Clinical Trials

NCT05882357 | COMPLETED | PHASE3

70 participants

Evaluation of Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) in Cystic Fibrosis (CF) Participants 12 to Less Than 24 Months of Age

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2023-06-27

Completion:

2025-09-04

Conditions

• Cystic Fibrosis

Interventions

• DRUG

No Results Yet

NCT05879991 | COMPLETED | PHASE1

15 participants

A Study in Healthy Men to Test How Zongertinib (BI 1810631) is Taken up and Processed by the Body

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2023-08-10

Completion:

2023-10-19

Conditions

• Healthy

Interventions

• DRUG

Results Available

NCT05869682 | RECRUITING | PHASE2

210 participants

Bright White Light Therapy in Reducing Cancer-Related Fatigue and Depression in Advanced Prostate Cancer Patients Undergoing Treatment With ADT Combination Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2024-07-09

Completion:

2028-11-30

Conditions

• Advanced Prostate Carcinoma
• Metastatic Prostate Carcinoma
• Prostate Carcinoma
• Stage III Prostate Cancer AJCC v8
• Stage IV Prostate Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG
• OTHER

No Results Yet

NCT05856539 | RECRUITING | NA

48 participants

ESP Block in MIS Lumbar Spine Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2023-05-15

Completion:

2026-07-15

Conditions

• Patients With Spinal Stenosis Indicated for MIS TLIF

Interventions

• PROCEDURE

No Results Yet

NCT05837923 | COMPLETED | NA

2016 participants

Radicle Relief 2: A Study of Health and Wellness Products on Pain and Health Outcomes

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2024-05-28

Completion:

2024-07-17

Conditions

• Pain
• Neuropathic Pain
• Nociceptive Pain

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT05834998 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated:

2025-10-06

No Results Yet

NCT05832879 | COMPLETED | NA

33 participants

Telehealth Treatment for Opioid Use Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2024-05-01

Completion:

2025-07-24

Conditions

• Opioid Use Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT05832138 | NOT_YET_RECRUITING | NA

900 participants

ONLOOP Trial: Evaluating a New Surveillance and Support System for Survivors of Childhood Cancer in Ontario

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2025-10-31

Completion:

2027-11-30

Conditions

• Survivorship
• Cancer
• Heart Diseases
• Secondary Cancer
• Colorectal Cancer
• Breast Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT05804851 | ACTIVE_NOT_RECRUITING

237 participants

Skin Microbiome of Chinese Population Cohort Study

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-06

Start Date:

2023-05-08

Completion:

2025-12-31

Conditions

• Skin Microbiome

No Results Yet

NCT05762367 | COMPLETED | NA

40 participants

MR Lymphatic Imaging in Idiopathic Intracranial Hypertention

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2023-03-10

Completion:

2025-04-11

Conditions

• Idiopathic Intracranial Hypertension

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05734560 | RECRUITING | PHASE1/PHASE2

50 participants

D2C7-IT and 2141-V11 in Newly Diagnosed GBM Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2023-09-06

Completion:

2026-10-31

Conditions

• Newly Diagnosed MGMT Unmethylated Glioblastoma

Interventions

• DRUG

No Results Yet

NCT05716945 | RECRUITING | PHASE4

342 participants

The OPTIMISE Study

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2024-07-29

Completion:

2028-09-30

Conditions

• Pseudophakic Bullous Keratopathy
• Fuchs' Endothelial Dystrophy
• Intraocular Pressure

Interventions

• DRUG
• OTHER

No Results Yet

NCT05699772 | ACTIVE_NOT_RECRUITING | NA

85 participants

Expanding Delivery of an Evidence-based Weight-loss Intervention to Enhance Access and Reach Underserved Groups After TBI

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2023-05-25

Completion:

2026-08-31

Conditions

• Traumatic Brain Injury

Interventions

• BEHAVIORAL

No Results Yet

NCT05675527 | RECRUITING | PHASE4

135 participants

PRP for Glenohumeral Osteoarthritis

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2023-05-02

Completion:

2026-09-01

Conditions

• Shoulder Osteoarthritis

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT05672927 | RECRUITING | PHASE4

618 participants

Comparing Immune Response of 2 vs 3 HPV Doses (27-45 Years Old)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2023-01-18

Completion:

2026-08-31

Conditions

• Immunization
• HPV Infection
• Human Papillomavirus

Interventions

• BIOLOGICAL

No Results Yet

NCT05672381 | COMPLETED

15 participants

NIRST and ICG-based Perfusion Imaging in Acute Compartment Syndrome

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-06

Start Date:

2023-05-12

Completion:

2025-09-16

Conditions

• Compartment Syndromes
• Compartment Syndrome of Lower Leg
• Compartment Syndrome of Forearm

Interventions

• PROCEDURE

No Results Yet

NCT05624359 | SUSPENDED | NA

216 participants

Flurbiprofen Axetil as an Adjuvant to Pre-emptive Scalp Infiltration

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2023-11-01

Completion:

2026-03-01

Conditions

• Postoperative Pain

Interventions

• DRUG

No Results Yet

NCT05599334 | COMPLETED

111 participants

A Retrospective Observational Study of Patients With Early-stage HER2-positive Breast Cancer, Treated With Neratinib

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-06

Start Date:

2022-07-05

Completion:

2023-01-30

Conditions

• Breast Cancer
• Adjuvant Therapy
• HER2-positive Breast Cancer

Results Available

NCT05591924 | RECRUITING

1000 participants

Early Severe Illness TrAnslational BioLogy InformaticS in Humans

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-06

Start Date:

2024-04-26

Completion:

2034-12-31

Conditions

• Sepsis
• ARDS
• Critical Illness
• Neurocognitive Dysfunction
• Shock, Septic
• Ventilator Associated Pneumonia
• Immune Suppression
• Inflammation
• SIRS

Interventions

• PROCEDURE

No Results Yet

NCT05589155 | RECRUITING | NA

30 participants

Efficacy of Using Mobile Health Applications for Health

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2022-10-01

Completion:

2028-07-01

Conditions

• Diabetes Mellitus, Type 2
• Obesity

Interventions

• OTHER

No Results Yet

NCT05571696 | COMPLETED | NA

84 participants

Mind Matters: A High Touch, Low Cost Approach to Improving Mental Health Outcomes in Patients With Psoriatic Diseases

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2022-10-27

Completion:

2025-03-31

Conditions

• Arthritis, Psoriatic
• Psoriasis

Interventions

• BEHAVIORAL

No Results Yet

NCT05571319 | COMPLETED | PHASE2

30 participants

A Pilot Study of Metformin to Reduce Cerebrovascular Dysfunction in Participants With HIV and Metabolic Syndrome.

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2022-08-11

Completion:

2025-03-24

Conditions

• Metabolic Syndrome
• HIV Seropositivity

Interventions

• DRUG

No Results Yet

NCT05558059 | RECRUITING

16 participants

Imaging Retinal Vasculature in Infant Eyes

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-06

Start Date:

2024-10-03

Completion:

2027-08-31

Conditions

• Retinopathy of Prematurity

Interventions

• DEVICE

No Results Yet

NCT05513378 | COMPLETED | NA

300 participants

Ultrasound-guided Subclavian Vein Catheterisation With a Needle Guide

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2022-11-08

Completion:

2025-09-16

Conditions

• Complications; Catheter, Mechanical
• Catheterization, Central Venous

Interventions

• DEVICE

No Results Yet

NCT05507333 | COMPLETED | NA

26 participants

Clinical Performance of the Gedea Pessary in Adult Women With Vulvovaginal Candidiasis

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2023-03-16

Completion:

2024-02-22

Conditions

• Vulvovaginal Candidiasis

Interventions

• DEVICE

Results Available

NCT05484635 | RECRUITING | NA

70 participants

Mesh Removal Versus No Mesh Removal for Chronic Groin Pain After Inguinal Hernia Repair

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2022-07-25

Completion:

2027-12-31

Conditions

• Chronic Groin Pain
• Hernia, Inguinal

Interventions

• PROCEDURE

No Results Yet

NCT05464069 | COMPLETED

145 participants

Safety of Nerivio in Pregnant Women With Migraine

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-06

Start Date:

2022-08-01

Completion:

2022-11-28

Conditions

• Migraine
• Pregnancy Related

Interventions

• DEVICE
• DRUG

Results Available

NCT05443568 | COMPLETED

155 participants

A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Israel, as Part of Local Clinical Practice

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-06

Start Date:

2023-03-09

Completion:

2024-11-16

Conditions

• Diabetes Mellitus, Type 2

Interventions

• DRUG

No Results Yet

NCT05428345 | RECRUITING

600 participants

A Study of Vedolizumab SC Given to Adults With Moderate to Severe Ulcerative Colitis or Crohn's Disease in South Korea

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-06

Start Date:

2023-09-25

Completion:

2027-11-30

Conditions

• Ulcerative Colitis
• Crohn's Disease
• Inflammatory Bowel Disease (IBD)

No Results Yet

NCT05379322 | WITHDRAWN | PHASE3

0 participants

The Use of Synovial Biopsies in Predicting Response to Biologic Therapy in Rheumatoid Arthritis Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2023-03-01

Completion:

2023-03-01

Conditions

• Rheumatoid Arthritis

Interventions

• DRUG

No Results Yet

NCT05377034 | RECRUITING | PHASE2

100 participants

Multinational Phase II Trial to Compare Safety and Efficacy of SIRT (Y-90 Resin Microspheres) Followed by Atezolizumab Plus Bevacizumab, vs SIRT (SIRT-Y90) Followed by Placebo in Locally Advanced HCC Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2022-10-26

Completion:

2026-07-25

Conditions

• Locally Advanced Hepatocellular Carcinoma

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT05365958 | COMPLETED | NA

128 participants

Podcasting HIV Prevention Within African American Communities

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2022-02-11

Completion:

2023-10-31

Conditions

• HIV Prevention

Interventions

• BEHAVIORAL

Results Available

NCT05361031 | COMPLETED | PHASE1/PHASE2

12 participants

The Safety and Tolerability of Engensis (VM202) in Patients With Charcot-Marie-Tooth Disease Subtype 1A (CMT1A)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2020-09-21

Completion:

2021-09-09

Conditions

• CMT

Interventions

• BIOLOGICAL

Results Available

NCT05313334 | TERMINATED | NA

50 participants

GAMBIT Task With PTSD and Healthy Control Participants

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2022-11-18

Completion:

2024-10-29

Conditions

• Posttraumatic Stress Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT05308966 | COMPLETED

204 participants

Observational Study in Patients With Previously Unresectable Malignant Pleural Mesothelioma Treated With Nivolumab and Ipilimumab (MESO-IMMUNE)

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-06

Start Date:

2022-05-03

Completion:

2025-08-27

Conditions

• Malignant Pleural Mesothelioma
• Unresectable Malignant Neoplasm

Interventions

• OTHER

No Results Yet

NCT05284747 | ACTIVE_NOT_RECRUITING | PHASE4

6019 participants

EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2022-10-26

Completion:

2027-05-29

Conditions

• Cardiovascular Disease
• Myocardial Infarction
• Stroke
• Coronary Revascularization

Interventions

• DRUG

No Results Yet

NCT05279729 | RECRUITING | NA

45 participants

Efficacy of mHealth Apps for Health in a Low-income, Type II Diabetic, Hispanic Population

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2022-08-01

Completion:

2028-10-31

Conditions

• Diabetes Mellitus, Type 2
• Obesity

Interventions

• OTHER

No Results Yet

NCT05244928 | COMPLETED | NA

131 participants

Team Training and Medication Administration in an Ambulance Service

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2022-01-24

Completion:

2024-01-31

Conditions

• Patient Safety
• Medication Administration

Interventions

• OTHER

No Results Yet

NCT05224505 | ACTIVE_NOT_RECRUITING | PHASE1

6 participants

ATA-100 (Formerly GNT0006) Gene Therapy Trial in Patients With LGMDR9

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2022-09-01

Completion:

2025-02-01

Conditions

• LGMDR9

Interventions

• BIOLOGICAL

No Results Yet

NCT05220865 | COMPLETED | NA

268 participants

Hall Technique or Modified Hall Technique of Deep Carious Lesions in Primary Molars

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-06

Start Date:

2022-02-01

Completion:

2023-09-01

Conditions

• Dental Caries in Children
• Tooth Diseases
• Tooth Demineralization
• Stomatognathic Diseases

Interventions

• PROCEDURE

No Results Yet