05932654 | COMPLETED | PHASE2

22 participants

POC Study to Evaluate BSI-045B in Moderate-to-severe Atopic Dermatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2023-07-31
Completion:: 2024-09-18

Conditions

Atopic Dermatitis

Interventions

DRUG

Results Available

NCT05920733 | RECRUITING | NA

120 participants

Healthy Lifetime - Phase 2

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2023-07-05
Completion:: 2026-10-01

Conditions

Aging Well

Interventions

BEHAVIORAL

No Results Yet

NCT05920161 | COMPLETED | NA

106 participants

Influence of Stress on Encoding and Prediction

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2023-03-02
Completion:: 2024-10-04

Conditions

Stress
Learning, Spatial

Interventions

BEHAVIORAL

Results Available

NCT05905783 | TERMINATED | PHASE3

258 participants

Hidradenitis Suppurativa Study of Izokibep

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2023-06-22
Completion:: 2024-07-24

Conditions

Hidradenitis Suppurativa

Interventions

DRUG

Results Available

NCT05846399 | RECRUITING | PHASE4

72 participants

CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2023-09-07
Completion:: 2027-07-01

Conditions

Cat Bite
Hand Injuries
Arm Injury
Infection, Bacterial
Anti-bacterial Agents

Interventions

DRUG
OTHER
PROCEDURE

No Results Yet

NCT05771428 | COMPLETED | PHASE2

263 participants

Study to Assess Adverse Events, Change in Disease Activity and How Oral ABBV-552 Capsules Moves Through the Body of Participants Aged 50 to 90 Years With Mild Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-15
Start Date:: 2023-06-05
Completion:: 2024-08-06

Conditions

Alzheimer's Disease (AD)

Interventions

DRUG

Results Available