Clinical Trials Updated in 2025

NCT06572800 | COMPLETED | NA

34 participants

Tka Assay for CDK4/6i

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2023-09-05
Completion:: 2025-09-16

Conditions

Anatomic Stage IV Breast Cancer AJCC v8
Metastatic HER2-Negative Breast Carcinoma

Interventions

DEVICE

No Results Yet

NCT06386432 | WITHDRAWN | NA

0 participants

EQQUAL-NM for the Promotion of Smoking Cessation in Sexual and Gender Minority Young Adults in New Mexico

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2025-12-01
Completion:: 2026-04-01

Conditions

Cigarette Smoking-Related Carcinoma

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06353971 | TERMINATED | PHASE1/PHASE2

27 participants

A Dose Escalation Trial of Safety, Pharmacokinetic/Pharmacodynamic and Preliminary Clinical Activity of Briquilimab in Adult Patients With Chronic Inducible Urticaria (CIndU) Who Remain Symptomatic Despite Treatment With H1- Antihistamines

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2024-03-18
Completion:: 2025-07-31

Conditions

Chronic Inducible Urticaria

Interventions

DRUG

No Results Yet

NCT06315309 | RECRUITING | PHASE2

29 participants

Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2025-04-15
Completion:: 2026-12-31

Conditions

GVHD,Acute
Acute Leukemia
Myelodysplastic Syndromes
Myeloproliferative Disorders

Interventions

DRUG

No Results Yet

NCT06310213 | ENROLLING_BY_INVITATION | NA

25 participants

Non-Invasive Pressure Monitor for Neonates & Infants at Risk of Developing Hydrocephalus

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2025-01-24
Completion:: 2029-01-01

Conditions

Hydrocephalus in Infants

Interventions

DEVICE

No Results Yet

NCT06265584 | RECRUITING | PHASE2

56 participants

Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell Transplant

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2025-04-08
Completion:: 2028-08-31

Conditions

Acute Leukemia
Myelodysplastic Syndrome
Myeloproliferative Disorders

Interventions

DRUG

No Results Yet

NCT06250985 | RECRUITING | PHASE3

176 participants

New Treatment of Cardiac Device Infections; Immediate Reimplantation After Removal of Infected System

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2024-04-29
Completion:: 2027-12-31

Conditions

Endocarditis, Bacterial

Interventions

OTHER

No Results Yet

NCT06208605 | RECRUITING | NA

320 participants

Innovations in Personalizing Treatment Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2024-01-21
Completion:: 2028-08-31

Conditions

Eating Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT06180460 | COMPLETED | NA

60 participants

CALM: Managing Distress in Malignant Brain Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2023-11-10
Completion:: 2025-09-30

Conditions

Brain Tumor
Brain Metastases
Brain Cancer
Metastatic Lung Cancer
Metastatic Breast Cancer
Metastatic Melanoma
Metastatic Colon Cancer
Metastatic Kidney Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06157879 | COMPLETED | NA

50 participants

Measuring Electrical Properties of Breast Tissues

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2024-05-27
Completion:: 2024-11-18

Conditions

Healthy
Breast

Interventions

DEVICE

No Results Yet

NCT06059690 | RECRUITING | PHASE1/PHASE2

50 participants

Biologic Association Between Metabolic Magnetic Resonance-positron Emission Tomograph (MR-PET) and Tissue Measures of Glycolysis in Brain Tumors of Infiltrating Glioblastoma Cells

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2023-09-06
Completion:: 2027-09-30

Conditions

Glioblastoma Multiforme
Glycolytic Index
Epidermal Growth Factor Receptor

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06029959 | COMPLETED | NA

36 participants

Stroke and CPAP Outcome Study 3

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2023-10-01
Completion:: 2024-09-30

Conditions

Ischemic Stroke
Intra Cerebral Hemorrhage
Obstructive Sleep Apnea
Adherence, Treatment
Motivation

Interventions

DEVICE
BEHAVIORAL

Results Available

NCT06005597 | COMPLETED | PHASE3

407 participants

Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2024-03-01
Completion:: 2024-09-25

Conditions

Dyslipidemias
Hypercholesterolemia
Familial Hypercholesterolemia
ASCVD
High Cholesterol

Interventions

COMBINATION_PRODUCT
DRUG
OTHER

Results Available

NCT06004986 | RECRUITING | PHASE4

216 participants

DUPIlumab Dose REDUCtion in Patients With Controlled Atopic Eczema

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2023-08-14
Completion:: 2025-10-01

Conditions

Atopic Dermatitis
Atopic Dermatitis Eczema

Interventions

DRUG

No Results Yet

NCT05980546 | COMPLETED | PHASE4

244 participants

Genicular and Anterior Femoral Cutaneous Nerve Blocks for Total Knee Arthroplasty

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2023-06-07
Completion:: 2025-09-05

Conditions

Total Knee Replacement
Genicular Nerve Block
Opioid Use

Interventions

DRUG

No Results Yet

NCT05940948 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated:: 2025-10-08

No Results Yet

NCT05904769 | TERMINATED | NA

87 participants

A Study of Non-invasive Measurement of Blood Glucose and Blood Pressure

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2023-05-31
Completion:: 2024-04-30

Conditions

Diabetes

Interventions

DEVICE

Results Available

NCT05901233 | ENROLLING_BY_INVITATION | NA

10 participants

Speech-Language Treatment With Remotely Supervised Transcranial Direct Current Stimulation in Primary Progressive Aphasia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2023-07-10
Completion:: 2026-08-30

Conditions

Primary Progressive Aphasia

Interventions

DEVICE
BEHAVIORAL

No Results Yet

NCT05852457 | RECRUITING

250 participants

Evaluation of the Clinical Utility of Endoscopic Closure Using a Dual Action Tissue (DAT) Clip

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-08
Start Date:: 2022-08-31
Completion:: 2027-08-31

Conditions

GI Bleeding
Perforation Colon
Perforation Bowel
Perforation Duodenal
Perforated Bowel
Fistula

Interventions

DEVICE

No Results Yet

NCT05640947 | RECRUITING | NA

20 participants

Endoscopic Ultrasound-guided Large Diameter Lumen-apposing Metal Stent Gastro-gastrostomy for Bypass Reversal in Patients With Roux-en-y Gastric Bypass

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2023-01-30
Completion:: 2027-10-31

Conditions

Hypoglycemia
Gastric Outlet Obstruction
Steatohepatitis
Parenteral Support
Gastric Bypass

Interventions

DEVICE

No Results Yet

NCT05611996 | COMPLETED | NA

34 participants

PEERS Plus mHealth Enhanced Peer Support

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2022-12-15
Completion:: 2025-01-17

Conditions

Depression in Old Age

Interventions

BEHAVIORAL

Results Available

NCT05599269 | COMPLETED | NA

17 participants

Retrospective Clinical Evaluation of Nano-hybrid-composite Denture Teeth

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2022-11-18
Completion:: 2023-04-11

Conditions

Edentulous Mouth
Dental Prosthesis Failure

Interventions

DEVICE

Results Available

NCT05560763 | COMPLETED | NA

50 participants

FlowTriever2 Pulmonary Embolectomy Clinical Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2023-02-14
Completion:: 2024-09-09

Conditions

Pulmonary Embolism

Interventions

DEVICE

Results Available

NCT05524493 | RECRUITING

200 participants

High-field MR Imaging in Migraine, Visual Snow and Epilepsy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-08
Start Date:: 2025-03-01
Completion:: 2026-06-30

Conditions

Migraine
Epilepsy
Visual Snow Syndrome

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05461573 | COMPLETED | PHASE3

1542 participants

Efficacy, Safety, and Tolerability of LPRI-CF113 as an Oral Contraceptive in Females

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2022-08-02
Completion:: 2024-08-05

Conditions

Contraception
Change in Bone Mineral Density

Interventions

DRUG

No Results Yet

NCT05420012 | COMPLETED | PHASE4

26 participants

The Effect of Vericiguat on Peripheral Vascular Function, Patient Health Status and Inflammation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2023-05-01
Completion:: 2024-10-24

Conditions

Heart Failure
Heart Failure With Reduced Ejection Fraction (HFrEF)

Interventions

DRUG

Results Available

NCT05418244 | RECRUITING | PHASE2/PHASE3

84 participants

Inhaled Isopropyl Alcohol for Treatment of Nausea

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2022-04-20
Completion:: 2026-06-30

Conditions

Vomiting
Nausea
Children, Only

Interventions

OTHER
DRUG

No Results Yet

NCT05321719 | COMPLETED | NA

228 participants

Multi-Media Parent-based Intervention to Promote Dental Hygiene Among Young Children: BeReady2Smile II

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2023-04-10
Completion:: 2024-04-24

Conditions

Plaque

Interventions

BEHAVIORAL

No Results Yet

NCT05317078 | TERMINATED | PHASE1

3 participants

A Phase 1 Safety, Tolerability, and Pharmacokinetics Study of AMG 794 With Claudin 6-positive Non-small Cell Lung Cancer, Epithelial Ovarian Cancer, and Other Malignant Solid Tumor Indications

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2023-02-28
Completion:: 2023-12-19

Conditions

Non-squamous Non-small Cell Lung Cancer
Epithelial Ovarian Cancer
Claudin 6-positive Advanced/Metastatic Malignant Solid Tumors

Interventions

DRUG

No Results Yet

NCT05307328 | COMPLETED | PHASE2

26 participants

SPI-62 as a Treatment for Adrenocorticotropic Hormone-dependent Cushing's Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2022-09-01
Completion:: 2025-08-01

Conditions

Cushing's Syndrome I
Cushing Disease Due to Increased ACTH Secretion
Cortisol Excess
Cortisol; Hypersecretion
Cortisol Overproduction
Ectopic ACTH Secretion

Interventions

DRUG

No Results Yet

NCT05245201 | ACTIVE_NOT_RECRUITING | NA

4 participants

Clinical Decision Support for PrEP

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2022-07-11
Completion:: 2026-08-31

Conditions

HIV Infections
Preexposure Prophylaxis (PrEP)

Interventions

OTHER

No Results Yet

NCT05236192 | COMPLETED | NA

341 participants

New Parent Support Program Evaluation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2023-02-17
Completion:: 2025-08-07

Conditions

Child Maltreatment

Interventions

BEHAVIORAL

No Results Yet

NCT05206331 | RECRUITING | PHASE4

2100 participants

CEM to Reduce Biopsy Rates for Less Than Highly Suspicious Breast Abnormalities: a Prospective Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2022-02-01
Completion:: 2026-11-30

Conditions

Breast Cancer

Interventions

DEVICE
DRUG

No Results Yet

NCT05101746 | ENROLLING_BY_INVITATION | PHASE2/PHASE3

50 participants

Nitric Oxide Effect on Brain and Kidney in Pediatric Patients Undergoing Cardiopulmonary Bypass

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2022-04-25
Completion:: 2026-09-30

Conditions

Congenital Heart Disease
Congenital Heart Defect
Congenital Heart Malformations

Interventions

DRUG
OTHER

No Results Yet

NCT05084521 | COMPLETED | PHASE2/PHASE3

30 participants

Interest of Famotidine in Children With Sickle Cell Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2022-01-12
Completion:: 2022-12-12

Conditions

Sickle Cell Disease

Interventions

DRUG

No Results Yet

NCT05027789 | ACTIVE_NOT_RECRUITING | NA

263 participants

Brain Boosters 2 in Persons at Risk for Alzheimer's Disease: a Digital Application Supported Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2021-08-13
Completion:: 2026-08-31

Conditions

Memory Disorders
Cognitive Impairment

Interventions

BEHAVIORAL

No Results Yet

NCT04967274 | RECRUITING | NA

248 participants

Reticulospinal Control of Movements

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2022-01-15
Completion:: 2026-06-30

Conditions

Spinal Cord Injuries
Healthy

Interventions

PROCEDURE

No Results Yet

NCT04932447 | ACTIVE_NOT_RECRUITING | NA

122 participants

Breathing Training for Improving Cardiovascular Health in Older Adults With Sleep Apnea

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2021-09-01
Completion:: 2026-06-30

Conditions

Obstructive Sleep Apnea
Hypertension

Interventions

BEHAVIORAL

No Results Yet

NCT04888312 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

94 participants

Safety and Efficacy of Mitazalimab in Combination With Chemotherapy in Pancreatic Cancer Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2021-09-17
Completion:: 2026-06-01

Conditions

Metastatic Pancreatic Ductal Adenocarcinoma

Interventions

BIOLOGICAL

No Results Yet

NCT04859699 | COMPLETED | NA

1095 participants

Reopening Schools Safely and Educating Youth Research Study (ROSSEY)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-08
Start Date:: 2022-01-17
Completion:: 2024-05-08

Conditions

Absenteeism

Interventions

BEHAVIORAL

Results Available