Clinical Trials Updated in 2025

NCT07192731 | NOT_YET_RECRUITING | NA

50 participants

International Study on Treatment of Liver (HCC) Patients With IRE

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2026-02-28
Completion:: 2028-02-29

Conditions

Hepatocellular Carcinoma (HCC)
Liver Ablation
Liver Cancer, Adult

Interventions

DEVICE

No Results Yet

NCT07191548 | NOT_YET_RECRUITING | NA

50 participants

International Study on Treatment of Patients With Metastatic Colorectal Liver Lesions Patients With IRE

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2026-02-28
Completion:: 2028-02-29

Conditions

Colorectal Adenocarcinoma Metastatic in the Liver
Liver Ablation
Liver Cancer, Adult

Interventions

DEVICE

No Results Yet

NCT07162363 | NOT_YET_RECRUITING | PHASE2/PHASE3

240 participants

Synergistic Minimally Invasive Surgery and Deferoxamine in ICH

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2026-03-01
Completion:: 2028-12-30

Conditions

Intracerebral Hemorrhage
ICH - Intracerebral Hemorrhage

Interventions

PROCEDURE
DRUG
OTHER

No Results Yet

NCT07141394 | NOT_YET_RECRUITING | NA

7908 participants

Coordinated Access for Addiction Recovery and Equity in VA Supportive Housing

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2026-10-01
Completion:: 2030-09-30

Conditions

Homelessness
Substance Use Disorder (SUD)

Interventions

DRUG
BEHAVIORAL

No Results Yet

NCT07141329 | RECRUITING | PHASE2

100 participants

SPN-817 Open-Label Extension Study in Adults With Focal Onset Seizures

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2025-07-30
Completion:: 2027-12-31

Conditions

Focal Onset Seizures

Interventions

DRUG

No Results Yet

NCT07120763 | RECRUITING | PHASE3

50 participants

Pain Control Alternatives in Pediatric Patients With Distal Radius Fractures

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2025-08-22
Completion:: 2026-08-22

Conditions

Distal Radius Fracture Reduction
Pain Control
Pediatric Fractures

Interventions

DRUG

No Results Yet

NCT07105228 | COMPLETED

290000 participants

Incidence of Retinal Vasculitis Among Patients Receiving Aflibercept: A US Real-World Evidence Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-10
Start Date:: 2025-07-15
Completion:: 2025-08-30

Conditions

Retinal Vasculitis

Interventions

DRUG

No Results Yet

NCT07084363 | RECRUITING | NA

1032 participants

Quantitative Versus qUAlitative NeuromoniToring of neUroMuscular Block for Non-cardiothoracic Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2025-09-22
Completion:: 2026-02-15

Conditions

Neuromuscular Block, Residual

Interventions

DEVICE
OTHER

No Results Yet

NCT07059364 | RECRUITING | NA

32 participants

Empowering Caregivers to Promote Child Independence

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2025-07-15
Completion:: 2026-03-31

Conditions

Profound Autism

Interventions

BEHAVIORAL

No Results Yet

NCT07015398 | COMPLETED | PHASE1

132 participants

A Study of the Pharmacokinetic Interaction Between Pirfenidone, Nintedanib, and Nalbuphine Extended Release (NAL ER) in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2025-06-30
Completion:: 2025-09-12

Conditions

Healthy Participants

Interventions

DRUG

No Results Yet

NCT06948747 | COMPLETED | PHASE1

49 participants

A Study to Investigate the Effect of AZD5004 on Rosuvastatin, Atorvastatin, Simvastatin, Repaglinide and the Effect of Erythromycin on AZD5004 in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2025-05-06
Completion:: 2025-10-03

Conditions

Healthy Participants

Interventions

DRUG

No Results Yet

NCT06814977 | RECRUITING | NA

60 participants

An Acupuncture Study for Cancer Survivors With Joint Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2025-01-31
Completion:: 2028-06-30

Conditions

Cancer Survivor

Interventions

PROCEDURE

No Results Yet

NCT06799169 | ACTIVE_NOT_RECRUITING | PHASE4

100 participants

Management of Acute Tinnitus With Migraine Medications

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2025-06-01
Completion:: 2026-12-31

Conditions

Tinnitus

Interventions

DRUG

No Results Yet

NCT06784193 | RECRUITING | PHASE1

180 participants

Phase 1 Study of OP-3136 in Advanced or Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2024-12-16
Completion:: 2027-05-30

Conditions

Advanced or Metastatic ER+ HER2- Breast Cancer (mBC)
Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Advanced or Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Metastatic Breast Cancer
Fulvestrant
Palazestrant

Interventions

DRUG

No Results Yet

NCT06718582 | COMPLETED | NA

27 participants

Effect of Limb Occlusion Pressure Attainment on Cardiovascular, Perceptual, and Performance Responses

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2025-02-01
Completion:: 2025-04-01

Conditions

Blood Flow Restriction (BFR) Training Effects
Arterial Stiffness, Blood Pressure
Muscle Morphology
Perceptions

Interventions

DEVICE

No Results Yet

NCT06712810 | RECRUITING | PHASE1

46 participants

Q702 for the Treatment of Patients With Hematologic Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2025-08-27
Completion:: 2030-09-15

Conditions

Hematopoietic and Lymphatic System Neoplasm
Histiocytic Sarcoma
Malignant Histiocytosis
Peripheral T-Cell Lymphoma, Not Otherwise Specified
Primary Cutaneous T-Cell Non-Hodgkin Lymphoma
Recurrent Chronic Lymphocytic Leukemia
Recurrent Chronic Myelomonocytic Leukemia
Recurrent Follicular Lymphoma
Recurrent Langerhans Cell Histiocytosis
Recurrent Lymphoplasmacytic Lymphoma
Recurrent Myelodysplastic Syndrome
Recurrent Myelofibrosis
Recurrent Small Lymphocytic Lymphoma
Recurrent Waldenstrom Macroglobulinemia
Refractory Chronic Lymphocytic Leukemia
Refractory Chronic Myelomonocytic Leukemia
Refractory Erdheim-Chester Disease
Refractory Follicular Lymphoma
Refractory Langerhans Cell Histiocytosis
Refractory Lymphoplasmacytic Lymphoma
Refractory Myelodysplastic Syndrome
Refractory Myelofibrosis
Refractory Small Lymphocytic Lymphoma
Refractory Waldenstrom Macroglobulinemia
Rosai-Dorfman-Destombes Disease
Primary Central Nervous System Lymphoma
Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm
Recurrent Erdheim-Chester Disease
Recurrent Fibroblastic Reticular Cell Sarcoma
Recurrent Histiocytic Sarcoma
Recurrent Interdigitating Dendritic Cell Sarcoma
Recurrent Rosai-Dorfman-Destombes Disease
Refractory Blastic Plasmacytoid Dendritic Cell Neoplasm
Refractory Fibroblastic Reticular Cell Sarcoma
Refractory Histiocytic Sarcoma
Refractory Interdigitating Dendritic Cell Sarcoma
Refractory Rosai-Dorfman-Destombes Disease

Interventions

DRUG
PROCEDURE
OTHER

No Results Yet

NCT06687655 | NOT_YET_RECRUITING | PHASE1/PHASE2

30 participants

Impact of Exogenous Ketones on Sleep Apnea

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2026-09-06
Completion:: 2028-09-06

Conditions

Obstructive Sleep Apnea
Sleep

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06636097 | ENROLLING_BY_INVITATION

50 participants

Intaglio Surface of Full-arch Implant Supported Prosthesis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-10
Start Date:: 2024-06-11
Completion:: 2027-12-31

Conditions

Peri-Implantitis

Interventions

DEVICE

No Results Yet

NCT06614712 | COMPLETED

91628 participants

OPTIMISE-CKD Study_current Clinical Landscape in Spain

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-10
Start Date:: 2024-12-04
Completion:: 2025-10-06

Conditions

Renal Disease

Interventions

OTHER

No Results Yet

NCT06547424 | WITHDRAWN | PHASE1

0 participants

Phase I Clinical Study of Chondroitin Sulfate for Treatment of NEC

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2025-01-31
Completion:: 2028-12-31

Conditions

Necrotizing Enterocolitis
Intestinal Ischemia

Interventions

DRUG

No Results Yet

NCT06511388 | TERMINATED

400 participants

Cardiotoxic Effects of Chemotherapy in Patients With Sarcomas: A Two and Three-dimensional Echocardiographic Speckle Tracking Imaging Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-10
Start Date:: 2016-01-20
Completion:: 2024-10-09

Conditions

Sarcoma

Interventions

OTHER

No Results Yet

NCT06447688 | COMPLETED | PHASE4

150 participants

The Role of Verapamil in Radial Artery Spasm

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2024-06-05
Completion:: 2024-11-01

Conditions

Radial Artery Spasm

Interventions

DRUG

Results Available

NCT06445543 | WITHDRAWN | NA

0 participants

Nutrition Optimization and Community Upliftment for Postpartum Recovery: Hypertension

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2026-09-30
Completion:: 2027-03-31

Conditions

Obesity, Maternal
Pre-Eclampsia; Complicating Pregnancy
Gestational Hypertension
Eclampsia; Complicating Pregnancy

Interventions

BEHAVIORAL

No Results Yet

NCT06433661 | COMPLETED | PHASE1

16 participants

A Research Study of the Effect of Food on Etavopivat in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2024-05-28
Completion:: 2024-07-06

Conditions

Healthy Volunteers Sickle Cell Disease, Thalassemia

Interventions

DRUG

No Results Yet

NCT06372782 | COMPLETED | NA

90 participants

Comparing Pain, Safety and Effectiveness of Restylane Skinboosters Vital Lido and Vital Without Lido in Dorsal Hand

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2024-04-24
Completion:: 2024-06-28

Conditions

Skin Aging of Dorsal Hands

Interventions

DEVICE

Results Available

NCT06312462 | COMPLETED | NA

978 participants

Health Education Model Led by Community Health Volunteers.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2024-02-24
Completion:: 2025-02-28

Conditions

Schistosomiasis
Health Education

Interventions

BEHAVIORAL

Results Available

NCT06310759 | RECRUITING

3000 participants

Prospective Validation Study of High Volume Urine DNA Testing in Individuals With Suspicion of Urothelial Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-10
Start Date:: 2024-01-08
Completion:: 2026-12-31

Conditions

Urothelial Carcinoma

No Results Yet

NCT06236815 | COMPLETED | EARLY_PHASE1

5 participants

High Confusion: Cannabis & Driving

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2025-01-25
Completion:: 2025-09-16

Conditions

Impairment, Cognitive
Impairment of Attention
Impairment, Psychomotor

Interventions

DRUG

No Results Yet

NCT06203002 | COMPLETED | PHASE2

496 participants

A Dose-ranging Study in Patients With Diabetic Peripheral Neuropathic Pain (DPNP)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2023-11-29
Completion:: 2025-01-14

Conditions

Diabetic Peripheral Neuropathic Pain

Interventions

DRUG

No Results Yet

NCT06112093 | RECRUITING | PHASE1

60 participants

Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2023-10-23
Completion:: 2026-10-23

Conditions

Brain Concussion
Mild Traumatic Brain Injury
Headache
Post-Concussion Symptoms

Interventions

DEVICE

No Results Yet

NCT06077838 | RECRUITING | NA

356 participants

RELAXaHEAD for Headache Patients (Phase III)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2023-11-08
Completion:: 2028-08-31

Conditions

Migraine

Interventions

BEHAVIORAL

No Results Yet

NCT05948826 | ACTIVE_NOT_RECRUITING | PHASE1

70 participants

First in Human Study of TORL-3-600 in Participants With Advanced Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2023-09-29
Completion:: 2026-06-25

Conditions

Advanced Solid Tumor
Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT05945927 | COMPLETED

178 participants

A Study to Evaluate the Safety and Effectiveness of Trastuzumab Emtansine (T-DM1) as Therapy in Chinese Participants With HER2 Positive Advanced Breast Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-10
Start Date:: 2023-09-13
Completion:: 2025-08-30

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet

NCT05931393 | RECRUITING | PHASE2

18 participants

Sequential Treatment of Cabozantinib for Advanced Renal Cell Carcinoma (RCC)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2023-12-20
Completion:: 2026-09-01

Conditions

RCC
Renal Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT05910749 | WITHDRAWN | NA

0 participants

Substance Use Disorder, Brain and Behavioral Regulation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2025-04-01
Completion:: 2026-03-31

Conditions

Substance Use Disorders

Interventions

DEVICE

No Results Yet

NCT05815199 | RECRUITING | NA

60 participants

E-cigarettes for Harm Reduction Among Smokers With Serious Mental Illness

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2023-11-13
Completion:: 2026-03-31

Conditions

Cigarette Smoking

Interventions

OTHER
BEHAVIORAL

No Results Yet

NCT05729373 | COMPLETED | PHASE2/PHASE3

434 participants

A Clinical Study That Will Measure How Well SEP-363856 Works and How Safe it is in Adults With Generalized Anxiety Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2023-03-08
Completion:: 2025-09-26

Conditions

Generalized Anxiety Disorder

Interventions

DRUG

No Results Yet

NCT05695846 | WITHDRAWN | NA

0 participants

Diagnostic Tests in Supra-Esophageal Gastroesophageal Reflux Disease (SE-GERD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2014-01-29
Completion:: 2025-04-02

Conditions

Gastroesophageal Reflux

Interventions

DEVICE

No Results Yet

NCT05622604 | COMPLETED | NA

312 participants

The Effect of Religious Practices on Mental and Spiritual Health

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2022-11-30
Completion:: 2023-03-10

Conditions

Stress

Interventions

BEHAVIORAL

Results Available

NCT05540392 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

60 participants

An Acupuncture Study for Prostate Cancer Survivors With Urinary Issues

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-10
Start Date:: 2022-09-09
Completion:: 2026-09-30

Conditions

Survivorship
Prostate Cancer

Interventions

PROCEDURE
OTHER

No Results Yet