Clinical Trials Updated in 2025

NCT05379322 | WITHDRAWN | PHASE3

0 participants

The Use of Synovial Biopsies in Predicting Response to Biologic Therapy in Rheumatoid Arthritis Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-03-01
Completion:: 2023-03-01

Conditions

Rheumatoid Arthritis

Interventions

DRUG

No Results Yet

NCT05377034 | RECRUITING | PHASE2

100 participants

Multinational Phase II Trial to Compare Safety and Efficacy of SIRT (Y-90 Resin Microspheres) Followed by Atezolizumab Plus Bevacizumab, vs SIRT (SIRT-Y90) Followed by Placebo in Locally Advanced HCC Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2022-10-26
Completion:: 2026-07-25

Conditions

Locally Advanced Hepatocellular Carcinoma

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05365958 | COMPLETED | NA

128 participants

Podcasting HIV Prevention Within African American Communities

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2022-02-11
Completion:: 2023-10-31

Conditions

HIV Prevention

Interventions

BEHAVIORAL

Results Available

NCT05361031 | COMPLETED | PHASE1/PHASE2

12 participants

The Safety and Tolerability of Engensis (VM202) in Patients With Charcot-Marie-Tooth Disease Subtype 1A (CMT1A)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2020-09-21
Completion:: 2021-09-09

Conditions

CMT

Interventions

BIOLOGICAL

Results Available

NCT05313334 | TERMINATED | NA

50 participants

GAMBIT Task With PTSD and Healthy Control Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2022-11-18
Completion:: 2024-10-29

Conditions

Posttraumatic Stress Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT05308966 | COMPLETED

204 participants

Observational Study in Patients With Previously Unresectable Malignant Pleural Mesothelioma Treated With Nivolumab and Ipilimumab (MESO-IMMUNE)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2022-05-03
Completion:: 2025-08-27

Conditions

Malignant Pleural Mesothelioma
Unresectable Malignant Neoplasm

Interventions

OTHER

No Results Yet

NCT05284747 | ACTIVE_NOT_RECRUITING | PHASE4

6019 participants

EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2022-10-26
Completion:: 2027-05-29

Conditions

Cardiovascular Disease
Myocardial Infarction
Stroke
Coronary Revascularization

Interventions

DRUG

No Results Yet

NCT05279729 | RECRUITING | NA

45 participants

Efficacy of mHealth Apps for Health in a Low-income, Type II Diabetic, Hispanic Population

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2022-08-01
Completion:: 2028-10-31

Conditions

Diabetes Mellitus, Type 2
Obesity

Interventions

OTHER

No Results Yet

NCT05244928 | COMPLETED | NA

131 participants

Team Training and Medication Administration in an Ambulance Service

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2022-01-24
Completion:: 2024-01-31

Conditions

Patient Safety
Medication Administration

Interventions

OTHER

No Results Yet

NCT05224505 | ACTIVE_NOT_RECRUITING | PHASE1

6 participants

ATA-100 (Formerly GNT0006) Gene Therapy Trial in Patients With LGMDR9

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2022-09-01
Completion:: 2025-02-01

Conditions

LGMDR9

Interventions

BIOLOGICAL

No Results Yet

NCT05220865 | COMPLETED | NA

268 participants

Hall Technique or Modified Hall Technique of Deep Carious Lesions in Primary Molars

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2022-02-01
Completion:: 2023-09-01

Conditions

Dental Caries in Children
Tooth Diseases
Tooth Demineralization
Stomatognathic Diseases

Interventions

PROCEDURE

No Results Yet

NCT05215236 | COMPLETED | NA

72 participants

Opiate Sparing Protocol Randomized Controlled Trial in Open Distal Radius Fracture Repair

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2022-03-01
Completion:: 2024-05-31

Conditions

Distal Radius Fracture

Interventions

OTHER

No Results Yet

NCT05205512 | COMPLETED | NA

10 participants

Telehealth Exercise Intervention to Improve Cardiovascular Health in Lymphoma Survivors, TECHS Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2022-09-14
Completion:: 2025-06-09

Conditions

Hodgkin Lymphoma
Non-Hodgkin Lymphoma

Interventions

OTHER

No Results Yet

NCT05176093 | COMPLETED | PHASE2

8 participants

A 6-Month Extension Study to Assess the Long-Term Safety of Engensis in Amyotrophic Lateral Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2021-11-14
Completion:: 2022-12-29

Conditions

Amyotrophic Lateral Sclerosis

Interventions

BIOLOGICAL
OTHER

Results Available

NCT05125731 | COMPLETED | NA

72 participants

Effect of Parental Absence on Child's Dental Anxiety and Behaviors During Dental Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2021-10-01
Completion:: 2022-01-01

Conditions

Dental Anxiety
Children, Only
Dental Caries

Interventions

BEHAVIORAL

No Results Yet

NCT05098158 | COMPLETED | NA

21 participants

Community-Engaged Options to Facilitate Opioid Reduction

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2020-07-10
Completion:: 2022-01-03

Conditions

Chronic Pain

Interventions

OTHER

Results Available

NCT05072691 | RECRUITING

100 participants

Prognostic Value of Cerebrospinal Fluid Immunoglobulin Free Light Chains in Patients With Multiple Sclerosis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2020-07-14
Completion:: 2030-01-01

Conditions

Multiple Sclerosis

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05034835 | RECRUITING | NA

60 participants

Impact of Compression Garments on Pain in Patients With Complex Regional Pain Syndrome of the Upper Limbs.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2021-10-12
Completion:: 2026-05-31

Conditions

Complex Regional Pain Syndromes

Interventions

DEVICE
OTHER

No Results Yet

NCT04960241 | COMPLETED | NA

169 participants

Does Rehabilitation After Total Hip Or Knee Arthroplasty Work (DRAW2)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2021-04-06
Completion:: 2024-03-22

Conditions

Rehabilitation
Telerehabilitation
Arthroplasty, Replacement, Hip
Arthroplasty, Replacement, Knee

Interventions

PROCEDURE

No Results Yet

NCT04917601 | RECRUITING | NA

680 participants

A Multicenter Study for Evaluating a Digital Support System in Childhood Obesity Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2022-05-24
Completion:: 2027-12-31

Conditions

Childhood Obesity
Adolescent Obesity
mHealth
Personalized Medicine

Interventions

BEHAVIORAL

No Results Yet

NCT04898010 | SUSPENDED | NA

10 participants

The Selective Cytopheretic Device (SCD) for Acute Kidney Injury (AKI) and Hepatorenal Syndrome (HRS) Type I

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2022-06-09
Completion:: 2027-10-31

Conditions

Acute Kidney Injury
Hepatorenal Syndrome

Interventions

DEVICE

No Results Yet

NCT04896255 | RECRUITING

33000 participants

Long-term Outcomes of Anti-viral Therapies in Patients With Chronic Viral Hepatitis B

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2020-09-09
Completion:: 2026-11-01

Conditions

Chronic Hepatitis b

Interventions

DRUG

No Results Yet

NCT04711330 | ACTIVE_NOT_RECRUITING

126 participants

Response and Toxicity Prediction by Microbiome Analysis After (Concurrent) Chemoradiotherapy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2022-09-01
Completion:: 2025-10-01

Conditions

Non Small Cell Lung Cancer Stage III
Immunotherapy

No Results Yet

NCT04637984 | COMPLETED | NA

200 participants

The Implementation of PREP2 Algorithm Into Clinical Practice

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2019-05-27
Completion:: 2022-12-20

Conditions

Stroke
Rehabilitation

Interventions

BEHAVIORAL

No Results Yet

NCT04635111 | RECRUITING

30 participants

A Long-term Study Evaluating Hepatotoxicity Associated With TURALIO™ (Pexidartinib) Treatment

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2021-01-07
Completion:: 2036-06-01

Conditions

Hepatotoxicity
Tenosynovial Giant Cell Tumor

Interventions

DRUG

No Results Yet

NCT04632225 | COMPLETED | PHASE2

18 participants

Safety of Engensis in Participants With Amyotrophic Lateral Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2021-03-09
Completion:: 2022-07-11

Conditions

Amyotrophic Lateral Sclerosis

Interventions

BIOLOGICAL
OTHER

Results Available

NCT04613310 | COMPLETED | NA

949 participants

PCR and Rapid Diagnostic Test on Saliva and Nasopharyngeal Swabs for the Detection of SARS-CoV-2 (COVID-19)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2020-09-25
Completion:: 2020-12-31

Conditions

COVID-19
SARS-CoV-2

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04526886 | COMPLETED | NA

52 participants

Clinical Trial of a Novel Dose Adjustment Algorithm for Preventing Cytopenia-Related Delays During FOLFOX Chemotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2020-10-15
Completion:: 2023-03-07

Conditions

Colorectal Cancer
Gastric Cancer
Esophageal Cancer
Ampullary Cancer
Small Bowel Cancer
Appendix Cancer

Interventions

OTHER

Results Available

NCT04437667 | SUSPENDED | NA

1000 participants

HIV-Prevention Smartphone Game Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2020-10-12
Completion:: 2028-08-31

Conditions

HIV

Interventions

BEHAVIORAL

No Results Yet

NCT04344613 | WITHDRAWN | NA

0 participants

Evaluation of the Clinical Performances of a Point of Care Analyzer Enabling Pre-transfusion ABOD Group Ultimate Verification at the Patient Bedside

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2020-04-10
Completion:: 2025-10-01

Conditions

Blood Transfusion Complication

Interventions

DEVICE

No Results Yet

NCT04183283 | COMPLETED | PHASE1

16 participants

A Study of LY3526318 in Healthy Women

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2019-12-12
Completion:: 2020-02-28

Conditions

Healthy

Interventions

DRUG

Results Available

NCT04136912 | TERMINATED | PHASE2

27 participants

3-D Super Resolution Ultrasound Microvascular Imaging

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2022-05-26
Completion:: 2024-08-01

Conditions

Breast Cancer
Thyroid Cancer

Interventions

DRUG
DEVICE

Results Available

NCT04108130 | COMPLETED | NA

794 participants

An Anesthesia-Centered Bundle to Reduce Postoperative Pulmonary Complications: The PRIME-AIR Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2020-01-29
Completion:: 2023-07-13

Conditions

Postoperative Pulmonary Complications

Interventions

OTHER
PROCEDURE
BEHAVIORAL

Results Available

NCT04085835 | COMPLETED

21 participants

Evolution of Menstruation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2020-10-27
Completion:: 2025-04-27

Conditions

Menstruation

No Results Yet

NCT04079530 | COMPLETED | PHASE2

60 participants

A Clinical Pharmacology Study of K-877 Controlled Release Tablet

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2019-09-13
Completion:: 2019-12-24

Conditions

Dyslipidemias

Interventions

DRUG

No Results Yet

NCT04047030 | COMPLETED

244 participants

The Mobility Toolkit: Electronically Augmented Assessment of Functional Recovery Following Lower-extremity Trauma

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2019-01-01
Completion:: 2023-12-01

Conditions

Gait

Interventions

OTHER

No Results Yet

NCT04036045 | WITHDRAWN

0 participants

Approaches to Identify Early Biomarkers and Pathogenesis of Anthracycline Cardiotoxicity

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2018-11-12
Completion:: 2024-12-31

Conditions

Childhood Cancer

Interventions

OTHER

No Results Yet

NCT03981926 | COMPLETED | NA

300 participants

Team-Based Connected Health (TCH) to Improve Clinical Outcomes and Access in Atopic Dermatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2019-08-27
Completion:: 2024-02-28

Conditions

Atopic Dermatitis Eczema
Atopic Dermatitis
Eczema

Interventions

OTHER

Results Available

NCT03972150 | COMPLETED | PHASE1

21 participants

A Study to Find the Best Dose of BI 836880 Alone and in Combination With BI 754091 in Japanese Patients With Different Types of Advanced Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2019-06-12
Completion:: 2020-10-27

Conditions

Neoplasms

Interventions

DRUG

Results Available

NCT03963518 | COMPLETED

631 participants

Immune-checkpoint Inhibitors and Surrogate Endpoints in Cancer Trials (SURROGATE-ICI)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2017-01-31
Completion:: 2020-12-31

Conditions

Cancer Treated With Immune-checkpoint Inhibitors

Interventions

DRUG

Results Available