Clinical Trials Updated in 2025

NCT06168305 | ENROLLING_BY_INVITATION

1000 participants

Safety and Effectiveness of GENOSS® DES in Patients With Multivessel Coronary Artery Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-11-15
Completion:: 2028-02-28

Conditions

Percutaneous Coronary Intervention
Multivessel Coronary Artery Disease

Interventions

DEVICE

No Results Yet

NCT06158022 | COMPLETED | NA

60 participants

ED90 of Norepinephrine and Phenylephrine Infusions in Preeclamptic Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-10-03
Completion:: 2025-05-20

Conditions

Adverse Effect

Interventions

DRUG

No Results Yet

NCT06140498 | COMPLETED | NA

93 participants

Effects of Self-Efficacy Ecological Momentary Intervention (EMA) App

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2021-11-01
Completion:: 2022-12-15

Conditions

Self Efficacy

Interventions

BEHAVIORAL

No Results Yet

NCT06129994 | COMPLETED

47 participants

Ecological Momentary Assessment Study of Adolescents and Young Adults With Type 1 Diabetes (EMA-T1D)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-11-07
Completion:: 2025-08-10

Conditions

Type 1 Diabetes

Interventions

OTHER

No Results Yet

NCT06114628 | RECRUITING | PHASE2

2500 participants

Platform Assessing Regimens and Durations In a Global Multisite Consortium for TB

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-01-09
Completion:: 2027-02-24

Conditions

Pulmonary Tuberculosis

Interventions

DRUG

No Results Yet

NCT06086496 | ENROLLING_BY_INVITATION

1000 participants

Effectiveness and Safety of Abluminal Biodegradable Polymer Sirolimus-eluting Stent (GENOSS® DES)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2022-07-15
Completion:: 2027-12-31

Conditions

Coronary Artery Disease
Percutaneous Coronary Intervention

Interventions

DEVICE

No Results Yet

NCT06077383 | COMPLETED | NA

72 participants

Effect of Weizmania Coagulans BC99 Intervention on Gut Microbiota and Metabolic Markers in Overweight/Obese Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-10-25
Completion:: 2024-07-30

Conditions

Overweight

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06074861 | COMPLETED | NA

28 participants

Fasting-mimicking Diet and Periodontitis (FMD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-12-04
Completion:: 2024-04-26

Conditions

Periodontal Disease, AVDC Stage 3
Periodontal Disease, AVDC Stage 4
Periodontitis

Interventions

PROCEDURE

No Results Yet

NCT06055036 | RECRUITING | NA

340 participants

Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-08-24
Completion:: 2026-03-31

Conditions

Cardiometabolic Syndrome
Physical Inactivity
Hypertension
Type 2 Diabetes
PreDiabetes
Obesity
Cardiovascular Diseases
Smoking
Sleep
Hyperlipidemias
Diet, Healthy
Blood Pressure

Interventions

BEHAVIORAL

No Results Yet

NCT06052826 | RECRUITING | PHASE2

164 participants

Geriatric Assessment Guided Interventions to Accelerate Functional Recovery After CAR-T Therapy for Patients 60 Years and Older With B-cell Non-Hodgkin Lymphoma or Multiple Myeloma, GOCART Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-06-23
Completion:: 2026-10-05

Conditions

B-Cell Non-Hodgkin Lymphoma
Multiple Myeloma

Interventions

OTHER
PROCEDURE

No Results Yet

NCT06029309 | RECRUITING | PHASE1/PHASE2

27 participants

Zanubrutinib and Tafasitamab in Mantle Cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-05-03
Completion:: 2028-05-01

Conditions

Mantle Cell Lymphoma

Interventions

DRUG

No Results Yet

NCT06022965 | RECRUITING | NA

216 participants

Telemedicine for Improvement of Care for Older Adults With Cancer in the Underserved Community, The GAIN-S Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-07-24
Completion:: 2027-01-24

Conditions

Hematopoietic and Lymphoid System Neoplasm
Malignant Solid Neoplasm

Interventions

OTHER

No Results Yet

NCT05976334 | TERMINATED | PHASE1

3 participants

An Absorption, Distribution, Metabolism, Excretion (ADME) Study of [14C]Subasumstat in Adults With Advanced or Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-11-14
Completion:: 2024-06-21

Conditions

Solid Tumors

Interventions

DRUG

Results Available

NCT05974488 | RECRUITING | NA

50 participants

The Efficacy of Distal Pharyngeal Airway for Oxygenation During TEE

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-11-30
Completion:: 2026-10-01

Conditions

Airway Obstruction

Interventions

DEVICE

No Results Yet

NCT05887089 | WITHDRAWN

0 participants

Analytical Impact of the Transport of Pathological Biological Material by Drone

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-05-22
Completion:: 2023-09-30

Conditions

Biological Samples

Interventions

OTHER

No Results Yet

NCT05882357 | COMPLETED | PHASE3

70 participants

Evaluation of Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) in Cystic Fibrosis (CF) Participants 12 to Less Than 24 Months of Age

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-06-27
Completion:: 2025-09-04

Conditions

Cystic Fibrosis

Interventions

DRUG

No Results Yet

NCT05879991 | COMPLETED | PHASE1

15 participants

A Study in Healthy Men to Test How Zongertinib (BI 1810631) is Taken up and Processed by the Body

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-08-10
Completion:: 2023-10-19

Conditions

Healthy

Interventions

DRUG

Results Available

NCT05869682 | RECRUITING | PHASE2

210 participants

Bright White Light Therapy in Reducing Cancer-Related Fatigue and Depression in Advanced Prostate Cancer Patients Undergoing Treatment With ADT Combination Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-07-09
Completion:: 2028-11-30

Conditions

Advanced Prostate Carcinoma
Metastatic Prostate Carcinoma
Prostate Carcinoma
Stage III Prostate Cancer AJCC v8
Stage IV Prostate Cancer AJCC v8

Interventions

PROCEDURE
DRUG
OTHER

No Results Yet

NCT05856539 | RECRUITING | NA

48 participants

ESP Block in MIS Lumbar Spine Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-05-15
Completion:: 2026-07-15

Conditions

Patients With Spinal Stenosis Indicated for MIS TLIF

Interventions

PROCEDURE

No Results Yet

NCT05837923 | COMPLETED | NA

2016 participants

Radicle Relief 2: A Study of Health and Wellness Products on Pain and Health Outcomes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-05-28
Completion:: 2024-07-17

Conditions

Pain
Neuropathic Pain
Nociceptive Pain

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05834998 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated:: 2025-10-06

No Results Yet

NCT05832879 | COMPLETED | NA

33 participants

Telehealth Treatment for Opioid Use Disorders

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-05-01
Completion:: 2025-07-24

Conditions

Opioid Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT05832138 | NOT_YET_RECRUITING | NA

900 participants

ONLOOP Trial: Evaluating a New Surveillance and Support System for Survivors of Childhood Cancer in Ontario

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2025-10-31
Completion:: 2027-11-30

Conditions

Survivorship
Cancer
Heart Diseases
Secondary Cancer
Colorectal Cancer
Breast Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT05804851 | ACTIVE_NOT_RECRUITING

237 participants

Skin Microbiome of Chinese Population Cohort Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-05-08
Completion:: 2025-12-31

Conditions

Skin Microbiome

No Results Yet

NCT05762367 | COMPLETED | NA

40 participants

MR Lymphatic Imaging in Idiopathic Intracranial Hypertention

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-03-10
Completion:: 2025-04-11

Conditions

Idiopathic Intracranial Hypertension

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05734560 | RECRUITING | PHASE1/PHASE2

50 participants

D2C7-IT and 2141-V11 in Newly Diagnosed GBM Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-09-06
Completion:: 2026-10-31

Conditions

Newly Diagnosed MGMT Unmethylated Glioblastoma

Interventions

DRUG

No Results Yet

NCT05716945 | RECRUITING | PHASE4

342 participants

The OPTIMISE Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-07-29
Completion:: 2028-09-30

Conditions

Pseudophakic Bullous Keratopathy
Fuchs' Endothelial Dystrophy
Intraocular Pressure

Interventions

DRUG
OTHER

No Results Yet

NCT05699772 | ACTIVE_NOT_RECRUITING | NA

85 participants

Expanding Delivery of an Evidence-based Weight-loss Intervention to Enhance Access and Reach Underserved Groups After TBI

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-05-25
Completion:: 2026-08-31

Conditions

Traumatic Brain Injury

Interventions

BEHAVIORAL

No Results Yet

NCT05675527 | RECRUITING | PHASE4

135 participants

PRP for Glenohumeral Osteoarthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-05-02
Completion:: 2026-09-01

Conditions

Shoulder Osteoarthritis

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT05672927 | RECRUITING | PHASE4

618 participants

Comparing Immune Response of 2 vs 3 HPV Doses (27-45 Years Old)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-01-18
Completion:: 2026-08-31

Conditions

Immunization
HPV Infection
Human Papillomavirus

Interventions

BIOLOGICAL

No Results Yet

NCT05672381 | COMPLETED

15 participants

NIRST and ICG-based Perfusion Imaging in Acute Compartment Syndrome

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-05-12
Completion:: 2025-09-16

Conditions

Compartment Syndromes
Compartment Syndrome of Lower Leg
Compartment Syndrome of Forearm

Interventions

PROCEDURE

No Results Yet

NCT05624359 | SUSPENDED | NA

216 participants

Flurbiprofen Axetil as an Adjuvant to Pre-emptive Scalp Infiltration

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-11-01
Completion:: 2026-03-01

Conditions

Postoperative Pain

Interventions

DRUG

No Results Yet

NCT05599334 | COMPLETED

111 participants

A Retrospective Observational Study of Patients With Early-stage HER2-positive Breast Cancer, Treated With Neratinib

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2022-07-05
Completion:: 2023-01-30

Conditions

Breast Cancer
Adjuvant Therapy
HER2-positive Breast Cancer

Results Available

NCT05591924 | RECRUITING

1000 participants

Early Severe Illness TrAnslational BioLogy InformaticS in Humans

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-04-26
Completion:: 2034-12-31

Conditions

Sepsis
ARDS
Critical Illness
Neurocognitive Dysfunction
Shock, Septic
Ventilator Associated Pneumonia
Immune Suppression
Inflammation
SIRS

Interventions

PROCEDURE

No Results Yet

NCT05589155 | RECRUITING | NA

30 participants

Efficacy of Using Mobile Health Applications for Health

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2022-10-01
Completion:: 2028-07-01

Conditions

Diabetes Mellitus, Type 2
Obesity

Interventions

OTHER

No Results Yet

NCT05571696 | COMPLETED | NA

84 participants

Mind Matters: A High Touch, Low Cost Approach to Improving Mental Health Outcomes in Patients With Psoriatic Diseases

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2022-10-27
Completion:: 2025-03-31

Conditions

Arthritis, Psoriatic
Psoriasis

Interventions

BEHAVIORAL

No Results Yet

NCT05571319 | COMPLETED | PHASE2

30 participants

A Pilot Study of Metformin to Reduce Cerebrovascular Dysfunction in Participants With HIV and Metabolic Syndrome.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2022-08-11
Completion:: 2025-03-24

Conditions

Metabolic Syndrome
HIV Seropositivity

Interventions

DRUG

No Results Yet

NCT05558059 | RECRUITING

16 participants

Imaging Retinal Vasculature in Infant Eyes

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-10-03
Completion:: 2027-08-31

Conditions

Retinopathy of Prematurity

Interventions

DEVICE

No Results Yet

NCT05513378 | COMPLETED | NA

300 participants

Ultrasound-guided Subclavian Vein Catheterisation With a Needle Guide

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2022-11-08
Completion:: 2025-09-16

Conditions

Complications; Catheter, Mechanical
Catheterization, Central Venous

Interventions

DEVICE

No Results Yet

NCT05507333 | COMPLETED | NA

26 participants

Clinical Performance of the Gedea Pessary in Adult Women With Vulvovaginal Candidiasis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-03-16
Completion:: 2024-02-22

Conditions

Vulvovaginal Candidiasis

Interventions

DEVICE

Results Available